IL-17 mediates inflammatory reactions via p38/c-Fos and JNK/c-Jun activation in an AP-1-dependent manner in human nucleus pulposus cells

Journal of Translational Medicine

Volumn 14, Issue 1, 2016, Pages

  Li, Jing Kun ^a   Nie, Lin ^a   Zhao, Yun Peng ^a   Zhang, Yuan Qiang ^a   Wang, Xiaoqing ^b   Wang, Shuai Shuai ^a   Liu, Yi ^a   Zhao, Hua ^a   Cheng, Lei ^a,c  

^a SHANDONG UNIVERSITY   (China)

^b SHANGHAI SECOND MEDICAL UNIVERSITY   (China)

^c Key Laboratory of Cardiovascular Proteomics of Shandong Province   (China)

Author keywords

AP 1; COX2; IL 17; LBP; MAPK; PGE2

Indexed keywords

CYCLOOXYGENASE 2; INTERLEUKIN 17; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROSTAGLANDIN E2; PROTEIN C FOS; PROTEIN C JUN; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR AP 1; PTGS2 PROTEIN, HUMAN;

ARTICLE; CELLS BY BODY ANATOMY; CONTROLLED STUDY; CYTOKINE PRODUCTION; CYTOKINE RELEASE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; INTERVERTEBRAL DISK DEGENERATION; INTRACELLULAR SIGNALING; MOLECULAR DYNAMICS; NERVOUS SYSTEM INFLAMMATION; NEUROSURGERY; NUCLEUS PULPOSUS; NUCLEUS PULPOSUS CELL; PROTEIN EXPRESSION; PROTEIN FUNCTION; TIME SERIES ANALYSIS; TREND STUDY; UPREGULATION; ADULT; BIOLOGICAL MODEL; BIOSYNTHESIS; CELL CULTURE; DRUG EFFECT; FEMALE; INFLAMMATION; INTERVERTEBRAL DISK; MALE; MAPK SIGNALING; METABOLISM; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION; TIME FACTOR; YOUNG ADULT;

ADULT; CELLS, CULTURED; CYCLOOXYGENASE 2; DINOPROSTONE; ENZYME ACTIVATION; FEMALE; HUMANS; INFLAMMATION; INTERLEUKIN-17; INTERVERTEBRAL DISC; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MAP KINASE SIGNALING SYSTEM; MIDDLE AGED; MODELS, BIOLOGICAL; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PHOSPHORYLATION; PROTO-ONCOGENE PROTEINS C-FOS; TIME FACTORS; TRANSCRIPTION FACTOR AP-1; UP-REGULATION; YOUNG ADULT;

EID: 84977610573     PISSN: None     EISSN: 14795876     Source Type: Journal    
DOI: 10.1186/s12967-016-0833-9     Document Type: Article

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