Oxidative stress induces stem cell proliferation via TRPA1/RyR-mediated Ca2+signaling in the Drosophila midgut

eLife

Volumn 6, Issue , 2017, Pages

  Xu, Chiwei ^a   Luo, Junjie ^b   He, Li ^a   Montell, Craig ^b   Perrimon, Norbert ^a,c  

^a HARVARD MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLEOMYCIN; CALCINEURIN; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; RAF PROTEIN; REACTIVE OXYGEN METABOLITE; RYANODINE RECEPTOR; TRANSIENT RECEPTOR POTENTIAL CHANNEL A1; DROSOPHILA PROTEIN; TRPA1 PROTEIN, DROSOPHILA;

ANIMAL CELL; ARTICLE; CALCIUM SIGNALING; CELL DIFFERENTIATION; CELL PROLIFERATION; CELLULAR STRESS SIGNAL; CONTROLLED STUDY; DNA DAMAGE RESPONSE; DROSOPHILA; ELECTROPHYSIOLOGY; FLUORESCENCE MICROSCOPY; GENE EXPRESSION; GENOTYPE; IMMUNOHISTOCHEMISTRY; INTESTINAL STEM CELL; LUCIFERASE ASSAY; MIDGUT; MITOGENESIS; NONHUMAN; ONCOGENE RAS; OXIDATIVE STRESS; REAL TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RNA INTERFERENCE; STEM CELL SELF-RENEWAL; TISSUE INJURY; ANIMAL; GASTROINTESTINAL TRACT; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; CELL PROLIFERATION; DROSOPHILA; DROSOPHILA PROTEINS; GASTROINTESTINAL TRACT; OXIDATIVE STRESS; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SIGNAL TRANSDUCTION; STEM CELLS; TRPA1 CATION CHANNEL;

EID: 85020383837     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.22441     Document Type: Article

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