Systematic screen of chemotherapeutics in Drosophila stem cell tumors

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 12, 2014, Pages 4530-4535

  Markstein, Michele ^a,b   Dettorre, Samantha ^a,b   Cho, Julio ^b   Neumüller, Ralph A ^b   Craig Müller, Sören ^b   Perrimon, Norbert ^b,c  

^a UNIVERSITY OF MASSACHUSETTS   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

Cancer stem cell; Drosophila intestinal stem cell; Drug screening; Whole animal screening

Indexed keywords

ANTINEOPLASTIC AGENT; BORTEZOMIB; DACTINOMYCIN; DAUNORUBICIN; FUNGAL EXTRACT; GEMCITABINE; HALCINONIDE; HARMALOL; HERBACEOUS AGENT; JANUS KINASE; METHOTREXATE; MITOMYCIN; PACLITAXEL; RAPAMYCIN; SENECIPHYLLINE; STAT PROTEIN; THIOTEPA; TOPOTECAN; VINBLASTINE; VINCRISTINE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CHEMOTHERAPY; CANCER INHIBITION; CANCER STEM CELL; CELL INTERACTION; CONTROLLED STUDY; DROSOPHILA; FOOD AND DRUG ADMINISTRATION; GENE EXPRESSION; GROWTH INHIBITION; IN VIVO STUDY; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; TUMOR RECURRENCE; WILD TYPE;

CANCER STEM CELL; DROSOPHILA INTESTINAL STEM CELL; DRUG SCREENING; WHOLE-ANIMAL SCREENING;

ANIMALS; ANTINEOPLASTIC AGENTS; CELL PROLIFERATION; DISEASE MODELS, ANIMAL; DROSOPHILA; DRUG SCREENING ASSAYS, ANTITUMOR; NEOPLASMS, EXPERIMENTAL; NEOPLASTIC STEM CELLS; TUMOR MICROENVIRONMENT;

EID: 84897011287     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1401160111     Document Type: Article

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