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Volumn 17, Issue 9, 2015, Pages 1182-1192

Niche appropriation by Drosophila intestinal stem cell tumours

Author keywords

[No Author keywords available]

Indexed keywords

CELL PROTEIN; CYTOKINE; EPIDERMAL GROWTH FACTOR RECEPTOR; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG; UPD2 PROTEIN; UPD3 PROTEIN; YKI PROTEIN; DROSOPHILA PROTEIN; EGFR PROTEIN, DROSOPHILA; NOTCH PROTEIN, DROSOPHILA; NOTCH RECEPTOR; RECEPTOR;

EID: 84940591073     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3214     Document Type: Article
Times cited : (118)

References (44)
  • 1
    • 31444444485 scopus 로고    scopus 로고
    • The adult Drosophila posterior midgut is maintained by pluripotent stem cells
    • Ohlstein, B., & Spradling, A. The adult Drosophila posterior midgut is maintained by pluripotent stem cells. Nature. 439, 470-474 (2006
    • (2006) Nature , vol.439 , pp. 470-474
    • Ohlstein, B.1    Spradling, A.2
  • 2
    • 31444452338 scopus 로고    scopus 로고
    • Evidence that stem cells reside in the adult Drosophila midgut epithelium
    • Micchelli, C. A., & Perrimon, N. Evidence that stem cells reside in the adult Drosophila midgut epithelium. Nature. 439, 475-479 (2006
    • (2006) Nature , vol.439 , pp. 475-479
    • Micchelli, C.A.1    Perrimon, N.2
  • 3
    • 80455173895 scopus 로고    scopus 로고
    • Intestinal stem cells in the adult Drosophila midgut
    • Jiang, H., & Edgar, B. A. Intestinal stem cells in the adult Drosophila midgut. Exp. Cell Res. 371, 2780-2788 (2011
    • (2011) Exp. Cell Res , vol.371 , pp. 2780-2788
    • Jiang, H.1    Edgar, B.A.2
  • 4
    • 33847168133 scopus 로고    scopus 로고
    • Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling
    • Ohlstein, B., & Spradling, A. Multipotent Drosophila intestinal stem cells specify daughter cell fates by differential notch signaling. Science. 315, 988-992 (2007
    • (2007) Science , vol.315 , pp. 988-992
    • Ohlstein, B.1    Spradling, A.2
  • 5
    • 64249172203 scopus 로고    scopus 로고
    • The canonical Notch signaling pathway: Unfolding the activation mechanism
    • Kopan, R., & Ilagan, M. X. The canonical Notch signaling pathway: unfolding the activation mechanism. Cell. 137, 216-233 (2009
    • (2009) Cell , vol.137 , pp. 216-233
    • Kopan, R.1    Ilagan, M.X.2
  • 6
    • 80052700259 scopus 로고    scopus 로고
    • Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine
    • Perdigoto, C. N., Schweisguth, F., & Bardin, A. J. Distinct levels of Notch activity for commitment and terminal differentiation of stem cells in the adult fly intestine. Development. 138, 4585-4595 (2011
    • (2011) Development , vol.138 , pp. 4585-4595
    • Perdigoto, C.N.1    Schweisguth, F.2    Bardin, A.J.3
  • 8
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: The next generation
    • Hanahan, D., & Weinberg, R. A. Hallmarks of cancer: the next generation. Cell. 144, 646-674 (2011
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 9
    • 84858590826 scopus 로고    scopus 로고
    • Accessories to the crime: Functions of cells recruited to the tumor microenvironment
    • Hanahan, D., & Coussens, L. M. Accessories to the crime: functions of cells recruited to the tumor microenvironment. Cancer Cell. 21, 309-322 (2012
    • (2012) Cancer Cell , vol.21 , pp. 309-322
    • Hanahan, D.1    Coussens, L.M.2
  • 10
    • 84901271886 scopus 로고    scopus 로고
    • Tissue design: How Drosophila tumors remodel their neighborhood
    • Patel, P. H., & Edgar, B. A. Tissue design: how Drosophila tumors remodel their neighborhood. Semin. Cell Dev. Biol. 28, 86-95 (2014
    • (2014) Semin. Cell Dev. Biol , vol.28 , pp. 86-95
    • Patel, P.H.1    Edgar, B.A.2
  • 11
    • 84870044742 scopus 로고    scopus 로고
    • Nonautonomous crosstalk between the Jak/Stat and EGFR pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut
    • Cordero, J. B., Stefanatos, R. K., Myant, K., Vidal, M., & Sansom, O. J. Nonautonomous crosstalk between the Jak/Stat and Egfr pathways mediates Apc1-driven intestinal stem cell hyperplasia in the Drosophila adult midgut. Development. 139, 4524-4535 (2012
    • (2012) Development , vol.139 , pp. 4524-4535
    • Cordero, J.B.1    Stefanatos, R.K.2    Myant, K.3    Vidal, M.4    Sansom, O.J.5
  • 12
    • 84924541848 scopus 로고    scopus 로고
    • Dpp/Gbb signaling is required for normal intestinal regeneration during infection
    • Zhou, J., et al. Dpp/Gbb signaling is required for normal intestinal regeneration during infection. Dev. Biol. 399, 189-203 (2015
    • (2015) Dev. Biol , vol.399 , pp. 189-203
    • Zhou, J.1
  • 13
    • 73949145172 scopus 로고    scopus 로고
    • Synergy between bacterial infection and genetic predisposition in intestinal dysplasia
    • Apidianakis, Y., Pitsouli, C., Perrimon, N., & Rahme, L. Synergy between bacterial infection and genetic predisposition in intestinal dysplasia. Proc. Natl Acad. Sci. USA. 106, 20883-20888 (2009
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 20883-20888
    • Apidianakis, Y.1    Pitsouli, C.2    Perrimon, N.3    Rahme, L.4
  • 14
    • 84864854371 scopus 로고    scopus 로고
    • Lineage tracing reveals Lgr5C stem cell activity in mouse intestinal adenomas
    • Schepers, A. G., et al. Lineage tracing reveals Lgr5C stem cell activity in mouse intestinal adenomas. Science. 337, 730-735 (2012
    • (2012) Science , vol.337 , pp. 730-735
    • Schepers, A.G.1
  • 15
    • 84861871905 scopus 로고    scopus 로고
    • Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1)
    • Durand, A., et al. Functional intestinal stem cells after Paneth cell ablation induced by the loss of transcription factor Math1 (Atoh1). Proc. Natl Acad. Sci. USA. 109, 8965-8970 (2012
    • (2012) Proc. Natl Acad. Sci. USA , vol.109 , pp. 8965-8970
    • Durand, A.1
  • 16
    • 57249116893 scopus 로고    scopus 로고
    • E-cadherin prolongs the moment for interaction between intestinal stem cell and its progenitor cell to ensure Notch signaling in adult Drosophila midgut
    • Maeda, K., Takemura, M., Umemori, M., & Adachi-Yamada, T. E-cadherin prolongs the moment for interaction between intestinal stem cell and its progenitor cell to ensure Notch signaling in adult Drosophila midgut. Genes Cells 13 1219-1227 2008
    • (2008) Genes Cells , vol.13 , pp. 1219-1227
    • Maeda, K.1    Takemura, M.2    Umemori, M.3    Adachi-Yamada, T.4
  • 17
    • 76449116295 scopus 로고    scopus 로고
    • Transcriptional control of stem cell maintenance in the Drosophila intestine
    • Bardin, A. J., Perdigoto, C. N., Southall, T. D., Brand, A. H., & Schweisguth, F. Transcriptional control of stem cell maintenance in the Drosophila intestine. Development. 137, 705-714 (2010
    • (2010) Development , vol.137 , pp. 705-714
    • Bardin, A.J.1    Perdigoto, C.N.2    Southall, T.D.3    Brand, A.H.4    Schweisguth, F.5
  • 18
    • 67549133157 scopus 로고    scopus 로고
    • Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
    • Jiang, H., et al. Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut. Cell. 137, 1343-1355 (2009
    • (2009) Cell , vol.137 , pp. 1343-1355
    • Jiang, H.1
  • 19
    • 70349617469 scopus 로고    scopus 로고
    • Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila
    • Buchon, N., Broderick, N. A., Chakrabarti, S., & Lemaitre, B. Invasive and indigenous microbiota impact intestinal stem cell activity through multiple pathways in Drosophila. Genes Dev. 23, 2333-2344 (2009
    • (2009) Genes Dev , vol.23 , pp. 2333-2344
    • Buchon, N.1    Broderick, N.A.2    Chakrabarti, S.3    Lemaitre, B.4
  • 20
    • 77956507262 scopus 로고    scopus 로고
    • Warts and Yorkie mediate intestinal regeneration by influencing stem cell proliferation
    • Staley, B. K., & Irvine, K. D. Warts and Yorkie mediate intestinal regeneration by influencing stem cell proliferation. Curr. Biol. 20, 1580-1587 (2010
    • (2010) Curr. Biol , vol.20 , pp. 1580-1587
    • Staley, B.K.1    Irvine, K.D.2
  • 21
    • 78650187792 scopus 로고    scopus 로고
    • The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration
    • Shaw, R. L., et al. The Hippo pathway regulates intestinal stem cell proliferation during Drosophila adult midgut regeneration. Development. 137, 4147-4158 (2010
    • (2010) Development , vol.137 , pp. 4147-4158
    • Shaw, R.L.1
  • 22
    • 78650471357 scopus 로고    scopus 로고
    • Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways
    • Ren, F., et al. Hippo signaling regulates Drosophila intestine stem cell proliferation through multiple pathways. Proc. Natl Acad. Sci. USA. 107, 21064-21069 (2010
    • (2010) Proc. Natl Acad. Sci. USA , vol.107 , pp. 21064-21069
    • Ren, F.1
  • 23
    • 78650202455 scopus 로고    scopus 로고
    • The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration
    • Karpowicz, P., Perez, J., & Perrimon, N. The Hippo tumor suppressor pathway regulates intestinal stem cell regeneration. Development. 137, 4135-4145 (2010
    • (2010) Development , vol.137 , pp. 4135-4145
    • Karpowicz, P.1    Perez, J.2    Perrimon, N.3
  • 24
    • 84936120034 scopus 로고    scopus 로고
    • Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine
    • Kohlmaier, A., et al. Src kinase function controls progenitor cell pools during regeneration and tumor onset in the Drosophila intestine. Oncogene. 34, 2371-2384 (2014
    • (2014) Oncogene , vol.34 , pp. 2371-2384
    • Kohlmaier, A.1
  • 25
    • 78650977190 scopus 로고    scopus 로고
    • EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila
    • Jiang, H., Grenley, M. O., Bravo, M. J., Blumhagen, R. Z., & Edgar, B. A. EGFR/Ras/MAPK signaling mediates adult midgut epithelial homeostasis and regeneration in Drosophila. Cell Stem Cell. 8, 84-95 (2011
    • (2011) Cell Stem Cell , vol.8 , pp. 84-95
    • Jiang, H.1    Grenley, M.O.2    Bravo, M.J.3    Blumhagen, R.Z.4    Edgar, B.A.5
  • 26
    • 79955521176 scopus 로고    scopus 로고
    • EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells
    • Xu, N., et al. EGFR, Wingless and JAK/STAT signaling cooperatively maintain Drosophila intestinal stem cells. Dev. Biol. 354, 31-43 (2011
    • (2011) Dev. Biol , vol.354 , pp. 31-43
    • Xu, N.1
  • 27
    • 78650397479 scopus 로고    scopus 로고
    • Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection
    • Buchon, N., Broderick, N. A., Kuraishi, T., & Lemaitre, B. Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol. 8, 152 (2010
    • (2010) BMC Biol , vol.8 , pp. 152
    • Buchon, N.1    Broderick, N.A.2    Kuraishi, T.3    Lemaitre, B.4
  • 28
    • 79955133184 scopus 로고    scopus 로고
    • EGF signaling regulates the proliferation of intestinal stem cells in Drosophila
    • Biteau, B., & Jasper, H. EGF signaling regulates the proliferation of intestinal stem cells in Drosophila. Development. 138, 1045-1055 (2011
    • (2011) Development , vol.138 , pp. 1045-1055
    • Biteau, B.1    Jasper, H.2
  • 29
    • 58049218983 scopus 로고    scopus 로고
    • Tissue damage-induced intestinal stem cell division in Drosophila
    • Amcheslavsky, A., Jiang, J., & Ip, Y. T. Tissue damage-induced intestinal stem cell division in Drosophila. Cell Stem Cell. 4, 49-61 (2009
    • (2009) Cell Stem Cell , vol.4 , pp. 49-61
    • Amcheslavsky, A.1    Jiang, J.2    Ip, Y.T.3
  • 30
    • 84902290549 scopus 로고    scopus 로고
    • Drosophila perlecan regulates intestinal stem cell activity via cell-matrix attachment
    • You, J., et al. Drosophila perlecan regulates intestinal stem cell activity via cell-matrix attachment. Stem Cell Rep. 2, 761-769 (2014
    • (2014) Stem Cell Rep , vol.2 , pp. 761-769
    • You, J.1
  • 31
    • 84860109015 scopus 로고    scopus 로고
    • Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia
    • Eisenhoffer, G. T., et al. Crowding induces live cell extrusion to maintain homeostatic cell numbers in epithelia. Nature. 484, 546-549 (2012
    • (2012) Nature , vol.484 , pp. 546-549
    • Eisenhoffer, G.T.1
  • 32
    • 77950455135 scopus 로고    scopus 로고
    • JAK-STAT is restrained by Notch to control cell proliferation of the Drosophila intestinal stem cells
    • Liu, W., Singh, S. R., & Hou, S. X. JAK-STAT is restrained by Notch to control cell proliferation of the Drosophila intestinal stem cells. J. Cell Biochem. 109, 992-999 (2010
    • (2010) J. Cell Biochem , vol.109 , pp. 992-999
    • Liu, W.1    Singh, S.R.2    Hou, S.X.3
  • 33
    • 84864981200 scopus 로고    scopus 로고
    • Autocrine platelet-derived growth factor-vascular endothelial growth factor receptor-related (Pvr) pathway activity controls intestinal stem cell proliferation in the adult Drosophila midgut
    • Bond, D., & Foley, E. Autocrine platelet-derived growth factor-vascular endothelial growth factor receptor-related (Pvr) pathway activity controls intestinal stem cell proliferation in the adult Drosophila midgut. J. Biol. Chem. 287, 27359-27370 (2012
    • (2012) J. Biol. Chem , vol.287 , pp. 27359-27370
    • Bond, D.1    Foley, E.2
  • 34
    • 81755187019 scopus 로고    scopus 로고
    • Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathway
    • Choi, N. H., Lucchetta, E., & Ohlstein, B. Nonautonomous regulation of Drosophila midgut stem cell proliferation by the insulin-signaling pathway. Proc. Natl Acad. Sci. USA. 108, 18702-18707 (2011
    • (2011) Proc. Natl Acad. Sci. USA , vol.108 , pp. 18702-18707
    • Choi, N.H.1    Lucchetta, E.2    Ohlstein, B.3
  • 35
    • 80155123827 scopus 로고    scopus 로고
    • Altered modes of stem cell division drive adaptive intestinal growth
    • O Brien, L. E., Soliman, S. S., Li, X., & Bilder, D. Altered modes of stem cell division drive adaptive intestinal growth. Cell. 147, 603-614 (2011
    • (2011) Cell , vol.147 , pp. 603-614
    • Brien L E O..1    Soliman, S.S.2    Li, X.3    Bilder, D.4
  • 36
    • 54549104587 scopus 로고    scopus 로고
    • Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells
    • Lin, G., Xu, N., & Xi, R. Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells. Nature. 455, 1119-1123 (2008
    • (2008) Nature , vol.455 , pp. 1119-1123
    • Lin, G.1    Xu, N.2    Xi, R.3
  • 37
    • 84867103410 scopus 로고    scopus 로고
    • Inducible progenitor-derived Wingless regulates adult midgut regeneration in Drosophila
    • Cordero, J. B., Stefanatos, R. K., Scopelliti, A., Vidal, M., & Sansom, O. J. Inducible progenitor-derived Wingless regulates adult midgut regeneration in Drosophila. EMBO J. 31, 3901-3917 (2012
    • (2012) EMBO J , vol.31 , pp. 3901-3917
    • Cordero, J.B.1    Stefanatos, R.K.2    Scopelliti, A.3    Vidal, M.4    Sansom, O.J.5
  • 38
    • 73549097743 scopus 로고    scopus 로고
    • JAK/STAT signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage
    • Beebe, K., Lee, W. C., & Micchelli, C. A. JAK/STAT signaling coordinates stem cell proliferation and multilineage differentiation in the Drosophila intestinal stem cell lineage. Dev. Biol. 338, 28-37 (2010
    • (2010) Dev. Biol , vol.338 , pp. 28-37
    • Beebe, K.1    Lee, W.C.2    Micchelli, C.A.3
  • 39
    • 77950367306 scopus 로고    scopus 로고
    • Paracrine unpaired signaling through the JAK/STAT pathway controls self-renewal and lineage differentiation of Drosophila intestinal stem cells
    • Lin, G., Xu, N., & Xi, R. Paracrine unpaired signaling through the JAK/STAT pathway controls self-renewal and lineage differentiation of Drosophila intestinal stem cells. J. Mol. Cell Biol. 2, 37-49 (2010
    • (2010) J. Mol. Cell Biol , vol.2 , pp. 37-49
    • Lin, G.1    Xu, N.2    Xi, R.3
  • 40
    • 84867363816 scopus 로고    scopus 로고
    • The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells
    • Goulas, S., Conder, R., & Knoblich, J. A. The Par complex and integrins direct asymmetric cell division in adult intestinal stem cells. Cell Stem Cell. 11, 529-540 (2012
    • (2012) Cell Stem Cell , vol.11 , pp. 529-540
    • Goulas, S.1    Conder, R.2    Knoblich, J.A.3
  • 41
    • 84876311627 scopus 로고    scopus 로고
    • Integrin signaling is required for maintenance and proliferation of intestinal stem cells in Drosophila
    • Lin, G., et al. Integrin signaling is required for maintenance and proliferation of intestinal stem cells in Drosophila. Dev. Biol. 377, 177-187 (2013
    • (2013) Dev. Biol , vol.377 , pp. 177-187
    • Lin, G.1
  • 42
    • 84895858857 scopus 로고    scopus 로고
    • Integrin inhibits chronic and high level activation of JNK to repress senescence phenotypes in Drosophila adult midgut
    • Okumura, T., Takeda, K., Taniguchi, K., & Adachi-Yamada, T. -integrin inhibits chronic and high level activation of JNK to repress senescence phenotypes in Drosophila adult midgut. PLoS ONE 9 e89387 (2014
    • (2014) PLoS ONE , vol.9 , pp. e89387
    • Okumura, T.1    Takeda, K.2    Taniguchi, K.3    Adachi-Yamada, T.4
  • 43
    • 0042697323 scopus 로고    scopus 로고
    • Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury
    • Agaisse, H., et al. Signaling role of hemocytes in Drosophila JAK/STAT-dependent response to septic injury. Dev. Cell. 5, 441-450 (2003
    • (2003) Dev. Cell , vol.5 , pp. 441-450
    • Agaisse, H.1
  • 44
    • 84891721038 scopus 로고    scopus 로고
    • RNA expression profiling from FACS-isolated cells of the Drosophila intestine
    • Unit. 2F. 2
    • Dutta, D., Xiang, J., & Edgar, B. A. RNA expression profiling from FACS-isolated cells of the Drosophila intestine. Curr. Protoc. Stem Cell Biol. 27, Unit. 2F. 2 (2013
    • (2013) Curr. Protoc. Stem Cell Biol , vol.27
    • Dutta, D.1    Xiang, J.2    Edgar, B.A.3


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