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Volumn 528, Issue 7581, 2015, Pages 212-217

Signal integration by Ca 2+ regulates intestinal stem-cell activity

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; GLUTAMIC ACID; METABOTROPIC RECEPTOR; N METHYL DEXTRO ASPARTIC ACID; CALCIUM;

EID: 84949798263     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16170     Document Type: Article
Times cited : (144)

References (55)
  • 1
    • 80155123827 scopus 로고    scopus 로고
    • Altered modes of stem cell division drive adaptive intestinal growth
    • O'Brien, L. E., Soliman, S. S., Li, X. & Bilder, D. Altered modes of stem cell division drive adaptive intestinal growth. Cell 147, 603-614 (2011).
    • (2011) Cell , vol.147 , pp. 603-614
    • O'Brien, L.E.1    Soliman, S.S.2    Li, X.3    Bilder, D.4
  • 2
    • 84882709450 scopus 로고    scopus 로고
    • Gut homeostasis in a microbial world: Insights from Drosophila melanogaster
    • Buchon, N., Broderick, N. A. & Lemaitre, B. Gut homeostasis in a microbial world: Insights from Drosophila melanogaster. Nature Rev. Microbiol. 11, 615-626 (2013).
    • (2013) Nature Rev. Microbiol. , vol.11 , pp. 615-626
    • Buchon, N.1    Broderick, N.A.2    Lemaitre, B.3
  • 3
    • 80755174406 scopus 로고    scopus 로고
    • Maintaining tissue homeostasis: Dynamic control of somatic stem cell activity
    • Biteau, B., Hochmuth, C. E. & Jasper, H. Maintaining tissue homeostasis: Dynamic control of somatic stem cell activity. Cell Stem Cell 9, 402-411 (2011).
    • (2011) Cell Stem Cell , vol.9 , pp. 402-411
    • Biteau, B.1    Hochmuth, C.E.2    Jasper, H.3
  • 4
    • 84888602564 scopus 로고    scopus 로고
    • The digestive tract of Drosophila melanogaster
    • Lemaitre, B. & Miguel-Aliaga, I. The digestive tract of Drosophila melanogaster. Annu. Rev. Genet. 47, 377-404 (2013).
    • (2013) Annu. Rev. Genet. , vol.47 , pp. 377-404
    • Lemaitre, B.1    Miguel-Aliaga, I.2
  • 5
    • 84897928013 scopus 로고    scopus 로고
    • Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster
    • Ayyaz, A. & Jasper, H. Intestinal inflammation and stem cell homeostasis in aging Drosophila melanogaster. Front. Cell. Infect. Microbiol. 3, 98 (2013).
    • (2013) Front. Cell. Infect. Microbiol. , vol.3 , pp. 98
    • Ayyaz, A.1    Jasper, H.2
  • 6
    • 47049101814 scopus 로고    scopus 로고
    • Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster
    • Skorupa, D. A., Dervisefendic, A., Zwiener, J. & Pletcher, S. D. Dietary composition specifies consumption, obesity, and lifespan in Drosophila melanogaster. Aging Cell 7, 478-490 (2008).
    • (2008) Aging Cell , vol.7 , pp. 478-490
    • Skorupa, D.A.1    Dervisefendic, A.2    Zwiener, J.3    Pletcher, S.D.4
  • 7
    • 40649107876 scopus 로고    scopus 로고
    • Lifespan and reproduction in Drosophila: New insights from nutritional geometry
    • Lee, K. P. et al. Lifespan and reproduction in Drosophila: New insights from nutritional geometry. Proc. Natl Acad. Sci. USA 105, 2498-2503 (2008).
    • (2008) Proc. Natl Acad. Sci. USA , vol.105 , pp. 2498-2503
    • Lee, K.P.1
  • 10
    • 84901020488 scopus 로고    scopus 로고
    • Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition
    • Xiao, W. et al. Glutamate prevents intestinal atrophy via luminal nutrient sensing in a mouse model of total parenteral nutrition. FASEB J. 28, 2073-2087 (2014).
    • (2014) FASEB J. , vol.28 , pp. 2073-2087
    • Xiao, W.1
  • 11
    • 67549133157 scopus 로고    scopus 로고
    • Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut
    • Jiang, H. et al. Cytokine/Jak/Stat signaling mediates regeneration and homeostasis in the Drosophila midgut. Cell 137, 1343-1355 (2009).
    • (2009) Cell , vol.137 , pp. 1343-1355
    • Jiang, H.1
  • 12
    • 0035341376 scopus 로고    scopus 로고
    • Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development
    • Lee, T. & Luo, L. Mosaic analysis with a repressible cell marker (MARCM) for Drosophila neural development. Trends Neurosci. 24, 251-254 (2001).
    • (2001) Trends Neurosci. , vol.24 , pp. 251-254
    • Lee, T.1    Luo, L.2
  • 13
    • 84872191631 scopus 로고    scopus 로고
    • The cystine/glutamate antiporter system xc ? in health and disease: From molecular mechanisms to novel therapeutic opportunities
    • Lewerenz, J. et al. The cystine/glutamate antiporter system xc ? in health and disease: From molecular mechanisms to novel therapeutic opportunities. Antioxid. Redox Signal. 18, 522-555 (2013).
    • (2013) Antioxid. Redox Signal. , vol.18 , pp. 522-555
    • Lewerenz, J.1
  • 14
    • 0029719789 scopus 로고    scopus 로고
    • Desensitization of G protein-coupled receptors
    • discussion 352-313
    • Freedman, N. J. & Lefkowitz, R. J. Desensitization of G protein-coupled receptors. Recent Prog. Horm. Res. 51, 319-351; discussion 352-313 (1996).
    • (1996) Recent Prog. Horm. Res. , vol.51 , pp. 319-351
    • Freedman, N.J.1    Lefkowitz, R.J.2
  • 15
    • 0035001341 scopus 로고    scopus 로고
    • Glutamate uptake
    • Danbolt, N. C. Glutamate uptake. Prog. Neurobiol. 65, 1-105 (2001).
    • (2001) Prog. Neurobiol. , vol.65 , pp. 1-105
    • Danbolt, N.C.1
  • 16
    • 70349571341 scopus 로고    scopus 로고
    • Metabolic fate and function of dietary glutamate in the gut
    • Burrin, D. G. & Stoll, B. Metabolic fate and function of dietary glutamate in the gut. Am. J. Clin. Nutr. 90, 850S-856S (2009).
    • (2009) Am. J. Clin. Nutr. , vol.90 , pp. 850-856
    • Burrin, D.G.1    Stoll, B.2
  • 17
    • 1842816630 scopus 로고    scopus 로고
    • Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain
    • Rival, T. et al. Decreasing glutamate buffering capacity triggers oxidative stress and neuropil degeneration in the Drosophila brain. Curr. Biol. 14, 599-605 (2004).
    • (2004) Curr. Biol. , vol.14 , pp. 599-605
    • Rival, T.1
  • 18
    • 84892441178 scopus 로고    scopus 로고
    • Dpp signaling determines regional stem cell identity in the regenerating adult Drosophila gastrointestinal tract
    • Li, H., Qi, Y. & Jasper, H. Dpp signaling determines regional stem cell identity in the regenerating adult Drosophila gastrointestinal tract. Cell Rep 4, 10-18 (2013).
    • (2013) Cell Rep , vol.4 , pp. 10-18
    • Li, H.1    Qi, Y.2    Jasper, H.3
  • 19
    • 20044388322 scopus 로고    scopus 로고
    • Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome
    • McBride, S. M. et al. Pharmacological rescue of synaptic plasticity, courtship behavior, and mushroom body defects in a Drosophila model of fragile X syndrome. Neuron 45, 753-764 (2005).
    • (2005) Neuron , vol.45 , pp. 753-764
    • McBride, S.M.1
  • 20
    • 70349653079 scopus 로고    scopus 로고
    • Calcium pumps in health and disease
    • Brini, M. & Carafoli, E. Calcium pumps in health and disease. Physiol. Rev. 89, 1341-1378 (2009).
    • (2009) Physiol. Rev. , vol.89 , pp. 1341-1378
    • Brini, M.1    Carafoli, E.2
  • 22
    • 37149029370 scopus 로고    scopus 로고
    • Calcium signaling
    • Clapham, D. E. Calcium signaling. Cell 131, 1047-1058 (2007).
    • (2007) Cell , vol.131 , pp. 1047-1058
    • Clapham, D.E.1
  • 23
    • 84889599204 scopus 로고    scopus 로고
    • Olfactory control of blood progenitor maintenance
    • Shim, J. et al. Olfactory control of blood progenitor maintenance. Cell 155, 1141-1153 (2013).
    • (2013) Cell , vol.155 , pp. 1141-1153
    • Shim, J.1
  • 24
    • 73349108496 scopus 로고    scopus 로고
    • Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators
    • Tian, L. et al. Imaging neural activity in worms, flies and mice with improved GCaMP calcium indicators. Nature Methods 6, 875-881 (2009).
    • (2009) Nature Methods , vol.6 , pp. 875-881
    • Tian, L.1
  • 25
    • 84867026349 scopus 로고    scopus 로고
    • Optimization of a GCaMP calcium indicator for neural activity imaging
    • Akerboom, J. et al. Optimization of a GCaMP calcium indicator for neural activity imaging. J. Neurosci. 32, 13819-13840 (2012).
    • (2012) J. Neurosci. , vol.32 , pp. 13819-13840
    • Akerboom, J.1
  • 26
    • 84918781649 scopus 로고    scopus 로고
    • A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission
    • Wong, C. O. et al. A TRPV channel in Drosophila motor neurons regulates presynaptic resting Ca2+ levels, synapse growth, and synaptic transmission. Neuron 84, 764-777 (2014).
    • (2014) Neuron , vol.84 , pp. 764-777
    • Wong, C.O.1
  • 27
    • 84903182269 scopus 로고    scopus 로고
    • Expression of multiple transgenes from a single construct using viral 2A peptides in Drosophila
    • Daniels, R. W., Rossano, A. J., Macleod, G. T. & Ganetzky, B. Expression of multiple transgenes from a single construct using viral 2A peptides in Drosophila. PLoS ONE 9, e100637 (2014).
    • (2014) PLoS ONE , vol.9 , pp. e100637
    • Daniels, R.W.1    Rossano, A.J.2    Macleod, G.T.3    Ganetzky, B.4
  • 28
    • 84880427381 scopus 로고    scopus 로고
    • Ultrasensitive fluorescent proteins for imaging neuronal activity
    • Chen, T. W. et al. Ultrasensitive fluorescent proteins for imaging neuronal activity. Nature 499, 295-300 (2013).
    • (2013) Nature , vol.499 , pp. 295-300
    • Chen, T.W.1
  • 29
    • 84876451754 scopus 로고    scopus 로고
    • Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer
    • Roti, G. et al. Complementary genomic screens identify SERCA as a therapeutic target in NOTCH1 mutated cancer. Cancer Cell 23, 390-405 (2013).
    • (2013) Cancer Cell , vol.23 , pp. 390-405
    • Roti, G.1
  • 30
    • 0033230399 scopus 로고    scopus 로고
    • Ca2+-ATPase function is required for intracellular trafficking of the Notch receptor in Drosophila
    • Periz, G. & Fortini, M. E. Ca2+-ATPase function is required for intracellular trafficking of the Notch receptor in Drosophila. EMBO J. 18, 5983-5993 (1999).
    • (1999) EMBO J. , vol.18 , pp. 5983-5993
    • Periz, G.1    Fortini, M.E.2
  • 31
    • 80052606612 scopus 로고    scopus 로고
    • Calcineurin and its regulator Sra/DSCR1 are essential for sleep in Drosophila
    • Nakai, Y. et al. Calcineurin and its regulator Sra/DSCR1 are essential for sleep in Drosophila. J. Neurosci. 31, 12759-12766 (2011).
    • (2011) J. Neurosci. , vol.31 , pp. 12759-12766
    • Nakai, Y.1
  • 32
    • 33745970781 scopus 로고    scopus 로고
    • The calcineurin regulator sra plays an essential role in female meiosis in Drosophila
    • Takeo, S., Tsuda, M., Akahori, S., Matsuo, T. & Aigaki, T. The calcineurin regulator sra plays an essential role in female meiosis in Drosophila. Curr. Biol. 16, 1435-1440 (2006).
    • (2006) Curr. Biol. , vol.16 , pp. 1435-1440
    • Takeo, S.1    Tsuda, M.2    Akahori, S.3    Matsuo, T.4    Aigaki, T.5
  • 33
    • 79951962147 scopus 로고    scopus 로고
    • CREB and the CRTC co-activators: Sensors for hormonal and metabolic signals
    • Altarejos, J. Y. & Montminy, M. CREB and the CRTC co-activators: Sensors for hormonal and metabolic signals. Nature Rev. Mol. Cell Biol. 12, 141-151 (2011).
    • (2011) Nature Rev. Mol. Cell Biol. , vol.12 , pp. 141-151
    • Altarejos, J.Y.1    Montminy, M.2
  • 34
    • 42649140573 scopus 로고    scopus 로고
    • The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila
    • Wang, B. et al. The insulin-regulated CREB coactivator TORC promotes stress resistance in Drosophila. Cell Metab. 7, 434-444 (2008).
    • (2008) Cell Metab. , vol.7 , pp. 434-444
    • Wang, B.1
  • 35
    • 84872798743 scopus 로고    scopus 로고
    • Fasting launches CRTC to facilitate long-term memory formation in Drosophila
    • Hirano, Y. et al. Fasting launches CRTC to facilitate long-term memory formation in Drosophila. Science 339, 443-446 (2013).
    • (2013) Science , vol.339 , pp. 443-446
    • Hirano, Y.1
  • 36
    • 78650397479 scopus 로고    scopus 로고
    • Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection
    • Buchon, N., Broderick, N. A., Kuraishi, T. & Lemaitre, B. Drosophila EGFR pathway coordinates stem cell proliferation and gut remodeling following infection. BMC Biol. 8, 152 (2010).
    • (2010) BMC Biol. , vol.8 , pp. 152
    • Buchon, N.1    Broderick, N.A.2    Kuraishi, T.3    Lemaitre, B.4
  • 37
    • 79551610653 scopus 로고    scopus 로고
    • Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila
    • Hochmuth, C. E., Biteau, B., Bohmann, D. & Jasper, H. Redox regulation by Keap1 and Nrf2 controls intestinal stem cell proliferation in Drosophila. Cell Stem Cell 8, 188-199 (2011).
    • (2011) Cell Stem Cell , vol.8 , pp. 188-199
    • Hochmuth, C.E.1    Biteau, B.2    Bohmann, D.3    Jasper, H.4
  • 38
    • 24944498730 scopus 로고    scopus 로고
    • Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila
    • Wu, Q., Zhang, Y., Xu, J. & Shen, P. Regulation of hunger-driven behaviors by neural ribosomal S6 kinase in Drosophila. Proc. Natl Acad. Sci. USA 102, 13289-13294 (2005).
    • (2005) Proc. Natl Acad. Sci. USA , vol.102 , pp. 13289-13294
    • Wu, Q.1    Zhang, Y.2    Xu, J.3    Shen, P.4
  • 39
    • 79955133184 scopus 로고    scopus 로고
    • EGF signaling regulates the proliferation of intestinal stem cells in Drosophila
    • Biteau, B. & Jasper, H. EGF signaling regulates the proliferation of intestinal stem cells in Drosophila. Development 138, 1045-1055 (2011).
    • (2011) Development , vol.138 , pp. 1045-1055
    • Biteau, B.1    Jasper, H.2
  • 40
    • 84918835614 scopus 로고    scopus 로고
    • Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation
    • Wang, L., Zeng, X., Ryoo, H. D. & Jasper, H. Integration of UPRER and oxidative stress signaling in the control of intestinal stem cell proliferation. PLoS Genet. 10, e1004568 (2014).
    • (2014) PLoS Genet. , vol.10 , pp. e1004568
    • Wang, L.1    Zeng, X.2    Ryoo, H.D.3    Jasper, H.4
  • 41
    • 84930160218 scopus 로고    scopus 로고
    • Haemocytes control stem cell activity in the Drosophila intestine
    • Ayyaz, A., Li, H. & Jasper, H. Haemocytes control stem cell activity in the Drosophila intestine. Nature Cell Biol. 17, 736-748 (2015).
    • (2015) Nature Cell Biol. , vol.17 , pp. 736-748
    • Ayyaz, A.1    Li, H.2    Jasper, H.3
  • 42
    • 79952021183 scopus 로고    scopus 로고
    • Exciting times beyond the brain: Metabotropic glutamate receptors in peripheral and non-neural tissues
    • Julio-Pieper, M., Flor, P. J., Dinan, T. G. & Cryan, J. F. Exciting times beyond the brain: Metabotropic glutamate receptors in peripheral and non-neural tissues. Pharmacol. Rev. 63, 35-58 (2011).
    • (2011) Pharmacol. Rev. , vol.63 , pp. 35-58
    • Julio-Pieper, M.1    Flor, P.J.2    Dinan, T.G.3    Cryan, J.F.4
  • 43
    • 75149148563 scopus 로고    scopus 로고
    • Q's next: The diverse functions of glutamine in metabolism, cell biology and cancer
    • DeBerardinis, R. J. & Cheng, T. Q's next: The diverse functions of glutamine in metabolism, cell biology and cancer. Oncogene 29, 313-324 (2010).
    • (2010) Oncogene , vol.29 , pp. 313-324
    • DeBerardinis, R.J.1    Cheng, T.2
  • 44
    • 84892714390 scopus 로고    scopus 로고
    • PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan
    • Guo, L., Karpac, J., Tran, S. L. & Jasper, H. PGRP-SC2 promotes gut immune homeostasis to limit commensal dysbiosis and extend lifespan. Cell 156, 109-122 (2014).
    • (2014) Cell , vol.156 , pp. 109-122
    • Guo, L.1    Karpac, J.2    Tran, S.L.3    Jasper, H.4
  • 45
    • 34547148485 scopus 로고    scopus 로고
    • Protection of the glutamate pool concentration in enteric bacteria
    • Yan, D. Protection of the glutamate pool concentration in enteric bacteria. Proc. Natl Acad. Sci. USA 104, 9475-9480 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 9475-9480
    • Yan, D.1
  • 46
    • 52949093944 scopus 로고    scopus 로고
    • JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut
    • Biteau, B., Hochmuth, C. E. & Jasper, H. JNK activity in somatic stem cells causes loss of tissue homeostasis in the aging Drosophila gut. Cell Stem Cell 3, 442-455 (2008).
    • (2008) Cell Stem Cell , vol.3 , pp. 442-455
    • Biteau, B.1    Hochmuth, C.E.2    Jasper, H.3
  • 47
    • 54549104587 scopus 로고    scopus 로고
    • Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells
    • Lin, G., Xu, N. & Xi, R. Paracrine Wingless signalling controls self-renewal of Drosophila intestinal stem cells. Nature 455, 1119-1123 (2008).
    • (2008) Nature , vol.455 , pp. 1119-1123
    • Lin, G.1    Xu, N.2    Xi, R.3
  • 48
    • 79954997501 scopus 로고    scopus 로고
    • Development of the Drosophila entero-endocrine lineage and its specification by the Notch signaling pathway
    • Takashima, S. et al. Development of the Drosophila entero-endocrine lineage and its specification by the Notch signaling pathway. Dev. Biol. 353, 161-172 (2011).
    • (2011) Dev. Biol. , vol.353 , pp. 161-172
    • Takashima, S.1
  • 49
    • 34347207237 scopus 로고    scopus 로고
    • Prandiology of Drosophila and the CAFE assay
    • Ja, W. W. et al. Prandiology of Drosophila and the CAFE assay. Proc. Natl Acad. Sci. USA 104, 8253-8256 (2007).
    • (2007) Proc. Natl Acad. Sci. USA , vol.104 , pp. 8253-8256
    • Ja, W.W.1
  • 50
    • 72949117234 scopus 로고    scopus 로고
    • Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila
    • Grandison, R. C., Piper, M. D. & Partridge, L. Amino-acid imbalance explains extension of lifespan by dietary restriction in Drosophila. Nature 462, 1061-1064 (2009).
    • (2009) Nature , vol.462 , pp. 1061-1064
    • Grandison, R.C.1    Piper, M.D.2    Partridge, L.3
  • 51
    • 84879766950 scopus 로고    scopus 로고
    • Development and characterization of a chemically defined food for Drosophila
    • Lee, W. C. & Micchelli, C. A. Development and characterization of a chemically defined food for Drosophila. PLoS ONE 8, e67308 (2013).
    • (2013) PLoS ONE , vol.8 , pp. e67308
    • Lee, W.C.1    Micchelli, C.A.2
  • 52
    • 85001544012 scopus 로고    scopus 로고
    • Regulation of food intake by mechanosensory ion channels in enteric neurons
    • Olds, W. H. & Xu, T. Regulation of food intake by mechanosensory ion channels in enteric neurons. Elife 3, 04402 (2014).
    • (2014) Elife , vol.3 , pp. 04402
    • Olds, W.H.1    Xu, T.2
  • 53
    • 78650866455 scopus 로고    scopus 로고
    • Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis
    • Cognigni, P., Bailey, A. P. & Miguel-Aliaga, I. Enteric neurons and systemic signals couple nutritional and reproductive status with intestinal homeostasis. Cell Metab. 13, 92-104 (2011).
    • (2011) Cell Metab. , vol.13 , pp. 92-104
    • Cognigni, P.1    Bailey, A.P.2    Miguel-Aliaga, I.3
  • 54
    • 33644633961 scopus 로고    scopus 로고
    • Conditional mutations in SERCA, the Sarco-endoplasmic reticulum Ca2+-ATPase, alter heart rate and rhythmicity in Drosophila
    • Sanyal, S., Jennings, T., Dowse, H. & Ramaswami, M. Conditional mutations in SERCA, the Sarco-endoplasmic reticulum Ca2+-ATPase, alter heart rate and rhythmicity in Drosophila. J. Comp. Physiol. B 176, 253-263 (2006).
    • (2006) J. Comp. Physiol. B , vol.176 , pp. 253-263
    • Sanyal, S.1    Jennings, T.2    Dowse, H.3    Ramaswami, M.4
  • 55
    • 61749104447 scopus 로고    scopus 로고
    • Regulation of DUOX by the G? Q-phospholipase C?-Ca2+ pathway in Drosophila gut immunity
    • Ha, E. M. et al. Regulation of DUOX by the G? q-phospholipase C?-Ca2+ pathway in Drosophila gut immunity. Dev. Cell 16, 386-397 (2009).
    • (2009) Dev. Cell , vol.16 , pp. 386-397
    • Ha, E.M.1


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