-
1
-
-
84925437395
-
-
Ament SA, Szelinger S, Glusman G, Ashworth J, Hou L, Akula N, Shekhtman T, Badner JA, Brunkow ME, Mauldin DE, Stittrich AB, Rouleau K, Detera-Wadleigh SD, Nurnberger JI Jr, Edenberg HJ, Gershon ES, Schork N; Bipolar Genome Study, et al. (2015) Rare variants in neuronal excitability genes influence risk for bipolar disorder. Proc Natl Acad Sci U S A 112: 3576-3581. CrossRef Medline
-
Proc Natl Acad Sci U S A
-
-
Ament, S.A.1
Szelinger, S.2
Glusman, G.3
Ashworth, J.4
Hou, L.5
Akula, N.6
Shekhtman, T.7
Badner, J.A.8
Brunkow, M.E.9
Mauldin, D.E.10
Stittrich, A.B.11
Rouleau, K.12
Detera-Wadleigh, S.D.13
Nurnberger, J.I.14
Edenberg, H.J.15
Gershon, E.S.16
Schork, N.17
-
2
-
-
84860162767
-
-
Amiri A, Cho W, Zhou J, Birnbaum SG, Sinton CM, McKay RM, Parada LF (2012) Pten deletion in adult hippocampal neural stem/ progenitor cells causes cellular abnormalities and alters neurogenesis. J Neurosci 32: 5880-5890. CrossRef Medline
-
J Neurosci
-
-
Amiri, A.1
Cho, W.2
Zhou, J.3
Birnbaum, S.G.4
Sinton, C.M.5
McKay, R.M.6
Parada, L.F.7
-
4
-
-
0242300273
-
-
Brown JP, Couillard-Després S, Cooper-Kuhn CM, Winkler J, Aigner L, Kuhn HG (2003) Transient expression of doublecortin during adult neurogenesis. J Comp Neurol 467: 1-10. CrossRef Medline
-
J Comp Neurol
-
-
Brown, J.P.1
Couillard-Després, S.2
Cooper-Kuhn, C.M.3
Winkler, J.4
Aigner, L.5
Kuhn, H.G.6
-
5
-
-
0028364703
-
-
Cameron HA, Gould E (1994) Adult neurogenesis is regulated by adrenal steroids in the dentate gyrus. Neuroscience 61: 203-209. Medline
-
Neuroscience
-
-
Cameron, H.A.1
Gould, E.2
-
6
-
-
73949093011
-
-
Casamassima F, Huang J, Fava M, Sachs GS, Smoller JW, Cassano GB, Lattanzi L, Fagerness J, Stange JP, Perlis RH (2010) Phenotypic effects of a bipolar liability gene among individuals with major depressive disorder. Am J Med Genet B Neuropsychiatr Genet 153B: 303-309. CrossRef Medline
-
Am J Med Genet B Neuropsychiatr Genet
-
-
Casamassima, F.1
Huang, J.2
Fava, M.3
Sachs, G.S.4
Smoller, J.W.5
Cassano, G.B.6
Lattanzi, L.7
Fagerness, J.8
Stange, J.P.9
Perlis, R.H.10
-
8
-
-
0242332183
-
-
Chen WG, Chang Q, Lin Y, Meissner A, West AE, Griffith EC, Jaenisch R, Greenberg ME (2003) Derepression of BDNF transcription involves calcium-dependent phosphorylation of MeCP2. Science 302: 885-889. CrossRef Medline
-
Science
-
-
Chen, W.G.1
Chang, Q.2
Lin, Y.3
Meissner, A.4
West, A.E.5
Griffith, E.C.6
Jaenisch, R.7
Greenberg, M.E.8
-
9
-
-
84876296688
-
-
Cross-Disorder Group of the Psychiatric Genomics Consortium (2013) Identification of risk loci with shared effects on five major psychiatric disorders: a genome-wide analysis. Lancet 381: 1371-1379.
-
Lancet
-
-
-
11
-
-
77957900975
-
-
Dao DT, Mahon PB, Cai X, Kovacsics CE, Blackwell RA, Arad M, Shi J, Zandi PP, O’Donell P; Bipolar Genome Study (BiGS) Consortium, Knowles JA, Weissman MM, Coryell W, Scheftner WA, Lawson WB, Levinson DF, Thompson SM, Potash JB, Gould TD (2010) Mood disorder susceptibility gene CACNA1C modifies mood-related behaviors in mice and interacts with sex to influence behavior in mice and diagnosis in humans. Biol Psych 68: 801-810. CrossRef
-
Biol Psych
-
-
Dao, D.T.1
Mahon, P.B.2
Cai, X.3
Kovacsics, C.E.4
Blackwell, R.A.5
Arad, M.6
Shi, J.7
Zandi, P.P.8
O’Donell, P.9
Knowles, J.A.10
Weissman, M.M.11
Coryell, W.12
Scheftner, W.A.13
Lawson, W.B.14
Levinson, D.F.15
Thompson, S.M.16
Potash, J.B.17
Gould, T.D.18
-
12
-
-
84867628671
-
-
De Jesus-Cortés H, Xu P, Drawbridge J, Estill SJ, Huntington P, Tran S, Britt J, Tesla R, Morlock L, Naidoo J, Melito LM, Wang G, Williams NS, Ready JM, McKnight SL, Pieper AA (2012) Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease. Proc Natl Acad Sci U S A 109: 17010-17015. CrossRef Medline
-
Proc Natl Acad Sci U S A
-
-
De Jesus-Cortés, H.1
Xu, P.2
Drawbridge, J.3
Estill, S.J.4
Huntington, P.5
Tran, S.6
Britt, J.7
Tesla, R.8
Morlock, L.9
Naidoo, J.10
Melito, L.M.11
Wang, G.12
Williams, N.S.13
Ready, J.M.14
McKnight, S.L.15
Pieper, A.A.16
-
13
-
-
84978993731
-
-
De Jesus Cortés H, Miller AD, Britt JK, DeMarco AJ, De Jesus-Cortes M, Steubing E, Naidoo J, Wasquez-Rosa W, Morlock L, Williams NS, Ready JM, Narayanan NS, Pieper AA (2015) Protective efficacy of P7C3-S243 in the 6-hydroxydopamine model of Parkinson’s disease. Parkinsons Dis 1: 15010.
-
Parkinsons Dis
-
-
De Jesus Cortés, H.1
Miller, A.D.2
Britt, J.K.3
DeMarco, A.J.4
De Jesus-Cortes, M.5
Steubing, E.6
Naidoo, J.7
Wasquez-Rosa, W.8
Morlock, L.9
Williams, N.S.10
Ready, J.M.11
Narayanan, N.S.12
Pieper, A.A.13
-
14
-
-
2442477425
-
-
Deisseroth K, Singla S, Toda H, Monje M, Palmer TD, Malenka RC (2004) Excitation-neurogenesis coupling in adult neural stem/progenitor cells. Neuron 42: 535-552. Medline
-
Neuron
-
-
Deisseroth, K.1
Singla, S.2
Toda, H.3
Monje, M.4
Palmer, T.D.5
Malenka, R.C.6
-
16
-
-
84919372230
-
-
Dutca LM, Stasheff SF, Hedberg-Buenz A, Rudd DS, Batra N, Blodi FR, Yorek MS, Yin T, Shankar M, Herlein JA, Naidoo J, Morlock L, Williams N, Kardon RH, Anderson MG, Pieper AA, Harper MM (2014) Early detection of subclinical visual damage after blastmediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243. Invest Ophthalmol Vis Sci 55: 8330-41. CrossRef Medline
-
Invest Ophthalmol Vis Sci
-
-
Dutca, L.M.1
Stasheff, S.F.2
Hedberg-Buenz, A.3
Rudd, D.S.4
Batra, N.5
Blodi, F.R.6
Yorek, M.S.7
Yin, T.8
Shankar, M.9
Herlein, J.A.10
Naidoo, J.11
Morlock, L.12
Williams, N.13
Kardon, R.H.14
Anderson, M.G.15
Pieper, A.A.16
Harper, M.M.17
-
17
-
-
50449089356
-
-
Ferreira MA, O’Donovan MC, Meng YA, Jones IR, Ruderfer DM, Jones L, Fan J, Kirov G, Perlis RH, Green EK, Smoller JW, Grozeva D, Stone J, Nikolov I, Chambert K, Hamshere ML, Nimgaonkar VL, Moskvina V, Thase ME, Caesar S, et al. (2008) Collaborative genome-wide association analysis supports a role for ANK3 and CACNA1C in bipolar disorder. Nat Genet 40: 1056-1058. CrossRef Medline
-
Nat Genet
-
-
Ferreira, M.A.1
O’Donovan, M.C.2
Meng, Y.A.3
Jones, I.R.4
Ruderfer, D.M.5
Jones, L.6
Fan, J.7
Kirov, G.8
Perlis, R.H.9
Green, E.K.10
Smoller, J.W.11
Grozeva, D.12
Stone, J.13
Nikolov, I.14
Chambert, K.15
Hamshere, M.L.16
Nimgaonkar, V.L.17
Moskvina, V.18
Thase, M.E.19
Caesar, S.20
more..
-
18
-
-
84883149417
-
-
Fitzsimons CP, van Hooijdonk LW, Schouten M, Zalachoras I, Brinks V, Zheng T, Schouten TG, Saaltink DJ, Dijkmans T, Steindler DA, Verhaagen J, Verbeek FJ, Lucassen PJ, de Kloet ER, Meijer OC, Karst H, Joels M, Oitzl MS, Vreugdenhil E (2013) Knockdown of the glucocorticoid receptor alters functional integration of newborn neurons in the adult hippocampus and impairs fear-motivated behavior. Mol Psychiatry 18: 993-1005. CrossRef Medline
-
Mol Psychiatry
-
-
Fitzsimons, C.P.1
van Hooijdonk, L.W.2
Schouten, M.3
Zalachoras, I.4
Brinks, V.5
Zheng, T.6
Schouten, T.G.7
Saaltink, D.J.8
Dijkmans, T.9
Steindler, D.A.10
Verhaagen, J.11
Verbeek, F.J.12
Lucassen, P.J.13
de Kloet, E.R.14
Meijer, O.C.15
Karst, H.16
Joels, M.17
Oitzl, M.S.18
Vreugdenhil, E.19
-
20
-
-
78650325317
-
-
Giordano TP, Tropea TF, Satpute SS, Sinnegger-Brauns MJ, Striessnig J, Kosofsky BE, Rajadhyaksha AM (2010) Molecular switch from L-type Cav1.3 to Cav1.2 Ca2+ channel signaling underlies long-term psychostimulant-induced behavioral and molecular plasticity. J Neurosci 30: 17051-17062. CrossRef
-
J Neurosci
-
-
Giordano, T.P.1
Tropea, T.F.2
Satpute, S.S.3
Sinnegger-Brauns, M.J.4
Striessnig, J.5
Kosofsky, B.E.6
Rajadhyaksha, A.M.7
-
21
-
-
77954510735
-
-
Green EK, Grozeva D, Jones I, Jones L, Kirov G, Caesar S, Gordon-Smith K, Fraser C, Forty L, Russell E, Hamshere ML, Moskvina V, Nikolov I, Farmer A, McGuffin P; Wellcome Trust Case Control Consortium, Holmans PA, Owen MJ, O’Donovan MC, Craddock N (2010) The bipolar disorder risk allele at CACNA1C also confers risk of recurrent major depression and of schizophrenia. Mol Psychiatry 15: 1016-1022. CrossRef Medline
-
Mol Psychiatry
-
-
Green, E.K.1
Grozeva, D.2
Jones, I.3
Jones, L.4
Kirov, G.5
Caesar, S.6
Gordon-Smith, K.7
Fraser, C.8
Forty, L.9
Russell, E.10
Hamshere, M.L.11
Moskvina, V.12
Nikolov, I.13
Farmer, A.14
McGuffin, P.15
Holmans, P.A.16
Owen, M.J.17
O’Donovan, M.C.18
Craddock, N.19
-
22
-
-
84888296163
-
-
Green EK,Hamshere M, Forty L, Gordon-Smith K, Fraser C, Russell E, Grozeva D, Kirov G, Holmans P, Moran JL, Purcell S, Sklar P, Owen MJ, O’Donovan MC, Jones L, Jones IR, Craddock N (2013) Replication of bipolar disorder susceptibility alleles and identification of two novel genome-wide significant associations in a new bipolar disorder case-control sample. Mol Psychiatry 18: 1302-1307. CrossRef
-
Mol Psychiatry
-
-
Green, E.K.1
Hamshere, M.2
Forty, L.3
Gordon-Smith, K.4
Fraser, C.5
Russell, E.6
Grozeva, D.7
Kirov, G.8
Holmans, P.9
Moran, J.L.10
Purcell, S.11
Sklar, P.12
Owen, M.J.13
O’Donovan, M.C.14
Jones, L.15
Jones, I.R.16
Craddock, N.17
-
23
-
-
85043115148
-
-
Schizophrenia Psychiatric Genome-wide Association Study Consortium; Wellcome Trust Case Control Consortium+; Wellcome Trust Case Control Consortium
-
Hamshere ML, Walters JT, Smith R, Richards AL, Green E, Grozeva D, Jones I, Forty L, Jones L, Gordon-Smith K, Riley B, O’Neill FA, Kendler KS, Sklar P, Purcel S, Kranz J; Schizophrenia Psychiatric Genome-wide Association Study Consortium; Wellcome Trust Case Control Consortium+; Wellcome Trust Case Control Consortium
-
-
-
Hamshere, M.L.1
Walters, J.T.2
Smith, R.3
Richards, A.L.4
Green, E.5
Grozeva, D.6
Jones, I.7
Forty, L.8
Jones, L.9
Gordon-Smith, K.10
Riley, B.11
O’Neill, F.A.12
Kendler, K.S.13
Sklar, P.14
Purcel, S.15
Kranz, J.16
-
24
-
-
84878220679
-
-
Morris D, Gill M, Holmans P, Craddock N, Corvin A, Owen MJ, et al. (2013) Genome-wide significant associations in schizophrenia to ITIH3/4, CACNA1C and SDCCAG8, and extensive replication of associations reported by the Schizophrenia PGC. Mol Psychiatry 18: 708-712. CrossRef
-
Mol Psychiatry
-
-
Morris, D.1
Gill, M.2
Holmans, P.3
Craddock, N.4
Corvin, A.5
Owen, M.J.6
-
25
-
-
84947227793
-
-
Heyes S, Pratt WS, Rees E, Dahimene S, Ferron L, Owen MJ, Dolphin AC (2015) Genetic disruption of voltage-gated calcium channels in psychiatric and neurological disorders. Prog Neurobiol 134: 36-54.
-
Prog Neurobiol
-
-
Heyes, S.1
Pratt, W.S.2
Rees, E.3
Dahimene, S.4
Ferron, L.5
Owen, M.J.6
Dolphin, A.C.7
-
26
-
-
84887562180
-
-
Jolly LA, Homan CC, Jacob R, Barry S, Gecz J (2013) The UPF3B gene, implicated in intellectual disability, autism and ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth. Hum Mol Genet 22: 4673-87. CrossRef Medline
-
Hum Mol Genet
-
-
Jolly, L.A.1
Homan, C.C.2
Jacob, R.3
Barry, S.4
Gecz, J.5
-
27
-
-
84908389399
-
-
Kemp SW, Szynkaruk M, Stanoulis KN, Wood MD, Liu EH, Willand MP, Morlock L, Naidoo J, Williams NS, Ready JM, Mangano TJ, Beggs S, Salter MW, Gordon T, Pieper AA, Borschel GH (2015) Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury. Neuroscience 284: 202-216. CrossRef Medline
-
Neuroscience
-
-
Kemp, S.W.1
Szynkaruk, M.2
Stanoulis, K.N.3
Wood, M.D.4
Liu, E.H.5
Willand, M.P.6
Morlock, L.7
Naidoo, J.8
Williams, N.S.9
Ready, J.M.10
Mangano, T.J.11
Beggs, S.12
Salter, M.W.13
Gordon, T.14
Pieper, A.A.15
Borschel, G.H.16
-
28
-
-
83755219394
-
-
Knight HM, Walker R, James R, Porteous DJ, Muir WJ, Blackwood DH, Pickard BS (2012) GRIK4/KA1 protein expression in human brain and correlation with bipolar disorder risk variant status. Am J Med Genet B Neuropsychiatr Genet 159B: 21-29. CrossRef Medline
-
Am J Med Genet B Neuropsychiatr Genet
-
-
Knight, H.M.1
Walker, R.2
James, R.3
Porteous, D.J.4
Muir, W.J.5
Blackwood, D.H.6
Pickard, B.S.7
-
29
-
-
84894458380
-
-
Kobayashi M, Nakatani T, Koda T, Matsumoto K, Ozaki R, Mochida N, Takao K, Miyakawa T, Matsuoka I (2014) Absence of BRINP1 in mice causes increase of hippocampal neurogenesis and behavioral alterations relevant to human psychiatric disorders. Mol Brain 7: 12. CrossRef Medline
-
Mol Brain
-
-
Kobayashi, M.1
Nakatani, T.2
Koda, T.3
Matsumoto, K.4
Ozaki, R.5
Mochida, N.6
Takao, K.7
Miyakawa, T.8
Matsuoka, I.9
-
31
-
-
77954117096
-
-
Langwieser N, Christel CH, Kleppisch T, Hofmann F, Wotjak CT, Moosmang S (2010) Homeostatic switch in hebbian plasticity and fear learning after sustained loss of Cav1.2 calcium channels. J Neurosci 30: 8367-8375. CrossRef Medline
-
J Neurosci
-
-
Langwieser, N.1
Christel, C.H.2
Kleppisch, T.3
Hofmann, F.4
Wotjak, C.T.5
Moosmang, S.6
-
32
-
-
79955473843
-
-
Lee MT, Chen CH, Lee CS, Chen CC, Chong MY, Ouyang WC, Chiu NY, Chuo LJ, Chen CY, Tan HK, Lane HY, Chang TJ, Lin CH, Jou SH, Hou YM, Feng J, Lai TJ, Tung CL, Chen TJ, Chang CJ, et al. (2011) Genome-wide association study of bipolar I disorder in the Han Chinese population. Mol Psychiatry 16: 548-556. CrossRef Medline
-
Mol Psychiatry
-
-
Lee, M.T.1
Chen, C.H.2
Lee, C.S.3
Chen, C.C.4
Chong, M.Y.5
Ouyang, W.C.6
Chiu, N.Y.7
Chuo, L.J.8
Chen, C.Y.9
Tan, H.K.10
Lane, H.Y.11
Chang, T.J.12
Lin, C.H.13
Jou, S.H.14
Hou, Y.M.15
Feng, J.16
Lai, T.J.17
Tung, C.L.18
Chen, T.J.19
Chang, C.J.20
more..
-
33
-
-
84867897720
-
-
Lee AS, Ra S, Rajadhyaksha AM, Britt JK, De Jesus-Cortes H, Gonzales KL, Lee A, Moosmang S, Hofman F, Pieper AA, Rajadhyaksha AM (2012) Forebrain elimination of cacna1c mediates anxiety-like behavior in mice. Mol Psych 17: 1054-1055. CrossRef Medline
-
Mol Psych
-
-
Lee, A.S.1
Ra, S.2
Rajadhyaksha, A.M.3
Britt, J.K.4
De Jesus-Cortes, H.5
Gonzales, K.L.6
Lee, A.7
Moosmang, S.8
Hofman, F.9
Pieper, A.A.10
Rajadhyaksha, A.M.11
-
34
-
-
68349160475
-
-
Le Strat Y, Ramoz N, Gorwood P (2009) The role of genes involved in neuroplasticity and neurogenesis in the observation of a geneenvironment interaction (GxE) in schizophrenia. Curr Mol Med 9: 506-518. Medline
-
Curr Mol Med
-
-
Le Strat, Y.1
Ramoz, N.2
Gorwood, P.3
-
35
-
-
79551705492
-
-
MacMillan KS, Naidoo J, Liang J, Melito L, Williams NS, Morlock L, Huntington PJ, Estill SJ, Longgood J, Becker GL, McKnight SL, Pieper AA, De Brabander JK, Ready JM (2011) Development of proneurogenic, neuroprotective small molecules. J Am Chem Soc 133: 1428-1437. CrossRef Medline
-
J Am Chem Soc
-
-
MacMillan, K.S.1
Naidoo, J.2
Liang, J.3
Melito, L.4
Williams, N.S.5
Morlock, L.6
Huntington, P.J.7
Estill, S.J.8
Longgood, J.9
Becker, G.L.10
McKnight, S.L.11
Pieper, A.A.12
De Brabander, J.K.13
Ready, J.M.14
-
36
-
-
84947866310
-
-
Marschallinger J, Sah A, Schmuckermair C, Unger M, Rotheneichner P, Kharitonova M, Waclawiczek A, Gerner P, Jaksch-Bogensperger H, Berger S, Striessnig J, Singewald N, Couillard-Despres S, Aigner L (2015) The L-type calcium channel Cav1.3 is required for proper hippocampal neurogenesis and cognitive functions. Cell Calcium 58: 606-616. CrossRef Medline
-
Cell Calcium
-
-
Marschallinger, J.1
Sah, A.2
Schmuckermair, C.3
Unger, M.4
Rotheneichner, P.5
Kharitonova, M.6
Waclawiczek, A.7
Gerner, P.8
Jaksch-Bogensperger, H.9
Berger, S.10
Striessnig, J.11
Singewald, N.12
Couillard-Despres, S.13
Aigner, L.14
-
37
-
-
27344432023
-
-
Moosmang S, Haider N, Klugbauer N, Adelsberger H, Langwieser N, Müller J, Stiess M, Marais E, Schulla V, Lacinova L, Goebbels S, Nave KA, Storm DR, Hofmann F, Kleppisch T (2005) Role of hippocampal Cav1.2 Ca2+ channels in NMDA receptorindependent synaptic plasticity and spatial memory. J Neurosci 25: 9883-9892. CrossRef
-
J Neurosci
-
-
Moosmang, S.1
Haider, N.2
Klugbauer, N.3
Adelsberger, H.4
Langwieser, N.5
Müller, J.6
Stiess, M.7
Marais, E.8
Schulla, V.9
Lacinova, L.10
Goebbels, S.11
Nave, K.A.12
Storm, D.R.13
Hofmann, F.14
Kleppisch, T.15
-
38
-
-
84900318312
-
-
Naidoo J, De Jesus-Cortes H, Huntington P, Estill S, Morlock LK, Starwalt R, Mangano TJ, Williams NS, Pieper AA, Ready JM (2014) Discovery of a neuroprotective chemical, (S)-N-(3-(3,6-dibromo-9H-carbazol-9-yl)-2-fluoropropyl)-6-methoxypyridin-2-amine[(-)-P7C3-S243], with improved druglike properties. J Med Chem 57: 3746-54. CrossRef
-
J Med Chem
-
-
Naidoo, J.1
De Jesus-Cortes, H.2
Huntington, P.3
Estill, S.4
Morlock, L.K.5
Starwalt, R.6
Mangano, T.J.7
Williams, N.S.8
Pieper, A.A.9
Ready, J.M.10
-
39
-
-
84902204761
-
-
Nurnberger JI Jr, Koller DL, Jung J, Edenberg HJ, Foroud T, Guella I, Vawter MP, Kelsoe JR (2014) Identification of pathways for bipolar disorder: a meta-analysis. JAMA Psychiatry 71: 657-664. CrossRef Medline
-
JAMA Psychiatry
-
-
Nurnberger Jr, J.I.1
Koller, D.L.2
Jung, J.3
Edenberg, H.J.4
Foroud, T.5
Guella, I.6
Vawter, M.P.7
Kelsoe, J.R.8
-
40
-
-
75649110777
-
-
Nyegaard M, Demontis D, Foldager L, Hedemand A, Flint TJ, Sørensen KM, Andersen PS, Nordentoft M, Werge T, Pedersen CB, Hougaard DM, Mortensen PB, Mors O, Børglum AD (2010) CACNA1C (rs1006737) is associated with schizophrenia. Mol Psychiatry 15: 119-121. CrossRef Medline
-
Mol Psychiatry
-
-
Nyegaard, M.1
Demontis, D.2
Foldager, L.3
Hedemand, A.4
Flint, T.J.5
Sørensen, K.M.6
Andersen, P.S.7
Nordentoft, M.8
Werge, T.9
Pedersen, C.B.10
Hougaard, D.M.11
Mortensen, P.B.12
Mors, O.13
Børglum, A.D.14
-
41
-
-
84874793864
-
-
Ohira K, Kobayashi K, Toyama K, Nakamura HK, Shoji H, Takao K, Takeuchi R, Yamaguchi S, Kataoka M, Otsuka S, Takahashi M, Miyakawa T (2013) Synaptosomal-associated protein 25 mutation induces immaturity of the dentate granule cells of adult mice. Mol Brain 6: 12. CrossRef Medline
-
Mol Brain
-
-
Ohira, K.1
Kobayashi, K.2
Toyama, K.3
Nakamura, H.K.4
Shoji, H.5
Takao, K.6
Takeuchi, R.7
Yamaguchi, S.8
Kataoka, M.9
Otsuka, S.10
Takahashi, M.11
Miyakawa, T.12
-
43
-
-
80053446248
-
-
Pickard B (2011) Progress in defining the biological causes of schizophrenia. Expert Rev Mol Med 13: e25. CrossRef Medline
-
Expert Rev Mol Med
-
-
Pickard, B.1
-
44
-
-
25444529227
-
-
Pieper AA, Wu X, Han TW, Estill SJ, Dang Q, Wu LC, Reece-Fincanon S, Dudley CA, Richardson JA, Brat DJ, McKnight SL (2005) The neuronal PAS domain protein 3 transcription factor controls FGFmediated adult hippocampal neurogenesis in mice. Proc Natl Acad Sci U S A 102: 14052-14057. CrossRef Medline
-
Proc Natl Acad Sci U S A
-
-
Pieper, A.A.1
Wu, X.2
Han, T.W.3
Estill, S.J.4
Dang, Q.5
Wu, L.C.6
Reece-Fincanon, S.7
Dudley, C.A.8
Richardson, J.A.9
Brat, D.J.10
McKnight, S.L.11
-
45
-
-
77954266958
-
-
Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM, Becker GL, Huntington P, Goldman SE, Shen CH, Capota M, Britt JK, Kotti T, Ure K, Brat DJ, Williams NS, MacMillan KS, Naidoo J, Melito L, Hsieh J, et al. (2010) Discovery of a proneurogenic, neuroprotective chemical. Cell 142: 39-51. CrossRef Medline
-
Cell
-
-
Pieper, A.A.1
Xie, S.2
Capota, E.3
Estill, S.J.4
Zhong, J.5
Long, J.M.6
Becker, G.L.7
Huntington, P.8
Goldman, S.E.9
Shen, C.H.10
Capota, M.11
Britt, J.K.12
Kotti, T.13
Ure, K.14
Brat, D.J.15
Williams, N.S.16
MacMillan, K.S.17
Naidoo, J.18
Melito, L.19
Hsieh, J.20
more..
-
47
-
-
80053385384
-
-
Psychiatric GWAS Consortium Bipolar Disorder Working Group (2011) Large scale genome-wide association analysis of bipolar disorder identifies a new susceptibility locus near ODZ4. Nat Genet 43: 977-983.
-
Nat Genet
-
-
-
49
-
-
84885020424
-
-
Ripke S, O’Dushlaine C, Chambert K, Moran JL, Kähler AK, Akterin S, Bergen SE, Collins AL, Crowley JJ, Fromer M, Kim Y, Lee SH, Magnusson PK, Sanchez N, Stahl EA, Williams S, Wray NR, Xia K, Bettella F, Borglum AD, et al.; Multicenter Genetic Studies of Schizophrenia Consortium; Psychosis Endophenotypes International Consortium; Wellcome Trust Case Control Consortium 2 (2013) Genome-wide association analysis identifies 13 new risk loci for schizophrenia. Nat Genet 45: 1150-1159. CrossRef
-
Nat Genet
-
-
Ripke, S.1
O’Dushlaine, C.2
Chambert, K.3
Moran, J.L.4
Kähler, A.K.5
Akterin, S.6
Bergen, S.E.7
Collins, A.L.8
Crowley, J.J.9
Fromer, M.10
Kim, Y.11
Lee, S.H.12
Magnusson, P.K.13
Sanchez, N.14
Stahl, E.A.15
Williams, S.16
Wray, N.R.17
Xia, K.18
Bettella, F.19
Borglum, A.D.20
more..
-
50
-
-
80053029984
-
-
Schierberl K, Hao J, Tropea TF, Ra S, Giordano TP, Xu Q, Garraway SM, Hofmann F, Moosmang S, Striessnig J, Inturrisi CE, Rajadhyaksha AM (2011) Cav1.2 L-type Ca2+ channels mediate cocaine-induced GluA1 trafficking in the nucleus accumbens, a long-term adaptation dependent on ventral tegmental area Ca(v)1.3 channels. J Neurosci 31: 13562-13575. CrossRef
-
J Neurosci
-
-
Schierberl, K.1
Hao, J.2
Tropea, T.F.3
Ra, S.4
Giordano, T.P.5
Xu, Q.6
Garraway, S.M.7
Hofmann, F.8
Moosmang, S.9
Striessnig, J.10
Inturrisi, C.E.11
Rajadhyaksha, A.M.12
-
51
-
-
84904804929
-
-
Schizophrenia Working Group of the Psychiatric Genomics Consortium (2014) Biological insights from the 108 schizophreniaassociated genetic loci. Nature 511: 421-427.
-
Nature
-
-
-
52
-
-
84897962568
-
-
Schreiber R, Newman-Tancredi A (2014) Improving cognition in schizophrenia with antipsychotics that elicit neurogenesis through 5-HT(1A) receptor activation. Neurobiol Learn Mem 110: 72-80. CrossRef Medline
-
Neurobiol Learn Mem
-
-
Schreiber, R.1
Newman-Tancredi, A.2
-
53
-
-
84924162021
-
-
Serafini G, Hayley S, Pompili M, Dwivedi Y, Brahmachari G, Girardi P, Amore M (2014) Hippocampal neurogenesis, neurotrophic factors and depression: possible therapeutic targets? CNS Neurol Disord Drug Targets 13: 1708-21. Medline
-
CNS Neurol Disord Drug Targets
-
-
Serafini, G.1
Hayley, S.2
Pompili, M.3
Dwivedi, Y.4
Brahmachari, G.5
Girardi, P.6
Amore, M.7
-
54
-
-
84881112822
-
-
Singh C, Bortolato M, Bali N, Godar SC, Scott AL, Chen K, Thompson RF, Shih JC (2013) Cognitive abnormalities and hippocampal alterations in monoamine oxidase A and B knockout mice. Proc Natl Acad Sci U S A 110: 12816-12821. CrossRef Medline
-
Proc Natl Acad Sci U S A
-
-
Singh, C.1
Bortolato, M.2
Bali, N.3
Godar, S.C.4
Scott, A.L.5
Chen, K.6
Thompson, R.F.7
Shih, J.C.8
-
55
-
-
43949118134
-
-
Sklar P, Smoller JW, Fan J, Ferreira MA, Perlis RH, Chambert K, Nimgaonkar VL, McQueen MB, Faraone SV, Kirby A, de Bakker PI, Ogdie MN, Thase ME, Sachs GS, Todd-Brown K, Gabriel SB, Sougnez C, Gates C, Blumenstiel B, Defelice M, et al. (2008) Whole-genome association study of bipolar disorder. Mol Psychiatry 13: 558-569. CrossRef Medline
-
Mol Psychiatry
-
-
Sklar, P.1
Smoller, J.W.2
Fan, J.3
Ferreira, M.A.4
Perlis, R.H.5
Chambert, K.6
Nimgaonkar, V.L.7
McQueen, M.B.8
Faraone, S.V.9
Kirby, A.10
de Bakker, P.I.11
Ogdie, M.N.12
Thase, M.E.13
Sachs, G.S.14
Todd-Brown, K.15
Gabriel, S.B.16
Sougnez, C.17
Gates, C.18
Blumenstiel, B.19
Defelice, M.20
more..
-
56
-
-
84919458532
-
-
Stanco A, Pla R, Vogt D, Chen Y, Mandal S, Walker J, Hunt RF, Lindtner S, Erdman CA, Pieper AA, Hamilton SP, Xu D, Baraban SC, Rubenstein JL (2014) NPAS1 represses the generation of specific subtypes of cortical interneurons. Neuron 84: 940-53. CrossRef Medline
-
Neuron
-
-
Stanco, A.1
Pla, R.2
Vogt, D.3
Chen, Y.4
Mandal, S.5
Walker, J.6
Hunt, R.F.7
Lindtner, S.8
Erdman, C.A.9
Pieper, A.A.10
Hamilton, S.P.11
Xu, D.12
Baraban, S.C.13
Rubenstein, J.L.14
-
57
-
-
84891638562
-
-
Takamura N, Nakagawa S, Masuda T, Boku S, Kato A, Song N, An Y, Kitaichi Y, Inoue T, Koyama T, Kusumi I (2014) The effect of dopamine on adult hippocampal neurogenesis. Prog Neuropsychopharmacol Biol Psychiatry 50: 116-24. CrossRef Medline
-
Prog Neuropsychopharmacol Biol Psychiatry
-
-
Takamura, N.1
Nakagawa, S.2
Masuda, T.3
Boku, S.4
Kato, A.5
Song, N.6
An, Y.7
Kitaichi, Y.8
Inoue, T.9
Koyama, T.10
Kusumi, I.11
-
59
-
-
0037204070
-
-
Tao X, West AE, Chen WG, Corfas G, Greenberg ME (2002) A calcium-responsive transcription factor, CaRF, that regulates neuronal activity-dependent expression of BDNF. Neuron 33: 383-395. Medline
-
Neuron
-
-
Tao, X.1
West, A.E.2
Chen, W.G.3
Corfas, G.4
Greenberg, M.E.5
-
60
-
-
63849239275
-
-
Tao J, Hu K, Chang Q, Wu H, Sherman NE, Martinowich K, Klose RJ, Schanen C, Jaenisch R, Wang W, Sun YE (2009) Phosphorylation of MeCP2 at Serine 80 regulates its chromatin association and neurological function. Proc Natl Acad Sci U S A 106: 4882-4887. CrossRef Medline
-
Proc Natl Acad Sci U S A
-
-
Tao, J.1
Hu, K.2
Chang, Q.3
Wu, H.4
Sherman, N.E.5
Martinowich, K.6
Klose, R.J.7
Schanen, C.8
Jaenisch, R.9
Wang, W.10
Sun, Y.E.11
-
61
-
-
84931057450
-
-
Teh DB, Ishizuka H, Yawo H (2014) Regulation of later neurogenic stages of adult-derived neural stem/progenitor cells by L-type Ca channels. Dev Growth Differ 56: 583-594. CrossRef Medline
-
Dev Growth Differ
-
-
Teh, D.B.1
Ishizuka, H.2
Yawo, H.3
-
62
-
-
84867639321
-
-
Tesla R, Wolf HP, Xu P, Drawbridge J, Estill SJ, Huntington P, McDaniel L, Knobbe W, Burket A, Tran S, Starwalt R, Morlock L, Naidoo J, Williams NS, Ready JM, McKnight SL, Pieper AA (2012) Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 109: 17016-21. CrossRef
-
Proc Natl Acad Sci U S A
-
-
Tesla, R.1
Wolf, H.P.2
Xu, P.3
Drawbridge, J.4
Estill, S.J.5
Huntington, P.6
McDaniel, L.7
Knobbe, W.8
Burket, A.9
Tran, S.10
Starwalt, R.11
Morlock, L.12
Naidoo, J.13
Williams, N.S.14
Ready, J.M.15
McKnight, S.L.16
Pieper, A.A.17
-
63
-
-
84926158983
-
-
Walker AK, Rivera PD, Wang Q, Chuang JC, Tran S, Osborne-Lawrence S, Estill SJ, Starwalt R, Huntington P, Morlock L, Naidoo J, Williams NS, Ready JM, Eisch AJ, Pieper AA, Zigman JM (2015) The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis. Mol Psychiatry 20: 500-508. CrossRef
-
Mol Psychiatry
-
-
Walker, A.K.1
Rivera, P.D.2
Wang, Q.3
Chuang, J.C.4
Tran, S.5
Osborne-Lawrence, S.6
Estill, S.J.7
Starwalt, R.8
Huntington, P.9
Morlock, L.10
Naidoo, J.11
Williams, N.S.12
Ready, J.M.13
Eisch, A.J.14
Pieper, A.A.15
Zigman, J.M.16
-
64
-
-
84907390733
-
-
Wang G, Han T, Nijhawan D, Theodoropoulos P, Naidoo J, Yadavalli S, Mirzaei H, Pieper AA, Ready JM, McKnight SL (2014) P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell 158: 1324-1334. CrossRef Medline
-
Cell
-
-
Wang, G.1
Han, T.2
Nijhawan, D.3
Theodoropoulos, P.4
Naidoo, J.5
Yadavalli, S.6
Mirzaei, H.7
Pieper, A.A.8
Ready, J.M.9
McKnight, S.L.10
-
65
-
-
78650241063
-
-
Wessa M, Linke J, Witt SH, Nieratschker V, Esslinger C, Kirsch P, Grimm O, Hennerici MG, Gass A, King AV, Rietschel M (2010) The CACNA1C risk variant for bipolar disorder influences limbic activity. Mol Psychiatry 15: 1126-1127. CrossRef Medline
-
Mol Psychiatry
-
-
Wessa, M.1
Linke, J.2
Witt, S.H.3
Nieratschker, V.4
Esslinger, C.5
Kirsch, P.6
Grimm, O.7
Hennerici, M.G.8
Gass, A.9
King, A.V.10
Rietschel, M.11
-
66
-
-
85043109641
-
-
(Lewin GR, Carter BD, eds). Berlin, Heidelberg: Springer Berlin Heidelberg
-
West AE, Pruunsild P, Timmusk T (2014) Neurotrophic factors: handbook of experimental pharmacology, Vol220, (Lewin GR, Carter BD, eds). Berlin, Heidelberg: Springer Berlin Heidelberg.
-
(2014)
Neurotrophic factors: Handbook of experimental pharmacology, Vol220
-
-
West, A.E.1
Pruunsild, P.2
Timmusk, T.3
-
67
-
-
38649118171
-
-
White JA, McKinney BC, John MC, Powers PA, Kamp TJ, Murphy GG (2008) Conditional forebrain deletion of the L-type calcium channel CAv1.2 disrupts remote spatial memories in mice. Learn Mem 15: 1-5. CrossRef Medline
-
Learn Mem
-
-
White, J.A.1
McKinney, B.C.2
John, M.C.3
Powers, P.A.4
Kamp, T.J.5
Murphy, G.G.6
-
68
-
-
84875375493
-
-
Wu Q, Li Y, Xiao B (2013) DISC1-related signaling pathways in adult neurogenesis of the hippocampus. Gene 518: 223-230. CrossRef Medline
-
Gene
-
-
Wu, Q.1
Li, Y.2
Xiao, B.3
-
69
-
-
84907413877
-
-
Yin TC, Britt JK, De Jesus-Cortés H, Lu Y, Genova RM, Khan MZ, Voorhees JR, Shao J, Katzman AC, Huntington PJ, Wassink C, McDaniel L, Newell EA, Dutca LM, Naidoo J, Cui H, Bassuk AG, Harper MM, McKnight SL, Ready JM, Pieper AA (2014) P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury. Cell Rep 8: 1731-1740. CrossRef
-
Cell Rep
-
-
Yin, T.C.1
Britt, J.K.2
De Jesus-Cortés, H.3
Lu, Y.4
Genova, R.M.5
Khan, M.Z.6
Voorhees, J.R.7
Shao, J.8
Katzman, A.C.9
Huntington, P.J.10
Wassink, C.11
McDaniel, L.12
Newell, E.A.13
Dutca, L.M.14
Naidoo, J.15
Cui, H.16
Bassuk, A.G.17
Harper, M.M.18
McKnight, S.L.19
Ready, J.M.20
Pieper, A.A.21
more..
-
70
-
-
77649290579
-
-
Yu S, Patchev AV, Wu Y, Lu J, Holsboer F, Zhang JZ Sousa N, Almeida OF (2010) Depletion of the neural precursor cell pool by glucocorticoids. Ann Neurol 67: 21-30. CrossRef Medline
-
Ann Neurol
-
-
Yu, S.1
Patchev, A.V.2
Wu, Y.3
Lu, J.4
Holsboer, F.5
Zhang, J.Z.6
Sousa, N.7
Almeida, O.F.8
|