Early detection of subclinical visual damage after blast-mediated TBI enables prevention of chronic visual deficit by treatment with P7C3-S243

Investigative Ophthalmology and Visual Science

Volumn 55, Issue 12, 2014, Pages 8330-8341

  Dutca, Laura M ^a,b   Stasheff, Steven F ^b   Hedberg Buenz, Adam ^a,b   Rudd, Danielle S ^a   Batra, Nikhil ^a   Blodi, Frederick R ^b   Yorek, Matthew S ^a   Yin, Terry ^b   Shankar, Malini ^b   Herlein, Judith A ^a   Naidoo, Jacinth ^c   Morlock, Lorraine ^c   Williams, Noelle ^c   Kardon, Randy H ^a,b   Anderson, Michael G ^a,b   Pieper, Andrew A ^b   Harper, Matthew M ^a,b  

^a DEPARTMENT OF VETERANS AFFAIRS   (United States)

^b UNIVERSITY OF IOWA   (United States)

^c UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

Blast injury; Multielectrode array; Neuroprotection; Pattern ERG; Retinal ganglion cell

Indexed keywords

N [3 (3,6 DIBROMO 9H CARBAZOL 9 YL) 2 FLUOROPROPYL] 6 METHOXYPYRIDIN 2 AMINE; NEUROPROTECTIVE AGENT; UNCLASSIFIED DRUG; CARBAZOLE DERIVATIVE; P7C3 COMPOUND;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLAST INJURY; CELL COUNT; CONTROLLED STUDY; ELECTRORETINOGRAPHY; EVOKED VISUAL RESPONSE; HISTOLOGY; INTRAOCULAR PRESSURE; LIMIT OF DETECTION; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY; MALE; MASS SPECTROMETRY; MOUSE; NONHUMAN; RETINA GANGLION CELL; SPECTRAL DOMAIN OPTICAL COHERENCE TOMOGRAPHY; TRAUMATIC BRAIN INJURY; TREATMENT OUTCOME; VISUAL DISORDER; VITREOUS BODY; ANALYSIS OF VARIANCE; ANIMAL; BLAST INJURIES; BRAIN INJURIES; C57BL MOUSE; COMPLICATION; DENDRITE; DISEASE MODEL; DRUG EFFECTS; INTRAPERITONEAL DRUG ADMINISTRATION; NERVE CELL PLASTICITY; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; VISION DISORDERS;

ANALYSIS OF VARIANCE; ANIMALS; BLAST INJURIES; BRAIN INJURIES; CARBAZOLES; CELL COUNT; DENDRITES; DISEASE MODELS, ANIMAL; ELECTRORETINOGRAPHY; INJECTIONS, INTRAPERITONEAL; MALE; MICE; MICE, INBRED C57BL; NEURONAL PLASTICITY; NEUROPROTECTIVE AGENTS; RETINAL GANGLION CELLS; VISION DISORDERS;

EID: 84919372230     PISSN: 01460404     EISSN: 15525783     Source Type: Journal    
DOI: 10.1167/iovs.14-15468     Document Type: Article

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