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Volumn 109, Issue 42, 2012, Pages 17016-17021

Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CARBAZOLE DERIVATIVE; COPPER ZINC SUPEROXIDE DISMUTASE; DIMEBON; P7C3; P7C3A20; UNCLASSIFIED DRUG;

EID: 84867639321     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213960109     Document Type: Article
Times cited : (114)

References (28)
  • 1
    • 0021809173 scopus 로고
    • Amyotrophic lateral sclerosis: Part I. Clinical features, pathology, and ethical issues in management
    • DOI 10.1002/ana.410180302
    • Tandan R, Bradley WG (1985) Amyotrophic lateral sclerosis: Part 1. Clinical features, pathology, and ethical issues in management. Ann Neurol 18:271-280. (Pubitemid 15023099)
    • (1985) Annals of Neurology , vol.18 , Issue.3 , pp. 271-280
    • Tandan, R.1    Bradley, W.G.2
  • 5
    • 22244479388 scopus 로고    scopus 로고
    • Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis
    • DOI 10.1146/annurev.biochem.72.121801.161647
    • Valentine JS, Doucette PA, Zittin Potter S (2005) Copper-zinc superoxide dismutase and amyotrophic lateral sclerosis. Annu Rev Biochem 74:563-593. (Pubitemid 40995518)
    • (2005) Annual Review of Biochemistry , vol.74 , pp. 563-593
    • Valentine, J.S.1    Doucette, P.A.2    Potter, S.Z.3
  • 7
    • 33646486372 scopus 로고    scopus 로고
    • Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice
    • Furukawa Y, Fu R, Deng HX, Siddique T, O'Halloran TV (2006) Disulfide cross-linked protein represents a significant fraction of ALS-associated Cu, Zn-superoxide dismutase aggregates in spinal cords of model mice. Proc Natl Acad Sci USA 103:7148-7153.
    • (2006) Proc Natl Acad Sci USA , vol.103 , pp. 7148-7153
    • Furukawa, Y.1    Fu, R.2    Deng, H.X.3    Siddique, T.4    O'Halloran, T.V.5
  • 8
    • 68749083546 scopus 로고    scopus 로고
    • Variation in aggregation propensities among ALS-associated variants of SOD1: Correlation to human disease
    • Prudencio M, Hart PJ, Borchelt DR, Andersen PM (2009) Variation in aggregation propensities among ALS-associated variants of SOD1: Correlation to human disease. Hum Mol Genet 18:3217-3226.
    • (2009) Hum Mol Genet , vol.18 , pp. 3217-3226
    • Prudencio, M.1    Hart, P.J.2    Borchelt, D.R.3    Andersen, P.M.4
  • 9
    • 48349090111 scopus 로고    scopus 로고
    • Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival
    • Wang Q, Johnson JL, Agar NY, Agar JN (2008) Protein aggregation and protein instability govern familial amyotrophic lateral sclerosis patient survival. PLoS Biol 6:e170.
    • (2008) PLoS Biol , vol.6
    • Wang, Q.1    Johnson, J.L.2    Agar, N.Y.3    Agar, J.N.4
  • 10
    • 33749056809 scopus 로고    scopus 로고
    • ALS: A Disease of Motor Neurons and Their Nonneuronal Neighbors
    • DOI 10.1016/j.neuron.2006.09.018, PII S0896627306007252
    • Boillée S, Vande Velde C, Cleveland DW (2006) ALS: A disease of motor neurons and their nonneuronal neighbors. Neuron 52:39-59. (Pubitemid 44466358)
    • (2006) Neuron , vol.52 , Issue.1 , pp. 39-59
    • Boillee, S.1    Vande, V.C.2    Cleveland, D.W.3
  • 13
    • 77954266958 scopus 로고    scopus 로고
    • Discovery of a proneurogenic, neuroprotective chemical
    • Pieper AA, et al. (2010) Discovery of a proneurogenic, neuroprotective chemical. Cell 142:39-51.
    • (2010) Cell , vol.142 , pp. 39-51
    • Pieper, A.A.1
  • 15
    • 79551705492 scopus 로고    scopus 로고
    • Development of proneurogenic, neuroprotective small molecules
    • MacMillan KS, et al. (2011) Development of proneurogenic, neuroprotective small molecules. J Am Chem Soc 133:1428-1437.
    • (2011) J Am Chem Soc , vol.133 , pp. 1428-1437
    • MacMillan, K.S.1
  • 19
    • 84867628671 scopus 로고    scopus 로고
    • Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease
    • De Jesús-Cortés H, et al. (2012) Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease. Proc Natl Acad Sci USA 109:17010-17015.
    • (2012) Proc Natl Acad Sci USA , vol.109 , pp. 17010-17015
    • De Jesús-Cortés, H.1
  • 22
    • 84860458565 scopus 로고    scopus 로고
    • Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS
    • Da Cruz S, et al. (2012) Elevated PGC-1α activity sustains mitochondrial biogenesis and muscle function without extending survival in a mouse model of inherited ALS. Cell Metab 15:567-569.
    • (2012) Cell Metab , vol.15 , pp. 567-569
    • Da Cruz, S.1
  • 23
    • 84864508021 scopus 로고    scopus 로고
    • Mutant superoxide dismutase 1 (SOD1), a cause of amyotrophic lateral sclerosis, disrupts the recruitment of SMN, the spinal muscular atrophy protein to nuclear Cajal bodies
    • Kariya S, et al. (2012) Mutant superoxide dismutase 1 (SOD1), a cause of amyotrophic lateral sclerosis, disrupts the recruitment of SMN, the spinal muscular atrophy protein to nuclear Cajal bodies. Hum Mol Genet 21:3421-3434.
    • (2012) Hum Mol Genet , vol.21 , pp. 3421-3434
    • Kariya, S.1
  • 25
    • 35148829836 scopus 로고    scopus 로고
    • Motor coordination and balance in rodents
    • Available at
    • Carter RJ, Morton J, Dunnet SB (2001) Motor coordination and balance in rodents. Curr Protoc Neurosci 8.12. Available at www.currentprotocols.com.
    • (2001) Curr Protoc Neurosci , vol.8 , pp. 12
    • Carter, R.J.1    Morton, J.2    Dunnet, S.B.3
  • 26
    • 45549087576 scopus 로고    scopus 로고
    • Models of amyotrophic lateral sclerosis
    • Available at
    • Jackson M, Ganel R, Rothstein JD (2002) Models of amyotrophic lateral sclerosis. Curr Protoc Neurosci 9.13. Available at www.currentprotocols.com.
    • (2002) Curr Protoc Neurosci , vol.9 , pp. 13
    • Jackson, M.1    Ganel, R.2    Rothstein, J.D.3
  • 27
    • 47149108940 scopus 로고    scopus 로고
    • Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-to-moderate Alzheimer's disease: A randomised, double-blind, placebo-controlled study
    • DOI 10.1016/S0140-6736(08)61074-0, PII S0140673608610740
    • Doody RS, et al.; dimebon investigators (2008) Effect of dimebon on cognition, activities of daily living, behaviour, and global function in patients with mild-tomoderate Alzheimer's disease: A randomised, double-blind, placebo-controlled study. Lancet 372:207-215. (Pubitemid 351978110)
    • (2008) The Lancet , vol.372 , Issue.9634 , pp. 207-215
    • Doody, R.S.1    Gavrilova, S.I.2    Sano, M.3    Thomas, R.G.4    Aisen, P.S.5    Bachurin, S.O.6    Seely, L.7    Hung, D.8
  • 28
    • 84881178228 scopus 로고    scopus 로고
    • Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model
    • 10.1038/mp.2012.106
    • Steele JW, et al. (2012) Latrepirdine improves cognition and arrests progression of neuropathology in an Alzheimer's mouse model. Mol Psych, 10.1038/mp.2012.106.
    • (2012) Mol Psych
    • Steele, J.W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.