Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of Parkinson disease

Proceedings of the National Academy of Sciences of the United States of America

Volumn 109, Issue 42, 2012, Pages 17010-17015

  De Jesús Cort́es, Héctor ^a   Xu, Pin ^a   Drawbridge, Jordan ^a   Estill, Sandi Jo ^b   Huntington, Paula ^a   Tran, Stephanie ^a   Britt, Jeremiah ^a   Tesla, Rachel ^b   Morlock, Lorraine ^b   Naidoo, Jacinth ^b   Melito, Lisa M ^b   Wang, Gelin ^b   Williams, Noelle S ^b   Ready, Joseph M ^a   McKnight, Steven L ^b   Pieper, Andrew A ^a,b,c  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^c UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CARBAZOLE DERIVATIVE; DIMEBON; P7C3; P7C3A20; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL DEATH; CONTROLLED STUDY; CORRELATION COEFFICIENT; DENTATE GYRUS; DOPAMINERGIC NERVE CELL; DOSE RESPONSE; DRUG EFFICACY; DRUG POTENCY; DRUG STRUCTURE; HIPPOCAMPUS; IMMUNOHISTOCHEMISTRY; IN VIVO STUDY; MOUSE; NERVOUS SYSTEM DEVELOPMENT; NEUROPROTECTION; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; STEM CELL; SUBSTANTIA NIGRA;

1-METHYL-4-PHENYL-1,2,3,6-TETRAHYDROPYRIDINE; 1-METHYL-4-PHENYLPYRIDINIUM; ANIMALS; APOPTOSIS; CAENORHABDITIS ELEGANS; CARBAZOLES; DOPAMINERGIC NEURONS; DOSE-RESPONSE RELATIONSHIP, DRUG; HIPPOCAMPUS; INDOLES; MICE; MICE, INBRED C57BL; MOLECULAR STRUCTURE; NEUROPROTECTIVE AGENTS; PARKINSON DISEASE; SUBSTANTIA NIGRA;

EID: 84867628671     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1213956109     Document Type: Article

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