-
1
-
-
0141741347
-
Parkinson's disease: Mechanisms and models
-
Dauer W, Przedborski S. Parkinson's disease: mechanisms and models. Neuron 2003; 39: 889-909.
-
(2003)
Neuron
, vol.39
, pp. 889-909
-
-
Dauer, W.1
Przedborski, S.2
-
2
-
-
77954266958
-
Discovery of a proneurogenic, neuroprotective chemical
-
Pieper AA, Xie S, Capota E, Estill SJ, Zhong J, Long JM et al. Discovery of a proneurogenic, neuroprotective chemical. Cell 2010; 142: 39-51.
-
(2010)
Cell
, vol.142
, pp. 39-51
-
-
Pieper, A.A.1
Xie, S.2
Capota, E.3
Estill, S.J.4
Zhong, J.5
Long, J.M.6
-
3
-
-
79551705492
-
Development of proneurogenic, neuroprotective small molecules
-
MacMillan KS, Naidoo J, Liang J, Melito L, Williams NS, Morlock L et al. Development of proneurogenic, neuroprotective small molecules. J Am Chem Soc 2011; 133: 1428-1437.
-
(2011)
J Am Chem Soc
, vol.133
, pp. 1428-1437
-
-
MacMillan, K.S.1
Naidoo, J.2
Liang, J.3
Melito, L.4
Williams, N.S.5
Morlock, L.6
-
4
-
-
84903734074
-
P7C3 and an unbiased approach to drug discovery for neurodegenerative disease
-
Pieper AA, McKnight SL, Ready JM. P7C3 and an unbiased approach to drug discovery for neurodegenerative disease. Chem Soc Rev 2014; 43: 6716-6726.
-
(2014)
Chem Soc Rev
, vol.43
, pp. 6716-6726
-
-
Pieper, A.A.1
McKnight, S.L.2
Ready, J.M.3
-
5
-
-
84907390733
-
P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage
-
Wang G, Han T, Nijhawan D, Theodoropoulos P, Naidoo J, Yadavalli S et al. P7C3 neuroprotective chemicals function by activating the rate-limiting enzyme in NAD salvage. Cell 2014; 158: 1324-1334.
-
(2014)
Cell
, vol.158
, pp. 1324-1334
-
-
Wang, G.1
Han, T.2
Nijhawan, D.3
Theodoropoulos, P.4
Naidoo, J.5
Yadavalli, S.6
-
6
-
-
84875258347
-
Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies
-
Asai-Coakwell M, March L, Dai XH, Duval M, Lopez I, French CR et al. Contribution of growth differentiation factor 6-dependent cell survival to early-onset retinal dystrophies. Hum Mol Genet 2013; 22: 1432-1442.
-
(2013)
Hum Mol Genet
, vol.22
, pp. 1432-1442
-
-
Asai-Coakwell, M.1
March, L.2
Dai, X.H.3
Duval, M.4
Lopez, I.5
French, C.R.6
-
7
-
-
84867639321
-
Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis
-
Tesla R, Wolf HP, Xu P, Drawbridge J, Estill SJ, Huntington P et al. Neuroprotective efficacy of aminopropyl carbazoles in a mouse model of amyotrophic lateral sclerosis. Proc Natl Acad Sci USA 2012; 109: 17016-17021.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 17016-17021
-
-
Tesla, R.1
Wolf, H.P.2
Xu, P.3
Drawbridge, J.4
Estill, S.J.5
Huntington, P.6
-
8
-
-
84908389399
-
Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury
-
Kemp SW, Szynkaruk M, Stanoulis KN, Wood MD, Liu EH, Willand MP et al. Pharmacologic rescue of motor and sensory function by the neuroprotective compound P7C3 following neonatal nerve injury. Neuroscience 2015; 284: 202-216.
-
(2015)
Neuroscience
, vol.284
, pp. 202-216
-
-
Kemp, S.W.1
Szynkaruk, M.2
Stanoulis, K.N.3
Wood, M.D.4
Liu, E.H.5
Willand, M.P.6
-
9
-
-
84926158983
-
The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis
-
Walker AK, Rivera PD, Wang Q, Chuang JC, Tran S, Osborne-Lawrence S et al. The P7C3 class of neuroprotective compounds exerts antidepressant efficacy in mice by increasing hippocampal neurogenesis. Mol Psychiatry 2015; 20: 500-508.
-
(2015)
Mol Psychiatry
, vol.20
, pp. 500-508
-
-
Walker, A.K.1
Rivera, P.D.2
Wang, Q.3
Chuang, J.C.4
Tran, S.5
Osborne-Lawrence, S.6
-
10
-
-
84896893675
-
Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury
-
Blaya MO, Bramlett HM, Naidoo J, Pieper AA, Dietrich WD. Neuroprotective efficacy of a proneurogenic compound after traumatic brain injury. J Neurotrauma 2014; 31: 476-486.
-
(2014)
J Neurotrauma
, vol.31
, pp. 476-486
-
-
Blaya, M.O.1
Bramlett, H.M.2
Naidoo, J.3
Pieper, A.A.4
Dietrich, W.D.5
-
11
-
-
84907413877
-
P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury
-
Yin TC, Britt JK, De Jesús-Cortés H, Lu Y, Genova RM, Khan MZ et al. P7C3 neuroprotective chemicals block axonal degeneration and preserve function after traumatic brain injury. Cell Rep 2014; 8: 1731-1740.
-
(2014)
Cell Rep
, vol.8
, pp. 1731-1740
-
-
Yin, T.C.1
Britt, J.K.2
De Jesús-Cortés, H.3
Lu, Y.4
Genova, R.M.5
Khan, M.Z.6
-
12
-
-
84919372230
-
Early and noninvasive detection of subclinical visual damage after blast-mediated traumatic brain injury enables prevention of chronic visual deficit by treatment with P7C3- S243
-
Dutca LM, Stasheff SF, Heberg-Buenz A, Rudd D, Batra N, Blodi FR et al. Early and noninvasive detection of subclinical visual damage after blast-mediated traumatic brain injury enables prevention of chronic visual deficit by treatment with P7C3- S243. Invest Ophthalmol Vis Sci 2014; 55: 8330-8341.
-
(2014)
Invest Ophthalmol Vis Sci
, vol.55
, pp. 8330-8341
-
-
Dutca, L.M.1
Stasheff, S.F.2
Heberg-Buenz, A.3
Rudd, D.4
Batra, N.5
Blodi, F.R.6
-
13
-
-
84979077780
-
NAMPT neuroprotection
-
Cain C. NAMPT neuroprotection. SciBX 2014; 7: 1-2.
-
(2014)
SciBX
, vol.7
, pp. 1-2
-
-
Cain, C.1
-
14
-
-
84867628671
-
Neuroprotective efficacy of aminopropyl carabzoles in a mouse model of Parkinson disease
-
De Jesús-Cortés H, Xu P, Drawbridge J, Estill SJ, Huntington P, Tran S et al. Neuroprotective efficacy of aminopropyl carabzoles in a mouse model of Parkinson disease. Proc Natl Acad Sci USA 2012; 109: 17010-17015.
-
(2012)
Proc Natl Acad Sci USA
, vol.109
, pp. 17010-17015
-
-
De Jesús-Cortés, H.1
Xu, P.2
Drawbridge, J.3
Estill, S.J.4
Huntington, P.5
Tran, S.6
-
15
-
-
84900318312
-
Discovery of a neuroprotective chemical, (S)-N-(3-(3, 6-dibromo-9H-carbazol-9-yl)- 2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties
-
Naidoo J, De Jesus-Cortes H, Huntington P, Estill S, Morlock LK, Starwalt R et al. Discovery of a neuroprotective chemical, (S)-N-(3-(3, 6-dibromo-9H-carbazol-9-yl)- 2-fluoropropyl)-6-methoxypyridin-2-amine [(-)-P7C3-S243], with improved druglike properties. J Med Chem 2014; 57: 3746-3754.
-
(2014)
J Med Chem
, vol.57
, pp. 3746-3754
-
-
Naidoo, J.1
De Jesus-Cortes, H.2
Huntington, P.3
Estill, S.4
Morlock, L.K.5
Starwalt, R.6
-
16
-
-
5544229693
-
Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP
-
Schober A. Classic toxin-induced animal models of Parkinson's disease: 6-OHDA and MPTP. Cell Tissue Re 2004; 318: 215-224.
-
(2004)
Cell Tissue Re
, vol.318
, pp. 215-224
-
-
Schober, A.1
-
17
-
-
3042845122
-
Vivo characterization of somatodendritic release in the substantia nigra of 6-hydroxydopamine-lesioned rats
-
Sarre S, Yuan H, Jonker N, Ven Hemelrijck A, Ebinger G, Michotte Y. In vivo characterization of somatodendritic release in the substantia nigra of 6-hydroxydopamine-lesioned rats. J Neurochem 2004; 90: 29-39.
-
(2004)
J Neurochem
, vol.90
, pp. 29-39
-
-
Sarre, S.1
Yuan, H.2
Jonker, N.3
Ven Hemelrijck, A.4
Ebinger, G.5
Michotte, Y.6
-
18
-
-
53149084121
-
Opening of the blood-brain barrier during isoflurane anaesthesia
-
Tétrault S, Chever O, Sik A, Amzica F. Opening of the blood-brain barrier during isoflurane anaesthesia. Eur J Neurosci 2008; 28: 1330-1341.
-
(2008)
Eur J Neurosci
, vol.28
, pp. 1330-1341
-
-
Tétrault, S.1
Chever, O.2
Sik, A.3
Amzica, F.4
-
19
-
-
84862493568
-
Isoflurane induces endothelial apoptosis of the post-hypoxic blood-brain barrier in a transdifferentiated human umbilical vein endothelial cell model
-
Dittmar MS, Petermichl W, Schlachetzki F, Graf BM, Gruber M. Isoflurane induces endothelial apoptosis of the post-hypoxic blood-brain barrier in a transdifferentiated human umbilical vein endothelial cell model. PLoS One 2012; 7: e38260.
-
(2012)
PLoS One
, vol.7
, pp. e38260
-
-
Dittmar, M.S.1
Petermichl, W.2
Schlachetzki, F.3
Graf, B.M.4
Gruber, M.5
-
20
-
-
84918822259
-
Isoflurane anesthesia results in reversible ultrastructure and occludin tight junction protein expression changes in hippocampal blood-brain barrier in aged rats
-
Cao Y, Ni C, Li Z, Li L, Liu Y, Wang C et al. Isoflurane anesthesia results in reversible ultrastructure and occludin tight junction protein expression changes in hippocampal blood-brain barrier in aged rats. Neurosci Lett 2015; 587: 51-56.
-
(2015)
Neurosci Lett
, vol.587
, pp. 51-56
-
-
Cao, Y.1
Ni, C.2
Li, Z.3
Li, L.4
Liu, Y.5
Wang, C.6
-
21
-
-
0033950675
-
CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury
-
Schallert T, Fleming SM, Leasure JL, Tillerson JL, Bland ST. CNS plasticity and assessment of forelimb sensorimotor outcome in unilateral rat models of stroke, cortical ablation, parkinsonism and spinal cord injury. Neuropharmacology 2000; 39: 777-787.
-
(2000)
Neuropharmacology
, vol.39
, pp. 777-787
-
-
Schallert, T.1
Fleming, S.M.2
Leasure, J.L.3
Tillerson, J.L.4
Bland, S.T.5
-
22
-
-
0028281985
-
Relationship between asymmetries in striatal dopamine release and the direction of amphetamine-induced rotation during the first week following a unilateral 6- OHDA lesion of the substantia nigra
-
Robinson TE, Noordhoom M, Chan EM, Mocsary Z, Camp DM, Whishaw IQ. Relationship between asymmetries in striatal dopamine release and the direction of amphetamine-induced rotation during the first week following a unilateral 6- OHDA lesion of the substantia nigra. Synapse 1994; 17: 16-25.
-
(1994)
Synapse
, vol.17
, pp. 16-25
-
-
Robinson, T.E.1
Noordhoom, M.2
Chan, E.M.3
Mocsary, Z.4
Camp, D.M.5
Whishaw, I.Q.6
-
23
-
-
48349146711
-
Human interleukin-10 gene transfer is protective in a rat model of Parkinson's disease
-
Johnston LC, Su X, Maguire-Zeiss K, Horovitz K, Ankoudinova I, Guschin D et al. Human interleukin-10 gene transfer is protective in a rat model of Parkinson's disease. Mol Ther 2008; 16: 1392-1399.
-
(2008)
Mol Ther
, vol.16
, pp. 1392-1399
-
-
Johnston, L.C.1
Su, X.2
Maguire-Zeiss, K.3
Horovitz, K.4
Ankoudinova, I.5
Guschin, D.6
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