메뉴 건너뛰기




Volumn 22, Issue 23, 2013, Pages 4673-4687

The UPF3B gene, implicated in intellectual disability, autism, ADHD and childhood onset schizophrenia regulates neural progenitor cell behaviour and neuronal outgrowth

Author keywords

[No Author keywords available]

Indexed keywords

LENTIVIRUS VECTOR; MESSENGER RNA; SHORT HAIRPIN RNA;

EID: 84887562180     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddt315     Document Type: Article
Times cited : (97)

References (70)
  • 1
    • 77957968873 scopus 로고    scopus 로고
    • Genetics of early onset cognitive impairment
    • Ropers, H.H. (2010) Genetics of early onset cognitive impairment. Annu. Rev. Genomics Hum. Genet., 11, 161-187.
    • (2010) Annu. Rev. Genomics Hum. Genet. , vol.11 , pp. 161-187
    • Ropers, H.H.1
  • 3
    • 67649921127 scopus 로고    scopus 로고
    • The genetic landscape of intellectual disability arising from chromosome X
    • Gecz, J., Shoubridge, C. and Corbett, M. (2009) The genetic landscape of intellectual disability arising from chromosome X. Trends Genet., 25, 308- 316.
    • (2009) Trends Genet , vol.25 , pp. 308-316
    • Gecz, J.1    Shoubridge, C.2    Corbett, M.3
  • 5
    • 77953914253 scopus 로고    scopus 로고
    • Mutations of the UPF3B gene, which encodes a protein widely expressed in neurons, are associated with nonspecific mental retardation with or without autism
    • Laumonnier, F., Shoubridge, C., Antar, C., Nguyen, L.S., Van Esch, H., Kleefstra, T., Briault, S., Fryns, J.P., Hamel, B., Chelly, J. et al. (2010) Mutations of the UPF3B gene, which encodes a protein widely expressed in neurons, are associated with nonspecific mental retardation with or without autism. Mol. Psychiatry, 15, 767-776.
    • (2010) Mol. Psychiatry , vol.15 , pp. 767-776
    • Laumonnier, F.1    Shoubridge, C.2    Antar, C.3    Nguyen, L.S.4    Van Esch, H.5    Kleefstra, T.6    Briault, S.7    Fryns, J.P.8    Hamel, B.9    Chelly, J.10
  • 6
    • 84864123489 scopus 로고    scopus 로고
    • Broadening the phenotype associated with mutations in UPF3B: Two further cases with renal dysplasia and variable developmental delay
    • Lynch, S.A., Nguyen, L.S., Ng, L.Y., Waldron, M., McDonald, D. and Gecz, J. (2012) Broadening the phenotype associated with mutations in UPF3B: Two further cases with renal dysplasia and variable developmental delay. Eur. J. Med. Genet., 55, 476-479.
    • (2012) Eur. J. Med. Genet. , vol.55 , pp. 476-479
    • Lynch, S.A.1    Nguyen, L.S.2    Ng, L.Y.3    Waldron, M.4    McDonald, D.5    Gecz, J.6
  • 8
    • 84876814034 scopus 로고    scopus 로고
    • Exome sequencing identifies UPF3B as the causative gene for a Chinese non-syndrome mental retardation pedigree
    • Xu, X., Zhang, L., Tong, P., Xun, G., Su, W., Xiong, Z., Zhu, T., Zheng, Y., Luo, S., Pan, Y. et al. (2012) Exome sequencing identifies UPF3B as the causative gene for a Chinese non-syndrome mental retardation pedigree. Clin. Genet., 83, 560-564.
    • (2012) Clin. Genet. , vol.83 , pp. 560-564
    • Xu, X.1    Zhang, L.2    Tong, P.3    Xun, G.4    Su, W.5    Xiong, Z.6    Zhu, T.7    Zheng, Y.8    Luo, S.9    Pan, Y.10
  • 10
    • 77949904260 scopus 로고    scopus 로고
    • Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors
    • Nicholson, P., Yepiskoposyan, H., Metze, S., Zamudio Orozco, R., Kleinschmidt, N. and Muhlemann, O. (2010) Nonsense-mediated mRNA decay in human cells: mechanistic insights, functions beyond quality control and the double-life of NMD factors. Cell. Mol. Life Sci., 67, 677-700.
    • (2010) Cell. Mol. Life Sci. , vol.67 , pp. 677-700
    • Nicholson, P.1    Yepiskoposyan, H.2    Metze, S.3    Zamudio Orozco, R.4    Kleinschmidt, N.5    Muhlemann, O.6
  • 12
    • 0035823150 scopus 로고    scopus 로고
    • Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon- exon junction complex
    • Kim, V.N., Kataoka, N. and Dreyfuss, G. (2001) Role of the nonsense-mediated decay factor hUpf3 in the splicing-dependent exon- exon junction complex. Science, 293, 1832-1836.
    • (2001) Science , vol.293 , pp. 1832-1836
    • Kim, V.N.1    Kataoka, N.2    Dreyfuss, G.3
  • 13
    • 37849005006 scopus 로고    scopus 로고
    • NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity
    • Chamieh, H., Ballut, L., Bonneau, F. and Le Hir, H. (2008) NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity. Nat. Struct. Mol. Biol., 15, 85-93.
    • (2008) Nat. Struct. Mol. Biol. , vol.15 , pp. 85-93
    • Chamieh, H.1    Ballut, L.2    Bonneau, F.3    Le Hir, H.4
  • 14
    • 32044435368 scopus 로고    scopus 로고
    • Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediatedmRNAdecay
    • Kashima, I., Yamashita, A., Izumi, N., Kataoka, N., Morishita, R., Hoshino, S., Ohno, M., Dreyfuss, G. and Ohno, S. (2006) Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediatedmRNAdecay. Genes Dev., 20, 355-367.
    • (2006) Genes Dev , vol.20 , pp. 355-367
    • Kashima, I.1    Yamashita, A.2    Izumi, N.3    Kataoka, N.4    Morishita, R.5    Hoshino, S.6    Ohno, M.7    Dreyfuss, G.8    Ohno, S.9
  • 15
    • 40949148553 scopus 로고    scopus 로고
    • Interactions between UPF1, eRFs PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways
    • Ivanov, P.V., Gehring, N.H., Kunz, J.B., Hentze, M.W. and Kulozik, A.E. (2008) Interactions between UPF1, eRFs, PABP and the exon junction complex suggest an integrated model for mammalian NMD pathways. EMBO J., 27, 736-747.
    • (2008) EMBO J , vol.27 , pp. 736-747
    • Ivanov, P.V.1    Gehring, N.H.2    Kunz, J.B.3    Hentze, M.W.4    Kulozik, A.E.5
  • 16
    • 43249084802 scopus 로고    scopus 로고
    • A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay
    • Singh, G., Rebbapragada, I. and Lykke-Andersen, J. (2008) A competition between stimulators and antagonists of Upf complex recruitment governs human nonsense-mediated mRNA decay. PLoS Biol., 6, e111.
    • (2008) PLoS Biol , vol.6
    • Singh, G.1    Rebbapragada, I.2    Lykke-Andersen, J.3
  • 19
    • 6944256813 scopus 로고    scopus 로고
    • Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise
    • Mendell, J.T., Sharifi, N.A., Meyers, J.L., Martinez-Murillo, F. and Dietz, H.C. (2004) Nonsense surveillance regulates expression of diverse classes of mammalian transcripts and mutes genomic noise. Nat. Genet., 36, 1073- 1078.
    • (2004) Nat. Genet. , vol.36 , pp. 1073-1078
    • Mendell, J.T.1    Sharifi, N.A.2    Meyers, J.L.3    Martinez-Murillo, F.4    Dietz, H.C.5
  • 20
    • 32044454232 scopus 로고    scopus 로고
    • hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay
    • Wittmann, J., Hol, E.M. and Jack, H.M. (2006) hUPF2 silencing identifies physiologic substrates of mammalian nonsense-mediated mRNA decay. Mol. Cell Biol., 26, 1272-1287.
    • (2006) Mol. Cell Biol. , vol.26 , pp. 1272-1287
    • Wittmann, J.1    Hol, E.M.2    Jack, H.M.3
  • 22
    • 25844435702 scopus 로고    scopus 로고
    • Nonsense-mediatedmRNAdecay factors act in concert to regulate common mRNA targets
    • Rehwinkel, J., Letunic, I., Raes, J., Bork, P. and Izaurralde, E. (2005) Nonsense-mediatedmRNAdecay factors act in concert to regulate common mRNA targets. RNA, 11, 1530-1544.
    • (2005) RNA , vol.11 , pp. 1530-1544
    • Rehwinkel, J.1    Letunic, I.2    Raes, J.3    Bork, P.4    Izaurralde, E.5
  • 23
    • 0347416978 scopus 로고    scopus 로고
    • Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5′ to 3′ mRNA decay pathways in yeast
    • He, F., Li, X., Spatrick, P., Casillo, R., Dong, S. and Jacobson, A. (2003) Genome-wide analysis of mRNAs regulated by the nonsense-mediated and 5′ to 3′ mRNA decay pathways in yeast. Mol. Cell, 12, 1439-1452.
    • (2003) Mol. Cell , vol.12 , pp. 1439-1452
    • He, F.1    Li, X.2    Spatrick, P.3    Casillo, R.4    Dong, S.5    Jacobson, A.6
  • 24
    • 0035862813 scopus 로고    scopus 로고
    • Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability
    • Medghalchi, S.M., Frischmeyer, P.A., Mendell, J.T., Kelly, A.G., Lawler, A.M. and Dietz, H.C. (2001) Rent1, a trans-effector of nonsense-mediated mRNA decay, is essential for mammalian embryonic viability. Hum. Mol. Genet., 10, 99-105.
    • (2001) Hum. Mol. Genet. , vol.10 , pp. 99-105
    • Medghalchi, S.M.1    Frischmeyer, P.A.2    Mendell, J.T.3    Kelly, A.G.4    Lawler, A.M.5    Dietz, H.C.6
  • 25
    • 25844512736 scopus 로고    scopus 로고
    • Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements
    • Gehring, N.H., Kunz, J.B., Neu-Yilik, G., Breit, S., Viegas, M.H., Hentze, M.W. and Kulozik, A.E. (2005) Exon-junction complex components specify distinct routes of nonsense-mediated mRNA decay with differential cofactor requirements. Mol. Cell., 20, 65-75.
    • (2005) Mol. Cell. , vol.20 , pp. 65-75
    • Gehring, N.H.1    Kunz, J.B.2    Neu-Yilik, G.3    Breit, S.4    Viegas, M.H.5    Hentze, M.W.6    Kulozik, A.E.7
  • 26
    • 58149520665 scopus 로고    scopus 로고
    • SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs
    • Gong, C., Kim, Y.K., Woeller, C.F., Tang, Y. and Maquat, L.E. (2009)SMD and NMD are competitive pathways that contribute to myogenesis: effects on PAX3 and myogenin mRNAs. Genes Dev., 23, 54-66.
    • (2009) Genes Dev , vol.23 , pp. 54-66
    • Gong, C.1    Kim, Y.K.2    Woeller, C.F.3    Tang, Y.4    Maquat, L.E.5
  • 27
    • 70450182086 scopus 로고    scopus 로고
    • Gene expression networks: competing mRNA decay pathways in mammalian cells
    • Maquat, L.E. and Gong, C. (2009) Gene expression networks: competing mRNA decay pathways in mammalian cells. Biochem. Soc. Trans., 37, 1287-1292.
    • (2009) Biochem. Soc. Trans. , vol.37 , pp. 1287-1292
    • Maquat, L.E.1    Gong, C.2
  • 28
    • 12944327374 scopus 로고    scopus 로고
    • Mammalian Staufen1 recruits Upf1 to specificmRNA3 ′ UTRs so as to elicit mRNA decay
    • Kim, Y.K., Furic, L., Desgroseillers, L. and Maquat, L.E. (2005) Mammalian Staufen1 recruits Upf1 to specificmRNA3 ′ UTRs so as to elicit mRNA decay. Cell, 120, 195-208.
    • (2005) Cell , vol.120 , pp. 195-208
    • Kim, Y.K.1    Furic, L.2    Desgroseillers, L.3    Maquat, L.E.4
  • 33
    • 34347384211 scopus 로고    scopus 로고
    • A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons
    • Boutz, P.L., Stoilov, P., Li, Q., Lin, C.H., Chawla, G., Ostrow, K., Shiue, L., Ares, M. Jr and Black, D.L. (2007) A post-transcriptional regulatory switch in polypyrimidine tract-binding proteins reprograms alternative splicing in developing neurons. Genes Dev., 21, 1636-1652.
    • (2007) Genes Dev , vol.21 , pp. 1636-1652
    • Boutz, P.L.1    Stoilov, P.2    Li, Q.3    Lin, C.H.4    Chawla, G.5    Ostrow, K.6    Shiue, L.7    Ares Jr., M.8    Black, D.L.9
  • 34
    • 34547212309 scopus 로고    scopus 로고
    • The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing
    • Makeyev, E.V., Zhang, J., Carrasco, M.A. and Maniatis, T. (2007) The MicroRNA miR-124 promotes neuronal differentiation by triggering brain-specific alternative pre-mRNA splicing. Mol. Cell, 27, 435-448.
    • (2007) Mol. Cell , vol.27 , pp. 435-448
    • Makeyev, E.V.1    Zhang, J.2    Carrasco, M.A.3    Maniatis, T.4
  • 35
    • 84857653757 scopus 로고    scopus 로고
    • PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2
    • S381
    • Zheng, S., Gray, E.E., Chawla, G., Porse, B.T., O'Dell, T.J. and Black, D.L. (2012) PSD-95 is post-transcriptionally repressed during early neural development by PTBP1 and PTBP2. Nat. Neurosci., 15, 381-388, S381.
    • (2012) Nat. Neurosci. , vol.15 , pp. 381-388
    • Zheng, S.1    Gray, E.E.2    Chawla, G.3    Porse, B.T.4    O'Dell, T.J.5    Black, D.L.6
  • 36
    • 34447092677 scopus 로고    scopus 로고
    • The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression
    • Giorgi, C., Yeo, G.W., Stone, M.E., Katz, D.B., Burge, C., Turrigiano, G. and Moore, M.J. (2007) The EJC factor eIF4AIII modulates synaptic strength and neuronal protein expression. Cell, 130, 179-191.
    • (2007) Cell , vol.130 , pp. 179-191
    • Giorgi, C.1    Yeo, G.W.2    Stone, M.E.3    Katz, D.B.4    Burge, C.5    Turrigiano, G.6    Moore, M.J.7
  • 37
    • 34548864370 scopus 로고    scopus 로고
    • Culturing hippocampal neurons
    • Kaech, S. and Banker, G. (2006) Culturing hippocampal neurons. Nat. Protoc., 1, 2406-2415.
    • (2006) Nat. Protoc. , vol.1 , pp. 2406-2415
    • Kaech, S.1    Banker, G.2
  • 38
    • 0037014456 scopus 로고    scopus 로고
    • Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function
    • Murase, S., Mosser, E. and Schuman, E.M. (2002) Depolarization drives beta-Catenin into neuronal spines promoting changes in synaptic structure and function. Neuron, 35, 91-105.
    • (2002) Neuron , vol.35 , pp. 91-105
    • Murase, S.1    Mosser, E.2    Schuman, E.M.3
  • 39
    • 59749101236 scopus 로고    scopus 로고
    • Isolation and manipulation of mammalian neural stem cells in vitro
    • Giachino, C., Basak, O. and Taylor, V. (2009) Isolation and manipulation of mammalian neural stem cells in vitro. Methods Mol. Biol., 482, 143-158.
    • (2009) Methods Mol. Biol. , vol.482 , pp. 143-158
    • Giachino, C.1    Basak, O.2    Taylor, V.3
  • 41
    • 78651284871 scopus 로고    scopus 로고
    • Lentivirus-mediated expression of insulin-like growth factor-I promotes neural stem/precursor cell proliferation and enhances their potential to generate neurons
    • Kouroupi, G., Lavdas, A.A., Gaitanou, M., Thomaidou, D., Stylianopoulou, F. and Matsas, R. (2010) Lentivirus-mediated expression of insulin-like growth factor-I promotes neural stem/precursor cell proliferation and enhances their potential to generate neurons. J. Neurochem., 115, 460-474.
    • (2010) J. Neurochem. , vol.115 , pp. 460-474
    • Kouroupi, G.1    Lavdas, A.A.2    Gaitanou, M.3    Thomaidou, D.4    Stylianopoulou, F.5    Matsas, R.6
  • 42
    • 0035899505 scopus 로고    scopus 로고
    • Purification of a pluripotent neural stem cell from the adult mouse brain
    • Rietze, R.L., Valcanis, H., Brooker, G.F., Thomas, T., Voss, A.K. and Bartlett, P.F. (2001) Purification of a pluripotent neural stem cell from the adult mouse brain. Nature, 412, 736-739.
    • (2001) Nature , vol.412 , pp. 736-739
    • Rietze, R.L.1    Valcanis, H.2    Brooker, G.F.3    Thomas, T.4    Voss, A.K.5    Bartlett, P.F.6
  • 43
    • 0037194887 scopus 로고    scopus 로고
    • LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal
    • Capela, A. and Temple, S. (2002) LeX/ssea-1 is expressed by adult mouse CNS stem cells, identifying them as nonependymal. Neuron, 35, 865-875.
    • (2002) Neuron , vol.35 , pp. 865-875
    • Capela, A.1    Temple, S.2
  • 44
    • 0344011434 scopus 로고    scopus 로고
    • Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis
    • Kim,M.and Morshead, C.M. (2003) Distinct populations of forebrain neural stem and progenitor cells can be isolated using side-population analysis. J. Neurosci., 23, 10703-10709.
    • (2003) J. Neurosci. , vol.23 , pp. 10703-10709
    • Kim, M.1    and Morshead, C.M.2
  • 45
    • 0029983762 scopus 로고    scopus 로고
    • Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell
    • Reynolds, B.A. and Weiss, S. (1996) Clonal and population analyses demonstrate that an EGF-responsive mammalian embryonic CNS precursor is a stem cell. Dev. Biol., 175, 1-13.
    • (1996) Dev. Biol. , vol.175 , pp. 1-13
    • Reynolds, B.A.1    Weiss, S.2
  • 48
    • 67649441084 scopus 로고    scopus 로고
    • Nuclear transport factors in neuronal function
    • Perry, R.B. and Fainzilber, M. (2009) Nuclear transport factors in neuronal function. Semin. Cell Dev. Biol., 20, 600-606.
    • (2009) Semin. Cell Dev. Biol. , vol.20 , pp. 600-606
    • Perry, R.B.1    Fainzilber, M.2
  • 49
    • 67649452381 scopus 로고    scopus 로고
    • The role of the nuclear transport system in cell differentiation
    • Yasuhara, N., Oka, M. and Yoneda, Y. (2009) The role of the nuclear transport system in cell differentiation. Semin. Cell Dev. Biol., 20, 590-599.
    • (2009) Semin. Cell Dev. Biol. , vol.20 , pp. 590-599
    • Yasuhara, N.1    Oka, M.2    Yoneda, Y.3
  • 50
    • 33644969011 scopus 로고    scopus 로고
    • The role of mammalian Staufen onmRNAtraffic: a view from its nucleocytoplasmic shuttling function
    • Miki, T., Takano, K. and Yoneda, Y. (2005) The role of mammalian Staufen onmRNAtraffic: a view from its nucleocytoplasmic shuttling function. Cell Struct. Funct., 30, 51-56.
    • (2005) Cell Struct. Funct. , vol.30 , pp. 51-56
    • Miki, T.1    Takano, K.2    Yoneda, Y.3
  • 51
    • 0026535505 scopus 로고
    • Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system
    • Reynolds, B.A. and Weiss, S. (1992) Generation of neurons and astrocytes from isolated cells of the adult mammalian central nervous system. Science, 255, 1707-1710.
    • (1992) Science , vol.255 , pp. 1707-1710
    • Reynolds, B.A.1    Weiss, S.2
  • 55
    • 33751109710 scopus 로고    scopus 로고
    • Six3 activation of Pax6 expression is essential for mammalian lens induction and specification
    • Liu, W., Lagutin, O.V., Mende, M., Streit, A. and Oliver, G. (2006) Six3 activation of Pax6 expression is essential for mammalian lens induction and specification. EMBO J., 25, 5383-5395.
    • (2006) EMBO J , vol.25 , pp. 5383-5395
    • Liu, W.1    Lagutin, O.V.2    Mende, M.3    Streit, A.4    Oliver, G.5
  • 57
    • 84856854101 scopus 로고    scopus 로고
    • The role of NrCAM in neural development and disorders-beyond a simple glue in the brain
    • Sakurai, T. (2012) The role of NrCAM in neural development and disorders-beyond a simple glue in the brain. Mol. Cell Neurosci., 49, 351-363.
    • (2012) Mol. Cell Neurosci. , vol.49 , pp. 351-363
    • Sakurai, T.1
  • 58
    • 80052632680 scopus 로고    scopus 로고
    • Robo1 and Robo2 have distinct roles in pioneer longitudinal axon guidance
    • Kim, M., Roesener, A.P., Mendonca, P.R. and Mastick, G.S. (2011) Robo1 and Robo2 have distinct roles in pioneer longitudinal axon guidance. Dev. Biol., 358, 181-188.
    • (2011) Dev. Biol. , vol.358 , pp. 181-188
    • Kim, M.1    Roesener, A.P.2    Mendonca, P.R.3    Mastick, G.S.4
  • 64
  • 65
    • 65249120839 scopus 로고    scopus 로고
    • USP9X enhances the polarity and self-renewal of embryonic stem cell-derived neural progenitors
    • Jolly, L.A., Taylor, V. and Wood, S.A. (2009) USP9X enhances the polarity and self-renewal of embryonic stem cell-derived neural progenitors. Mol. Biol. Cell., 20, 2015-2029.
    • (2009) Mol. Biol. Cell. , vol.20 , pp. 2015-2029
    • Jolly, L.A.1    Taylor, V.2    Wood, S.A.3
  • 67
    • 0034919136 scopus 로고    scopus 로고
    • Lentivirus vectors encoding both central polypurine tract and posttranscriptional regulatory element provide enhanced transduction and transgene expression
    • Barry, S.C., Harder, B., Brzezinski, M., Flint, L.Y., Seppen, J. and Osborne, W.R. (2001) Lentivirus vectors encoding both central polypurine tract and posttranscriptional regulatory element provide enhanced transduction and transgene expression. Hum. Gene Ther., 12, 1103-1108.
    • (2001) Hum. Gene Ther. , vol.12 , pp. 1103-1108
    • Barry, S.C.1    Harder, B.2    Brzezinski, M.3    Flint, L.Y.4    Seppen, J.5    Osborne, W.R.6
  • 68
    • 33847181714 scopus 로고    scopus 로고
    • Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression
    • Basak, O. and Taylor, V. (2007) Identification of self-replicating multipotent progenitors in the embryonic nervous system by high Notch activity and Hes5 expression. Eur. J. Neurosci., 25, 1006-1022.
    • (2007) Eur. J. Neurosci. , vol.25 , pp. 1006-1022
    • Basak, O.1    Taylor, V.2
  • 70
    • 33947721728 scopus 로고    scopus 로고
    • Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages
    • Meinen, S., Barzaghi, P., Lin, S., Lochmuller, H. and Ruegg, M.A. (2007) Linker molecules between laminins and dystroglycan ameliorate laminin-alpha2-deficient muscular dystrophy at all disease stages. J. Cell Biol., 176, 979-993.
    • (2007) J. Cell Biol. , vol.176 , pp. 979-993
    • Meinen, S.1    Barzaghi, P.2    Lin, S.3    Lochmuller, H.4    Ruegg, M.A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.