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Volumn 66, Issue 2, 2017, Pages 449-465

Characterization of ferroptosis in murine models of hemochromatosis

Author keywords

[No Author keywords available]

Indexed keywords

ALANINE AMINOTRANSFERASE; GLUTATHIONE; MALONALDEHYDE; NUCLEAR PROTEIN; PROTEIN; SLC7A11 PROTEIN; UNCLASSIFIED DRUG; FERRIC CITRATE; FERRIC ION; IRON; IRON CHELATING AGENT; MCH1R PROTEIN, MOUSE; SOMATOSTATIN RECEPTOR;

EID: 85019186592     PISSN: 02709139     EISSN: 15273350     Source Type: Journal    
DOI: 10.1002/hep.29117     Document Type: Article
Times cited : (514)

References (47)
  • 1
    • 84885768132 scopus 로고    scopus 로고
    • Systemic iron homeostasis
    • Ganz T. Systemic iron homeostasis. Physiol Rev 2013;93:1721-1741.
    • (2013) Physiol Rev , vol.93 , pp. 1721-1741
    • Ganz, T.1
  • 2
    • 84892657750 scopus 로고    scopus 로고
    • The liver: conductor of systemic iron balance
    • Meynard D, Babitt JL, Lin HY. The liver: conductor of systemic iron balance. Blood 2014;123:168-176.
    • (2014) Blood , vol.123 , pp. 168-176
    • Meynard, D.1    Babitt, J.L.2    Lin, H.Y.3
  • 4
    • 77955508573 scopus 로고    scopus 로고
    • Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment
    • Pietrangelo A. Hereditary hemochromatosis: pathogenesis, diagnosis, and treatment. Gastroenterology 2010;139:393-408.
    • (2010) Gastroenterology , vol.139 , pp. 393-408
    • Pietrangelo, A.1
  • 6
    • 84890922670 scopus 로고    scopus 로고
    • The role of iron and reactive oxygen species in cell death
    • Dixon SJ, Stockwell BR. The role of iron and reactive oxygen species in cell death. Nat Chem Biol 2014;10:9-17.
    • (2014) Nat Chem Biol , vol.10 , pp. 9-17
    • Dixon, S.J.1    Stockwell, B.R.2
  • 9
    • 84965008627 scopus 로고    scopus 로고
    • Cell-line selectivity improves the predictive power of pharmacogenomic analyses and helps identify NADPH as biomarker for ferroptosis sensitivity
    • Shimada K, Hayano M, Pagano NC, Stockwell BR. Cell-line selectivity improves the predictive power of pharmacogenomic analyses and helps identify NADPH as biomarker for ferroptosis sensitivity. Cell Chem Biol 2016;23:225-235.
    • (2016) Cell Chem Biol , vol.23 , pp. 225-235
    • Shimada, K.1    Hayano, M.2    Pagano, N.C.3    Stockwell, B.R.4
  • 10
    • 84958103915 scopus 로고    scopus 로고
    • Ferroptosis: death by lipid peroxidation
    • Yang WS, Stockwell BR. Ferroptosis: death by lipid peroxidation. Trends Cell Biol 2016;26:165-176.
    • (2016) Trends Cell Biol , vol.26 , pp. 165-176
    • Yang, W.S.1    Stockwell, B.R.2
  • 12
    • 84952639010 scopus 로고    scopus 로고
    • Activation of the p62–Keap1–NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
    • Sun X, Ou Z, Chen R, Niu X, Chen D, Kang R, et al. Activation of the p62–Keap1–NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells. Hepatology 2016;63:173-184.
    • (2016) Hepatology , vol.63 , pp. 173-184
    • Sun, X.1    Ou, Z.2    Chen, R.3    Niu, X.4    Chen, D.5    Kang, R.6
  • 13
    • 84978997718 scopus 로고    scopus 로고
    • Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis
    • Sun X, Niu X, Chen R, He W, Chen D, Kang R, et al. Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis. Hepatology 2016;64:488-500.
    • (2016) Hepatology , vol.64 , pp. 488-500
    • Sun, X.1    Niu, X.2    Chen, R.3    He, W.4    Chen, D.5    Kang, R.6
  • 14
    • 84937525519 scopus 로고    scopus 로고
    • Glutaminolysis and transferrin regulate ferroptosis
    • Gao M, Monian P, Quadri N, Ramasamy R, Jiang X. Glutaminolysis and transferrin regulate ferroptosis. Mol Cell 2015;59:298-308.
    • (2015) Mol Cell , vol.59 , pp. 298-308
    • Gao, M.1    Monian, P.2    Quadri, N.3    Ramasamy, R.4    Jiang, X.5
  • 15
    • 84943390843 scopus 로고    scopus 로고
    • Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death
    • Kwon MY, Park E, Lee SJ, Chung SW. Heme oxygenase-1 accelerates erastin-induced ferroptotic cell death. Oncotarget 2015;6:24393-24403.
    • (2015) Oncotarget , vol.6 , pp. 24393-24403
    • Kwon, M.Y.1    Park, E.2    Lee, S.J.3    Chung, S.W.4
  • 16
    • 0033597349 scopus 로고    scopus 로고
    • Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins
    • Sato H, Tamba M, Ishii T, Bannai S. Cloning and expression of a plasma membrane cystine/glutamate exchange transporter composed of two distinct proteins. J Biol Chem 1999;274:11455-11458.
    • (1999) J Biol Chem , vol.274 , pp. 11455-11458
    • Sato, H.1    Tamba, M.2    Ishii, T.3    Bannai, S.4
  • 17
    • 0024432603 scopus 로고
    • Regulation of cellular glutathione
    • Deneke SM, Fanburg BL. Regulation of cellular glutathione. Am J Physiol 1989;257:L163-L173.
    • (1989) Am J Physiol , vol.257 , pp. L163-L173
    • Deneke, S.M.1    Fanburg, B.L.2
  • 18
    • 84958729887 scopus 로고    scopus 로고
    • A glutathione–Nrf2–thioredoxin cross-talk ensures keratinocyte survival and efficient wound repair
    • Telorack M, Meyer M, Ingold I, Conrad M, Bloch W, Werner S. A glutathione–Nrf2–thioredoxin cross-talk ensures keratinocyte survival and efficient wound repair. PLoS Genet 2016;12:e1005800.
    • (2016) PLoS Genet , vol.12
    • Telorack, M.1    Meyer, M.2    Ingold, I.3    Conrad, M.4    Bloch, W.5    Werner, S.6
  • 20
    • 84901323900 scopus 로고    scopus 로고
    • Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis
    • Dixon SJ, Patel DN, Welsch M, Skouta R, Lee ED, Hayano M, et al. Pharmacological inhibition of cystine-glutamate exchange induces endoplasmic reticulum stress and ferroptosis. Elife 2014;3:e02523.
    • (2014) Elife , vol.3
    • Dixon, S.J.1    Patel, D.N.2    Welsch, M.3    Skouta, R.4    Lee, E.D.5    Hayano, M.6
  • 21
    • 84926387317 scopus 로고    scopus 로고
    • Ferroptosis as a p53-mediated activity during tumour suppression
    • Jiang L, Kon N, Li T, Wang SJ, Su T, Hibshoosh H, et al. Ferroptosis as a p53-mediated activity during tumour suppression. Nature 2015;520:57-62.
    • (2015) Nature , vol.520 , pp. 57-62
    • Jiang, L.1    Kon, N.2    Li, T.3    Wang, S.J.4    Su, T.5    Hibshoosh, H.6
  • 22
    • 85004093132 scopus 로고    scopus 로고
    • Acetylation is crucial for p53-mediated ferroptosis and tumor suppression
    • Wang SJ, Li D, Ou Y, Jiang L, Chen Y, Zhao Y, et al. Acetylation is crucial for p53-mediated ferroptosis and tumor suppression. Cell Rep 2016;17:366-373.
    • (2016) Cell Rep , vol.17 , pp. 366-373
    • Wang, S.J.1    Li, D.2    Ou, Y.3    Jiang, L.4    Chen, Y.5    Zhao, Y.6
  • 25
    • 0037847496 scopus 로고    scopus 로고
    • Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis
    • Nicolas G, Viatte L, Lou DQ, Bennoun M, Beaumont C, Kahn A, et al. Constitutive hepcidin expression prevents iron overload in a mouse model of hemochromatosis. Nat Genet 2003;34:97-101.
    • (2003) Nat Genet , vol.34 , pp. 97-101
    • Nicolas, G.1    Viatte, L.2    Lou, D.Q.3    Bennoun, M.4    Beaumont, C.5    Kahn, A.6
  • 26
    • 33644876815 scopus 로고    scopus 로고
    • A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression
    • Wang RH, Li C, Xu X, Zheng Y, Xiao C, Zerfas P, et al. A role of SMAD4 in iron metabolism through the positive regulation of hepcidin expression. Cell Metab 2005;2:399-409.
    • (2005) Cell Metab , vol.2 , pp. 399-409
    • Wang, R.H.1    Li, C.2    Xu, X.3    Zheng, Y.4    Xiao, C.5    Zerfas, P.6
  • 27
    • 84865565820 scopus 로고    scopus 로고
    • Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice
    • Zhang Z, Zhang F, Guo X, An P, Tao Y, Wang F. Ferroportin1 in hepatocytes and macrophages is required for the efficient mobilization of body iron stores in mice. Hepatology 2012;56:961-971.
    • (2012) Hepatology , vol.56 , pp. 961-971
    • Zhang, Z.1    Zhang, F.2    Guo, X.3    An, P.4    Tao, Y.5    Wang, F.6
  • 28
    • 80051895753 scopus 로고    scopus 로고
    • Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses
    • Zhang Z, Zhang F, An P, Guo X, Shen Y, Tao Y, et al. Ferroportin1 deficiency in mouse macrophages impairs iron homeostasis and inflammatory responses. Blood 2011;118:1912-1922.
    • (2011) Blood , vol.118 , pp. 1912-1922
    • Zhang, Z.1    Zhang, F.2    An, P.3    Guo, X.4    Shen, Y.5    Tao, Y.6
  • 29
  • 30
    • 84864376907 scopus 로고    scopus 로고
    • Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice
    • Delima RD, Chua AC, Tirnitz-Parker JE, Gan EK, Croft KD, Graham RM, et al. Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice. Hepatology 2012;56:585-593.
    • (2012) Hepatology , vol.56 , pp. 585-593
    • Delima, R.D.1    Chua, A.C.2    Tirnitz-Parker, J.E.3    Gan, E.K.4    Croft, K.D.5    Graham, R.M.6
  • 32
    • 0033034614 scopus 로고    scopus 로고
    • Dietary iron overload inhibits carbon tetrachloride–induced promotion in chemical hepatocarcinogenesis: effects on cell proliferation, apoptosis, and antioxidation
    • Wang GS, Eriksson LC, Xia L, Olsson J, Stal P. Dietary iron overload inhibits carbon tetrachloride–induced promotion in chemical hepatocarcinogenesis: effects on cell proliferation, apoptosis, and antioxidation. J Hepatol 1999;30:689-698.
    • (1999) J Hepatol , vol.30 , pp. 689-698
    • Wang, G.S.1    Eriksson, L.C.2    Xia, L.3    Olsson, J.4    Stal, P.5
  • 33
    • 84906307881 scopus 로고    scopus 로고
    • Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload
    • Lunova M, Goehring C, Kuscuoglu D, Mueller K, Chen Y, Walther P, et al. Hepcidin knockout mice fed with iron-rich diet develop chronic liver injury and liver fibrosis due to lysosomal iron overload. J Hepatol 2014;61:633-641.
    • (2014) J Hepatol , vol.61 , pp. 633-641
    • Lunova, M.1    Goehring, C.2    Kuscuoglu, D.3    Mueller, K.4    Chen, Y.5    Walther, P.6
  • 34
    • 84976292806 scopus 로고    scopus 로고
    • Autophagy promotes ferroptosis by degradation of ferritin
    • Hou W, Xie Y, Song X, Sun X, Lotze MT, Zeh HJ 3rd, et al. Autophagy promotes ferroptosis by degradation of ferritin. Autophagy 2016;12:1425-1428.
    • (2016) Autophagy , vol.12 , pp. 1425-1428
    • Hou, W.1    Xie, Y.2    Song, X.3    Sun, X.4    Lotze, M.T.5    Zeh, H.J.6
  • 35
    • 84906054877 scopus 로고    scopus 로고
    • Nrf2- and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition
    • Ye P, Mimura J, Okada T, Sato H, Liu T, Maruyama A, et al. Nrf2- and ATF4-dependent upregulation of xCT modulates the sensitivity of T24 bladder carcinoma cells to proteasome inhibition. Mol Cell Biol 2014;34:3421-3434.
    • (2014) Mol Cell Biol , vol.34 , pp. 3421-3434
    • Ye, P.1    Mimura, J.2    Okada, T.3    Sato, H.4    Liu, T.5    Maruyama, A.6
  • 36
    • 79951906200 scopus 로고    scopus 로고
    • Thiol-based redox switches and gene regulation
    • Antelmann H, Helmann JD. Thiol-based redox switches and gene regulation. Antioxid Redox Signal 2011;14:1049-1063.
    • (2011) Antioxid Redox Signal , vol.14 , pp. 1049-1063
    • Antelmann, H.1    Helmann, J.D.2
  • 37
    • 34250372956 scopus 로고    scopus 로고
    • RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels
    • Yagoda N, von Rechenberg M, Zaganjor E, Bauer AJ, Yang WS, Fridman DJ, et al. RAS–RAF–MEK-dependent oxidative cell death involving voltage-dependent anion channels. Nature 2007;447:864-868.
    • (2007) Nature , vol.447 , pp. 864-868
    • Yagoda, N.1    von Rechenberg, M.2    Zaganjor, E.3    Bauer, A.J.4    Yang, W.S.5    Fridman, D.J.6
  • 38
    • 85024121807 scopus 로고    scopus 로고
    • The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents
    • Yu Y, Xie Y, Cao L, Yang L, Yang M, Lotze MT, et al. The ferroptosis inducer erastin enhances sensitivity of acute myeloid leukemia cells to chemotherapeutic agents. Mol Cell Oncol 2015;2:e1054549.
    • (2015) Mol Cell Oncol , vol.2
    • Yu, Y.1    Xie, Y.2    Cao, L.3    Yang, L.4    Yang, M.5    Lotze, M.T.6
  • 40
    • 35848967804 scopus 로고    scopus 로고
    • How to interpret LC3 immunoblotting
    • Mizushima N, Yoshimori T. How to interpret LC3 immunoblotting. Autophagy 2007;3:542-545.
    • (2007) Autophagy , vol.3 , pp. 542-545
    • Mizushima, N.1    Yoshimori, T.2
  • 43
    • 84899008557 scopus 로고    scopus 로고
    • Cysteine oxidation reactions catalyzed by a mononuclear non-heme iron enzyme (OvoA) in ovothiol biosynthesis
    • Song H, Her AS, Raso F, Zhen Z, Huo Y, Liu P. Cysteine oxidation reactions catalyzed by a mononuclear non-heme iron enzyme (OvoA) in ovothiol biosynthesis. Org Lett 2014;16:2122-2125.
    • (2014) Org Lett , vol.16 , pp. 2122-2125
    • Song, H.1    Her, A.S.2    Raso, F.3    Zhen, Z.4    Huo, Y.5    Liu, P.6
  • 44
    • 79958199304 scopus 로고    scopus 로고
    • Do genetic variations in antioxidant enzymes influence the course of hereditary hemochromatosis?
    • Nahon P, Sutton A, Pessayre D, Rufat P, Charnaux N, Trinchet JC, et al. Do genetic variations in antioxidant enzymes influence the course of hereditary hemochromatosis? Antioxid Redox Signal 2011;15:31-38.
    • (2011) Antioxid Redox Signal , vol.15 , pp. 31-38
    • Nahon, P.1    Sutton, A.2    Pessayre, D.3    Rufat, P.4    Charnaux, N.5    Trinchet, J.C.6
  • 47
    • 84885378901 scopus 로고    scopus 로고
    • Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target
    • Timmerman LA, Holton T, Yuneva M, Louie RJ, Padro M, Daemen A, et al. Glutamine sensitivity analysis identifies the xCT antiporter as a common triple-negative breast tumor therapeutic target. Cancer Cell 2013;24:450-465.
    • (2013) Cancer Cell , vol.24 , pp. 450-465
    • Timmerman, L.A.1    Holton, T.2    Yuneva, M.3    Louie, R.J.4    Padro, M.5    Daemen, A.6


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