Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression

Cell Reports

Volumn 17, Issue 2, 2016, Pages 366-373

  Wang, Shang Jui ^a   Li, Dawei ^a   Ou, Yang ^a   Jiang, Le ^a   Chen, Yue ^b,c   Zhao, Yingming ^b   Gu, Wei ^a  

^a Columbia University ^*  (United States)

^b UNIVERSITY OF CHICAGO   (United States)

^c UNIVERSITY OF MINNESOTA   (United States)

Author keywords

acetylation; deacetylation; ferroptosis; metabolic regulation; p53; SLC7A11; transcription; tumor suppression

Indexed keywords

LYSINE; PROTEIN MDM2; PROTEIN P53; REGULATOR PROTEIN; SLC7A11 PROTEIN; TIGAR PROTEIN; UNCLASSIFIED DRUG; AMINO ACID TRANSPORTER; C12ORF5 PROTEIN, HUMAN; SIGNAL PEPTIDE; SLC7A11 PROTEIN, HUMAN;

ACETYLATION; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER INHIBITION; CELL DEATH; CONTROLLED STUDY; FERROPTOSIS; GENE MUTATION; HUMAN; HUMAN CELL; METABOLISM; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; TRANSACTIVATION; TUMOR XENOGRAFT; ANIMAL; APOPTOSIS; CELL CYCLE CHECKPOINT; DRUG SCREENING; GENETICS; LUNG TUMOR; MUTATION; PATHOLOGY;

ACETYLATION; AMINO ACID TRANSPORT SYSTEM Y+; ANIMALS; APOPTOSIS; CELL CYCLE CHECKPOINTS; HUMANS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; LUNG NEOPLASMS; MICE; MUTATION; PROTO-ONCOGENE PROTEINS C-MDM2; TUMOR SUPPRESSOR PROTEIN P53; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 85004093132     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.09.022     Document Type: Article

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