A Glutathione-Nrf2-Thioredoxin Cross-Talk Ensures Keratinocyte Survival and Efficient Wound Repair

PLoS Genetics

Volumn 12, Issue 1, 2016, Pages

  Telorack, Michèle ^a   Meyer, Michael ^a   Ingold, Irina ^b   Conrad, Marcus ^b   Bloch, Wilhelm ^c   Werner, Sabine ^a  

^a ETH ZURICH   (Switzerland)

^b INSTITUTE OF EPIDEMIOLOGY   (Germany)

^c GERMAN SPORT UNIVERSITY COLOGNE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN METABOLITE; THIOREDOXIN; TRANSCRIPTION FACTOR NRF2; ANTIOXIDANT; NFE2L2 PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL GENETICS; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; BIOSYNTHESIS; CATALYSIS; CELL DAMAGE; CELL DIFFERENTIATION; CELL FUNCTION; CELL PROLIFERATION; CELL PROTECTION; CELL STRUCTURE; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; EPIDERMIS CELL; FEMALE; FERROPTOSIS; HISTOPATHOLOGY; HYPERKERATOSIS; IN VITRO STUDY; IN VIVO STUDY; KERATINOCYTE; LIPID PEROXIDATION; MALE; MOLECULAR INTERACTION; MOUSE; NECROPTOSIS; NONHUMAN; PROTEIN DEFICIENCY; PROTEIN DEPLETION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; WOUND HEALING; ANIMAL; DEFICIENCY; GENETICS; METABOLISM; OXIDATIVE STRESS; PATHOLOGY; SKIN;

ANIMALS; ANTIOXIDANTS; APOPTOSIS; CELL SURVIVAL; DNA DAMAGE; GLUTAMATE-CYSTEINE LIGASE; GLUTATHIONE; KERATINOCYTES; MICE; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; SKIN; THIOREDOXINS; WOUND HEALING;

EID: 84958729887     PISSN: 15537390     EISSN: 15537404     Source Type: Journal    
DOI: 10.1371/journal.pgen.1005800     Document Type: Article

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