An Atomic Structure of the Human Spliceosome

Cell

Volumn 169, Issue 5, 2017, Pages 918-929.e14

  Zhang, Xiaofeng ^a   Yan, Chuangye ^a   Hang, Jing ^a   Finci, Lorenzo I ^a   Lei, Jianlin ^a   Shi, Yigong ^a  

^a TSINGHUA UNIVERSITY   (China)

Author keywords

atomic structure; C complex; cryo EM; EJC; exon junction complex; exon ligation; human spliceosome; pre mRNA splicing; step 2 factors; step II activated spliceosome

Indexed keywords

ADENOSINE TRIPHOSPHATASE; HELICASE; SMALL NUCLEAR RIBONUCLEOPROTEIN; DEAD BOX PROTEIN; DHX8 PROTEIN, HUMAN; PRKRIP1 PROTEIN, HUMAN; RBM22 PROTEIN, HUMAN; RNA BINDING PROTEIN; RNA PRECURSOR; RNA SPLICING FACTOR;

ARTICLE; CELL DENSITY; CONTROLLED STUDY; ELECTRON MICROSCOPY; EXON; HELA CELL LINE; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRON; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN STRUCTURE; RNA BINDING; SACCHAROMYCES CEREVISIAE; SPLICEOSOME; CHEMISTRY; CRYOELECTRON MICROSCOPY; METABOLISM; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; RNA SPLICING; ULTRASTRUCTURE;

BASE SEQUENCE; CRYOELECTRON MICROSCOPY; DEAD-BOX RNA HELICASES; EXONS; HUMANS; INTRONS; MODELS, MOLECULAR; RNA PRECURSORS; RNA SPLICING; RNA SPLICING FACTORS; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE; SPLICEOSOMES;

EID: 85019070009     PISSN: 00928674     EISSN: 10974172     Source Type: Journal    
DOI: 10.1016/j.cell.2017.04.033     Document Type: Article

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