Cryo-EM structure of the spliceosome immediately after branching

Nature

Volumn 537, Issue 7619, 2016, Pages 197-201

  Galej, Wojciech P ^a   Wilkinson, Max E ^a   Fica, Sebastian M ^a   Oubridge, Chris ^a   Newman, Andrew J ^a   Nagai, Kiyoshi ^a  

^a MRC LABORATORY OF MOLECULAR BIOLOGY   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ADENOSINE; FUNGAL RNA; MAGNESIUM; MESSENGER RNA PRECURSOR; NUCLEOTIDE; NUCLEOTIDE G; PRP16 HELICASE; PRP8 REVERSE TRANSCRIPTASE; RIBOZYME; RNA DIRECTED DNA POLYMERASE; RNA HELICASE; SMALL NUCLEAR RNA; UNCLASSIFIED DRUG; ADENOSINE TRIPHOSPHATASE; CWC25 PROTEIN, S CEREVISIAE; NUCLEAR PROTEIN; PRP16 PROTEIN, S CEREVISIAE; PRP8 PROTEIN, S CEREVISIAE; RNA PRECURSOR; RNA SPLICING; RNA SPLICING FACTOR; SACCHAROMYCES CEREVISIAE PROTEIN; SMALL NUCLEAR RIBONUCLEOPROTEIN; U2 SMALL NUCLEAR RNA; U5 SMALL NUCLEAR RNA; U6 SMALL NUCLEAR RNA; YJU2 PROTEIN, S CEREVISIAE;

AMINO ACID; CATALYSIS; CHEMICAL BINDING; ENZYME ACTIVITY; GENE EXPRESSION; GENETIC MARKER; PROTEIN; RNA;

5' UNTRANSLATED REGION; AMINO TERMINAL SEQUENCE; ARTICLE; CATALYSIS; COMPARATIVE STUDY; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; CRYOELECTRON MICROSCOPY; EXON; INTRON; MOLECULAR DOCKING; NONHUMAN; NUCLEOTIDE BINDING SITE; PRIORITY JOURNAL; RNA ANALYSIS; RNA CLEAVAGE; RNA SEQUENCE; RNA STRUCTURE; SACCHAROMYCES CEREVISIAE; SPLICEOSOME; TRANSESTERIFICATION; BASE PAIRING; CHEMISTRY; ENZYME ACTIVE SITE; ESTERIFICATION; GENETICS; METABOLISM; MOLECULAR MODEL; NUCLEOTIDE SEQUENCE; RNA SPLICING; ULTRASTRUCTURE;

RUMEX;

ADENOSINE; ADENOSINE TRIPHOSPHATASES; BASE PAIRING; BASE SEQUENCE; CATALYTIC DOMAIN; CRYOELECTRON MICROSCOPY; ESTERIFICATION; EXONS; INTRONS; MAGNESIUM; MODELS, MOLECULAR; NUCLEAR PROTEINS; RIBONUCLEOPROTEIN, U4-U6 SMALL NUCLEAR; RIBONUCLEOPROTEIN, U5 SMALL NUCLEAR; RNA HELICASES; RNA PRECURSORS; RNA SPLICE SITES; RNA SPLICING; RNA SPLICING FACTORS; RNA, FUNGAL; RNA, SMALL NUCLEAR; SACCHAROMYCES CEREVISIAE; SACCHAROMYCES CEREVISIAE PROTEINS; SPLICEOSOMES;

EID: 84986612633     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature19316     Document Type: Article

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