-
1
-
-
84874894377
-
Microfabricated mammalian organ systems and their integration into models of whole animals and humans
-
Sung, J. H., Esch, M. B., Prot, J.-M., Long, C. J., et al., "Microfabricated mammalian organ systems and their integration into models of whole animals and humans," Lab on a Chip 13, 1201-1212 (2013).
-
Lab on A Chip
, vol.13
, Issue.2013
, pp. 1201-1212
-
-
Sung, H.J.1
Esch, B.M.2
Prot, J.-M.3
Long, J.C.4
-
2
-
-
84940491425
-
Microfluidic organ-on-a-chip technology for advancement of drug development and toxicology
-
Caplin, J. D., Granados, N. G., James, M. R., Montazami, R., et al., "Microfluidic Organ-on-a-Chip Technology for Advancement of Drug Development and Toxicology," Advanced Healthcare Materials 4, 1426-1450 (2015).
-
(2015)
Advanced Healthcare Materials
, vol.4
, pp. 1426-1450
-
-
Caplin, D.J.1
Granados, G.N.2
James, R.M.3
Montazami, R.4
-
3
-
-
84901946024
-
Lessons learned from the fate of AstraZeneca's drug pipeline: A five-dimensional framework
-
Cook, D., Brown, D., Alexander, R., March, R., et al., "Lessons learned from the fate of AstraZeneca's drug pipeline: a five-dimensional framework," Nat Rev Drug Discov 13, 419-31 (2014).
-
(2014)
Nat Rev Drug Discov
, vol.13
, pp. 419-431
-
-
Cook, D.1
Brown, D.2
Alexander, R.3
March, R.4
-
4
-
-
84878930738
-
Progression of NAFLD to diabetes mellitus, cardiovascular disease, or cirrhosis
-
Anstee, Q., Targher, G. and Day, C., "Progression of NAFLD to diabetes mellitus, cardiovascular disease, or cirrhosis," Nat Rev Gastroenterol Hepatol 10, 330-344 (2013).
-
(2013)
Nat Rev Gastroenterol Hepatol
, vol.10
, pp. 330-344
-
-
Anstee, Q.1
Targher, G.2
Day, C.3
-
5
-
-
85017106465
-
Nonalcoholic fatty liver disease
-
Brunt, E. M., Wong, V. W., Nobili, V., Day, C. P., et al., "Nonalcoholic fatty liver disease," Nat Rev Dis Primers 1, 15080 (2015).
-
(2015)
Nat Rev Dis Primers
, vol.1
, pp. 15080
-
-
Brunt, M.E.1
Wong, W.V.2
Nobili, V.3
Day, P.C.4
-
6
-
-
84994247083
-
Nonalcoholic steatohepatitis (NASH) drugs market
-
Cassidy, S. and Syed, B. A., "Nonalcoholic steatohepatitis (NASH) drugs market," Nat Rev Drug Discov 15, 745-746 (2016).
-
(2016)
Nat Rev Drug Discov
, vol.15
, pp. 745-746
-
-
Cassidy, S.1
Syed, A.B.2
-
7
-
-
84891696888
-
Prevention of diabetes with pioglitazone in act now physiologic correlates
-
DeFronzo, R., Tripathy, D., Schwenke, D., Banerji, M., et al., "Prevention of Diabetes With Pioglitazone in ACT NOW Physiologic Correlates," Diabetes 62, 3920-3926 (2013).
-
(2013)
Diabetes
, vol.62
, pp. 3920-3926
-
-
DeFronzo, R.1
Tripathy, D.2
Schwenke, D.3
Banerji, M.4
-
8
-
-
35148856230
-
Treatment update: Thiazolidinediones in combination with metformin for the treatment of type 2 diabetes
-
Stafford, J. and Elasy, T., "Treatment update: thiazolidinediones in combination with metformin for the treatment of type 2 diabetes," VascHealth Risk Management 3, 503-510 (2007).
-
(2007)
VascHealth Risk Management
, vol.3
, pp. 503-510
-
-
Stafford, J.1
Elasy, T.2
-
9
-
-
84899105340
-
Endometriosis: Pathogenesis and treatment
-
Vercellini, P., Vigano, P., Somigliana, E. and Fedele, L., "Endometriosis: pathogenesis and treatment," Nature Publishing Group 10, 261-275 (2013).
-
(2013)
Nature Publishing Group
, vol.10
, pp. 261-275
-
-
Vercellini, P.1
Vigano, P.2
Somigliana, E.3
Fedele, L.4
-
10
-
-
84865687623
-
The pathophysiology of uterine adenomyosis: An update
-
Benagiano, G., Habiba, M., Brosens, I., Habiba, M., et al., "The pathophysiology of uterine adenomyosis: An update," Fertility and Sterility 98, 572-579 (2012).
-
(2012)
Fertility and Sterility
, vol.98
, pp. 572-579
-
-
Benagiano, G.1
Habiba, M.2
Brosens, I.3
Habiba, M.4
-
11
-
-
84893844348
-
Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation
-
Beste, M. T., Pfäffle-Doyle, N., Prentice, E. A., Morris, S. N., et al., "Molecular network analysis of endometriosis reveals a role for c-Jun-regulated macrophage activation.," Science Translational Medicine 6, 222ra16 (2014).
-
(2014)
Science Translational Medicine
, vol.6
, pp. 222ra16
-
-
Beste, T.M.1
Pfäffle-Doyle, N.2
Prentice, A.E.3
Morris, N.S.4
-
12
-
-
53649097541
-
Anti-TNF-alpha treatment for deep endometriosis-associated pain: A randomized placebo-controlled trial
-
Koninckx, P. R., Craessaerts, M., Timmerman, D., Cornillie, F., et al., "Anti-TNF-alpha treatment for deep endometriosis-associated pain: a randomized placebo-controlled trial," Hum Reprod 23, 2017-23 (2008).
-
(2008)
Hum Reprod
, vol.23
, pp. 2017-2023
-
-
Koninckx, R.P.1
Craessaerts, M.2
Timmerman, D.3
Cornillie, F.4
-
13
-
-
84959474195
-
C-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: An assessor-blind placebo-controlled randomized study
-
Hussein, M., Chai, D. C., Kyama, C. M., Mwenda, J. M., et al., "c-Jun NH2-terminal kinase inhibitor bentamapimod reduces induced endometriosis in baboons: an assessor-blind placebo-controlled randomized study," Fertil Steril 105, 815-24 e5 (2016).
-
(2016)
Fertil Steril
, vol.105
, pp. 815-824e5
-
-
Hussein, M.1
Chai, C.D.2
Kyama, M.C.3
Mwenda, M.J.4
-
14
-
-
30344461318
-
Recombinant human TNFRSF1A (r-hTBP1) inhibits the development of endometriosis in baboons: A prospective, randomized, placebo-and drug-controlled study
-
D'Hooghe, T. M., Nugent, N. P., Cuneo, S., Chai, D. C., et al., "Recombinant human TNFRSF1A (r-hTBP1) inhibits the development of endometriosis in baboons: a prospective, randomized, placebo-and drug-controlled study," Biol Reprod 74, 131-6 (2006).
-
(2006)
Biol Reprod
, vol.74
, pp. 131-136
-
-
D'Hooghe, M.T.1
Nugent, P.N.2
Cuneo, S.3
Chai, C.D.4
-
15
-
-
42449085424
-
Tumor necrosis factor-alpha regulates inflammatory and mesenchymal responses via mitogen-activated protein kinase kinase, p38, and nuclear factor kappaB in human endometriotic epithelial cells
-
Grund, E. M., Kagan, D., Tran, C. A., Zeitvogel, A., et al., "Tumor necrosis factor-alpha regulates inflammatory and mesenchymal responses via mitogen-activated protein kinase kinase, p38, and nuclear factor kappaB in human endometriotic epithelial cells," Mol Pharmacol 73, 1394-404 (2008).
-
(2008)
Mol Pharmacol
, vol.73
, pp. 1394-1404
-
-
Grund, M.E.1
Kagan, D.2
Tran, A.C.3
Zeitvogel, A.4
-
16
-
-
84992453957
-
Modeling fatty liver disease in animals: Is there an optimal approach, and is the effort worthwhile
-
Maher, J. J., "Modeling fatty liver disease in animals: Is there an optimal approach, and is the effort worthwhile," Hepatology 64, 1398-1400 (2016).
-
(2016)
Hepatology
, vol.64
, pp. 1398-1400
-
-
Maher, J.J.1
-
17
-
-
84992391872
-
Integrated network analysis reveals an association between plasma mannose levels and insulin resistance
-
Lee, S., Zhang, C., Kilicarslan, M., Piening, B. D., et al., "Integrated Network Analysis Reveals an Association between Plasma Mannose Levels and Insulin Resistance," Cell Metab 24, 172-84 (2016).
-
(2016)
Cell Metab
, vol.24
, pp. 172-184
-
-
Lee, S.1
Zhang, C.2
Kilicarslan, M.3
Piening, D.B.4
-
18
-
-
84951905513
-
Th17 cytokines differentiate obesity from obesityassociated type 2 diabetes and promote TNFalpha production
-
Ip, B., Cilfone, N. A., Belkina, A. C., DeFuria, J., et al., "Th17 cytokines differentiate obesity from obesityassociated type 2 diabetes and promote TNFalpha production," Obesity (Silver Spring) 24, 102-12 (2016).
-
(2016)
Obesity (Silver Spring)
, vol.24
, pp. 102-112
-
-
Ip, B.1
Cilfone, A.N.2
Belkina, C.A.3
DeFuria, J.4
-
19
-
-
84878429096
-
ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling
-
Miller, M. A., Meyer, A. S., Beste, M. T., Lasisi, Z., et al., "ADAM-10 and -17 regulate endometriotic cell migration via concerted ligand and receptor shedding feedback on kinase signaling.," Proceedings of the National Academy of Sciences 110, E2074-E2083 (2013).
-
(2013)
Proceedings of the National Academy of Sciences
, vol.110
, pp. E2074-E2083
-
-
Miller, A.M.1
Meyer, S.A.2
Beste, T.M.3
Lasisi, Z.4
-
20
-
-
76249117193
-
Dioxin and endometrial progesterone resistance
-
Bruner-Tran, K., Ding, T. and Osteen, K., "Dioxin and Endometrial Progesterone Resistance," Semin Reprod Med 28, 059-068 (2010).
-
(2010)
Semin Reprod Med
, vol.28
, pp. 059-068
-
-
Bruner-Tran, K.1
Ding, T.2
Osteen, K.3
-
21
-
-
34547689484
-
Organotropism of breast cancer metastasis
-
Lu, X. and Kang, Y., "Organotropism of breast cancer metastasis," J Mammary Gland Biol Neoplasia 12, 153-62 (2007).
-
(2007)
J Mammary Gland Biol Neoplasia
, vol.12
, pp. 153-162
-
-
Lu, X.1
Kang, Y.2
-
22
-
-
84942629362
-
Targeted therapies for triple-negative breast cancer: Combating a stubborn disease
-
Kalimutho, M., Parsons, K., Mittal, D., Lopez, J. A., et al., "Targeted Therapies for Triple-Negative Breast Cancer: Combating a Stubborn Disease," Trends Pharmacol Sci 36, 822-46 (2015).
-
(2015)
Trends Pharmacol Sci
, vol.36
, pp. 822-846
-
-
Kalimutho, M.1
Parsons, K.2
Mittal, D.3
Lopez, A.J.4
-
23
-
-
84962393746
-
Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance
-
Miller, M. A., Oudin, M. J., Sullivan, R. J., Wang, S. J., et al., "Reduced Proteolytic Shedding of Receptor Tyrosine Kinases Is a Post-Translational Mechanism of Kinase Inhibitor Resistance," Cancer Discov 6, 382-99 (2016).
-
(2016)
Cancer Discov
, vol.6
, pp. 382-399
-
-
Miller, A.M.1
Oudin, J.M.2
Sullivan, J.R.3
Wang, J.S.4
-
24
-
-
84919488684
-
Modeling human carcinomas: Physiologically relevant 3D models to improve anti-cancer drug development
-
Unger, C., Kramer, N., Walzl, A., Scherzer, M., et al., "Modeling human carcinomas: physiologically relevant 3D models to improve anti-cancer drug development," Adv Drug Deliv Rev 79-80, 50-67 (2014).
-
(2014)
Adv Drug Deliv Rev
, vol.79-80
, pp. 50-67
-
-
Unger, C.1
Kramer, N.2
Walzl, A.3
Scherzer, M.4
-
25
-
-
85033690418
-
Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease
-
Press
-
Gilbert, P. and Weaver, V., "Cellular adaptation to biomechanical stress across length scales in tissue homeostasis and disease," Semin Cell Dev Biol. In Press, (2016).
-
(2016)
Semin Cell Dev Biol
-
-
Gilbert, P.1
Weaver, V.2
-
26
-
-
82755189529
-
Live-cell imaging of tumor proteolysis: Impact of cellular and non-cellular microenvironment
-
Rothberg, J. M., Sameni, M., Moin, K. and Sloane, B. F., "Live-cell imaging of tumor proteolysis: impact of cellular and non-cellular microenvironment," Biochim Biophys Acta 1824, 123-32 (2012).
-
(2012)
Biochim Biophys Acta
, vol.1824
, pp. 123-132
-
-
Rothberg, M.J.1
Sameni, M.2
Moin, K.3
Sloane, F.B.4
-
27
-
-
84919650188
-
Microfluidic 3D models of cancer
-
Sung, K. E. and Beebe, D. J., "Microfluidic 3D models of cancer," Adv Drug Deliv Rev 79-80, 68-78 (2014).
-
(2014)
Adv Drug Deliv Rev
, vol.79-80
, pp. 68-78
-
-
Sung, E.K.1
Beebe, J.D.2
-
28
-
-
77954502719
-
Microfluidic culture models of tumor angiogenesis
-
Stroock, A. D. and Fischbach, C., "Microfluidic culture models of tumor angiogenesis," Tissue Engineering Part A 16, 2143-2146 (2010).
-
(2010)
Tissue Engineering Part A
, vol.16
, pp. 2143-2146
-
-
Stroock, D.A.1
Fischbach, C.2
-
29
-
-
84983543822
-
3D microtumors in vitro supported by perfused vascular networks
-
Sobrino, A., Phan, D. T., Datta, R., Wang, X., et al., "3D microtumors in vitro supported by perfused vascular networks," Sci Rep 6, 31589 (2016).
-
(2016)
Sci Rep
, vol.6
, pp. 31589
-
-
Sobrino, A.1
Phan, T.D.2
Datta, R.3
Wang, X.4
-
30
-
-
84953409561
-
Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels
-
Wang, X., Phan, D. T., Sobrino, A., George, S. C., et al., "Engineering anastomosis between living capillary networks and endothelial cell-lined microfluidic channels," Lab Chip 16, 282-90 (2016).
-
(2016)
Lab Chip
, vol.16
, pp. 282-290
-
-
Wang, X.1
Phan, T.D.2
Sobrino, A.3
George, C.S.4
-
31
-
-
84957809952
-
Studying the influence of angiogenesis in in vitro cancer model systems
-
Roudsari, L. C. and West, J. L., "Studying the influence of angiogenesis in in vitro cancer model systems," Adv Drug Deliv Rev 97, 250-9 (2016).
-
(2016)
Adv Drug Deliv Rev
, vol.97
, pp. 250-259
-
-
Roudsari, C.L.1
West, L.J.2
-
32
-
-
84865293346
-
Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function
-
Zervantonakis, I. K., Hughes-Alford, S. K., Charest, J. L., Condeelis, J. S., et al., "Three-dimensional microfluidic model for tumor cell intravasation and endothelial barrier function," Proc Natl Acad Sci U S A 109, 13515-20 (2012).
-
(2012)
Proc Natl Acad Sci U S A
, vol.109
, pp. 13515-13520
-
-
Zervantonakis, K.I.1
Hughes-Alford, K.S.2
Charest, L.J.3
Condeelis, S.J.4
-
33
-
-
84920385055
-
Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation
-
Jeon, J. S., Bersini, S., Gilardi, M., Dubini, G., et al., "Human 3D vascularized organotypic microfluidic assays to study breast cancer cell extravasation," Proc Natl Acad Sci U S A 112, 214-9 (2015).
-
(2015)
Proc Natl Acad Sci U S A
, vol.112
, pp. 214-219
-
-
Jeon, S.J.1
Bersini, S.2
Gilardi, M.3
Dubini, G.4
-
34
-
-
84887983173
-
An estimation of the number of cells in the human body
-
Bianconi, E., Piovesan, A., Facchin, F., Beraudi, A., et al., "An estimation of the number of cells in the human body," Ann Hum Biol 40, 463-71 (2013).
-
(2013)
Ann Hum Biol
, vol.40
, pp. 463-471
-
-
Bianconi, E.1
Piovesan, A.2
Facchin, F.3
Beraudi, A.4
-
35
-
-
84965104188
-
Clusters of circulating tumor cells traverse capillary-sized vessels
-
Au, S. H., Storey, B. D., Moore, J. C., Tang, Q., et al., "Clusters of circulating tumor cells traverse capillary-sized vessels," Proc Natl Acad Sci U S A 113, 4947-52 (2016).
-
(2016)
Proc Natl Acad Sci U S A
, vol.113
, pp. 4947-4952
-
-
Au, H.S.1
Storey, D.B.2
Moore, C.J.3
Tang, Q.4
-
36
-
-
84983356809
-
Liver metastases: Microenvironments and ex-vivo models
-
Clark, A. M., Ma, B., Taylor, D. L., Griffith, L., et al., "Liver metastases: Microenvironments and ex-vivo models," Exp Biol Med (Maywood) 241, 1639-52 (2016).
-
(2016)
Exp Biol Med (Maywood
, vol.241
, pp. 1639-1652
-
-
Clark, M.A.1
Ma, B.2
Taylor, L.D.3
Griffith, L.4
-
37
-
-
84860608896
-
Partial mesenchymal to epithelial reverting transition in breast and prostate cancer metastases
-
Chao, Y., Wu, Q., Acquafondata, M., Dhir, R., et al., "Partial Mesenchymal to Epithelial Reverting Transition in Breast and Prostate Cancer Metastases," Cancer Microenvironment 5, 19-28 (2011).
-
(2011)
Cancer Microenvironment
, vol.5
, pp. 19-28
-
-
Chao, Y.1
Wu, Q.2
Acquafondata, M.3
Dhir, R.4
-
38
-
-
84856013044
-
Hepatocyte induced re-expression of E-cadherin in breast and prostate cancer cells increases chemoresistance
-
Chao, Y., Wu, Q., Shepard, C. and Wells, A., "Hepatocyte induced re-expression of E-cadherin in breast and prostate cancer cells increases chemoresistance," Clin Exp Metastasis 29, 39-50 (2011).
-
(2011)
Clin Exp Metastasis
, vol.29
, pp. 39-50
-
-
Chao, Y.1
Wu, Q.2
Shepard, C.3
Wells, A.4
-
39
-
-
77954304397
-
Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition
-
Chao, Y. L., Shepard, C. R. and Wells, A., "Breast carcinoma cells re-express E-cadherin during mesenchymal to epithelial reverting transition," Mol Cancer 9, 179 (2010).
-
(2010)
Mol Cancer
, vol.9
, pp. 179
-
-
Chao, L.Y.1
Shepard, R.C.2
Wells, A.3
-
40
-
-
18444370256
-
A microfabricated array bioreactor for perfused 3D liver culture
-
Powers, M. J., Domansky, K., Kaazempur-Mofrad, M. R., Kalezi, A., et al., "A microfabricated array bioreactor for perfused 3D liver culture," Biotechnol Bioeng 78, 257-69 (2002).
-
(2002)
Biotechnol Bioeng
, vol.78
, pp. 257-269
-
-
Powers, J.M.1
Domansky, K.2
Kaazempur-Mofrad, R.M.3
Kalezi, A.4
-
41
-
-
77951919817
-
Perfused multiwell plate for 3D liver tissue engineering
-
Domansky, K., Inman, W., Serdy, J., Dash, A., et al., "Perfused multiwell plate for 3D liver tissue engineering," Lab on a Chip 10, 51-58 (2010).
-
(2010)
Lab on A Chip
, vol.10
, pp. 51-58
-
-
Domansky, K.1
Inman, W.2
Serdy, J.3
Dash, A.4
-
42
-
-
84899986727
-
Bioreactor technologies to support liver function in vitro
-
Ebrahimkhani, M. R., Nieman Shepard, J. A., Raredon, M. S. B., Hughes, D. J., et al., "Bioreactor Technologies to Support Liver Function In Vitro," Advanced Drug Delivery Reviews Apr, 132-57 (2014).
-
(2014)
Advanced Drug Delivery Reviews Apr
, pp. 132-157
-
-
Ebrahimkhani, R.M.1
Raredon, B.S.M.2
Hughes, J.D.3
-
43
-
-
84940377180
-
Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor
-
Sarkar, U., Rivera-Burgos, D., Large, E. M., Hughes, D. J., et al., "Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor," Drug Metab Dispos 43, 1091-9 (2015).
-
(2015)
Drug Metab Dispos
, vol.43
, pp. 1091-1099
-
-
Sarkar, U.1
Rivera-Burgos, D.2
Large, M.E.3
Hughes, J.D.4
-
44
-
-
70349399012
-
Liver tissue engineering in the evaluation of drug safety
-
Dash, A., Inman, W., Hoffmaster, K., Sevidal, S., et al., "Liver tissue engineering in the evaluation of drug safety.," Expert Opin Drug Metab Toxicol 5, 1159-1174 (2009).
-
(2009)
Expert Opin Drug Metab Toxicol
, vol.5
, pp. 1159-1174
-
-
Dash, A.1
Inman, W.2
Hoffmaster, K.3
Sevidal, S.4
-
45
-
-
69549135426
-
Biological implications of polydimethylsiloxanebased microfluidic cell culture
-
Regehr, K. J., Domenech, M., Koepsel, J. T., Carver, K. C., et al., "Biological implications of polydimethylsiloxanebased microfluidic cell culture," Lab on a Chip 9, 2132-2139 (2009).
-
(2009)
Lab on A Chip
, vol.9
, pp. 2132-2139
-
-
Regehr, J.K.1
Domenech, M.2
Koepsel, T.J.3
Carver, C.K.4
-
46
-
-
84994896206
-
Modeling therapeutic antibody-small molecule drug-drug interactions using a three dimensional perfusable human liver coculture platform
-
Long, T., Cosgrove, P., Dunn, R. n., Stolz, D., et al., "Modeling Therapeutic Antibody-Small Molecule Drug-Drug Interactions Using a Three Dimensional Perfusable Human Liver Coculture Platform," Drug Metab Dispos 44, 1940-1948 (2016).
-
(2016)
Drug Metab Dispos
, vol.44
, pp. 1940-1948
-
-
Long, T.1
Cosgrove, P.2
Dunn, N.R.3
Stolz, D.4
-
47
-
-
34047159398
-
Novel three-dimensional organotypic liver bioreactor to directly visualize early events in metastatic progression
-
Yates, C., Shepard, C. R., Papworth, G., Dash, A., et al., "Novel three-dimensional organotypic liver bioreactor to directly visualize early events in metastatic progression.," Adv. Cancer Res. 97, 225-246 (2007).
-
(2007)
Adv. Cancer Res
, vol.7
, pp. 225-246
-
-
Yates, C.1
Shepard, R.C.2
Papworth, G.3
Dash, A.4
-
48
-
-
84941740825
-
Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies Technology
-
Usta, O. B., McCarty, W. J., Bale, S., Hegde, M., et al., "Microengineered cell and tissue systems for drug screening and toxicology applications: Evolution of in-vitro liver technologies," Technology (Singap World Sci) 3, 1-26 (2015).
-
(2015)
Singap World Sci
, vol.3
, pp. 1-26
-
-
Usta, B.O.1
McCarty, J.W.2
Bale, S.3
Hegde, M.4
-
49
-
-
84927568897
-
Engineering liver
-
Griffith, L. G., Wells, A. and Stolz, D. B., "Engineering liver," Hepatology 60, 1426-1434 (2014).
-
(2014)
Hepatology
, vol.60
, pp. 1426-1434
-
-
Griffith, G.L.1
Wells, A.2
Stolz, B.D.3
-
50
-
-
85011094658
-
Quantitative assessment of population variability in hepatic drug metabolism using a perfused 3D human liver microphysiological system
-
Tsamandouras, N., Kostrzewski, T., Stokes, C., Griffith, L., et al., "Quantitative assessment of population variability in hepatic drug metabolism using a perfused 3D human liver microphysiological system.," J Pharmacol Exp Ther. 360, 95-105 (2016).
-
(2016)
J Pharmacol Exp Ther
, vol.360
, pp. 95-105
-
-
Tsamandouras, N.1
Kostrzewski, T.2
Stokes, C.3
Griffith, L.4
-
51
-
-
84916918991
-
Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device
-
Vivares, A., Salle-Lefort, S., Arabeyre-Fabre, C., Ngo, R., et al., "Morphological behaviour and metabolic capacity of cryopreserved human primary hepatocytes cultivated in a perfused multiwell device," Xenobiotica 45, 29-44 (2015).
-
(2015)
Xenobiotica
, vol.45
, pp. 29-44
-
-
Vivares, A.1
Salle-Lefort, S.2
Arabeyre-Fabre, C.3
Ngo, R.4
-
52
-
-
84940377180
-
Metabolite profiling and pharmacokinetic evaluation of hydrocortisone in a perfused three-dimensional human liver bioreactor
-
Sarkar, U., Rivera-Burgos, D., Large, E. M., Hughes, D. J., et al., "Metabolite Profiling and Pharmacokinetic Evaluation of Hydrocortisone in a Perfused Three-Dimensional Human Liver Bioreactor," Drug Metab Dispos 43, 1091-1099 (2015).
-
(2015)
Drug Metab Dispos
, vol.43
, pp. 1091-1099
-
-
Sarkar, U.1
Rivera-Burgos, D.2
Large, M.E.3
Hughes, J.D.4
-
53
-
-
85018869297
-
Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease
-
Kostrzewski, T., Cornforth, T., Snow, S., Ouro-Gnao, L., et al., "Three-dimensional perfused human in vitro model of non-alcoholic fatty liver disease," World J Gastroenterol Accepted for publication, (2016).
-
(2016)
World J Gastroenterol Accepted for Publication
-
-
Kostrzewski, T.1
Cornforth, T.2
Snow, S.3
Ouro-Gnao, L.4
-
54
-
-
84927573797
-
Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system
-
Wheeler, S. E., Clark, A. M., Taylor, D. P., Young, C. L., et al., "Spontaneous dormancy of metastatic breast cancer cells in an all human liver microphysiologic system," Br J Cancer 111, 2342-50 (2014).
-
(2014)
Br J Cancer
, vol.111
, pp. 2342-2350
-
-
Wheeler, E.S.1
Clark, M.A.2
Taylor, P.D.3
Young, L.C.4
-
55
-
-
84924066233
-
Photopatterning of Hydrogel Scaffolds Coupled to Filter Materials Using Stereolithography for Perfused 3D Culture of Hepatocytes
-
Neiman, J. A. S., Raman, R., Chan, V., Rhoads, M. G., et al., "Photopatterning of Hydrogel Scaffolds Coupled to Filter Materials Using Stereolithography for Perfused 3D Culture of Hepatocytes," Biotechnology and Bioengineering 112, 777-787 (2015).
-
(2015)
Biotechnology and Bioengineering
, vol.112
, pp. 777-787
-
-
Neiman, S.A.J.1
Raman, R.2
Chan, V.3
Rhoads, G.M.4
-
56
-
-
85006915761
-
A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties
-
Clark, A., Wheeler, S., Young, C., Stockdale, L., et al., "A liver microphysiological system of tumor cell dormancy and inflammatory responsiveness is affected by scaffold properties," Lab Chip 17, 156-168 (2017).
-
(2017)
Lab Chip
, vol.17
, pp. 156-168
-
-
Clark, A.1
Wheeler, S.2
Young, C.3
Stockdale, L.4
-
57
-
-
84859610801
-
Oral exposure to polystyrene nanoparticles affects iron absorption
-
Mahler, G. J., Esch, M. B., Tako, E., Southard, T. L., et al., "Oral exposure to polystyrene nanoparticles affects iron absorption," Nat Nanotechnol 7, 264-71 (2012).
-
(2012)
Nat Nanotechnol
, vol.7
, pp. 264-271
-
-
Mahler, J.G.1
Esch, B.M.2
Tako, E.3
Southard, L.T.4
-
58
-
-
0018856695
-
A colorimetric assay for mucous glycoproteins using Alcian Blue
-
Hall, R., Miller, R., Peatfield, A. and Richardson, P., "A colorimetric assay for mucous glycoproteins using Alcian Blue," Biochem Soc Trans. 8, 72 (1980).
-
(1980)
Biochem Soc Trans
, vol.8
, pp. 72
-
-
Hall, R.1
Miller, R.2
Peatfield, A.3
Richardson, P.4
-
59
-
-
85018921354
-
Integrated gut/liver microphysiological systems platform elucidates inflammatory cytokine/chemokine inter-tissue crosstalk
-
Chen, W. L. K., Edington, C., Suter, E., Yu, J., et al., "Integrated Gut/Liver Microphysiological Systems Platform Elucidates Inflammatory Cytokine/Chemokine Inter-Tissue Crosstalk," Submitted, (2017).
-
(2017)
Submitted
-
-
Chen, K.L.W.1
Edington, C.2
Suter, E.3
Yu, J.4
-
60
-
-
84882252041
-
A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture
-
Wagner, I., Materne, E.-M., Brincker, S., Süßbier, U., et al., "A dynamic multi-organ-chip for long-term cultivation and substance testing proven by 3D human liver and skin tissue co-culture," Lab Chip 13, 3538 (2013).
-
(2013)
Lab Chip
, vol.13
, pp. 3538
-
-
Wagner, I.1
Materne, E.-M.2
Brincker, S.3
Süßbier, U.4
-
61
-
-
84930959624
-
A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents
-
Maschmeyer, I., Lorenz, A. K., Schimek, K., Hasenberg, T., et al., "A four-organ-chip for interconnected long-term co-culture of human intestine, liver, skin and kidney equivalents," Lab Chip 15, 2688-99 (2015).
-
(2015)
Lab Chip
, vol.15
, pp. 2688-2699
-
-
Maschmeyer, I.1
Lorenz, K.A.2
Schimek, K.3
Hasenberg, T.4
-
62
-
-
84859560833
-
Glucose and fatty acid metabolism in a 3 tissue in-vitro model challenged with normo-and hyperglycaemia
-
Iori, E., Vinci, B., Murphy, E., Marescotti, M. C., et al., "Glucose and fatty acid metabolism in a 3 tissue in-vitro model challenged with normo-and hyperglycaemia," PLoS One 7, e34704 (2012).
-
(2012)
PLoS One
, vol.7
, pp. e34704
-
-
Iori, E.1
Vinci, B.2
Murphy, E.3
Marescotti, C.M.4
-
63
-
-
79957583037
-
Metabolic control through hepatocyte and adipose tissue crosstalk in a multicompartmental modular bioreactor
-
Guzzardi, M. A., Domenici, C. and Ahluwalia, A., "Metabolic control through hepatocyte and adipose tissue crosstalk in a multicompartmental modular bioreactor," Tissue Eng Part A 17, 1635-42 (2011).
-
(2011)
Tissue Eng Part A
, vol.17
, pp. 1635-1642
-
-
Guzzardi, A.M.1
Domenici, C.2
Ahluwalia, A.3
-
64
-
-
84991710984
-
The promises of quantitative systems pharmacology modelling for drug development
-
Knight-Schrijver, V. R., Chelliah, V., Cucurull-Sanchez, L. and Le Novere, N., "The promises of quantitative systems pharmacology modelling for drug development," Comput Struct Biotechnol J 14, 363-370 (2016).
-
(2016)
Comput Struct Biotechnol J
, vol.14
, pp. 363-370
-
-
Knight-Schrijver, R.V.1
Chelliah, V.2
Cucurull-Sanchez, L.3
Le Novere, N.4
-
65
-
-
77953809368
-
Dissecting variability in responses to cancer chemotherapy through systems pharmacology
-
Yang, R., Niepel, M., Mitchison, T. K. and Sorger, P. K., "Dissecting variability in responses to cancer chemotherapy through systems pharmacology," Clin Pharmacol Ther 88, 34-8 (2010).
-
(2010)
Clin Pharmacol Ther
, vol.88
, pp. 34-38
-
-
Yang, R.1
Niepel, M.2
Mitchison, K.T.3
Sorger, K.P.4
-
66
-
-
84927592484
-
Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling
-
Abaci, H. E. and Shuler, M. L., "Human-on-a-chip design strategies and principles for physiologically based pharmacokinetics/pharmacodynamics modeling," Integr Biol (Camb) 7, 383-91 (2015).
-
(2015)
Integr Biol (Camb
, vol.7
, pp. 383-391
-
-
Abaci, E.H.1
Shuler, L.M.2
-
67
-
-
84945454098
-
Physiome-on-a-Chip: The Challenge of 'Scaling' in Design, Operation, and Translation of Microphysiological Systems
-
Stokes, C. L., Cirit, M. and Lauffenburger, D. A., "Physiome-on-a-Chip: The Challenge of 'Scaling' in Design, Operation, and Translation of Microphysiological Systems," CPT: Pharmacometrics & Systems Pharmacology 4, 559-562 (2015).
-
(2015)
CPT: Pharmacometrics & Systems Pharmacology
, vol.4
, pp. 559-562
-
-
Stokes, L.C.1
Cirit, M.2
Lauffenburger, A.D.3
-
68
-
-
84945276797
-
Quantitative systems pharmacology approaches applied to microphysiological systems (mps): Data interpretation and multi-mps integration
-
Yu, J., Cilfone, N. A., Large, E. M., Sarkar, U., et al., "Quantitative Systems Pharmacology Approaches Applied to Microphysiological Systems (MPS): Data Interpretation and Multi-MPS Integration," CPT Pharmacometrics Syst. Pharmacol. 4, 585-94 (2015).
-
(2015)
CPT Pharmacometrics Syst. Pharmacol
, vol.4
, pp. 585-594
-
-
Yu, J.1
Cilfone, A.N.2
Large, M.E.3
Sarkar, U.4
|