Physiome-on-a-Chip: The Challenge of "scaling" in Design, Operation, and Translation of Microphysiological Systems

CPT: Pharmacometrics and Systems Pharmacology

Volumn 4, Issue 10, 2015, Pages 559-562

  Stokes, C L ^a   Cirit, M ^b   Lauffenburger, D A ^b  

^a Stokes Consulting   (United States)

^b Massachusetts Institute of Technology Cambridge   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; MICRORNA; PHOSPHOPROTEIN;

ACUTE DISEASE; CELL FUNCTION; CELL MIGRATION; CELL PROLIFERATION; CELL STRUCTURE; CHRONIC DISEASE; CYTOKINE PRODUCTION; DRUG ABSORPTION; DRUG CLEARANCE; DRUG DISTRIBUTION; DRUG ELIMINATION; DRUG EXCRETION; DRUG EXPOSURE; DRUG HALF LIFE; DRUG METABOLISM; ENDOMETRIOSIS; EQUIPMENT DESIGN; FLOW KINETICS; GENERAL DEVICE; HUMAN; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATORY DISEASE; KUPFFER CELL; LIVER CELL; MATHEMATICAL MODEL; METABOLIC RATE; MICROPHYSIOLOGICAL SYSTEM; OXYGEN CONSUMPTION; OXYGEN TRANSPORT; PARTIAL LEAST SQUARES REGRESSION; PHARMACOLOGICAL PARAMETERS; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN FUNCTION; REVIEW; SIGNAL TRANSDUCTION; SURFACE AREA;

EID: 84945454098     PISSN: None     EISSN: 21638306     Source Type: Journal    
DOI: 10.1002/psp4.12042     Document Type: Review

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