메뉴 건너뛰기




Volumn 113, Issue 18, 2016, Pages 4947-4952

Clusters of circulating tumor cells traverse capillary-sized vessels

Author keywords

Cancer metastasis; Capillary microhemodynamics; Circulating tumor cell cluster microemboli; CTC clusters; Microfluidics

Indexed keywords

PACLITAXEL;

EID: 84965104188     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1524448113     Document Type: Article
Times cited : (383)

References (49)
  • 1
    • 79551693066 scopus 로고    scopus 로고
    • Circulating tumor cells: Approaches to isolation and characterization
    • Yu M, Stott S, Toner M, Maheswaran S, Haber DA (2011) Circulating tumor cells: Approaches to isolation and characterization. J Cell Biol 192(3):373-382.
    • (2011) J Cell Biol , vol.192 , Issue.3 , pp. 373-382
    • Yu, M.1    Stott, S.2    Toner, M.3    Maheswaran, S.4    Haber, D.A.5
  • 2
    • 84883152670 scopus 로고    scopus 로고
    • Detecting circulating tumor cells: Current challenges and new trends
    • Hong B, Zu Y (2013) Detecting circulating tumor cells: Current challenges and new trends. Theranostics 3(6):377-394.
    • (2013) Theranostics , vol.3 , Issue.6 , pp. 377-394
    • Hong, B.1    Zu, Y.2
  • 3
    • 84896713649 scopus 로고    scopus 로고
    • Molecular analysis of circulating tumour cells-biology and biomarkers
    • Krebs MG, et al. (2014) Molecular analysis of circulating tumour cells-biology and biomarkers. Nat Rev Clin Oncol 11(3):129-144.
    • (2014) Nat Rev Clin Oncol , vol.11 , Issue.3 , pp. 129-144
    • Krebs, M.G.1
  • 4
    • 34347353063 scopus 로고    scopus 로고
    • Circulating tumor cells (ctc) detection: Clinical impact and future directions
    • Paterlini-Brechot P, Benali NL (2007) Circulating tumor cells (CTC) detection: Clinical impact and future directions. Cancer Lett 253(2):180-204.
    • (2007) Cancer Lett , vol.253 , Issue.2 , pp. 180-204
    • Paterlini-Brechot, P.1    Benali, N.L.2
  • 5
    • 84856862054 scopus 로고    scopus 로고
    • Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer
    • Hou JM, et al. (2012) Clinical significance and molecular characteristics of circulating tumor cells and circulating tumor microemboli in patients with small-cell lung cancer. J Clin Oncol 30(5):525-532.
    • (2012) J Clin Oncol , vol.30 , Issue.5 , pp. 525-532
    • Hou, J.M.1
  • 6
    • 0015603212 scopus 로고
    • The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis
    • Fidler IJ (1973) The relationship of embolic homogeneity, number, size and viability to the incidence of experimental metastasis. Eur J Cancer 9(3):223-227.
    • (1973) Eur J Cancer , vol.9 , Issue.3 , pp. 223-227
    • Fidler, I.J.1
  • 7
    • 0017234894 scopus 로고
    • The significance of hematogenous tumor cell clumps in the metastatic process
    • Liotta LA, Saidel MG, Kleinerman J (1976) The significance of hematogenous tumor cell clumps in the metastatic process. Cancer Res 36(3):889-894.
    • (1976) Cancer Res , vol.36 , Issue.3 , pp. 889-894
    • Liotta, L.A.1    Saidel, M.G.2    Kleinerman, J.3
  • 8
    • 0018141482 scopus 로고
    • Tumor heterogeneity and the biology of cancer invasion and metastasis
    • Fidler IJ (1978) Tumor heterogeneity and the biology of cancer invasion and metastasis. Cancer Res 38(9):2651-2660.
    • (1978) Cancer Res , vol.38 , Issue.9 , pp. 2651-2660
    • Fidler, I.J.1
  • 9
    • 84907342688 scopus 로고    scopus 로고
    • Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis
    • Aceto N, et al. (2014) Circulating tumor cell clusters are oligoclonal precursors of breast cancer metastasis. Cell 158(5):1110-1122.
    • (2014) Cell , vol.158 , Issue.5 , pp. 1110-1122
    • Aceto, N.1
  • 10
    • 79952755005 scopus 로고    scopus 로고
    • Circulating tumor cells as a window on metastasis biology in lung cancer
    • Hou JM, et al. (2011) Circulating tumor cells as a window on metastasis biology in lung cancer. Am J Pathol 178(3):989-996.
    • (2011) Am J Pathol , vol.178 , Issue.3 , pp. 989-996
    • Hou, J.M.1
  • 11
    • 84873811988 scopus 로고    scopus 로고
    • Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition
    • Yu M, et al. (2013) Circulating breast tumor cells exhibit dynamic changes in epithelial and mesenchymal composition. Science 339(6119):580-584.
    • (2013) Science , vol.339 , Issue.6119 , pp. 580-584
    • Yu, M.1
  • 12
    • 84857086516 scopus 로고    scopus 로고
    • Intercellular adhesion: Mechanisms for growth and metastasis of epithelial cancers
    • Balzer EM, Konstantopoulos K (2012) Intercellular adhesion: Mechanisms for growth and metastasis of epithelial cancers. Wiley Interdiscip Rev Syst Biol Med 4(2):171-181.
    • (2012) Wiley Interdiscip Rev Syst Biol Med , vol.4 , Issue.2 , pp. 171-181
    • Balzer, E.M.1    Konstantopoulos, K.2
  • 13
    • 84905814502 scopus 로고    scopus 로고
    • Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer
    • Carlsson A, et al. (2014) Circulating tumor microemboli diagnostics for patients with non-small-cell lung cancer. J Thorac Oncol 9(8):1111-1119.
    • (2014) J Thorac Oncol , vol.9 , Issue.8 , pp. 1111-1119
    • Carlsson, A.1
  • 14
    • 84904121066 scopus 로고    scopus 로고
    • Cancer therapy ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility
    • Yu M, et al. (2014) Cancer therapy. Ex vivo culture of circulating breast tumor cells for individualized testing of drug susceptibility. Science 345(6193):216-220.
    • (2014) Science , vol.345 , Issue.6193 , pp. 216-220
    • Yu, M.1
  • 15
    • 79953147370 scopus 로고    scopus 로고
    • A perspective on cancer cell metastasis
    • Chaffer CL, Weinberg RA (2011) A perspective on cancer cell metastasis. Science 331(6024):1559-1564.
    • (2011) Science , vol.331 , Issue.6024 , pp. 1559-1564
    • Chaffer, C.L.1    Weinberg, R.A.2
  • 16
    • 0023195679 scopus 로고
    • The hemodynamic destruction of circulating cancer cells
    • Weiss L (1987) The hemodynamic destruction of circulating cancer cells. Biorheology 24(2):105-115.
    • (1987) Biorheology , vol.24 , Issue.2 , pp. 105-115
    • Weiss, L.1
  • 17
    • 0035678088 scopus 로고    scopus 로고
    • Circulating tumor cell clusters in the peripheral blood of colorectal cancer patients
    • Molnar B, Ladanyi A, Tanko L, Sréter L, Tulassay Z (2001) Circulating tumor cell clusters in the peripheral blood of colorectal cancer patients. Clin Cancer Res 7(12):4080-4085.
    • (2001) Clin Cancer Res , vol.7 , Issue.12 , pp. 4080-4085
    • Molnar, B.1    Ladanyi, A.2    Tanko, L.3    Sréter, L.4    Tulassay, Z.5
  • 18
    • 84856948692 scopus 로고    scopus 로고
    • Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors
    • Cho EH, et al. (2012) Characterization of circulating tumor cell aggregates identified in patients with epithelial tumors. Phys Biol 9(1):016001.
    • (2012) Phys Biol , vol.9 , Issue.1 , pp. 016001
    • Cho, E.H.1
  • 19
    • 84965163972 scopus 로고    scopus 로고
    • Molecular features and clinical relevance of circulating tumor cells (ctc) and circulating tumor microemboli (ctm in patients with small cell lung cancer (sclc)
    • Hou JM, et al. (2011) Molecular features and clinical relevance of circulating tumor cells (CTC) and circulating tumor microemboli (CTM) in patients with small cell lung cancer (SCLC). Clin Exp Metastasis 28(2):221-222.
    • (2011) Clin Exp Metastasis , vol.28 , Issue.2 , pp. 221-222
    • Hou, J.M.1
  • 20
    • 0001647641 scopus 로고
    • Transpulmonary passage of tumor cell emboli
    • Zeidman I, Buss JM (1952) Transpulmonary passage of tumor cell emboli. Cancer Res 12(10):731-733.
    • (1952) Cancer Res , vol.12 , Issue.10 , pp. 731-733
    • Zeidman, I.1    Buss, J.M.2
  • 21
    • 0013939204 scopus 로고
    • Elastic environment of the capillary bed
    • Fung YC, Zweifach BW, Intaglietta M (1966) Elastic environment of the capillary bed. Circ Res 19(2):441-461.
    • (1966) Circ Res , vol.19 , Issue.2 , pp. 441-461
    • Fung, Y.C.1    Zweifach, B.W.2    Intaglietta, M.3
  • 23
    • 84877341440 scopus 로고    scopus 로고
    • Characterizing deformability and surface friction of cancer cells
    • Byun S, et al. (2013) Characterizing deformability and surface friction of cancer cells. Proc Natl Acad Sci USA 110(19):7580-7585.
    • (2013) Proc Natl Acad Sci USA , vol.110 , Issue.19 , pp. 7580-7585
    • Byun, S.1
  • 24
    • 0036788591 scopus 로고    scopus 로고
    • Neutrophil transit times through pulmonary capillaries: The effects of capillary geometry and fmlp-stimulation
    • Bathe M, Shirai A, Doerschuk CM, Kamm RD (2002) Neutrophil transit times through pulmonary capillaries: The effects of capillary geometry and fMLP-stimulation. Biophys J 83(4):1917-1933.
    • (2002) Biophys J , vol.83 , Issue.4 , pp. 1917-1933
    • Bathe, M.1    Shirai, A.2    Doerschuk, C.M.3    Kamm, R.D.4
  • 25
    • 84906933893 scopus 로고    scopus 로고
    • Nuclear deformability constitutes a rate-limiting step during cell migration in 3-d environments
    • Davidson PM, Denais C, Bakshi MC, Lammerding J (2014) Nuclear deformability constitutes a rate-limiting step during cell migration in 3-D environments. Cell Mol Bioeng 7(3):293-306.
    • (2014) Cell Mol Bioeng , vol.7 , Issue.3 , pp. 293-306
    • Davidson, P.M.1    Denais, C.2    Bakshi, M.C.3    Lammerding, J.4
  • 26
    • 84895746552 scopus 로고    scopus 로고
    • Nuclear lamin stiffness is a barrier to 3d migration, but softness can limit survival
    • Harada T, et al. (2014) Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival. J Cell Biol 204(5):669-682.
    • (2014) J Cell Biol , vol.204 , Issue.5 , pp. 669-682
    • Harada, T.1
  • 27
    • 80052220146 scopus 로고    scopus 로고
    • Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells
    • Chen J, et al. (2011) Classification of cell types using a microfluidic device for mechanical and electrical measurement on single cells. Lab Chip 11(18):3174-3181.
    • (2011) Lab Chip , vol.11 , Issue.18 , pp. 3174-3181
    • Chen, J.1
  • 28
    • 84930900055 scopus 로고    scopus 로고
    • A physical sciences network characterization of circulating tumor cell aggregate transport
    • King MR, et al. (2015) A physical sciences network characterization of circulating tumor cell aggregate transport. Am J Physiol Cell Physiol 308(10):C792-C802.
    • (2015) Am J Physiol Cell Physiol , vol.308 , Issue.10 , pp. C792-C802
    • King, M.R.1
  • 29
    • 0023905877 scopus 로고
    • Dynamic measurement of human capillary blood pressure
    • Williams SA, et al. (1988) Dynamic measurement of human capillary blood pressure. Clin Sci (Lond) 74(5):507-512.
    • (1988) Clin Sci (Lond , vol.74 , Issue.5 , pp. 507-512
    • Williams, S.A.1
  • 30
    • 84934437818 scopus 로고    scopus 로고
    • A microfluidic device for label-free, physical capture of circulating tumor cell clusters
    • Sarioglu AF, et al. (2015) A microfluidic device for label-free, physical capture of circulating tumor cell clusters. Nat Methods 12(7):685-691.
    • (2015) Nat Methods , vol.12 , Issue.7 , pp. 685-691
    • Sarioglu, A.F.1
  • 31
    • 84898772852 scopus 로고    scopus 로고
    • Inertia-And deformation-driven migration of a soft particle in confined shear and poiseuille flow
    • Chen Y-L (2014) Inertia-And deformation-driven migration of a soft particle in confined shear and Poiseuille flow. RSC Advances 4(34):17908-17916.
    • (2014) RSC Advances , vol.4 , Issue.34 , pp. 17908-17916
    • Chen, Y.-L.1
  • 32
    • 84867335560 scopus 로고    scopus 로고
    • Adhesion functions in cell sorting by mechanically coupling the cortices of adhering cells
    • Maǐtre JL, et al. (2012) Adhesion functions in cell sorting by mechanically coupling the cortices of adhering cells. Science 338(6104):253-256.
    • (2012) Science , vol.338 , Issue.6104 , pp. 253-256
    • Maǐtre, J.L.1
  • 33
    • 0037440455 scopus 로고    scopus 로고
    • Cadherin-mediated cell adhesion and tissue segregation: Qualitative and quantitative determinants
    • Duguay D, Foty RA, Steinberg MS (2003) Cadherin-mediated cell adhesion and tissue segregation: Qualitative and quantitative determinants. Dev Biol 253(2):309-323.
    • (2003) Dev Biol , vol.253 , Issue.2 , pp. 309-323
    • Duguay, D.1    Foty, R.A.2    Steinberg, M.S.3
  • 34
    • 57349153946 scopus 로고    scopus 로고
    • A small molecule inhibitor,1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the y397 site of focal adhesion kinase decreases tumor growth
    • Golubovskaya VM, et al. (2008) A small molecule inhibitor, 1,2,4,5-benzenetetraamine tetrahydrochloride, targeting the Y397 site of focal adhesion kinase decreases tumor growth. J Med Chem 51(23):7405-7416.
    • (2008) J Med Chem , vol.51 , Issue.23 , pp. 7405-7416
    • Golubovskaya, V.M.1
  • 35
    • 0035119798 scopus 로고    scopus 로고
    • Disruption of cell adhesion and caspase-mediated proteolysis of beta-And gamma-catenins and apc protein in paclitaxel-induced apoptosis
    • Ling Y, Zhong Y, Perez-Soler R (2001) Disruption of cell adhesion and caspase-mediated proteolysis of beta-And gamma-catenins and APC protein in paclitaxel-induced apoptosis. Mol Pharmacol 59(3):593-603.
    • (2001) Mol Pharmacol , vol.59 , Issue.3 , pp. 593-603
    • Ling, Y.1    Zhong, Y.2    Perez-Soler, R.3
  • 36
    • 0035865186 scopus 로고    scopus 로고
    • The vascular anatomy of the developing zebrafish: An atlas of embryonic and early larval development
    • Isogai S, Horiguchi M, Weinstein BM (2001) The vascular anatomy of the developing zebrafish: An atlas of embryonic and early larval development. Dev Biol 230(2):278-301.
    • (2001) Dev Biol , vol.230 , Issue.2 , pp. 278-301
    • Isogai, S.1    Horiguchi, M.2    Weinstein, B.M.3
  • 37
    • 84900328794 scopus 로고    scopus 로고
    • Imaging circulating tumor cells in freely moving awake small animals using a miniaturized intravital microscope
    • Sasportas LS, Gambhir SS (2014) Imaging circulating tumor cells in freely moving awake small animals using a miniaturized intravital microscope. PLoS One 9(1):e86759.
    • (2014) PLoS One , vol.9 , Issue.1 , pp. e86759
    • Sasportas, L.S.1    Gambhir, S.S.2
  • 38
    • 0034307696 scopus 로고    scopus 로고
    • Structure and function of the developing zebrafish heart
    • Hu N, Sedmera D, Yost HJ, Clark EB (2000) Structure and function of the developing zebrafish heart. Anat Rec 260(2):148-157.
    • (2000) Anat Rec , vol.260 , Issue.2 , pp. 148-157
    • Hu, N.1    Sedmera, D.2    Yost, H.J.3    Clark, E.B.4
  • 39
    • 84892566999 scopus 로고    scopus 로고
    • Physical biology in cancer. 4. Physical cues guide tumor cell adhesion and migration
    • Stroka KM, Konstantopoulos K (2014) Physical biology in cancer. 4. Physical cues guide tumor cell adhesion and migration. Am J Physiol Cell Physiol 306(2):C98-C109.
    • (2014) Am J Physiol Cell Physiol , vol.306 , Issue.2 , pp. C98-C109
    • Stroka, K.M.1    Konstantopoulos, K.2
  • 41
    • 78649872067 scopus 로고    scopus 로고
    • Isolation of circulating tumor cells using a microvortex-generating herringbone-chip
    • Stott SL, et al. (2010) Isolation of circulating tumor cells using a microvortex-generating herringbone-chip. Proc Natl Acad Sci USA 107(43):18392-18397.
    • (2010) Proc Natl Acad Sci USA , vol.107 , Issue.43 , pp. 18392-18397
    • Stott, S.L.1
  • 42
    • 78751469492 scopus 로고    scopus 로고
    • A fast and simple method to fabricate circular microchannels in polydimethylsiloxane (pdms
    • Abdelgawad M, et al. (2011) A fast and simple method to fabricate circular microchannels in polydimethylsiloxane (PDMS). Lab Chip 11(3):545-551.
    • (2011) Lab Chip , vol.11 , Issue.3 , pp. 545-551
    • Abdelgawad, M.1
  • 43
    • 77249100175 scopus 로고    scopus 로고
    • A circular cross-section pdms microfluidics system for replication of cardiovascular flow conditions
    • Fiddes LK, et al. (2010) A circular cross-section PDMS microfluidics system for replication of cardiovascular flow conditions. Biomaterials 31(13):3459-3464.
    • (2010) Biomaterials , vol.31 , Issue.13 , pp. 3459-3464
    • Fiddes, L.K.1
  • 44
    • 77956583636 scopus 로고    scopus 로고
    • Moesin1 and ve-cadherin are required in endothelial cells during in vivo tubulogenesis
    • Wang Y, et al. (2010) Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis. Development 137(18):3119-3128.
    • (2010) Development , vol.137 , Issue.18 , pp. 3119-3128
    • Wang, Y.1
  • 45
    • 77956256911 scopus 로고    scopus 로고
    • Migration and fractionation of deformable particles in microchannel
    • Hsu CW, Chen YL (2010) Migration and fractionation of deformable particles in microchannel. J Chem Phys 133(3):034906.
    • (2010) J Chem Phys , vol.133 , Issue.3 , pp. 034906
    • Hsu, C.W.1    Chen, Y.L.2
  • 46
    • 0014668756 scopus 로고
    • Deformation of red blood cells in capillaries
    • Skalak R, Branemark PI (1969) Deformation of red blood cells in capillaries. Science 164(3880):717-719.
    • (1969) Science , vol.164 , Issue.3880 , pp. 717-719
    • Skalak, R.1    Branemark, P.I.2
  • 48
    • 0001096532 scopus 로고
    • Pressure-forcing of tightly fitting pellets along fluid-filled elastic tubes
    • Lighthill MJ (1968) Pressure-forcing of tightly fitting pellets along fluid-filled elastic tubes. J Fluid Mech 34(1):113-143.
    • (1968) J Fluid Mech , vol.34 , Issue.1 , pp. 113-143
    • Lighthill, M.J.1
  • 49
    • 84902531817 scopus 로고    scopus 로고
    • The effects of 3d channel geometry on ctc passing pressure-towards deformability-based cancer cell separation
    • Zhang Z, Xu J, Hong B, Chen X (2014) The effects of 3D channel geometry on CTC passing pressure-towards deformability-based cancer cell separation. Lab Chip 14(14):2576-2584.
    • (2014) Lab Chip , vol.14 , Issue.14 , pp. 2576-2584
    • Zhang, Z.1    Xu, J.2    Hong, B.3    Chen, X.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.