TDP-43 suppresses tau expression via promoting its mRNA instability

Nucleic Acids Research

Volumn 45, Issue 10, 2017, Pages 6177-6193

  Gu, Jianlan ^a,b,c   Wu, Feng ^a,b   Xu, Wen ^a,b   Shi, Jianhua ^a,b   Hu, Wen ^a,b   Jin, Nana ^a   Qian, Wei ^a,c   Wang, Xinglong ^d   Iqbal, Khalid ^b   Gong, Cheng Xin ^a,b   Liu, Fei ^a,b  

^a NANTONG UNIVERSITY   (China)

^b NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^c NANTONG MEDICAL COLLEGE   (China)

^d CASE WESTERN RESERVE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; TAR DNA BINDING PROTEIN; TAU PROTEIN; 3' UNTRANSLATED REGION; DNA BINDING PROTEIN; HYBRID PROTEIN; MAPT PROTEIN, HUMAN; TDP-43 PROTEIN, HUMAN;

3' UNTRANSLATED REGION; ADULT; AGED; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CEREBELLUM; CLINICAL ARTICLE; CONTROLLED STUDY; CYTOPLASM; DEGENERATIVE DISEASE; DOWN REGULATION; FEMALE; FRONTAL CORTEX; GENE MUTATION; GENOMIC INSTABILITY; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; IN VIVO STUDY; MALE; MOUSE; NEUROPATHOLOGY; NONHUMAN; NUCLEOTIDE REPEAT; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN ASSEMBLY; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN RNA BINDING; PROTEIN SYNTHESIS INHIBITION; RAT; TRANSGENIC MOUSE; VERY ELDERLY; ANIMAL; ANTAGONISTS AND INHIBITORS; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; CHEMISTRY; FRONTAL LOBE; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PHYSIOLOGY; PROTEIN DOMAIN; RNA INTERFERENCE; RNA STABILITY; WISTAR RAT;

3' UNTRANSLATED REGIONS; AGED; AGED, 80 AND OVER; ANIMALS; CELLS, CULTURED; CEREBELLUM; DNA-BINDING PROTEINS; FEMALE; FRONTAL LOBE; GENE EXPRESSION REGULATION; HUMANS; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; NEURODEGENERATIVE DISEASES; PROTEIN DOMAINS; RATS; RATS, WISTAR; RECOMBINANT FUSION PROTEINS; RNA INTERFERENCE; RNA STABILITY; RNA, MESSENGER; TAU PROTEINS;

EID: 85018520657     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkx175     Document Type: Article

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