-
1
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai T, Hasegawa M, Akiyama H, Ikeda K, Nonaka T, Mori H, Mann D, Tsuchiya K, Yoshida M, Hashizume Y, Oda T (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem Biophys Res Commun 351:602-611
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
Ikeda, K.4
Nonaka, T.5
Mori, H.6
Mann, D.7
Tsuchiya, K.8
Yoshida, M.9
Hashizume, Y.10
Oda, T.11
-
2
-
-
17144426507
-
Human, drosophila, and C. elegans TDP43: Nucleic acid binding properties and splicing regulatory function
-
Ayala YM, Pantano S, D'Ambrogio A, Buratti E, Brindisi A, Marchetti C, Romano M, Baralle FE (2005) Human, Drosophila, and C. elegans TDP43: nucleic acid binding properties and splicing regulatory function. J Mol Biol 348:575-588
-
(2005)
J. Mol. Biol.
, vol.348
, pp. 575-588
-
-
Ayala, Y.M.1
Pantano, S.2
D'Ambrogio, A.3
Buratti, E.4
Brindisi, A.5
Marchetti, C.6
Romano, M.7
Baralle, F.E.8
-
3
-
-
59549094064
-
Structural determinants of the cellular localization and shuttling of TDP-43
-
Ayala YM, Zago P, D'Ambrogio A, Xu YF, Petrucelli L, Buratti E, Baralle FE (2008) Structural determinants of the cellular localization and shuttling of TDP-43. J Cell Sci 121:3778-3785
-
(2008)
J. Cell. Sci.
, vol.121
, pp. 3778-3785
-
-
Ayala, Y.M.1
Zago, P.2
D'Ambrogio, A.3
Xu, Y.F.4
Petrucelli, L.5
Buratti, E.6
Baralle, F.E.7
-
4
-
-
38449102667
-
Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease
-
Buratti E, Baralle FE (2008) Multiple roles of TDP-43 in gene expression, splicing regulation, and human disease. Front Biosci 13:867-878
-
(2008)
Front Biosci
, vol.13
, pp. 867-878
-
-
Buratti, E.1
Baralle, F.E.2
-
5
-
-
27844514227
-
TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: An important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing
-
Buratti E, Brindisi A, Giombi M, Tisminetzky S, Ayala YM, Baralle FE (2005) TDP-43 binds heterogeneous nuclear ribonucleoprotein A/B through its C-terminal tail: an important region for the inhibition of cystic fibrosis transmembrane conductance regulator exon 9 splicing. J Biol Chem 280:37572-37584
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 37572-37584
-
-
Buratti, E.1
Brindisi, A.2
Giombi, M.3
Tisminetzky, S.4
Ayala, Y.M.5
Baralle, F.E.6
-
6
-
-
33646826619
-
Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases
-
Choi J, Sullards MC, Olzmann JA, Rees HD, Weintraub ST, Bostwick DE, Gearing M, Levey AI, Chin LS, Li L (2006) Oxidative damage of DJ-1 is linked to sporadic Parkinson and Alzheimer diseases. J Biol Chem 281:10816-10824
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 10816-10824
-
-
Choi, J.1
Sullards, M.C.2
Olzmann, J.A.3
Rees, H.D.4
Weintraub, S.T.5
Bostwick, D.E.6
Gearing, M.7
Levey, A.I.8
Chin, L.S.9
Li, L.10
-
7
-
-
33750568162
-
Dimerization of ubiquilin is dependent upon the central region of the protein: Evidence that the monomer, but not the dimer, is involved in binding presenilins
-
Ford DL, Monteiro MJ (2006) Dimerization of ubiquilin is dependent upon the central region of the protein: evidence that the monomer, but not the dimer, is involved in binding presenilins. Biochem J 399:397-404
-
(2006)
Biochem. J.
, vol.399
, pp. 397-404
-
-
Ford, D.L.1
Monteiro, M.J.2
-
8
-
-
68349125007
-
Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: The TDP-43 diseases
-
Geser F, Martinez-Lage M, Kwong LK, Lee VM, Trojanowski JQ (2009) Amyotrophic lateral sclerosis, frontotemporal dementia and beyond: the TDP-43 diseases. J Neurol 256:1205-1214
-
(2009)
J. Neurol.
, vol.256
, pp. 1205-1214
-
-
Geser, F.1
Martinez-Lage, M.2
Kwong, L.K.3
Lee, V.M.4
Trojanowski, J.Q.5
-
9
-
-
47949086625
-
Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Hasegawa M, Arai T, Nonaka T, Kametani F, Yoshida M, Hashizume Y, Beach TG, Buratti E, Baralle F, Morita M, Nakano I, Oda T, Tsuchiya K, Akiyama H (2008) Phosphorylated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Ann Neurol 64:60-70
-
(2008)
Ann. Neurol.
, vol.64
, pp. 60-70
-
-
Hasegawa, M.1
Arai, T.2
Nonaka, T.3
Kametani, F.4
Yoshida, M.5
Hashizume, Y.6
Beach, T.G.7
Buratti, E.8
Baralle, F.9
Morita, M.10
Nakano, I.11
Oda, T.12
Tsuchiya, K.13
Akiyama, H.14
-
10
-
-
44049097065
-
A yeast TDP-43 proteinopathy model: Exploring the molecular determinants of TDP-43 aggregation and cellular toxicity
-
Johnson BS, McCaffery JM, Lindquist S, Gitler AD (2008) A yeast TDP-43 proteinopathy model: exploring the molecular determinants of TDP-43 aggregation and cellular toxicity. Proc Natl Acad Sci USA 105:6439-6444
-
(2008)
Proc. Natl. Acad. Sci. USA
, vol.105
, pp. 6439-6444
-
-
Johnson, B.S.1
McCaffery, J.M.2
Lindquist, S.3
Gitler, A.D.4
-
11
-
-
67749133873
-
TDP-43 is intrinsically aggregation-prone and ALS-linked mutations accelerate aggregation and increase toxicity
-
Johnson BS, Snead D, Lee JJ, McCaffery JM, Shorter J, Gitler AD (2009) TDP-43 is intrinsically aggregation-prone and ALS-linked mutations accelerate aggregation and increase toxicity. J Biol Chem 284:20329-20339
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 20329-20339
-
-
Johnson, B.S.1
Snead, D.2
Lee, J.J.3
McCaffery, J.M.4
Shorter, J.5
Gitler, A.D.6
-
12
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
Kabashi E, Valdmanis PN, Dion P, Spiegelman D, McConkey BJ, Vande Velde C, Bouchard JP, Lacomblez L, Pochigaeva K, Salachas F, Pradat PF, Camu W, Meininger V, Dupre N, Rouleau GA (2008) TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat Genet 40:572-574
-
(2008)
Nat. Genet.
, vol.40
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
Spiegelman, D.4
McConkey, B.J.5
Velde, C.V.6
Bouchard, J.P.7
Lacomblez, L.8
Pochigaeva, K.9
Salachas, F.10
Pradat, P.F.11
Camu, W.12
Meininger, V.13
Dupre, N.14
Rouleau, G.A.15
-
13
-
-
63349083295
-
Identification of casein kinase-1 phosphorylation sites on TDP-43
-
Kametani F, Nonaka T, Suzuki T, Arai T, Dohmae N, Akiyama H, Hasegawa M (2009) Identification of casein kinase-1 phosphorylation sites on TDP-43. Biochem Biophys Res Commun 382:405-409
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.382
, pp. 405-409
-
-
Kametani, F.1
Nonaka, T.2
Suzuki, T.3
Arai, T.4
Dohmae, N.5
Akiyama, H.6
Hasegawa, M.7
-
14
-
-
65549084887
-
Potentiation of ALS-associated TDP-43 aggregation by the proteasome-targeting factor, uilin 1
-
Kim SH, Shi Y, Hanson KA, Williams LM, Sakasai R, Bowler MJ, Tibbetts RS (2008) Potentiation of ALS-associated TDP-43 aggregation by the proteasome-targeting factor, uilin 1. J Biol Chem 284:8083-8092
-
(2008)
J. Biol. Chem.
, vol.284
, pp. 8083-8092
-
-
Kim, S.H.1
Shi, Y.2
Hanson, K.A.3
Williams, L.M.4
Sakasai, R.5
Bowler, M.J.6
Tibbetts, R.S.7
-
15
-
-
64549100193
-
Structural insights into TDP-43 in nucleic-acid binding and domain interactions
-
Kuo PH, Doudeva LG, Wang YT, Shen CK, Yuan HS (2009) Structural insights into TDP-43 in nucleic-acid binding and domain interactions. Nucleic Acids Res 37:1799-1808
-
(2009)
Nucleic Acids Res.
, vol.37
, pp. 1799-1808
-
-
Kuo, P.H.1
Doudeva, L.G.2
Wang, Y.T.3
Shen, C.K.4
Yuan, H.S.5
-
16
-
-
58049221032
-
Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: Implications for TDP-43 in the physiological response to neuronal injury
-
Moisse K, Volkening K, Leystra-Lantz C, Welch I, Hill T, Strong MJ (2009) Divergent patterns of cytosolic TDP-43 and neuronal progranulin expression following axotomy: implications for TDP-43 in the physiological response to neuronal injury. Brain Res 1249:202-211
-
(2009)
Brain Res.
, vol.1249
, pp. 202-211
-
-
Moisse, K.1
Volkening, K.2
Leystra-Lantz, C.3
Welch, I.4
Hill, T.5
Strong, M.J.6
-
17
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M, Sampathu DM, Kwong LK, Truax AC, Micsenyi MC, Chou TT, Bruce J, Schuck T, Grossman M, Clark CM, McCluskey LF, Miller BL, Masliah E, Mackenzie IR, Feldman H, Feiden W, Kretzschmar HA, Trojanowski JQ, Lee VM (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314:130-133
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
Truax, A.C.4
Micsenyi, M.C.5
Chou, T.T.6
Bruce, J.7
Schuck, T.8
Grossman, M.9
Clark, C.M.10
McCluskey, L.F.11
Miller, B.L.12
Masliah, E.13
Mackenzie, I.R.14
Feldman, H.15
Feiden, W.16
Kretzschmar, H.A.17
Trojanowski, J.Q.18
Lee, V.M.19
-
18
-
-
59249085091
-
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies
-
Neumann M, Kwong LK, Lee EB, Kremmer E, Flatley A, Xu Y, Forman MS, Troost D, Kretzschmar HA, Trojanowski JQ, Lee VM (2009) Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies. Acta Neuropathol 117:137-149
-
(2009)
Acta Neuropathol
, vol.117
, pp. 137-149
-
-
Neumann, M.1
Kwong, L.K.2
Lee, E.B.3
Kremmer, E.4
Flatley, A.5
Xu, Y.6
Forman, M.S.7
Troost, D.8
Kretzschmar, H.A.9
Trojanowski, J.Q.10
Lee, V.M.11
-
19
-
-
67650113333
-
Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43
-
Nonaka T, Kametani F, Arai T, Akiyama H, Hasegawa M (2009a) Truncation and pathogenic mutations facilitate the formation of intracellular aggregates of TDP-43. Hum Mol Genet 18:3353-3364
-
(2009)
Hum Mol. Genet.
, vol.18
, pp. 3353-3364
-
-
Nonaka, T.1
Kametani, F.2
Arai, T.3
Akiyama, H.4
Hasegawa, M.5
-
20
-
-
58149498300
-
Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells
-
Nonaka T, Arai T, Buratti E, Baralle FE, Akiyama H, Hasegawa M (2009b) Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells. FEBS Lett 583:394-400
-
(2009)
FEBS Lett.
, vol.583
, pp. 394-400
-
-
Nonaka, T.1
Arai, T.2
Buratti, E.3
Baralle, F.E.4
Akiyama, H.5
Hasegawa, M.6
-
21
-
-
0029066110
-
Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs
-
Ou SH, Wu F, Harrich D, García-Martínez LF, Gaynor RB (1995) Cloning and characterization of a novel cellular protein, TDP-43, that binds to human immunodeficiency virus type 1 TAR DNA sequence motifs. J Virol 69:3584-3596
-
(1995)
J. Virol.
, vol.69
, pp. 3584-3596
-
-
Ou, S.H.1
Wu, F.2
Harrich, D.3
García-Martínez, L.F.4
Gaynor, R.B.5
-
22
-
-
58849108962
-
Protein microarray analysis identifies human cellular prion protein interactors
-
Satoh J, Obayashi S, Misawa T, Sumiyoshi K, Oosumi K, Tabunoki H (2009) Protein microarray analysis identifies human cellular prion protein interactors. Neuropathol Appl Neurobiol 35:16-35
-
(2009)
Neuropathol Appl. Neurobiol.
, vol.35
, pp. 16-35
-
-
Satoh, J.1
Obayashi, S.2
Misawa, T.3
Sumiyoshi, K.4
Oosumi, K.5
Tabunoki, H.6
-
23
-
-
63949083624
-
Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression
-
Tatom JB, Wang DB, Dayton RD, Skalli O, Hutton ML, Dickson DW, Klein RL (2009) Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression. Mol Ther 17:607-613
-
(2009)
Mol. Ther.
, vol.17
, pp. 607-613
-
-
Tatom, J.B.1
Wang, D.B.2
Dayton, R.D.3
Skalli, O.4
Hutton, M.L.5
Dickson, D.W.6
Klein, R.L.7
-
24
-
-
54249100481
-
TDP-43: An emerging new player in neurodegenerative diseases
-
Wang IF, Wu LS, Shen CK (2008) TDP-43: an emerging new player in neurodegenerative diseases. Trends Mol Med 14:479-485
-
(2008)
Trends Mol. Med.
, vol.14
, pp. 479-485
-
-
Wang, I.F.1
Wu, L.S.2
Shen, C.K.3
-
25
-
-
44749091997
-
Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation
-
Winton MJ, Igaz LM, Wong MM, Kwong LK, Trojanowski JQ, Lee VM (2008) Disturbance of nuclear and cytoplasmic TAR DNA-binding protein (TDP-43) induces disease-like redistribution, sequestration, and aggregate formation. J Biol Chem 283:13302-13309
-
(2008)
J. Biol. Chem.
, vol.283
, pp. 13302-13309
-
-
Winton, M.J.1
Igaz, L.M.2
Wong, M.M.3
Kwong, L.K.4
Trojanowski, J.Q.5
Lee, V.M.6
-
26
-
-
34848921202
-
Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43
-
Zhang YJ, Xu YF, Dickey CA, Buratti E, Baralle F, Bailey R, Pickering-Brown S, Dickson D, Petrucelli L (2007) Progranulin mediates caspase-dependent cleavage of TAR DNA binding protein-43. J Neurosci 27:10530-10534
-
(2007)
J. Neurosci.
, vol.27
, pp. 10530-10534
-
-
Zhang, Y.J.1
Xu, Y.F.2
Dickey, C.A.3
Buratti, E.4
Baralle, F.5
Bailey, R.6
Pickering-Brown, S.7
Dickson, D.8
Petrucelli, L.9
-
27
-
-
66149114101
-
Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity
-
Zhang YJ, Xu YF, Cook C, Gendron TF, Roettges P, Link CD, Lin WL, Tong J, Castanedes-Casey M, Ash P, Gass J, Rangachari V, Buratti E, Baralle F, Golde TE, Dickson DW, Petrucelli L (2009) Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity. Proc Natl Acad Sci USA 106:7607-7612
-
(2009)
Proc. Natl. Acad. Sci. USA
, vol.106
, pp. 7607-7612
-
-
Zhang, Y.J.1
Xu, Y.F.2
Cook, C.3
Gendron, T.F.4
Roettges, P.5
Link, C.D.6
Lin, W.L.7
Tong, J.8
Castanedes-Casey, M.9
Ash, P.10
Gass, J.11
Rangachari, V.12
Buratti, E.13
Baralle, F.14
Golde, T.E.15
Dickson, D.W.16
Petrucelli, L.17
|