Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data

PLoS Medicine

Volumn 14, Issue 4, 2017, Pages

  White, Charles C ^a,b   Yang, Hyun Sik ^a,b,c,d   Yu, Lei ^e,f   Chibnik, Lori B ^b,g   Dawe, Robert J ^e,f   Yang, Jingyun ^e,f   Klein, Hans Ulrich ^a,b,d   Felsky, Daniel ^a,b,d   Ramos Miguel, Alfredo ^h   Arfanakis, Konstantinos ^e,f,i   Honer, William G ^h   Sperling, Reisa A ^c,d   Schneider, Julie A ^e,f   Bennett, David A ^e,f   De Jager, Philip L ^a,b,j  

^a Brigham and Womens Hospital   (United States)

^b BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

^d HARVARD MEDICAL SCHOOL   (United States)

^e RUSH UNIVERSITY MEDICAL CENTER   (United States)

^f RUSH UNIVERSITY MEDICAL CENTER   (United States)

^g HARVARD SCHOOL OF PUBLIC HEALTH   (United States)

^h UNIVERSITY OF BRITISH COLUMBIA   (Canada)

ⁱ Illinois Institute of Technology   (United States)

^j Department of Medicine   (United States)

more..

Author keywords

[No Author keywords available]

Indexed keywords

AGING; ARTERIOLOSCLEROSIS; ARTICLE; ATHEROSCLEROSIS; BRAIN REGION; COGNITION; COGNITIVE DEFECT; DEMENTIA; DISEASE SEVERITY; DNA METHYLATION; EPIGENETICS; GENETIC ANALYSIS; GENETIC ASSOCIATION; GENOME-WIDE ASSOCIATION STUDY; HEART INFARCTION; HIPPOCAMPAL SCLEROSIS; LEWY BODY; NEUROFIBRILLARY TANGLE; NEUROPATHOLOGY; NEUROPSYCHIATRY; PHENOTYPE; RNA SEQUENCE; TDP 43 PROTEINOPATHY; TRANSCRIPTOMICS; VASCULAR AMYLOIDOSIS; AGED; ALLELE; ALZHEIMER DISEASE; BRAIN; DEPRESSION; FEMALE; GENE LINKAGE DISEQUILIBRIUM; GENETIC EPIGENESIS; GENETICS; GENOTYPE; HUMAN; MALE; MEMORY; METABOLISM; PATHOLOGY; PATHOPHYSIOLOGY; PHYSIOLOGY; SINGLE NUCLEOTIDE POLYMORPHISM; VERY ELDERLY;

ACTIN BINDING PROTEIN; CELL SURFACE RECEPTOR; ECTODERMAL-NEURAL CORTEX 1 PROTEIN; MEMBRANE PROTEIN; NERVE PROTEIN; NEUROPEPTIDE; NUCLEAR PROTEIN; RNA; TMEM106B PROTEIN, HUMAN; UNC5C PROTEIN, HUMAN;

AGED; AGED, 80 AND OVER; AGING; ALLELES; ALZHEIMER DISEASE; BRAIN; COGNITION; COGNITION DISORDERS; DEPRESSION; DNA METHYLATION; EPIGENESIS, GENETIC; FEMALE; GENOME-WIDE ASSOCIATION STUDY; GENOTYPE; HUMANS; LINKAGE DISEQUILIBRIUM; MALE; MEMBRANE PROTEINS; MEMORY; MICROFILAMENT PROTEINS; NERVE TISSUE PROTEINS; NEUROPEPTIDES; NUCLEAR PROTEINS; POLYMORPHISM, SINGLE NUCLEOTIDE; RECEPTORS, CELL SURFACE; RNA; TDP-43 PROTEINOPATHIES;

EID: 85018366108     PISSN: 15491277     EISSN: 15491676     Source Type: Journal    
DOI: 10.1371/journal.pmed.1002287     Document Type: Article

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