-
1
-
-
34447316702
-
Genetics of Alzheimer's disease: A centennial review
-
Ertekin-Taner N. Genetics of Alzheimer's disease: a centennial review. Neurol Clin. 2007;25(3):611-667; v.
-
(2007)
Neurol Clin
, vol.25
, Issue.3
-
-
Ertekin-Taner, N.1
-
2
-
-
84864471159
-
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline
-
Jónsson T, Atwal JK, Steinberg S, et al. A mutation in APP protects against Alzheimer's disease and age-related cognitive decline. Nature. 2012;488(7409):96-99.
-
(2012)
Nature
, vol.488
, Issue.7409
, pp. 96-99
-
-
Jónsson, T.1
Atwal, J.K.2
Steinberg, S.3
-
3
-
-
84860764162
-
Role of common and rare APP DNA sequence variants in Alzheimer disease
-
Hooli BV, Mohapatra G, Mattheisen M, et al. Role of common and rare APP DNA sequence variants in Alzheimer disease. Neurology. 2012;78(16):1250-1257.
-
(2012)
Neurology
, vol.78
, Issue.16
, pp. 1250-1257
-
-
Hooli, B.V.1
Mohapatra, G.2
Mattheisen, M.3
-
4
-
-
34250819923
-
Association studies testing for risk for late-onset Alzheimer's disease with common variants in the beta-amyloid precursor protein (APP)
-
DOI 10.1002/ajmg.b.30485
-
Nowotny P, Simcock X, Bertelsen S, et al. Association studies testing for risk for late-onset Alzheimer's disease with common variants in the beta-amyloid precursor protein (APP). Am J Med Genet B Neuropsychiatr Genet. 2007;144B(4):469-474. (Pubitemid 46983157)
-
(2007)
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
, vol.144
, Issue.4
, pp. 469-474
-
-
Nowotny, P.1
Simcock, X.2
Bertelsen, S.3
Hinrichs, A.L.4
Kauwe, J.S.K.5
Mayo, K.6
Smemo, S.7
Morris, J.C.8
Goate, A.9
-
5
-
-
33947492770
-
Variations in the APP gene promoter region and risk of Alzheimer disease
-
DOI 10.1212/01.wnl.0000255938.33739.46, PII 0000611420070227000014
-
Guyant-Maréchal L, Rovelet-Lecrux A, Goumidi L, et al. Variations in the APP gene promoter region and risk of Alzheimer disease. Neurology. 2007;68(9):684-687. (Pubitemid 46667816)
-
(2007)
Neurology
, vol.68
, Issue.9
, pp. 684-687
-
-
Guyant-Marechal, L.1
Rovelet-Lecrux, A.2
Goumidi, L.3
Cousin, E.4
Hannequin, D.5
Raux, G.6
Penet, C.7
Ricard, S.8
Mace, S.9
Amouyel, P.10
Deleuze, J.-F.11
Frebourg, T.12
Brice, A.13
Lambert, J.-C.14
Campion, D.15
-
6
-
-
0036845563
-
Polymorphisms in the promoter of the human APP gene: Functional evaluation and allele frequencies in Alzheimer disease
-
DOI 10.1001/archneur.59.11.1793
-
Athan ES, Lee JH, Arriaga A, Mayeux RP, Tycko B. Polymorphisms in the promoter of the human APP gene: functional evaluation and allele frequencies in Alzheimer disease. Arch Neurol. 2002;59(11):1793-1799. (Pubitemid 35340491)
-
(2002)
Archives of Neurology
, vol.59
, Issue.11
, pp. 1793-1799
-
-
Athan, E.S.1
Lee, J.H.2
Arriaga, A.3
Mayeux, R.P.4
Tycko, B.5
-
7
-
-
79959772357
-
Human apoE isoforms differentially regulate brain amyloid-β peptide clearance
-
Castellano JM, Kim J, Stewart FR, et al. Human apoE isoforms differentially regulate brain amyloid-β peptide clearance. Sci Transl Med. 2011;3(89):89ra57.
-
(2011)
Sci Transl Med
, vol.3
, Issue.89
-
-
Castellano, J.M.1
Kim, J.2
Stewart, F.R.3
-
8
-
-
70349558522
-
Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease
-
Harold D, Abraham R, Hollingworth P, et al. Genome-wide association study identifies variants at CLU and PICALM associated with Alzheimer's disease. Nat Genet. 2009;41(10):1088-1093.
-
(2009)
Nat Genet
, vol.41
, Issue.10
, pp. 1088-1093
-
-
Harold, D.1
Abraham, R.2
Hollingworth, P.3
-
9
-
-
79955484414
-
Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease
-
Alzheimer's Disease Neuroimaging Initiative; CHARGE Consortium; EADI1 Consortium
-
Hollingworth P, Harold D, Sims R, et al Alzheimer's Disease Neuroimaging Initiative; CHARGE Consortium; EADI1 Consortium. Common variants at ABCA7, MS4A6A/MS4A4E, EPHA1, CD33 and CD2AP are associated with Alzheimer's disease. Nat Genet. 2011;43(5):429-435.
-
(2011)
Nat Genet
, vol.43
, Issue.5
, pp. 429-435
-
-
Hollingworth, P.1
Harold, D.2
Sims, R.3
-
10
-
-
79955464911
-
Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease
-
Naj AC, Jun G, Beecham GW, et al. Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease. Nat Genet. 2011;43(5):436-441.
-
(2011)
Nat Genet
, vol.43
, Issue.5
, pp. 436-441
-
-
Naj, A.C.1
Jun, G.2
Beecham, G.W.3
-
11
-
-
78549264026
-
Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease
-
European Alzheimer's Disease Initiative Investigators
-
Lambert JC, Heath S, Even G, et al European Alzheimer's Disease Initiative Investigators. Genome-wide association study identifies variants at CLU and CR1 associated with Alzheimer's disease. Nat Genet. 2009;41(10):1094- 1099.
-
(2009)
Nat Genet
, vol.41
, Issue.10
, pp. 1094-1099
-
-
Lambert, J.C.1
Heath, S.2
Even, G.3
-
12
-
-
77952307991
-
Genome-wide analysis of genetic loci associated with Alzheimer disease
-
CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium
-
Seshadri S, Fitzpatrick AL, Ikram MA, et al CHARGE Consortium; GERAD1 Consortium; EADI1 Consortium. Genome-wide analysis of genetic loci associated with Alzheimer disease. JAMA. 2010;303(18):1832-1840.
-
(2010)
JAMA
, vol.303
, Issue.18
, pp. 1832-1840
-
-
Seshadri, S.1
Fitzpatrick, A.L.2
Ikram, M.A.3
-
13
-
-
9144224765
-
ApoE and Clusterin Cooperatively Suppress Abeta Levels and Deposition: Evidence that ApoE Regulates Extracellular Abeta Metabolism In Vivo
-
DOI 10.1016/S0896-6273(03)00850-X
-
DeMattos RB, Cirrito JR, Parsadanian M, et al. ApoE and clusterin cooperatively suppress Abeta levels and deposition: evidence that ApoE regulates extracellular Abeta metabolism in vivo. Neuron. 2004;41(2):193-202. (Pubitemid 38125181)
-
(2004)
Neuron
, vol.41
, Issue.2
, pp. 193-202
-
-
DeMattos, R.B.1
Cirrito, J.R.2
Parsadanian, M.3
May, P.C.4
O'Dell, M.A.5
Taylor, J.W.6
Harmony, J.A.K.7
Aronow, B.J.8
Bales, K.R.9
Paul, S.M.10
Holtzman, D.M.11
-
14
-
-
79953277743
-
CR1 is associated with amyloid plaque burden and age-related cognitive decline
-
Chibnik LB, Shulman JM, Leurgans SE, et al. CR1 is associated with amyloid plaque burden and age-related cognitive decline. Ann Neurol. 2011;69(3):560-569.
-
(2011)
Ann Neurol
, vol.69
, Issue.3
, pp. 560-569
-
-
Chibnik, L.B.1
Shulman, J.M.2
Leurgans, S.E.3
-
15
-
-
23944526029
-
Amyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people
-
DOI 10.1136/jnnp.2004.054445
-
Bennett DA, Schneider JA, Wilson RS, Bienias JL, Berry-Kravis E, Arnold SE. Amyloid mediates the association of apolipoprotein E e4 allele to cognitive function in older people. J Neurol Neurosurg Psychiatry. 2005;76(9):1194-1199. (Pubitemid 41208366)
-
(2005)
Journal of Neurology, Neurosurgery and Psychiatry
, vol.76
, Issue.9
, pp. 1194-1199
-
-
Bennett, D.A.1
Schneider, J.A.2
Wilson, R.S.3
Bienias, J.L.4
Berry-Kravis, E.5
Arnold, S.E.6
-
16
-
-
0036679142
-
Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice
-
Wyss-Coray T, Yan F, Lin AH-T, et al. Prominent neurodegeneration and increased plaque formation in complement-inhibited Alzheimer's mice. Proc Natl Acad Sci U S A. 2002;99(16):10837-10842.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, Issue.16
, pp. 10837-10842
-
-
Wyss-Coray, T.1
Yan, F.2
Lin, A.H.-T.3
-
17
-
-
82755197062
-
Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast
-
Treusch S, Hamamichi S, Goodman JL, et al. Functional links between Aβ toxicity, endocytic trafficking, and Alzheimer's disease risk factors in yeast. Science. 2011;334(6060):1241-1245.
-
(2011)
Science
, vol.334
, Issue.6060
, pp. 1241-1245
-
-
Treusch, S.1
Hamamichi, S.2
Goodman, J.L.3
-
18
-
-
36148972426
-
Pathological correlates of dementia in a longitudinal, population-based sample of aging
-
DOI 10.1002/ana.21208
-
Sonnen JA, Larson EB, Crane PK, et al. Pathological correlates of dementia in a longitudinal, population-based sample of aging. Ann Neurol. 2007;62(4):406-413. (Pubitemid 350105954)
-
(2007)
Annals of Neurology
, vol.62
, Issue.4
, pp. 406-413
-
-
Sonnen, J.A.1
Larson, E.B.2
Crane, P.K.3
Haneuse, S.4
Li, G.5
Schellenberg, G.D.6
Craft, S.7
Leverenz, J.B.8
Montine, T.J.9
-
19
-
-
70149097327
-
The neuropathology of probable Alzheimer disease and mild cognitive impairment
-
Schneider JA, Arvanitakis Z, Leurgans SE, Bennett DA. The neuropathology of probable Alzheimer disease and mild cognitive impairment. Ann Neurol. 2009;66(2):200-208.
-
(2009)
Ann Neurol
, vol.66
, Issue.2
, pp. 200-208
-
-
Schneider, J.A.1
Arvanitakis, Z.2
Leurgans, S.E.3
Bennett, D.A.4
-
20
-
-
55949117032
-
Frequent amyloid deposition without significant cognitive impairment among the elderly
-
Aizenstein HJ, Nebes RD, Saxton JA, et al. Frequent amyloid deposition without significant cognitive impairment among the elderly. Arch Neurol. 2008;65(11):1509-1517.
-
(2008)
Arch Neurol
, vol.65
, Issue.11
, pp. 1509-1517
-
-
Aizenstein, H.J.1
Nebes, R.D.2
Saxton, J.A.3
-
21
-
-
39749108812
-
11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment
-
DOI 10.1093/brain/awm336
-
Jack CR Jr, Lowe VJ, Senjem ML, et al. 11C PiB and structural MRI provide complementary information in imaging of Alzheimer's disease and amnestic mild cognitive impairment. Brain. 2008;131(pt 3):665-680. (Pubitemid 351294719)
-
(2008)
Brain
, vol.131
, Issue.3
, pp. 665-680
-
-
Jack Jr., C.R.1
Lowe, V.J.2
Senjem, M.L.3
Weigand, S.D.4
Kemp, B.J.5
Shiung, M.M.6
Knopman, D.S.7
Boeve, B.F.8
Klunk, W.E.9
Mathis, C.A.10
Petersen, R.C.11
-
22
-
-
66149084048
-
Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease
-
Reiman EM, Chen K, Liu X, et al. Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease. Proc Natl Acad Sci U S A. 2009;106(16):6820-6825.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, Issue.16
, pp. 6820-6825
-
-
Reiman, E.M.1
Chen, K.2
Liu, X.3
-
23
-
-
79956098248
-
Toward defining the preclinical stages of Alzheimer's disease: Recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease
-
Sperling RA, Aisen PS, Beckett LA, et al. Toward defining the preclinical stages of Alzheimer's disease: recommendations from the National Institute on Aging-Alzheimer's Association workgroups on diagnostic guidelines for Alzheimer's disease. Alzheimers Dement. 2011;7(3):280-292.
-
(2011)
Alzheimers Dement
, vol.7
, Issue.3
, pp. 280-292
-
-
Sperling, R.A.1
Aisen, P.S.2
Beckett, L.A.3
-
24
-
-
77649314191
-
APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging
-
Morris JC, Roe CM, Xiong C, et al. APOE predicts amyloid-beta but not tau Alzheimer pathology in cognitively normal aging. Ann Neurol. 2010;67(1):122-131.
-
(2010)
Ann Neurol
, vol.67
, Issue.1
, pp. 122-131
-
-
Morris, J.C.1
Roe, C.M.2
Xiong, C.3
-
25
-
-
67549134932
-
Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles
-
Bennett DA, De Jager PL, Leurgans SE, Schneider JA. Neuropathologic intermediate phenotypes enhance association to Alzheimer susceptibility alleles. Neurology. 2009;72(17):1495-1503.
-
(2009)
Neurology
, vol.72
, Issue.17
, pp. 1495-1503
-
-
Bennett, D.A.1
De Jager, P.L.2
Leurgans, S.E.3
Schneider, J.A.4
-
26
-
-
36749067250
-
Exploring candidate gene associations with neuropsychological performance
-
DOI 10.1002/ajmg.b.30500
-
McQueen MB, Bertram L, Lange C, et al. Exploring candidate gene associations with neuropsychological performance. Am J Med Genet B Neuropsychiatr Genet. 2007;144B(8):987-991. (Pubitemid 350207770)
-
(2007)
American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics
, vol.144
, Issue.8
, pp. 987-991
-
-
McQueen, M.B.1
Bertram, L.2
Lange, C.3
Becker, K.D.4
Albert, M.S.5
Tanzi, R.E.6
Blacker, D.7
-
27
-
-
84863546263
-
Overview and findings from the Religious Orders Study
-
Bennett DA, Schneider JA, Arvanitakis Z, Wilson RS. Overview and findings from the Religious Orders Study. Curr Alzheimer Res. 2012;9(6):628-645.
-
(2012)
Curr Alzheimer Res
, vol.9
, Issue.6
, pp. 628-645
-
-
Bennett, D.A.1
Schneider, J.A.2
Arvanitakis, Z.3
Wilson, R.S.4
-
28
-
-
84863542698
-
Overview and findings from the Rush Memory and Aging Project
-
Bennett DAD, Schneider JAJ, Buchman ASA, Barnes LLL, Boyle PAP, Wilson RSR. Overview and findings from the Rush Memory and Aging Project. Curr Alzheimer Res. 2012;9(6):646-663.
-
(2012)
Curr Alzheimer Res
, vol.9
, Issue.6
, pp. 646-663
-
-
Bennett, D.A.D.1
Schneider, J.A.J.2
Buchman, A.S.A.3
Barnes, L.L.L.4
Boyle, P.A.P.5
Wilson, R.S.R.6
-
29
-
-
84860488892
-
A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline
-
Alzheimer's Disease Neuroimaging Initiative
-
Keenan BT, Shulman JM, Chibnik LB, et al Alzheimer's Disease Neuroimaging Initiative. A coding variant in CR1 interacts with APOE-ε4 to influence cognitive decline. Hum Mol Genet. 2012;21(10):2377-2388.
-
(2012)
Hum Mol Genet
, vol.21
, Issue.10
, pp. 2377-2388
-
-
Keenan, B.T.1
Shulman, J.M.2
Chibnik, L.B.3
-
30
-
-
0021271971
-
Clinical diagnosis of Alzheimer's disease: Report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services Task Force on Alzheimer's disease
-
McKhann G, Drachman D, Folstein M, Katzman R, Price D, Stadlan EM. Clinical diagnosis of Alzheimer's disease: report of the NINCDS-ADRDA Work Group under the auspices of Department of Health and Human Services Task Force on Alzheimer's Disease. Neurology. 1984;34(7):939-944. (Pubitemid 14076461)
-
(1984)
Neurology
, vol.34
, Issue.7
, pp. 939-944
-
-
McKhann, G.1
Drachman, D.2
Folstein, M.3
-
31
-
-
0030681215
-
Consensus recommendations for the postmortem diagnosis of Alzheimer's disease
-
National Institute on Aging; Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease
-
National Institute on Aging; Reagan Institute Working Group on Diagnostic Criteria for the Neuropathological Assessment of Alzheimer's Disease. Consensus recommendations for the postmortem diagnosis of Alzheimer's disease. Neurobiol Aging. 1997;18(4)(suppl):S1-S2.
-
(1997)
Neurobiol Aging
, vol.18
, Issue.4 SUPPL.
-
-
-
32
-
-
79959453425
-
RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration
-
Massone S, Vassallo I, Castelnuovo M, et al. RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration. J Cell Biol. 2011;193(5):851-866.
-
(2011)
J Cell Biol
, vol.193
, Issue.5
, pp. 851-866
-
-
Massone, S.1
Vassallo, I.2
Castelnuovo, M.3
-
33
-
-
34347239326
-
A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population
-
DOI 10.1086/518720
-
Liu F, Arias-Vásquez A, Sleegers K, et al. A genomewide screen for late-onset Alzheimer disease in a genetically isolated Dutch population. Am J Hum Genet. 2007;81(1):17-31. (Pubitemid 47001153)
-
(2007)
American Journal of Human Genetics
, vol.81
, Issue.1
, pp. 17-31
-
-
Liu, F.1
Arias-Vasquez, A.2
Sleegers, K.3
Aulchenko, Y.S.4
Kayser, M.5
Sanchez-Juan, P.6
Feng, B.-J.7
Bertoli-Avella, A.M.8
Van Swieten, J.9
Axenovich, T.I.10
Heutink, P.11
Van Broeckhoven, C.12
Oostra, B.A.13
Van Duijn, C.M.14
-
34
-
-
29444442794
-
APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy
-
DOI 10.1038/ng1718
-
Rovelet-Lecrux A, Hannequin D, Raux G, et al. APP locus duplication causes autosomal dominant early-onset Alzheimer disease with cerebral amyloid angiopathy. Nat Genet. 2006;38(1):24-26. (Pubitemid 43011878)
-
(2006)
Nature Genetics
, vol.38
, Issue.1
, pp. 24-26
-
-
Rovelet-Lecrux, A.1
Hannequin, D.2
Raux, G.3
Le, M.N.4
Laquerriere, A.5
Vital, A.6
Dumanchin, C.7
Feuillette, S.8
Brice, A.9
Vercelletto, M.10
Dubas, F.11
Frebourg, T.12
Campion, D.13
-
35
-
-
0037177892
-
Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4
-
DOI 10.1074/jbc.M200897200
-
Morohashi Y, Hatano N, Ohya S, et al. Molecular cloning and characterization of CALP/KChIP4, a novel EF-hand protein interacting with presenilin 2 and voltage-gated potassium channel subunit Kv4. J Biol Chem. 2002;277(17):14965-14975. (Pubitemid 34952571)
-
(2002)
Journal of Biological Chemistry
, vol.277
, Issue.17
, pp. 14965-14975
-
-
Morohashi, Y.1
Hatano, N.2
Ohya, S.3
Takikawa, R.4
Watabiki, T.5
Takasugi, N.6
Imaizumi, Y.7
Tomita, T.8
Iwatsubo, T.9
-
36
-
-
47249162481
-
Cyclooxygenase-1 and -2 in the different stages of Alzheimer's disease pathology
-
DOI 10.2174/138161208784480171
-
Hoozemans JJM, Rozemuller JM, van Haastert ES, Veerhuis R, Eikelenboom P. Cyclooxygenase-1 and -2 in the different stages of Alzheimer's disease pathology. Curr Pharm Des. 2008;14(14):1419-1427. (Pubitemid 351982549)
-
(2008)
Current Pharmaceutical Design
, vol.14
, Issue.14
, pp. 1419-1427
-
-
Hoozemans, J.J.M.1
Rozemuller, J.M.2
Van Haastert, E.S.3
Veerhuis, R.4
Eikelenboom, P.5
-
37
-
-
42249103603
-
NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration
-
DOI 10.1038/nature06721, PII NATURE06721
-
Zhai RG, Zhang F, Hiesinger PR, Cao Y, Haueter CM, Bellen HJ. NAD synthase NMNAT acts as a chaperone to protect against neurodegeneration. Nature. 2008;452(7189):887-891. (Pubitemid 351550857)
-
(2008)
Nature
, vol.452
, Issue.7189
, pp. 887-891
-
-
Zhai, R.G.1
Zhang, F.2
Hiesinger, P.R.3
Cao, Y.4
Haueter, C.M.5
Bellen, H.J.6
-
38
-
-
84868099498
-
Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease
-
Arnold SE, Louneva N, Cao K, et al. Cellular, synaptic, and biochemical features of resilient cognition in Alzheimer's disease. Neurobiol Aging. 2013;34(1):157-168.
-
(2013)
Neurobiol Aging
, vol.34
, Issue.1
, pp. 157-168
-
-
Arnold, S.E.1
Louneva, N.2
Cao, K.3
|