-
1
-
-
77952293063
-
Functions and regulation of RNA editing by ADAR deaminases
-
Nishikura, K. (2010) Functions and Regulation of RNA Editing by ADAR Deaminases. Annu. Rev. Biochem., 79, 321-349.
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 321-349
-
-
Nishikura, K.1
-
2
-
-
33847317017
-
Redirection of silencing targets by adenosine-to-inosine editing of miRNAs
-
Kawahara, Y., Zinshteyn, B., Sethupathy, P., Iizasa, H., Hatzigeorgiou, A.G. and Nishikura, K. (2007) Redirection of silencing targets by adenosine-to-inosine editing of miRNAs. Science, 315, 1137-1140.
-
(2007)
Science
, vol.315
, pp. 1137-1140
-
-
Kawahara, Y.1
Zinshteyn, B.2
Sethupathy, P.3
Iizasa, H.4
Hatzigeorgiou, A.G.5
Nishikura, K.6
-
3
-
-
30044443191
-
Modulation of microRNA processing and expression through RNA editing by ADAR deaminases
-
Yang, W., Chendrimada, T.P., Wang, Q., Higuchi, M., Seeburg, P.H., Shiekhattar, R. and Nishikura, K. (2006) Modulation of microRNA processing and expression through RNA editing by ADAR deaminases. Nat. Struct. Mol. Biol., 13, 13-21.
-
(2006)
Nat. Struct. Mol. Biol.
, vol.13
, pp. 13-21
-
-
Yang, W.1
Chendrimada, T.P.2
Wang, Q.3
Higuchi, M.4
Seeburg, P.H.5
Shiekhattar, R.6
Nishikura, K.7
-
4
-
-
0033529064
-
Regulation of alternative splicing by RNA editing
-
Rueter, S.M., Dawson, T.R. and Emeson, R.B. (1999) Regulation of alternative splicing by RNA editing. Nature, 399, 75-80.
-
(1999)
Nature
, vol.399
, pp. 75-80
-
-
Rueter, S.M.1
Dawson, T.R.2
Emeson, R.B.3
-
5
-
-
0028961902
-
Glutamate receptor RNA editing in vitro by enzymatic conversion of adenosine to inosine
-
Rueter, S.M., Burns, C.M., Coode, S.A., Mookherjee, P. and Emeson, R.B. (1995) Glutamate receptor RNA editing in vitro by enzymatic conversion of adenosine to inosine. Science, 267, 1491-1494.
-
(1995)
Science
, vol.267
, pp. 1491-1494
-
-
Rueter, S.M.1
Burns, C.M.2
Coode, S.A.3
Mookherjee, P.4
Emeson, R.B.5
-
6
-
-
0030051809
-
A mammalian RNA editing enzyme
-
Melcher, T., Maas, S., Herb, A., Sprengel, R., Seeburg, P.H. and Higuchi, M. (1996) A mammalian RNA editing enzyme, Nature, 379, 460-464.
-
(1996)
Nature
, vol.379
, pp. 460-464
-
-
Melcher, T.1
Maas, S.2
Herb, A.3
Sprengel, R.4
Seeburg, P.H.5
Higuchi, M.6
-
7
-
-
0035997389
-
RNA editing by Adenosine Deaminases that act on RNA
-
Bass, B.L. (2002) RNA editing by Adenosine Deaminases that act on RNA. Annu. Rev. Biochem., 71, 817-846.
-
(2002)
Annu. Rev. Biochem.
, vol.71
, pp. 817-846
-
-
Bass, B.L.1
-
8
-
-
77953708337
-
Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome
-
Morabito, M.V., Abbas, A.I., Hood, J.L., Kesterson, R.A., Jacobs, M.M., Kump, D.S., Hachey, D.L., Roth, B.L. and Emeson, R.B. (2010) Mice with altered serotonin 2C receptor RNA editing display characteristics of Prader-Willi syndrome. Neurobiol. Dis., 39, 169-180.
-
(2010)
Neurobiol. Dis.
, vol.39
, pp. 169-180
-
-
Morabito, M.V.1
Abbas, A.I.2
Hood, J.L.3
Kesterson, R.A.4
Jacobs, M.M.5
Kump, D.S.6
Hachey, D.L.7
Roth, B.L.8
Emeson, R.B.9
-
9
-
-
33646759917
-
A-to-I RNA editing and human disease
-
Maas, S., Kawahara, Y., Tamburro, K.M. and Nishikura, K. (2006) A-to-I RNA editing and human disease. RNA Biol., 3, 1-9.
-
(2006)
RNA Biol.
, vol.3
, pp. 1-9
-
-
Maas, S.1
Kawahara, Y.2
Tamburro, K.M.3
Nishikura, K.4
-
10
-
-
84888866436
-
Adenosine-to-inosine RNA editing and human disease
-
Slotkin, W. and Nishikura, K. (2013) Adenosine-to-inosine RNA editing and human disease. Genome Med., 5, 105-118.
-
(2013)
Genome Med.
, vol.5
, pp. 105-118
-
-
Slotkin, W.1
Nishikura, K.2
-
11
-
-
84855403375
-
Deregulation of the A-to-I RNA editing mechanism in psychiatric disorders
-
Silberberg, G., Lundin, D., Navon, R. and O?hman, M. (2012) Deregulation of the A-to-I RNA editing mechanism in psychiatric disorders. Hum. Mol. Genet., 21, 311-321.
-
(2012)
Hum. Mol. Genet.
, vol.21
, pp. 311-321
-
-
Silberberg, G.1
Lundin, D.2
Navon, R.3
Ohman, M.4
-
12
-
-
0034612640
-
Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2
-
Higuchi, M., Maas, S., Single, F.N., Hartner, J., Rozov, A., Burnashev, N., Feldmeyer, D., Sprengel, R. and Seeburg, P.H. (2000) Point mutation in an AMPA receptor gene rescues lethality in mice deficient in the RNA-editing enzyme ADAR2. Nature, 406, 78-81.
-
(2000)
Nature
, vol.406
, pp. 78-81
-
-
Higuchi, M.1
Maas, S.2
Single, F.N.3
Hartner, J.4
Rozov, A.5
Burnashev, N.6
Feldmeyer, D.7
Sprengel, R.8
Seeburg, P.H.9
-
13
-
-
84868207785
-
Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature
-
Rice, G.I., Kasher, P.R., Forte, G.M., Mannion, N.M., Greenwood, S.M., Szynkiewicz, M., Dickerson, J.E., Bhaskar, S.S., Zampini, M., Briggs, T.A. et al. (2012) Mutations in ADAR1 cause Aicardi-Goutières syndrome associated with a type I interferon signature. Nat. Genet., 44, 1243-1248.
-
(2012)
Nat. Genet.
, vol.44
, pp. 1243-1248
-
-
Rice, G.I.1
Kasher, P.R.2
Forte, G.M.3
Mannion, N.M.4
Greenwood, S.M.5
Szynkiewicz, M.6
Dickerson, J.E.7
Bhaskar, S.S.8
Zampini, M.9
Briggs, T.A.10
-
14
-
-
4544284817
-
Seven novel mutations of the ADAR gene in Chinese families and sporadic patients with dyschromatosis symmetrica hereditaria (DSH)
-
Zhang, X.J., He, P.P., Li, M., He, C.D., Yan, K.L., Cui, Y., Yang, S., Zhang, K.Y., Gao, M., Chen, J.J. et al. (2004) Seven novel mutations of the ADAR gene in Chinese families and sporadic patients with dyschromatosis symmetrica hereditaria (DSH). Hum. Mutat., 23, 629-630.
-
(2004)
Hum. Mutat.
, vol.23
, pp. 629-630
-
-
Zhang, X.J.1
He, P.P.2
Li, M.3
He, C.D.4
Yan, K.L.5
Cui, Y.6
Yang, S.7
Zhang, K.Y.8
Gao, M.9
Chen, J.J.10
-
15
-
-
1042278125
-
Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1
-
Hartner, J.C., Schmittwolf, C., Kispert, A., Muller, A.M., Higuchi, M. and Seeburg, P.H. (2004) Liver disintegration in the mouse embryo caused by deficiency in the RNA-editing enzyme ADAR1. J. Biol. Chem., 279, 4894-4902.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4894-4902
-
-
Hartner, J.C.1
Schmittwolf, C.2
Kispert, A.3
Muller, A.M.4
Higuchi, M.5
Seeburg, P.H.6
-
16
-
-
1042289736
-
Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene
-
Wang, Q., Miyakoda, M., Yang, W., Khillan, J., Stachura, D.L., Weiss, M.J. and Nishikura, K. (2004) Stress-induced apoptosis associated with null mutation of ADAR1 RNA editing deaminase gene. J. Biol. Chem., 279, 4952-4961.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 4952-4961
-
-
Wang, Q.1
Miyakoda, M.2
Yang, W.3
Khillan, J.4
Stachura, D.L.5
Weiss, M.J.6
Nishikura, K.7
-
17
-
-
84941100160
-
RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself
-
Liddicoat, B.J., Piskol, R., Chalk, A.M., Ramaswami, G., Higuchi, M., Hartner, J.C., Li, J.B., Seeburg, P.H. and Walkley, C.R. (2015) RNA editing by ADAR1 prevents MDA5 sensing of endogenous dsRNA as nonself. Science, 349, 1115-1120.
-
(2015)
Science
, vol.349
, pp. 1115-1120
-
-
Liddicoat, B.J.1
Piskol, R.2
Chalk, A.M.3
Ramaswami, G.4
Higuchi, M.5
Hartner, J.C.6
Li, J.B.7
Seeburg, P.H.8
Walkley, C.R.9
-
18
-
-
84912098781
-
The RNA-editing enzyme ADAR1 controls innate immune responses to RNA
-
Mannion, N.M., Greenwood, S.M., Young, R., Cox, S., Brindle, J., Read, D., Nellaker, C., Vesely, C., Ponting, C.P., McLaughlin, P.J. et al. (2014) The RNA-editing enzyme ADAR1 controls innate immune responses to RNA. Cell Rep., 9, 1482-1494.
-
(2014)
Cell Rep.
, vol.9
, pp. 1482-1494
-
-
Mannion, N.M.1
Greenwood, S.M.2
Young, R.3
Cox, S.4
Brindle, J.5
Read, D.6
Nellaker, C.7
Vesely, C.8
Ponting, C.P.9
McLaughlin, P.J.10
-
19
-
-
84873531277
-
Recoding RNA editing of antizyme inhibitor 1 predisposes to hepatocellular carcinoma
-
Chen, L., Li, Y., Lin, C.H., Chan, T.H., Chow, R.K., Song, Y., Liu, M., Yuan, Y.F., Fu, L., Kong, K.L. et al. (2013) Recoding RNA editing of antizyme inhibitor 1 predisposes to hepatocellular carcinoma. Nat. Med., 19, 209-216.
-
(2013)
Nat. Med.
, vol.19
, pp. 209-216
-
-
Chen, L.1
Li, Y.2
Lin, C.H.3
Chan, T.H.4
Chow, R.K.5
Song, Y.6
Liu, M.7
Yuan, Y.F.8
Fu, L.9
Kong, K.L.10
-
20
-
-
84874622310
-
RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling
-
Shimokawa, T., Rahman, M.F., Tostar, U., Sonkoly, E., Ståhle, M., Pivarcsi, A., Palaniswamy, R. and Zaphiropoulos, P.G. (2013) RNA editing of the GLI1 transcription factor modulates the output of Hedgehog signaling. RNA Biol., 10, 321-333.
-
(2013)
RNA Biol.
, vol.10
, pp. 321-333
-
-
Shimokawa, T.1
Rahman, M.F.2
Tostar, U.3
Sonkoly, E.4
Ståhle, M.5
Pivarcsi, A.6
Palaniswamy, R.7
Zaphiropoulos, P.G.8
-
21
-
-
84873540802
-
RNA editing enters the limelight in cancer
-
Gallo, A. (2013) RNA editing enters the limelight in cancer. Nat. Med., 19, 130-131.
-
(2013)
Nat. Med.
, vol.19
, pp. 130-131
-
-
Gallo, A.1
-
22
-
-
84944040819
-
Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors
-
Paz-Yaacov, N., Bazak, L., Buchumenski, I., Porath, H.T., Danan-Gotthold, M., Knisbacher, B.A., Eisenberg, E. and Levanon, E.Y. (2015) Elevated RNA Editing Activity Is a Major Contributor to Transcriptomic Diversity in Tumors. Cell Reports, 13, 267-276.
-
(2015)
Cell Reports
, vol.13
, pp. 267-276
-
-
Paz-Yaacov, N.1
Bazak, L.2
Buchumenski, I.3
Porath, H.T.4
Danan-Gotthold, M.5
Knisbacher, B.A.6
Eisenberg, E.7
Levanon, E.Y.8
-
23
-
-
84944062619
-
The genomic landscape and clinical relevance of A-to-I RNA editing in human cancers
-
Han, L., Diao, L., Yu, S., Xu, X., Li, J., Zhang, R., Yang, Y., Werner, H.M., Eterovic, A.K., Yuan, Y., Li, J. et al. (2015) The genomic landscape and clinical relevance of A-to-I RNA editing in human cancers. Cancer Cell, 28, 515-528.
-
(2015)
Cancer Cell
, vol.28
, pp. 515-528
-
-
Han, L.1
Diao, L.2
Yu, S.3
Xu, X.4
Li, J.5
Zhang, R.6
Yang, Y.7
Werner, H.M.8
Eterovic, A.K.9
Yuan, Y.10
Li, J.11
-
24
-
-
84943621334
-
Profiling RNA editing in human tissues: Towards the inosinome Atlas
-
Picardi, E., Manzari, C., Mastropasqua, F., Aiello, I., D'Erchia, A.M. and Pesole, G. (2015) Profiling RNA editing in human tissues: Towards the inosinome Atlas. Sci. Rep., 5, 14941-14956.
-
(2015)
Sci. Rep.
, vol.5
, pp. 14941-14956
-
-
Picardi, E.1
Manzari, C.2
Mastropasqua, F.3
Aiello, I.4
D'Erchia, A.M.5
Pesole, G.6
-
25
-
-
84863229628
-
Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome
-
Peng, Z., Cheng, Y., Tan, B.C., Kang, L., Tian, Z., Zhu, Y., Zhang, W., Liang, Y., Hu, X., Tan, X. et al. (2012) Comprehensive analysis of RNA-Seq data reveals extensive RNA editing in a human transcriptome. Nat. Biotech., 30, 253-260.
-
(2012)
Nat. Biotech.
, vol.30
, pp. 253-260
-
-
Peng, Z.1
Cheng, Y.2
Tan, B.C.3
Kang, L.4
Tian, Z.5
Zhu, Y.6
Zhang, W.7
Liang, Y.8
Hu, X.9
Tan, X.10
-
26
-
-
84895535383
-
A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes
-
Bazak, L., Haviv, A., Barak, M., Jacob-Hirsch, J., Deng, P., Zhang, R., Isaacs, F.J., Rechavi, G., Li, J.B., Eisenberg, E. et al. (2014) A-to-I RNA editing occurs at over a hundred million genomic sites, located in a majority of human genes. Genome Res., 24, 365-376.
-
(2014)
Genome Res.
, vol.24
, pp. 365-376
-
-
Bazak, L.1
Haviv, A.2
Barak, M.3
Jacob-Hirsch, J.4
Deng, P.5
Zhang, R.6
Isaacs, F.J.7
Rechavi, G.8
Li, J.B.9
Eisenberg, E.10
-
27
-
-
84861970552
-
Accurate identification of human Alu and non-Alu RNA editing sites
-
Ramaswami, G., Lin, W., Piskol, R., Tan, M.H., Davis, C. and Li, J.B. (2012) Accurate identification of human Alu and non-Alu RNA editing sites. Nat. Meth., 9, 579-581.
-
(2012)
Nat. Meth.
, vol.9
, pp. 579-581
-
-
Ramaswami, G.1
Lin, W.2
Piskol, R.3
Tan, M.H.4
Davis, C.5
Li, J.B.6
-
28
-
-
77957822421
-
The solution structure of the ADAR2 dsRBM-RNA complex reveals a sequence-specific readout of the minor groove
-
Stefl, R., Oberstrass, F.C., Hood, J.L., Jourdan, M., Zimmermann, M., Skrisovska, L., Maris, C., Peng, L., Hofr, C., Emeson, R.B. et al. (2010) The solution structure of the ADAR2 dsRBM-RNA complex reveals a sequence-specific readout of the minor groove. Cell, 143, 225-237.
-
(2010)
Cell
, vol.143
, pp. 225-237
-
-
Stefl, R.1
Oberstrass, F.C.2
Hood, J.L.3
Jourdan, M.4
Zimmermann, M.5
Skrisovska, L.6
Maris, C.7
Peng, L.8
Hofr, C.9
Emeson, R.B.10
-
29
-
-
85027937587
-
Site-directed RNA editing with Antagomir Deaminases - A tool to study protein and RNA function
-
Vogel, P. and Stafforst, T. (2014) Site-directed RNA editing with Antagomir Deaminases - A tool to study protein and RNA function. ChemMedChem, 9, 2021-2025.
-
(2014)
ChemMedChem
, vol.9
, pp. 2021-2025
-
-
Vogel, P.1
Stafforst, T.2
-
30
-
-
84923106217
-
Therapeutic genome editing: Prospects and challenges
-
Cox, D.B., Platt, R.J. and Zhang, F. (2015) Therapeutic genome editing: Prospects and challenges. Nat. Med., 21, 121-131.
-
(2015)
Nat. Med.
, vol.21
, pp. 121-131
-
-
Cox, D.B.1
Platt, R.J.2
Zhang, F.3
-
31
-
-
84937764228
-
An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia
-
Sehgal, A., Barros, S., Ivanciu, L., Cooley, B., Qin, J., Racie, T., Hettinger, J., Carioto, M., Jiang, Y., Brodsky, J. et al. (2015) An RNAi therapeutic targeting antithrombin to rebalance the coagulation system and promote hemostasis in hemophilia. Nat. Med., 21, 491-497.
-
(2015)
Nat. Med.
, vol.21
, pp. 491-497
-
-
Sehgal, A.1
Barros, S.2
Ivanciu, L.3
Cooley, B.4
Qin, J.5
Racie, T.6
Hettinger, J.7
Carioto, M.8
Jiang, Y.9
Brodsky, J.10
-
32
-
-
85018359650
-
Use of liposomes in the treatment of cystic fibrosis
-
In: Albeda, SM (ed). CRC Press, NY
-
Stern, M. and Alton, E.W.F.W. (2002) Use of liposomes in the treatment of cystic fibrosis. In: Albeda, SM (ed). Gene Therapy in Lung Disease: Lung Biology in Health and Disease. CRC Press, NY, Vol. 169, pp. 383-396.
-
(2002)
Gene Therapy in Lung Disease: Lung Biology in Health and Disease.
, vol.169
, pp. 383-396
-
-
Stern, M.1
Alton, E.W.F.W.2
-
33
-
-
0029090176
-
Towards the therapeutic editing of mutated RNA sequences
-
Woolf, T.M., Chase, J.M. and Stinchcomb, D.T. (1995) Towards the therapeutic editing of mutated RNA sequences. Proc. Natl. Acad. Sci. U.S.A., 92, 8298-8302.
-
(1995)
Proc. Natl. Acad. Sci. U.S.A.
, vol.92
, pp. 8298-8302
-
-
Woolf, T.M.1
Chase, J.M.2
Stinchcomb, D.T.3
-
34
-
-
84867835332
-
An RNA-Deaminase conjugate selectively repairs point mutations
-
Stafforst, T. and Schneider, M.F. (2012) An RNA-Deaminase conjugate selectively repairs point mutations. Angew. Chem. Int. Ed. Engl., 51, 11166-11169.
-
(2012)
Angew. Chem. Int. Ed. Engl.
, vol.51
, pp. 11166-11169
-
-
Stafforst, T.1
Schneider, M.F.2
-
35
-
-
84902201236
-
Improving site-directed RNA editing in vitro and in cell culture by chemical modification of the guideRNA
-
Vogel, P., Schneider, M.F., Wettengel, J. and Stafforst, T. (2014) Improving site-directed RNA editing in vitro and in cell culture by chemical modification of the guideRNA. Angew. Chem. Int. Ed. Engl., 53, 6267-6271.
-
(2014)
Angew. Chem. Int. Ed. Engl.
, vol.53
, pp. 6267-6271
-
-
Vogel, P.1
Schneider, M.F.2
Wettengel, J.3
Stafforst, T.4
-
36
-
-
84887300101
-
Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing
-
Montiel-Gonzalez, M. F., Guillermo, I., Yudowski, A. and Rosenthal, J. J. C. (2013) Correction of mutations within the cystic fibrosis transmembrane conductance regulator by site-directed RNA editing. Proc. Natl. Acad. Sci. U.S.A., 110, 18285-18290.
-
(2013)
Proc. Natl. Acad. Sci. U.S.A.
, vol.110
, pp. 18285-18290
-
-
Montiel-Gonzalez, M.F.1
Guillermo, I.2
Yudowski, A.3
Rosenthal, J.J.C.4
-
37
-
-
84952837160
-
Site-directed RNA editing in vivo can be triggered by the light-driven assembly of an artificial riboprotein
-
Hanswillemenke, A., Kuzdere, T., Vogel, P., Jkely, G. and Stafforst, T. (2015) Site-directed RNA editing in vivo can be triggered by the light-driven assembly of an artificial riboprotein. J. Am. Chem. Soc., 137, 15875-15881.
-
(2015)
J. Am. Chem. Soc.
, vol.137
, pp. 15875-15881
-
-
Hanswillemenke, A.1
Kuzdere, T.2
Vogel, P.3
Jkely, G.4
Stafforst, T.5
-
38
-
-
37349093652
-
-
World Health Organization (WHO)., Geneva, ISBN 9241563362
-
World Health Organization (WHO). (2006) Neurological disorders: Public health challenges, Geneva, ISBN 9241563362.
-
(2006)
Neurological Disorders: Public Health Challenges
-
-
-
39
-
-
33645116252
-
Genetics of Parkinson disease: Paradigm shifts and future prospects
-
Farrer, M.J. (2006) Genetics of Parkinson disease: Paradigm shifts and future prospects. Nat. Rev. Gen., 7, 306-318.
-
(2006)
Nat. Rev. Gen.
, vol.7
, pp. 306-318
-
-
Farrer, M.J.1
-
40
-
-
2442668926
-
Hereditary early-onset Parkinson's disease caused by mutations in PINK1
-
Valente, E.M., Abou-Sleiman, P.M., Caputo, V., Muqit, M.M., Harvey, K., Gispert, S., Ali, Z., Del Turco, D., Bentivoglio, A.R., Healy, D.G. et al. (2004) Hereditary early-onset Parkinson's disease caused by mutations in PINK1. Science, 304, 1158-1160.
-
(2004)
Science
, vol.304
, pp. 1158-1160
-
-
Valente, E.M.1
Abou-Sleiman, P.M.2
Caputo, V.3
Muqit, M.M.4
Harvey, K.5
Gispert, S.6
Ali, Z.7
Del Turco, D.8
Bentivoglio, A.R.9
Healy, D.G.10
-
41
-
-
75949130828
-
PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1
-
Geisler, S., Holmstrm, K.M., Skujat, D., Fiesel, F.C., Rothfuss, O.C., Kahle, P.J. and Springer, W. (2010) PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1. Nat. Cell Biol., 12, 119-131.
-
(2010)
Nat. Cell Biol.
, vol.12
, pp. 119-131
-
-
Geisler, S.1
Holmstrm, K.M.2
Skujat, D.3
Fiesel, F.C.4
Rothfuss, O.C.5
Kahle, P.J.6
Springer, W.7
-
42
-
-
84903209128
-
Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans
-
Schneider, M.F., Wettengel, J., Hoffmann, P.C. and Stafforst, T. (2014) Optimal guideRNAs for re-directing deaminase activity of hADAR1 and hADAR2 in trans. Nucleic Acids Res., 42, e87.
-
(2014)
Nucleic Acids Res.
, vol.42
, pp. e87
-
-
Schneider, M.F.1
Wettengel, J.2
Hoffmann, P.C.3
Stafforst, T.4
-
43
-
-
84963603761
-
Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity
-
Matthews, M.M., Thomas, J.M., Zheng, Y., Tran, K., Phelps, K.J., Scott, A.I., Havel, J., Fisher, A.J. and Beal, P.A. (2016) Structures of human ADAR2 bound to dsRNA reveal base-flipping mechanism and basis for site selectivity. Nat. Struct. Mol. Biol., 23, 426-433.
-
(2016)
Nat. Struct. Mol. Biol.
, vol.23
, pp. 426-433
-
-
Matthews, M.M.1
Thomas, J.M.2
Zheng, Y.3
Tran, K.4
Phelps, K.J.5
Scott, A.I.6
Havel, J.7
Fisher, A.J.8
Beal, P.A.9
-
44
-
-
0037021345
-
Selection of hammerhead ribozyme variants with low Mg2+ requirement: Importance of stem-loop II
-
Persson, T., Hartmann, R. K. and Eckstein, F. (2002) Selection of hammerhead ribozyme variants with low Mg2+ requirement: Importance of stem-loop II. ChemBioChem, 3, 1066-1071.
-
(2002)
ChemBioChem
, vol.3
, pp. 1066-1071
-
-
Persson, T.1
Hartmann, R.K.2
Eckstein, F.3
-
45
-
-
0036245628
-
U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells
-
Miyagishi, M. and Taira, K. (2002) U6 promoter-driven siRNAs with four uridine 3' overhangs efficiently suppress targeted gene expression in mammalian cells. Nat. Biotech., 20, 497-500.
-
(2002)
Nat. Biotech.
, vol.20
, pp. 497-500
-
-
Miyagishi, M.1
Taira, K.2
-
46
-
-
0036256430
-
Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells
-
Lee, N. S., Dohjima, T., Bauer, G., Li, H., Li, M.J., Ehsani, A., Salvaterra, P. and Rossi, J.(2002) Expression of small interfering RNAs targeted against HIV-1 rev transcripts in human cells. Nat. Biotech., 20, 500-505.
-
(2002)
Nat. Biotech.
, vol.20
, pp. 500-505
-
-
Lee, N.S.1
Dohjima, T.2
Bauer, G.3
Li, H.4
Li, M.J.5
Ehsani, A.6
Salvaterra, P.7
Rossi, J.8
-
47
-
-
0036251639
-
Effective expression of small interfering RNA in human cells
-
Paul, C. P., Good, P. D., Winer, I. and Engelke, D. R. (2002) Effective expression of small interfering RNA in human cells. Nat. Biotech., 20, 505-508.
-
(2002)
Nat. Biotech.
, vol.20
, pp. 505-508
-
-
Paul, C.P.1
Good, P.D.2
Winer, I.3
Engelke, D.R.4
-
48
-
-
34547637607
-
LambdaN-GFP: An RNA reporter system for live-cell imaging
-
Daigle, N. and Ellenberg, J. (2007) LambdaN-GFP: An RNA reporter system for live-cell imaging. Nat. Methods, 4, 633-636.
-
(2007)
Nat. Methods
, vol.4
, pp. 633-636
-
-
Daigle, N.1
Ellenberg, J.2
-
49
-
-
38949107432
-
Tethering of proteins to RNAs by bacteriophage proteins
-
Keryer-Bibens, C., Barreau, C. and Osborne, H. B. (2008) Tethering of proteins to RNAs by bacteriophage proteins. Biol. Cell, 100, 125-138.
-
(2008)
Biol. Cell
, vol.100
, pp. 125-138
-
-
Keryer-Bibens, C.1
Barreau, C.2
Osborne, H.B.3
-
50
-
-
84865070369
-
A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity
-
Jinek, M., Chylinski, K., Fonfara, I., Hauer, M., Doudna, J.A. and Charpentier, E. (2012) A programmable dual-RNA-guided DNA endonuclease in adaptive bacterial immunity. Science, 337, 816-821.
-
(2012)
Science
, vol.337
, pp. 816-821
-
-
Jinek, M.1
Chylinski, K.2
Fonfara, I.3
Hauer, M.4
Doudna, J.A.5
Charpentier, E.6
-
51
-
-
75949098487
-
PINK1-dependent recruitment of Parkin to mitochondria in mitophagy
-
Vives-Bauza, C., Zhou, C., Huang, Y., Cui, M., de Vries, R.L., Kim, J., May, J., Tocilescu, M.A., Liu, W., Ko, H.S. et al. (2010) PINK1-dependent recruitment of Parkin to mitochondria in mitophagy. Proc. Natl. Acad. Sci. U.S.A., 107, 378-383.
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 378-383
-
-
Vives-Bauza, C.1
Zhou, C.2
Huang, Y.3
Cui, M.4
De Vries, R.L.5
Kim, J.6
May, J.7
Tocilescu, M.A.8
Liu, W.9
Ko, H.S.10
-
52
-
-
79956271523
-
Predicting sites of ADAR editing in double-stranded RNA
-
Eggington, J.M., Greene, T. and Bass, B.L. (2011) Predicting sites of ADAR editing in double-stranded RNA. Nat. Commun., 2, doi: 10.1038/ncomms1324.
-
(2011)
Nat. Commun.
, vol.2
-
-
Eggington, J.M.1
Greene, T.2
Bass, B.L.3
-
53
-
-
77949512140
-
RNA targeting therapeutics: Molecular mechanisms of antisense oligonucleotides as a therapeutic platform
-
Bennett, C.F. and Swayze, E.E. (2010) RNA targeting therapeutics: Molecular mechanisms of antisense oligonucleotides as a therapeutic platform. Annu. Rev. Pharmacol. Toxicol., 50, 259-293.
-
(2010)
Annu. Rev. Pharmacol. Toxicol.
, vol.50
, pp. 259-293
-
-
Bennett, C.F.1
Swayze, E.E.2
-
54
-
-
84856431819
-
RNA therapeutics: Beyond RNA interference and antisense oligonucleotides
-
Kole, R., Krainer, A.R. and Altman, S. (2012) RNA therapeutics: Beyond RNA interference and antisense oligonucleotides. Nat. Rev. Drug. Discov., 11, 125-140.
-
(2012)
Nat. Rev. Drug. Discov.
, vol.11
, pp. 125-140
-
-
Kole, R.1
Krainer, A.R.2
Altman, S.3
-
55
-
-
84982283717
-
The notorious R.N.A. in the spotlight - drug or target for the treatment of disease
-
Reautschnig, P., Vogel, P. and Stafforst, T. (2016) The notorious R.N.A. in the spotlight - drug or target for the treatment of disease. RNA Biol., doi: 10.1080/15476286.2016.1208323.
-
(2016)
RNA Biol.
-
-
Reautschnig, P.1
Vogel, P.2
Stafforst, T.3
-
56
-
-
84883118140
-
Safety and efficacy of RNAi therapy for transthyretin amyloidosis
-
Coelho, T., Adams, D., Silva, A., Lozeron, P., Hawkins, P.N., Mant, T., Perez, J., Chiesa, J., Warrington, S., Tranter, E. et al. (2013) Safety and efficacy of RNAi therapy for transthyretin amyloidosis. N. Engl. J. Med., 369, 819-829.
-
(2013)
N. Engl. J. Med.
, vol.369
, pp. 819-829
-
-
Coelho, T.1
Adams, D.2
Silva, A.3
Lozeron, P.4
Hawkins, P.N.5
Mant, T.6
Perez, J.7
Chiesa, J.8
Warrington, S.9
Tranter, E.10
-
57
-
-
84892741671
-
Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: A randomised, single-blind, placebo-controlled, phase 1 trial
-
Fitzgerald, K., Frank-Kamenetsky, M., Shulga-Morskaya, S., Liebow, A., Bettencourt, B.R., Sutherland, J.E., Hutabarat, R.M., Clausen, V.A., Karsten, V., Cehelsky, J. et al. (2014) Effect of an RNA interference drug on the synthesis of proprotein convertase subtilisin/kexin type 9 (PCSK9) and the concentration of serum LDL cholesterol in healthy volunteers: A randomised, single-blind, placebo-controlled, phase 1 trial. Lancet., 383, 60-68.
-
(2014)
Lancet.
, vol.383
, pp. 60-68
-
-
Fitzgerald, K.1
Frank-Kamenetsky, M.2
Shulga-Morskaya, S.3
Liebow, A.4
Bettencourt, B.R.5
Sutherland, J.E.6
Hutabarat, R.M.7
Clausen, V.A.8
Karsten, V.9
Cehelsky, J.10
|