GP73 represses host innate immune response to promote virus replication by facilitating MAVS and TRAF6 degradation

PLoS Pathogens

Volumn 13, Issue 4, 2017, Pages

  Zhang, Xuewu ^a   Zhu, Chengliang ^a   Wang, Tianci ^a   Jiang, Hui ^a   Ren, Yahui ^a   Zhang, Qi ^a   Wu, Kailang ^a   Liu, Fang ^a   Liu, Yingle ^a   Wu, Jianguo ^a  

^a WUHAN UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; BIOLOGICAL MARKER; GOLGI PROTEIN 73; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERFERON REGULATORY FACTOR 3; INTERLEUKIN 29; INTERLEUKIN 6; LENTIVIRUS VECTOR; MITOCHONDRIAL ANTIVIRAL SIGNALING PROTEIN; MITOCHONDRIAL PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE; N ACETYL BETA GLUCOSAMINIDASE; TUMOR NECROSIS FACTOR RECEPTOR ASSOCIATED FACTOR 6; UNCLASSIFIED DRUG; VIRUS RNA; ANTIVIRUS AGENT; GOLM1 PROTEIN, HUMAN; INTERFERON; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; VISA PROTEIN, HUMAN;

ADULT; ARTICLE; CELL FRACTIONATION; CONTROLLED STUDY; DOWN REGULATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GENE SILENCING; GENETIC TRANSFECTION; HEPATITIS C VIRUS; HUMAN; HUMAN CELL; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; INNATE IMMUNITY; LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PLASMID; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN INTERACTION; PROTEIN LOCALIZATION; REAL TIME POLYMERASE CHAIN REACTION; RNA INTERFERENCE; UPREGULATION; VIRUS REPLICATION; CELL LINE; GENETICS; HEPACIVIRUS; HEPATITIS C; IMMUNOLOGY; ISOLATION AND PURIFICATION; LIVER CELL; LIVER CELL CARCINOMA; LIVER TUMOR; METABOLISM; VIROLOGY;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANTIVIRAL AGENTS; CARCINOMA, HEPATOCELLULAR; CELL LINE; HEPACIVIRUS; HEPATITIS C; HEPATOCYTES; HUMANS; INTERFERON-BETA; INTERFERONS; LIVER NEOPLASMS; MEMBRANE PROTEINS; TNF RECEPTOR-ASSOCIATED FACTOR 6; VIRUS REPLICATION;

EID: 85018286074     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1006321     Document Type: Article

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