Adiposity amplifies the genetic risk of fatty liver disease conferred by multiple loci

Nature Genetics

Volumn 49, Issue 6, 2017, Pages 842-847

  Stender, Stefan ^a,b   Kozlitina, Julia ^a   Nordestgaard, Børge G ^c,d   Tybjærg Hansen, Anne ^b,c,d   Hobbs, Helen H ^a   Cohen, Jonathan C ^e  

^a UNIVERSITY OF TEXAS AT DALLAS   (United States)

^b University of Copenhagen   (Denmark)

^c GENTOFTE UNIVERSITY HOSPITAL   (Denmark)

^d FREDERIKSBERG HOSPITAL   (Denmark)

^e UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

LIVER ENZYME; ADIPONUTRIN, HUMAN; ALANINE AMINOTRANSFERASE; GCKR PROTEIN, HUMAN; MEMBRANE PROTEIN; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TM6SF2 PROTEIN, HUMAN; TRIACYLGLYCEROL; TRIACYLGLYCEROL LIPASE;

ARTICLE; BODY MASS; GCKR GENE; GENE; GENE AMPLIFICATION; GENE FREQUENCY; GENE INTERACTION; GENE LOCUS; GENE SEQUENCE; GENETIC CODE; GENETIC RISK; GENETIC SUSCEPTIBILITY; GENETIC VARIABILITY; GENOTYPE; GENOTYPE ENVIRONMENT INTERACTION; LIVER CIRRHOSIS; MENDELIAN RANDOMIZATION ANALYSIS; NONALCOHOLIC FATTY LIVER; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OBESITY; PNPLA3 GENE; PRIORITY JOURNAL; TM6SF2 GENE; BLOOD; CLINICAL TRIAL; COHORT ANALYSIS; GENETIC PREDISPOSITION; GENETICS; HUMAN; MULTICENTER STUDY; SINGLE NUCLEOTIDE POLYMORPHISM;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADIPOSITY; ALANINE TRANSAMINASE; COHORT STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; LIPASE; MEMBRANE PROTEINS; NON-ALCOHOLIC FATTY LIVER DISEASE; POLYMORPHISM, SINGLE NUCLEOTIDE; TRIGLYCERIDES;

EID: 85018256652     PISSN: 10614036     EISSN: 15461718     Source Type: Journal    
DOI: 10.1038/ng.3855     Document Type: Article

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