The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent

Gastroenterology

Volumn 150, Issue 5, 2016, Pages 1219-1230.e6

  Mancina, Rosellina Margherita ^a   Dongiovanni, Paola ^b   Petta, Salvatore ^c   Pingitore, Piero ^a   Meroni, Marica ^d   Rametta, Raffaela ^d   Borén, Jan ^a   Montalcini, Tiziana ^e   Pujia, Arturo ^e   Wiklund, Olov ^a,f   Hindy, George ^g   Spagnuolo, Rocco ^e   Motta, Benedetta Maria ^a   Pipitone, Rosaria Maria ^d   Craxì, Antonio ^c   Fargion, Silvia ^b,d   Nobili, Valerio ^h   Käkelä, Pirjo ⁱ   Kärjä, Vesa ⁱ   Männistö, Ville ⁱ   Pihlajamäki, Jussi ^i,j   Reilly, Dermot F ^k   Castro Perez, Jose ^k,l   Kozlitina, Julia ^m   Valenti, Luca ^b,d   Romeo, Stefano ^a,e,f   more..

^a UNIVERSITY OF GOTHENBURG   (Sweden)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c UNIVERSITY OF PALERMO   (Italy)

^d UNIVERSITY OF MILAN   (Italy)

^e UNIVERSITY MAGNA GRAECIA OF CATANZARO   (Italy)

^f SAHLGRENSKA UNIVERSITY HOSPITAL   (Sweden)

^g Diabetes and Cardiovascular Disease Genetic Epidemiology   (Sweden)

^h BAMBINO GESÙ CHILDREN S HOSPITAL   (Italy)

ⁱ KUOPIO UNIVERSITY HOSPITAL   (Finland)

^j UNIVERSITY OF EASTERN FINLAND   (Finland)

^k MERCK RESEARCH LABORATORIES   (United States)

^l WATERS CORPORATION   (United States)

^m UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

more..

Author keywords

Arachidonic Acid; NASH; PNPLA3; TM6SF2

Indexed keywords

FAT DROPLET; PHOSPHATIDYLINOSITOL; TRIACYLGLYCEROL; ACYLTRANSFERASE; MBOAT7 PROTEIN, HUMAN; MEMBRANE PROTEIN; TMC4 PROTEIN, HUMAN;

AFRICAN AMERICAN; ALLELE; ANTHROPOMETRY; ARTICLE; BIOCHEMICAL ANALYSIS; CONTROLLED STUDY; DISEASE SEVERITY; ENDOPLASMIC RETICULUM; EUROPEAN; EUROPEAN AMERICAN; FAT CONTENT; FATTY LIVER; FEMALE; GENE; GENE LOCUS; GENETIC ASSOCIATION; GENETIC VARIABILITY; GENOTYPE; HEREDITY; HISPANIC; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN TISSUE; LIPIDOMICS; LIVER BIOPSY; LIVER FIBROSIS; LIVER INJURY; MAJOR CLINICAL STUDY; MALE; MEMBRANE O ACYLTRANSFERASE DOMAIN-CONTAINING 7 GENE; MITOCHONDRION; NONALCOHOLIC FATTY LIVER; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTON NUCLEAR MAGNETIC RESONANCE; TRANSMEMBRANE CHANNEL LIKE 4 GENE; BIOPSY; CASE CONTROL STUDY; CAUCASIAN; CLINICAL TRIAL; CROSS-SECTIONAL STUDY; EPIDEMIOLOGY; ETHNOLOGY; EUROPE; GENETIC POLYMORPHISM; GENETIC PREDISPOSITION; GENETICS; GENOME-WIDE ASSOCIATION STUDY; LIVER; LIVER CIRRHOSIS; METABOLISM; MULTICENTER STUDY; NON-ALCOHOLIC FATTY LIVER DISEASE; PATHOLOGY; PHENOTYPE; RISK FACTOR; SEVERITY OF ILLNESS INDEX; TEXAS;

ACETYLTRANSFERASES; ACYLTRANSFERASES; BIOPSY; CASE-CONTROL STUDIES; CROSS-SECTIONAL STUDIES; EUROPE; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENOME-WIDE ASSOCIATION STUDY; HUMANS; LIVER; LIVER CIRRHOSIS; MALE; MEMBRANE PROTEINS; NON-ALCOHOLIC FATTY LIVER DISEASE; PHENOTYPE; PHOSPHATIDYLINOSITOLS; POLYMORPHISM, GENETIC; PROTON MAGNETIC RESONANCE SPECTROSCOPY; RISK FACTORS; SEVERITY OF ILLNESS INDEX; TEXAS; TRIGLYCERIDES;

EID: 84964334172     PISSN: 00165085     EISSN: 15280012     Source Type: Journal    
DOI: 10.1053/j.gastro.2016.01.032     Document Type: Article

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