Peptide-Boronic Acid Inhibitors of Flaviviral Proteases: Medicinal Chemistry and Structural Biology

Journal of Medicinal Chemistry

Volumn 60, Issue 1, 2017, Pages 511-516

  Nitsche, Christoph ^a   Zhang, Linlin ^b,c   Weigel, Lena F ^a   Schilz, Jonas ^b   Graf, Dominik ^a   Bartenschlager, Ralf ^a,c   Hilgenfeld, Rolf ^b,c   Klein, Christian D ^a  

^a UNIVERSITY OF HEIDELBERG   (Germany)

^b UNIVERSITY OF LÜBECK   (Germany)

^c German Centre for Infection Research (DZIF)   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIVIRUS AGENT; BORONIC ACID DERIVATIVE; PROTEINASE INHIBITOR; PEPTIDE;

ANTIVIRAL ACTIVITY; ARTICLE; BINDING AFFINITY; CRYSTAL STRUCTURE; DENGUE VIRUS; DRUG STRUCTURE; DRUG SYNTHESIS; MEDICINAL CHEMISTRY; VIRUS INHIBITION; VIRUS REPLICATION; WEST NILE VIRUS; ZIKA VIRUS; CARBON NUCLEAR MAGNETIC RESONANCE; CHEMISTRY; DRUG EFFECTS; ELECTROSPRAY MASS SPECTROMETRY; ENZYMOLOGY; FLAVIVIRUS; PROTON NUCLEAR MAGNETIC RESONANCE; STRUCTURE ACTIVITY RELATION;

ANTIVIRAL AGENTS; BORONIC ACIDS; CARBON-13 MAGNETIC RESONANCE SPECTROSCOPY; FLAVIVIRUS; PEPTIDES; PROTEASE INHIBITORS; PROTON MAGNETIC RESONANCE SPECTROSCOPY; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 85018193437     PISSN: 00222623     EISSN: 15204804     Source Type: Journal    
DOI: 10.1021/acs.jmedchem.6b01021     Document Type: Article

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