SCOPUS 정보 검색 플랫폼

Volumn 12, Issue 8, 2017, Pages 613-620

Elongated and Shortened Peptidomimetic Inhibitors of the Proprotein Convertase Furin

(9) Hardes, Kornelia a Ivanova, Teodora a Thaa, Bastian b McInerney, Gerald M b Klokk, Tove Irene c Sandvig, Kirsten c Künzel, Sebastian d Lindberg, Iris e Steinmetzer, Torsten a

a PHILIPPS UNIVERSITY MARBURG (Germany)

b KAROLINSKA INSTITUTE (Sweden)

c OSLO UNIVERSITY HOSPITAL (Norway)

d Hochschule Ansbach (Germany)

e UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE (United States)

Author keywords

alphaviruses; chikungunya virus; diphtheria toxin; furin; inhibitors; Semliki Forest virus

Indexed keywords

AMIDE; ANTITOXIN; ANTIVIRUS AGENT; DIPHTHERIA TOXIN; FURIN; PEPTIDOMIMETIC AGENT; PROPROTEIN CONVERTASE FURIN INHIBITOR; SERINE PROTEINASE INHIBITOR; UNCLASSIFIED DRUG; BENZAMIDE DERIVATIVE; OLIGOPEPTIDE;

ALPHAVIRUS; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANTIVIRAL ACTIVITY; ARTICLE; BHK CELL LINE; CHIKUNGUNYA VIRUS; CONTROLLED STUDY; DRUG DESIGN; MOLECULAR WEIGHT; NEWBORN; NONHUMAN; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; SEMLIKI FOREST VIRUS; SOLID PHASE SYNTHESIS; ANIMAL; ANTAGONISTS AND INHIBITORS; CELL LINE; CHLOROCEBUS AETHIOPS; DRUG EFFECTS; HAMSTER; METABOLISM; SYNTHESIS;

ANIMALS; ANTIVIRAL AGENTS; BENZAMIDES; CELL LINE; CERCOPITHECUS AETHIOPS; CHIKUNGUNYA VIRUS; CRICETINAE; DIPHTHERIA TOXIN; FURIN; OLIGOPEPTIDES; PEPTIDOMIMETICS; SEMLIKI FOREST VIRUS; SERINE PROTEINASE INHIBITORS;

EID: 85017403687 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201700108 Document Type: Article

Times cited : (18)

References (43)

1
- 0036791359
- G. Thomas, Nat. Rev. Mol. Cell Biol. 2002, 3, 753–766.
- (2002) Nat. Rev. Mol. Cell Biol. , vol.3 , pp. 753-766
- Thomas, G.¹

2
- 0036882391
- N. C. Rockwell, D. J. Krysan, T. Komiyama, R. S. Fuller, Chem. Rev. 2002, 102, 4525–4548.
- (2002) Chem. Rev. , vol.102 , pp. 4525-4548
- Rockwell, N.C.¹ Krysan, D.J.² Komiyama, T.³ Fuller, R.S.⁴

3
- 54349103245
- M. Chrétien, N. G. Seidah, A. Basak, M. Mbikay, Expert Opin. Ther. Targets 2008, 12, 1289–1300.
- (2008) Expert Opin. Ther. Targets , vol.12 , pp. 1289-1300
- Chrétien, M.¹ Seidah, N.G.² Basak, A.³ Mbikay, M.⁴

4
- 84860383419
- N. G. Seidah, A. Prat, Nat. Rev. Drug Discovery 2012, 11, 367–383.
- (2012) Nat. Rev. Drug Discovery , vol.11 , pp. 367-383
- Seidah, N.G.¹ Prat, A.²

5
- 84860380797
- F. Couture, F. D′Anjou, R. Day, Biomol. Concepts 2011, 2, 421–438.
- (2011) Biomol. Concepts , vol.2 , pp. 421-438
- Couture, F.¹ D′Anjou, F.² Day, R.³

6
- 84878237040
- A. Pasquato, R. da Palma, J. C. Galan, N. G. Seidah, S. Kunz, Antiviral Res. 2013, 99, 49–60.
- (2013) Antiviral Res. , vol.99 , pp. 49-60
- Pasquato, A.¹ da Palma, R.² Galan, J.C.³ Seidah, N.G.⁴ Kunz, S.⁵

7
- 19944414287
- A. J. M. Roebroek, N. A. Taylor, E. Louagie, I. Pauli, L. Smeijers, A. Snellinx, A. Lauwers, W. J. M. Van de Ven, D. Hartmann, J. W. M. Creemers, J. Biol. Chem. 2004, 279, 53442–53450.
- (2004) J. Biol. Chem. , vol.279 , pp. 53442-53450
- Roebroek, A.J.M.¹ Taylor, N.A.² Louagie, E.³ Pauli, I.⁴ Smeijers, L.⁵ Snellinx, A.⁶ Lauwers, A.⁷ Ven, W.J.M.V.D.⁸ Hartmann, D.⁹ Creemers, J.W.M.¹⁰

8
- 0036893450
- M. S. Sarac, A. Cameron, I. Lindberg, Infect. Immun. 2002, 70, 7136–7139;
- (2002) Infect. Immun. , vol.70 , pp. 7136-7139
- Sarac, M.S.¹ Cameron, A.² Lindberg, I.³

9
- 0346881395
- M. S. Sarac, J. R. Peinado, S. H. Leppla, I. Lindberg, Infect. Immun. 2004, 72, 602–605.
- (2004) Infect. Immun. , vol.72 , pp. 602-605
- Sarac, M.S.¹ Peinado, J.R.² Leppla, S.H.³ Lindberg, I.⁴

10
- 27744541223
- A. Basak, J. Mol. Med. 2005, 83, 844–855.
- (2005) J. Mol. Med. , vol.83 , pp. 844-855
- Basak, A.¹

11
- 85043745348
- Morgan & Claypool, San Rafael
- U. Chandra De, P. Mishra, P. Rudra Pal, B. Dinda, A. Basak, Non-Peptide Inhibitors of Proprotein Convertase Subtilisin Kexins (PCSKS): An Overall Review of Existing and New Data, Morgan & Claypool, San Rafael, 2012.
- (2012) Non-Peptide Inhibitors of Proprotein Convertase Subtilisin Kexins (PCSKS): An Overall Review of Existing and New Data
- Chandra De, U.¹ Mishra, P.² Rudra Pal, P.³ Dinda, B.⁴ Basak, A.⁵

12
- 77249117734
- G. L. Becker, F. Sielaff, M. E. Than, I. Lindberg, S. Routhier, R. Day, Y. Lu, W. Garten, T. Steinmetzer, J. Med. Chem. 2010, 53, 1067–1075.
- (2010) J. Med. Chem. , vol.53 , pp. 1067-1075
- Becker, G.L.¹ Sielaff, F.² Than, M.E.³ Lindberg, I.⁴ Routhier, S.⁵ Day, R.⁶ Lu, Y.⁷ Garten, W.⁸ Steinmetzer, T.⁹

13
- 79960914019
- G. L. Becker, K. Hardes, T. Steinmetzer, Bioorg. Med. Chem. Lett. 2011, 21, 4695–4697.
- (2011) Bioorg. Med. Chem. Lett. , vol.21 , pp. 4695-4697
- Becker, G.L.¹ Hardes, K.² Steinmetzer, T.³

14
- 84933502451
- K. Hardes, G. L. Becker, Y. Lu, S. O. Dahms, S. Köhler, W. Beyer, K. Sandvig, H. Yamamoto, I. Lindberg, L. Walz, V. von Messling, M. E. Than, W. Garten, T. Steinmetzer, ChemMedChem 2015, 10, 1218–1231.
- (2015) ChemMedChem , vol.10 , pp. 1218-1231
- Hardes, K.¹ Becker, G.L.² Lu, Y.³ Dahms, S.O.⁴ Köhler, S.⁵ Beyer, W.⁶ Sandvig, K.⁷ Yamamoto, H.⁸ Lindberg, I.⁹ Walz, L.¹⁰ von Messling, V.¹¹ Than, M.E.¹² Garten, W.¹³ Steinmetzer, T.¹⁴

15
- 84900838688
- S. O. Dahms, K. Hardes, G. L. Becker, T. Steinmetzer, H. Brandstetter, M. E. Than, ACS Chem. Biol. 2014, 9, 1113–1118.
- (2014) ACS Chem. Biol. , vol.9 , pp. 1113-1118
- Dahms, S.O.¹ Hardes, K.² Becker, G.L.³ Steinmetzer, T.⁴ Brandstetter, H.⁵ Than, M.E.⁶

16
- 84989950483
- S. O. Dahms, M. Arciniega, T. Steinmetzer, R. Huber, M. E. Than, Proc. Natl. Acad. Sci. USA 2016, 113, 11196–11201.
- (2016) Proc. Natl. Acad. Sci. USA , vol.113 , pp. 11196-11201
- Dahms, S.O.¹ Arciniega, M.² Steinmetzer, T.³ Huber, R.⁴ Than, M.E.⁵

17
- 84862644095
- G. L. Becker, Y. Lu, K. Hardes, B. Strehlow, C. Levesque, I. Lindberg, K. Sandvig, U. Bakowsky, R. Day, W. Garten, T. Steinmetzer, J. Biol. Chem. 2012, 287, 21992–22003.
- (2012) J. Biol. Chem. , vol.287 , pp. 21992-22003
- Becker, G.L.¹ Lu, Y.² Hardes, K.³ Strehlow, B.⁴ Levesque, C.⁵ Lindberg, I.⁶ Sandvig, K.⁷ Bakowsky, U.⁸ Day, R.⁹ Garten, W.¹⁰ Steinmetzer, T.¹¹

18
- 4344716372
- M. M. Kacprzak, J. R. Peinado, M. E. Than, J. Appel, S. Henrich, G. Lipkind, R. A. Houghten, W. Bode, I. Lindberg, J. Biol. Chem. 2004, 279, 36788–36794.
- (2004) J. Biol. Chem. , vol.279 , pp. 36788-36794
- Kacprzak, M.M.¹ Peinado, J.R.² Than, M.E.³ Appel, J.⁴ Henrich, S.⁵ Lipkind, G.⁶ Houghten, R.A.⁷ Bode, W.⁸ Lindberg, I.⁹

19
- 84892624432
- H. Gagnon, S. Beauchemin, A. Kwiatkowska, F. Couture, F. D′Anjou, C. Levesque, F. Dufour, A. R. Desbiens, R. Vaillancourt, S. Bernard, R. Desjardins, F. Malouin, Y. L. Dory, R. Day, J. Med. Chem. 2014, 57, 29–41.
- (2014) J. Med. Chem. , vol.57 , pp. 29-41
- Gagnon, H.¹ Beauchemin, S.² Kwiatkowska, A.³ Couture, F.⁴ D′Anjou, F.⁵ Levesque, C.⁶ Dufour, F.⁷ Desbiens, A.R.⁸ Vaillancourt, R.⁹ Bernard, S.¹⁰ Desjardins, R.¹¹ Malouin, F.¹² Dory, Y.L.¹³ Day, R.¹⁴

20
- 0025969299
- F. J. Hock, K. Wirth, U. Albus, W. Linz, H. J. Gerhards, G. Wiemer, S. Henke, G. Breipohl, W. Konig, J. Knolle, Br. J. Pharmacol. 1991, 102, 769–773;
- (1991) Br. J. Pharmacol. , vol.102 , pp. 769-773
- Hock, F.J.¹ Wirth, K.² Albus, U.³ Linz, W.⁴ Gerhards, H.J.⁵ Wiemer, G.⁶ Henke, S.⁷ Breipohl, G.⁸ Konig, W.⁹ Knolle, J.¹⁰

21
- 20244363204
- K. Wirth, F. J. Hock, U. Albus, W. Linz, H. G. Alpermann, H. Anagnostopoulos, S. Henk, G. Breipohl, W. Konig, J. Knolle, Br. J. Pharmacol. 1991, 102, 774–777.
- (1991) Br. J. Pharmacol. , vol.102 , pp. 774-777
- Wirth, K.¹ Hock, F.J.² Albus, U.³ Linz, W.⁴ Alpermann, H.G.⁵ Anagnostopoulos, H.⁶ Henk, S.⁷ Breipohl, G.⁸ Konig, W.⁹ Knolle, J.¹⁰

22
- 23944514165
- John Wiley & Sons, Hoboken
- R. A. Copeland, Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists, John Wiley & Sons, Hoboken, 2005.
- (2005) Evaluation of Enzyme Inhibitors in Drug Discovery: A Guide for Medicinal Chemists and Pharmacologists
- Copeland, R.A.¹

23
- 84892609855
- A. Kwiatkowska, F. Couture, C. Levesque, K. Ly, R. Desjardins, S. Beauchemin, A. Prahl, B. Lammek, W. Neugebauer, Y. L. Dory, R. Day, J. Med. Chem. 2014, 57, 98–109.
- (2014) J. Med. Chem. , vol.57 , pp. 98-109
- Kwiatkowska, A.¹ Couture, F.² Levesque, C.³ Ly, K.⁴ Desjardins, R.⁵ Beauchemin, S.⁶ Prahl, A.⁷ Lammek, B.⁸ Neugebauer, W.⁹ Dory, Y.L.¹⁰ Day, R.¹¹

24
- 84957558906
- A. Kwiatkowska, F. Couture, C. Levesque, K. Ly, S. Beauchemin, R. Desjardins, W. Neugebauer, Y. L. Dory, R. Day, ChemMedChem 2016, 11, 289–301.
- (2016) ChemMedChem , vol.11 , pp. 289-301
- Kwiatkowska, A.¹ Couture, F.² Levesque, C.³ Ly, K.⁴ Beauchemin, S.⁵ Desjardins, R.⁶ Neugebauer, W.⁷ Dory, Y.L.⁸ Day, R.⁹

25
- 84934890156
- Y. Lu, K. Hardes, S. O. Dahms, E. Böttcher-Friebertshäuser, T. Steinmetzer, M. E. Than, H.-D. Klenk, W. Garten, Antiviral Res. 2015, 120, 89–100.
- (2015) Antiviral Res. , vol.120 , pp. 89-100
- Lu, Y.¹ Hardes, K.² Dahms, S.O.³ Böttcher-Friebertshäuser, E.⁴ Steinmetzer, T.⁵ Than, M.E.⁶ Klenk, H.-D.⁷ Garten, W.⁸

26
- 70349199877
- J. Jose, J. E. Snyder, R. J. Kuhn, Future Microbiol. 2009, 4, 837–856.
- (2009) Future Microbiol. , vol.4 , pp. 837-856
- Jose, J.¹ Snyder, J.E.² Kuhn, R.J.³

27
- 0037369080
- X. Zhang, M. Fugère, R. Day, M. Kielian, J. Virol. 2003, 77, 2981–2989.
- (2003) J. Virol. , vol.77 , pp. 2981-2989
- Zhang, X.¹ Fugère, M.² Day, R.³ Kielian, M.⁴

28
- 52049086033
- S. Ozden, M. Lucas-Hourani, P.-E. Ceccaldi, A. Basak, M. Valentine, S. Benjannet, J. Hamelin, Y. Jacob, K. Mamchaoui, V. Mouly, P. Desprès, A. Gessain, G. Butler-Browne, M. Chrétien, F. Tangy, P.-O. Vidalain, N. G. Seidah, J. Biol. Chem. 2008, 283, 21899–21908.
- (2008) J. Biol. Chem. , vol.283 , pp. 21899-21908
- Ozden, S.¹ Lucas-Hourani, M.² Ceccaldi, P.-E.³ Basak, A.⁴ Valentine, M.⁵ Benjannet, S.⁶ Hamelin, J.⁷ Jacob, Y.⁸ Mamchaoui, K.⁹ Mouly, V.¹⁰ Desprès, P.¹¹ Gessain, A.¹² Butler-Browne, G.¹³ Chrétien, M.¹⁴ Tangy, F.¹⁵ Vidalain, P.-O.¹⁶ Seidah, N.G.¹⁷

29
- 0034051194
- S, –S
- T. L. Hadfield, P. McEvoy, Y. Polotsky, V. A. Tzinserling, A. A. Yakovlev, J. Infect. Dis. 2000, 181, S116–S120.
- (2000) J. Infect. Dis. , vol.181 , pp. 116-120
- Hadfield, T.L.¹ McEvoy, P.² Polotsky, Y.³ Tzinserling, V.A.⁴ Yakovlev, A.A.⁵

30
- 0027495717
- M. Tsuneoka, K. Nakayama, K. Hatsuzawa, M. Komada, N. Kitamura, E. Mekada, J. Biol. Chem. 1993, 268, 26461–26465.
- (1993) J. Biol. Chem. , vol.268 , pp. 26461-26465
- Tsuneoka, M.¹ Nakayama, K.² Hatsuzawa, K.³ Komada, M.⁴ Kitamura, N.⁵ Mekada, E.⁶

31
- 0034878448
- R. J. Collier, Toxicon 2001, 39, 1793–1803.
- (2001) Toxicon , vol.39 , pp. 1793-1803
- Collier, R.J.¹

32
- 84863221458
- F. López-Vallejo, K. Martinez-Mayorga, Bioorg. Med. Chem. 2012, 20, 4462–4471.
- (2012) Bioorg. Med. Chem. , vol.20 , pp. 4462-4471
- López-Vallejo, F.¹ Martinez-Mayorga, K.²

33
- 84870985285
- C. Levesque, M. Fugère, A. Kwiatkowska, F. Couture, R. Desjardins, S. Routhier, P. Moussette, A. Prahl, B. Lammek, J. R. Appel, R. A. Houghten, F. D'Anjou, Y. L. Dory, W. Neugebauer, R. Day, J. Med. Chem. 2012, 55, 10501–10511.
- (2012) J. Med. Chem. , vol.55 , pp. 10501-10511
- Levesque, C.¹ Fugère, M.² Kwiatkowska, A.³ Couture, F.⁴ Desjardins, R.⁵ Routhier, S.⁶ Moussette, P.⁷ Prahl, A.⁸ Lammek, B.⁹ Appel, J.R.¹⁰ Houghten, R.A.¹¹ D'Anjou, F.¹² Dory, Y.L.¹³ Neugebauer, W.¹⁴ Day, R.¹⁵

34
- 33747300527
- S. M. Fuchs, R. T. Raines, Cell. Mol. Life Sci. 2006, 63, 1819–1822;
- (2006) Cell. Mol. Life Sci. , vol.63 , pp. 1819-1822
- Fuchs, S.M.¹ Raines, R.T.²

35
- 78651226718
- S. Katayama, H. Hirose, K. Takayama, I. Nakase, S. Futaki, J. Controlled Release 2011, 149, 29–35.
- (2011) J. Controlled Release , vol.149 , pp. 29-35
- Katayama, S.¹ Hirose, H.² Takayama, K.³ Nakase, I.⁴ Futaki, S.⁵

36
- 58249087702
- P. Karicherla, J. A. Hobden, Invest. Ophthalmol. Visual Sci. 2009, 50, 256–262;
- (2009) Invest. Ophthalmol. Visual Sci. , vol.50 , pp. 256-262
- Karicherla, P.¹ Hobden, J.A.²

37
- 77950838153
- P. Karicherla, J. A. Hobden, Curr. Eye Res. 2010, 35, 220–224.
- (2010) Curr. Eye Res. , vol.35 , pp. 220-224
- Karicherla, P.¹ Hobden, J.A.²

38
- 33751391460
- M. S. Bernatowicz, Y. Wu, G. R. Matsueda, J. Org. Chem. 1992, 57, 2497–2502.
- (1992) J. Org. Chem. , vol.57 , pp. 2497-2502
- Bernatowicz, M.S.¹ Wu, Y.² Matsueda, G.R.³

39
- 0018699952
- J. W. Williams, J. F. Morrison, Methods Enzymol. 1979, 63, 437–467.
- (1979) Methods Enzymol. , vol.63 , pp. 437-467
- Williams, J.W.¹ Morrison, J.F.²

40
- 0025912001
- P. Liljeström, S. Lusa, D. Huylebroeck, H. Garoff, J. Virol. 1991, 65, 4107–4113.
- (1991) J. Virol. , vol.65 , pp. 4107-4113
- Liljeström, P.¹ Lusa, S.² Huylebroeck, D.³ Garoff, H.⁴

41
- 33749553499
- I. M. Cristea, J.-W. N. Carroll, M. P. Rout, C. M. Rice, B. T. Chait, M. R. MacDonald, J. Biol. Chem. 2006, 281, 30269–30278.
- (2006) J. Biol. Chem. , vol.281 , pp. 30269-30278
- Cristea, I.M.¹ Carroll, J.-W.N.² Rout, M.P.³ Rice, C.M.⁴ Chait, B.T.⁵ MacDonald, M.R.⁶

42
- 83655212354
- e
- L. Pohjala, A. Utt, M. Varjak, A. Lulla, A. Merits, T. Ahola, P. Tammela, PLoS One 2011, 6, e28923.
- (2011) PLoS One , vol.6
- Pohjala, L.¹ Utt, A.² Varjak, M.³ Lulla, A.⁴ Merits, A.⁵ Ahola, T.⁶ Tammela, P.⁷

43
- 34247177028
- A. Kurmanova, A. Llorente, A. Polesskaya, O. Garred, S. Olsnes, J. Kozlov, K. Sandvig, Biochem. Biophys. Res. Commun. 2007, 357, 144–149.
- (2007) Biochem. Biophys. Res. Commun. , vol.357 , pp. 144-149
- Kurmanova, A.¹ Llorente, A.² Polesskaya, A.³ Garred, O.⁴ Olsnes, S.⁵ Kozlov, J.⁶ Sandvig, K.⁷

* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.