SCOPUS 정보 검색 플랫폼

Volumn 11, Issue 3, 2016, Pages 289-301

Novel Insights into Structure-Activity Relationships of N-Terminally Modified PACE4 Inhibitors

(9) Kwiatkowska, Anna a Couture, Frédéric a Levesque, Christine a Ly, Kévin a Beauchemin, Sophie a Desjardins, Roxane a Neugebauer, Witold a Dory, Yves L a Day, Robert a

a UNIVERSITÉ DE SHERBROOKE (Canada)

Author keywords

enzyme inhibitors; PACE4; proprotein convertases; prostate cancer; structure activity relationships

Indexed keywords

FURIN; MACROGOL; OCTAPEPTIDE; PACE 4 INHIBITOR; PACE 4 PROTEIN; SERINE PROTEINASE; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ENZYME INHIBITOR; PCSK6 PROTEIN, HUMAN; PEPTIDE;

AMINO TERMINAL SEQUENCE; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; BINDING AFFINITY; CELL MEMBRANE PERMEABILITY; CELL PROLIFERATION; CYTOTOXICITY; DRUG HALF LIFE; DRUG PENETRATION; ENZYMATIC DEGRADATION; HUMAN; HUMAN CELL; IN VIVO STUDY; MALE; MAXIMUM TOLERATED DOSE; PEPTIDE SYNTHESIS; PRIORITY JOURNAL; PROSTATE CANCER CELL LINE; RENAL CLEARANCE; STEREOSPECIFICITY; STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; ANIMAL; ANTAGONISTS AND INHIBITORS; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; DRUG SCREENING; INBRED MOUSE STRAIN; INTRAVENOUS DRUG ADMINISTRATION; METABOLISM; MOUSE; NEOPLASMS, EXPERIMENTAL; PATHOLOGY; TUMOR CELL LINE;

ADMINISTRATION, INTRAVENOUS; AMINO ACID SEQUENCE; ANIMALS; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CELL PROLIFERATION; DRUG SCREENING ASSAYS, ANTITUMOR; ENZYME INHIBITORS; HUMANS; MICE; MICE, INBRED STRAINS; MOLECULAR STRUCTURE; NEOPLASMS, EXPERIMENTAL; PEPTIDES; PROPROTEIN CONVERTASES; SERINE ENDOPEPTIDASES; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84957558906 PISSN: 18607179 EISSN: 18607187 Source Type: Journal
DOI: 10.1002/cmdc.201500532 Document Type: Article

Times cited : (14)

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