Inhibition of Chikungunya virus infection in cultured human muscle cells by furin inhibitors: Impairment of the maturation of the E2 surface glycoprotein

Journal of Biological Chemistry

Volumn 283, Issue 32, 2008, Pages 21899-21908

  Ozden, Simona ^a   Lucas Hourani, Marianne ^a   Ceccaldi, Pierre Emmanuel ^a   Basak, Ajoy ^b   Valentine, Menogh ^b   Benjannet, Suzanne ^c   Hamelin, Josée ^c   Jacob, Yves ^a   Mamchaoui, Kamel ^d,e   Mouly, Vincent ^d,e   Desprès, Philippe ^a   Gessain, Antoine ^a   Butler Browne, Gillian ^d,e   Chrétien, Michel ^c   Tangy, Frédéric ^a   Vidalain, Pierre Olivier ^a   Seidah, Nabil G ^c  

^a INSTITUT PASTEUR   (France)

^b OTTAWA HOSPITAL RESEARCH INSTITUTE   (Canada)

^c CLIN RESEARCH INSTITUTE OF MONTREAL   (Canada)

^d SORBONNE UNIVERSITÉ   (France)

^e PITIÉ SALPÊTRIÈRE HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BIOMOLECULES; CELL CULTURE; KETONES; PEPTIDES; VIRUSES;

INFECTED CELLS; MYOBLAST CELLS; NATURAL TARGETS; NEW APPROACHES; PRECURSOR PROTEINS; RECEPTOR BINDING; SURFACE GLYCOPROTEINS; VIRUS INFECTION;

CELLS;

CHLOROQUINE; COMPLEMENTARY DNA; DECANOYLARGINYLVALYLLYSYLARGININE CHLOROMETHYL KETONE; FURIN; GENOMIC RNA; GLYCOPROTEIN E2; RECOMBINANT PROTEIN; SYNTHETIC PEPTIDE; UNCLASSIFIED DRUG; VIRUS ENVELOPE PROTEIN; VIRUS GLYCOPROTEIN; ANTIMALARIAL AGENT; DECANOYLRVKRCHLOROMETHYLKETONE; PEPTIDE CHLOROMETHYL KETONE; PROTEIN SYNTHESIS INHIBITOR; SERINE PROTEINASE;

ARTICLE; ASIA; CELL CULTURE; CHIKUNGUNYA ALPHAVIRUS; CONTROLLED STUDY; DRUG TARGETING; ENZYME KINETICS; FEVER; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR CLONING; MOSQUITO; MUSCLE CELL; NONHUMAN; NUCLEOTIDE SEQUENCE; OPEN READING FRAME; PEPTIDE SYNTHESIS; PLASMID; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; REVERSED PHASE HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; STRAIN IDENTIFICATION; VIRUS CELL INTERACTION; VIRUS INFECTION; VIRUS INHIBITION; VIRUS PARTICLE; VIRUS TRANSMISSION; WESTERN BLOTTING; CELL LINE; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENZYMOLOGY; METABOLISM; MYOBLAST; PHYSIOLOGY; VIROLOGY; VIRUS ENTRY; VIRUS REPLICATION;

ALPHAVIRUS; CHIKUNGUNYA VIRUS;

ALPHAVIRUS INFECTIONS; AMINO ACID CHLOROMETHYL KETONES; ANTIMALARIALS; CELL LINE; CHIKUNGUNYA VIRUS; CHLOROQUINE; FURIN; HUMANS; MYOBLASTS; PROPROTEIN CONVERTASES; PROTEIN SYNTHESIS INHIBITORS; VIRAL ENVELOPE PROTEINS; VIRUS INTERNALIZATION; VIRUS REPLICATION;

EID: 52049086033     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M802444200     Document Type: Article

References (46)

1. Weaver, S. C., and Frolov, I. V. (2005) in Topley and Wilson's Microbiology & Microbial Infections; Virology (Mahy, B., and ter Meulen, V., eds), 10th Ed., Hodder Arnold, London
2. Mohan, A. (2006) Indian J. Med. Res. 124, 471-474
3. Charrel, R. N., de Lamballerie, X., and Raoult, D. (2007) N. Engl. J. Med. 356, 769-771
4. Mavalankar, D., Shastri, P., and Raman, P. (2007) Lancet Infect. Dis. 7, 306-307
5. Pialoux, G., Gauzere, B. A., Jaureguiberry, S., and Strobel, M. (2007) Lancet Infect. Dis. 7, 319-327
6. Rezza, G., Nicoletti, L., Angelini, R., Romi, R., Finarelli, A. C., Panning, M., Cordioli, P., Fortuna, C., Boros, S., Magurano, F., Silvi, G., Angelini, P., Dottori, M., Ciufolini, M. G., Majori, G. C., and Cassone, A. (2007) Lancet 370, 1840-1846
7. Ozden, S., Huerre, M., Riviere, J. P., Coffey, L. L., Afonso, P. V., Mouly, V., de Monredon, J., Roger, J. C., El Amrani, M., Yvin, J. L., Jaffar, M. C., Frenkiel, M. P., Sourisseau, M., Schwartz, O., Butler-Browne, G., Despres, P., Gessain, A., and Ceccaldi, P. E. (2007) PLoS ONE 2, e527
8. Couderc, T., Chretien, F., Schilte, C., Disson, O., Brigitte, M., Guivel-Benhassine, F., Touret, Y., Barau, G., Cayet, N., Schuffenecker, I., Despres, P., Arenzana-Seisdedos, F., Michault, A., Albert, M. L., and Lecuit, M. (2008) PLoS Pathog. 4, e29
9. Sourisseau, M., Schilte, C., Casartelli, N., Trouillet, C., Guivel-Benhassine, F., Rudnicka, D., Sol-Foulon, N., Le Roux, K., Prevost, M. C., Fsihi, H., Frenkiel, M. P., Blanchet, F., Afonso, P. V., Ceccaldi, P. E., Ozden, S., Gessain, A., Schuffenecker, I., Verhasselt, B., Zamborlini, A., Saib, A., Rey, F. A., Arenzana-Seisdedos, F., Despres, P., Michault, A., Albert, M. L., and Schwartz, O. (2007) PLoS Pathog. 3, e89
10. Brighton, S. W. (1984) S. Afr. Med. J. 66, 217-218
11. Taubitz, W., Cramer, J. P., Kapaun, A., Pfeffer, M., Drosten, C., Dobler, G., Burchard, G. D., and Loscher, T. (2007) Clin. Infect. Dis. 45, e1-4
12. Savarino, A., Cauda, R., and Cassone, A. (2007) Lancet Infect. Dis. 7, 633
13. Cassell, S., Edwards, J., and Brown, D. T. (1984) J. Virol. 52, 857-864
14. Ferreira, D. F., Santo, M. P., Rebello, M. A., and Rebello, M. C. (2000) J. Med. Microbiol. 49, 313-318
15. Helenius, A., Marsh, M., and White, J. (1982) J. Gen. Virol. 58, 47-61
16. Barr, P. J. (1991) Cell 66, 1-3
17. Seidah, N. G., and Chretien, M. (1999) Brain Res. 848, 45-62
18. Zhang, X., Fugere, M., Day, R., and Kielian, M. (2003) J. Virol. 77, 2981-2989
19. Mayne, J. T., Rice, C. M., Strauss, E. G., Hunkapiller, M. W., and Strauss, J. H. (1984) Virology 134, 338-357
20. Heidner, H. W., and Johnston, R. E. (1994) J. Virol. 68, 8064-8070
21. Heidner, H. W., Knott, T. A., and Johnston, R. E. (1996) J. Virol. 70, 2069-2073
22. Klimstra, W. B., Heidner, H. W., and Johnston, R. E. (1999) J. Virol. 73, 6299-6306
23. Salminen, A., Wahlberg, J. M., Lobigs, M., Liljestrom, P., and Garoff, H. (1992) J. Cell Biol. 116, 349-357
24. Wahlberg, J. M., Bron, R., Wilschut, J., and Garoff, H. (1992) J. Virol. 66, 7309-7318
25. Hallenberger, S., Bosch, V., Angliker, H., Shaw, E., Klenk, H. D., and Garten, W. (1992) Nature 360, 358-361
26. Seidah, N. G., Benjannet, S., Wickham, L., Marcinkiewicz, J., Jasmin, S. B., Stifani, S., Basak, A., Prat, A., and Chretien, M. (2003) Proc. Natl. Acad. Sci. U. S. A. 100, 928-933
27. Bergeron, E., Vincent, M. J., Wickham, L., Hamelin, J., Basak, A., Nichol, S. T., Chretien, M., and Seidah, N. G. (2005) Biochem. Biophys. Res. Commun. 326, 554-563
28. Benjannet, S., Rhainds, D., Hamelin, J., Nassoury, N., and Seidah, N. G. (2006) J. Biol. Chem. 281, 30561-30572
29. Schuffenecker, I., Iteman, I., Michault, A., Murri, S., Frangeul, L., Vaney, M. C., Lavenir, R., Pardigon, N., Reynes, J. M., Pettinelli, F., Biscornet, L., Diancourt, L., Michel, S., Duquerroy, S., Guigon, G., Frenkiel, M. P., Brehin, A. C., Cubito, N., Despres, P., Kunst, F., Rey, F. A., Zeller, H., and Brisse, S. (2006) PLoS Med. 3, e263
30. Zhu, C. H., Mouly, V., Cooper, R. N., Mamchaoui, K., Bigot, A., Shay, J. W., Di Santo, J. P., Butler-Browne, G. S., and Wright, W. E. (2007) Aging Cell 6, 515-523
31. Brehin, A. C., Rubrecht, L., Navarro-Sanchez, M. E., Marechal, V., Frenkiel, M. P., Lapalud, P., Laune, D., Sall, A. A., and Despres, P. (2008) Virology 371, 185-195
32. Basak, S., Mohottalage, D., and Basak, A. (2006) Protein Pept. Lett. 13, 863-876
33. Decroly, E., Wouters, S., Di Bello, C., Lazure, C., Ruysschaert, J. M., and Seidah, N. G. (1996) J. Biol. Chem. 271, 30442-30450
34. Lusson, J., Vieau, D., Hamelin, J., Day, R., Chretien, M., and Seidah, N. G. (1993) Proc. Natl. Acad. Sci. U. S. A. 90, 6691-6695
35. Seidah, N. G., and Prat, A. (2007) J. Mol. Med. 85, 685-696
36. Bergeron, E., Basak, A., Decroly, E., and Seidah, N. G. (2003) Biochem. J. 373, 475-484
37. Feliciangeli, S. F., Thomas, L., Scott, G. K., Subbian, E., Hung, C. H., Molloy, S. S., Jean, F., Shinde, U., and Thomas, G. (2006) J. Biol. Chem. 281, 16108-16116
38. Vincent, M. J., Bergeron, E., Benjannet, S., Erickson, B. R., Rollin, P. E., Ksiazek, T. G., Seidah, N. G., and Nichol, S. T. (2005) Virol. J. 2, 69
39. Powers, A. M., Brault, A. C., Tesh, R. B., and Weaver, S. C. (2000) J. Gen. Virol. 81, 471-479
40. Pasquato, A., and Seidah, N. G. (2008) J. Mol. Neurosci., in press
41. Bolt, G., Pedersen, L. O., and Birkeslund, H. H. (2000) Virus Res. 68, 25-33
42. Stroher, U., Willihnganz, L., Jean, F., and Feldmann, H. (2007) J. Infect. Dis. 196, Suppl. 2, 271-275
43. Decroly, E., Vandenbranden, M., Ruysschaert, J. M., Cogniaux, J., Jacob, G. S., Howard, S. C., Marshall, G., Kompelli, A., Basak, A., and Jean, F. (1994) J. Biol. Chem. 269, 12240-12247
44. Savarino, A., Lucia, M. B., Rastrelli, E., Rutella, S., Golotta, C., Morra, E., Tamburrini, E., Perno, C. F., Boelaert, J. R., Sperber, K., and Cauda, R. (2004) J. Acquir. Immune Defic. Syndr. 35, 223-232
45. Komiyama, T., Swanson, J. A., and Fuller, R. S. (2005) Antimicrob. Agents Chemother. 49, 3875-3882
46. Xiao, Y., Chen, G., Richard, J., Rougeau, N., Li, H., Seidah, N. G., and Cohen, E. A. (2008) Virology 372, 384-397