-
1
-
-
77953642931
-
High-throughput metabolic engineering: Advances in small-molecule screening and selection
-
Dietrich, J. A., McKee, A. E. & Keasling, J. D. High-throughput metabolic engineering: advances in small-molecule screening and selection. Annu. Rev. Biochem. 79, 563-590 (2010).
-
(2010)
Annu. Rev. Biochem.
, vol.79
, pp. 563-590
-
-
Dietrich, J.A.1
McKee, A.E.2
Keasling, J.D.3
-
2
-
-
84859633048
-
Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids
-
Zhang, F., Carothers, J. M. & Keasling, J. D. Design of a dynamic sensor-regulator system for production of chemicals and fuels derived from fatty acids. Nat. Biotechnol. 30, 354-359 (2012).
-
(2012)
Nat. Biotechnol.
, vol.30
, pp. 354-359
-
-
Zhang, F.1
Carothers, J.M.2
Keasling, J.D.3
-
3
-
-
31944447797
-
Transcriptional regulators a la carte: Engineering new effector specificities in bacterial regulatory proteins
-
Galvao, T. C. & de Lorenzo, V. Transcriptional regulators a la carte: engineering new effector specificities in bacterial regulatory proteins. Curr. Opin. Biotechnol. 17, 34-42 (2006).
-
(2006)
Curr. Opin. Biotechnol.
, vol.17
, pp. 34-42
-
-
Galvao, T.C.1
De Lorenzo, V.2
-
4
-
-
42149120662
-
AraC regulatory protein mutants with altered effector specificity
-
Tang, S.-Y., Fazelinia, H. & Cirino, P. C. AraC regulatory protein mutants with altered effector specificity. J. Am. Chem. Soc. 130, 5267-5271 (2008).
-
(2008)
J. Am. Chem. Soc.
, vol.130
, pp. 5267-5271
-
-
Tang, S.-Y.1
Fazelinia, H.2
Cirino, P.C.3
-
5
-
-
84956609810
-
Engineering an allosteric transcription factor to respond to new ligands
-
Taylor, N. D. et al. Engineering an allosteric transcription factor to respond to new ligands. Nat. Methods 13, 177-183 (2016).
-
(2016)
Nat. Methods
, vol.13
, pp. 177-183
-
-
Taylor, N.D.1
-
6
-
-
84935854110
-
Design of an ectoine-responsive AraC mutant and its application in metabolic engineering of ectoine biosynthesis
-
Chen, W. et al. Design of an ectoine-responsive AraC mutant and its application in metabolic engineering of ectoine biosynthesis. Metab. Eng. 30, 149-155 (2015).
-
(2015)
Metab. Eng.
, vol.30
, pp. 149-155
-
-
Chen, W.1
-
7
-
-
79251580632
-
Design and application of a mevalonate-responsive regulatory protein
-
Tang, S.-Y. & Cirino, P. C. Design and application of a mevalonate-responsive regulatory protein. Angew. Chem. Int. Ed. 50, 1084-1086 (2011).
-
(2011)
Angew. Chem. Int. Ed.
, vol.50
, pp. 1084-1086
-
-
Tang, S.-Y.1
Cirino, P.C.2
-
8
-
-
84879999713
-
Screening for enhanced triacetic acid lactone production by recombinant Escherichia coli expressing a designed triacetic acid lactone reporter
-
Tang, S.-Y. et al. Screening for enhanced triacetic acid lactone production by recombinant Escherichia coli expressing a designed triacetic acid lactone reporter. J. Am. Chem. Soc. 135, 10099-10103 (2013).
-
(2013)
J. Am. Chem. Soc.
, vol.135
, pp. 10099-10103
-
-
Tang, S.-Y.1
-
9
-
-
0031961672
-
Lactose repressor protein: Functional properties and structure
-
Matthews, K. S. & Nichols, J. C. Lactose repressor protein: functional properties and structure. Prog. Nucleic Acid Res. Mol. Biol. 58, 127-164 (1998).
-
(1998)
Prog. Nucleic Acid Res. Mol. Biol.
, vol.58
, pp. 127-164
-
-
Matthews, K.S.1
Nichols, J.C.2
-
11
-
-
2342519701
-
Genetic studies of the Lac repressor. XV: 4000 single amino acid substitutions and analysis of the resulting phenotypes on the basis of the protein structure
-
Suckow, J. et al. Genetic studies of the Lac repressor. XV: 4000 single amino acid substitutions and analysis of the resulting phenotypes on the basis of the protein structure. J. Mol. Biol. 261, 509-523 (1996).
-
(1996)
J. Mol. Biol.
, vol.261
, pp. 509-523
-
-
Suckow, J.1
-
12
-
-
0018122444
-
Genetic studies of Lac repressor V. Repressors which bind operator more tightly generated by suppression and reversion of nonsense mutations
-
Schmitz, A., Coulondre, C. & Miller, J. H. Genetic studies of Lac repressor V. Repressors which bind operator more tightly generated by suppression and reversion of nonsense mutations. J. Mol. Biol. 123, 431-454 (1978).
-
(1978)
J. Mol. Biol.
, vol.123
, pp. 431-454
-
-
Schmitz, A.1
Coulondre, C.2
Miller, J.H.3
-
13
-
-
0028076771
-
Genetic studies of the lac repressor XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence
-
Markiewicz, P., Kleina, L. G., Cruz, C., Ehret, S. & Miller, J. H. Genetic studies of the lac repressor. XIV. Analysis of 4000 altered Escherichia coli lac repressors reveals essential and non-essential residues, as well as "spacers" which do not require a specific sequence. J. Mol. Biol. 240, 421-433 (1994).
-
(1994)
J. Mol. Biol.
, vol.240
, pp. 421-433
-
-
Markiewicz, P.1
Kleina, L.G.2
Cruz, C.3
Ehret, S.4
Miller, J.H.5
-
14
-
-
0024292398
-
Missense mutation in the lacI gene of Escherichia coli. Inferences on the structure of the repressor protein
-
Gordon, A. J. et al. Missense mutation in the lacI gene of Escherichia coli. Inferences on the structure of the repressor protein. J. Mol. Biol. 200, 239-251 (1988).
-
(1988)
J. Mol. Biol.
, vol.200
, pp. 239-251
-
-
Gordon, A.J.1
-
15
-
-
0344412958
-
Perturbation from a distance: Mutations that alter LacI function through long-range effects
-
Swint-Kruse, L., Zhan, H., Fairbanks, B. M., Maheshwari, A. & Matthews, K. S. Perturbation from a distance: mutations that alter LacI function through long-range effects. Biochemistry 42, 14004-14016 (2003).
-
(2003)
Biochemistry
, vol.42
, pp. 14004-14016
-
-
Swint-Kruse, L.1
Zhan, H.2
Fairbanks, B.M.3
Maheshwari, A.4
Matthews, K.S.5
-
16
-
-
48649088787
-
Subdividing repressor function: DNA binding affinity, selectivity, and allostery can be altered by amino acid substitution of nonconserved residues in a LacI/GalR homologue
-
Zhan, H., Taraban, M., Trewhella, J. & Swint-Kruse, L. Subdividing repressor function: DNA binding affinity, selectivity, and allostery can be altered by amino acid substitution of nonconserved residues in a LacI/GalR homologue. Biochemistry 47, 8058-8069 (2008).
-
(2008)
Biochemistry
, vol.47
, pp. 8058-8069
-
-
Zhan, H.1
Taraban, M.2
Trewhella, J.3
Swint-Kruse, L.4
-
17
-
-
0034681292
-
Dimerisation mutants of Lac repressor II. A single amino acid substitution, D278L, changes the specificity of dimerisation
-
Spott, S., Dong, F., Kisters-Woike, B. & Müller-Hill, B. Dimerisation mutants of Lac repressor. II. A single amino acid substitution, D278L, changes the specificity of dimerisation. J. Mol. Biol. 296, 673-684 (2000).
-
(2000)
J. Mol. Biol.
, vol.296
, pp. 673-684
-
-
Spott, S.1
Dong, F.2
Kisters-Woike, B.3
Müller-Hill, B.4
-
18
-
-
0029004903
-
Crystal structure of lac repressor core tetramer and its implications for DNA looping
-
Friedman, A. M., Fischmann, T. O. & Steitz, T. A. Crystal structure of lac repressor core tetramer and its implications for DNA looping. Science 268, 1721-1727 (1995).
-
(1995)
Science
, vol.268
, pp. 1721-1727
-
-
Friedman, A.M.1
Fischmann, T.O.2
Steitz, T.A.3
-
19
-
-
0029938053
-
Crystal structure of the lactose operon repressor and its complexes with DNA and inducer
-
Lewis, M. et al. Crystal structure of the lactose operon repressor and its complexes with DNA and inducer. Science 271, 1247-1254 (1996).
-
(1996)
Science
, vol.271
, pp. 1247-1254
-
-
Lewis, M.1
-
20
-
-
0026723976
-
Deletion of lactose repressor carboxyl-terminal domain affects tetramer formation
-
Chen, J. & Matthews, K. S. Deletion of lactose repressor carboxyl-terminal domain affects tetramer formation. J. Biol. Chem. 267, 13843-13850 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 13843-13850
-
-
Chen, J.1
Matthews, K.S.2
-
21
-
-
34249951731
-
Structural analysis of lac repressor bound to allosteric effectors
-
Daber, R., Stayrook, S., Rosenberg, A. & Lewis, M. Structural analysis of lac repressor bound to allosteric effectors. J. Mol. Biol. 370, 609-619 (2007).
-
(2007)
J. Mol. Biol.
, vol.370
, pp. 609-619
-
-
Daber, R.1
Stayrook, S.2
Rosenberg, A.3
Lewis, M.4
-
22
-
-
0034007725
-
Relieving repression
-
Matthews, K. S., Falcon, C. M. & Swint-Kruse, L. Relieving repression. Nat. Struct. Biol. 7, 184-187 (2000).
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 184-187
-
-
Matthews, K.S.1
Falcon, C.M.2
Swint-Kruse, L.3
-
23
-
-
0034089394
-
A closer view of the conformation of the Lac repressor bound to operator
-
Bell, C. E. & Lewis, M. A closer view of the conformation of the Lac repressor bound to operator. Nat. Struct. Biol. 7, 209-214 (2000).
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 209-214
-
-
Bell, C.E.1
Lewis, M.2
-
24
-
-
0030921749
-
Lac repressor genetic map in real space
-
Pace, H. C. et al. Lac repressor genetic map in real space. Trends Biochem. Sci. 22, 334-339 (1997).
-
(1997)
Trends Biochem. Sci.
, vol.22
, pp. 334-339
-
-
Pace, H.C.1
-
25
-
-
38349193126
-
Ligand-induced conformational changes and conformational dynamics in the solution structure of the lactose repressor protein
-
Taraban, M. et al. Ligand-induced conformational changes and conformational dynamics in the solution structure of the lactose repressor protein. J. Mol. Biol. 376, 466-481 (2008).
-
(2008)
J. Mol. Biol.
, vol.376
, pp. 466-481
-
-
Taraban, M.1
-
26
-
-
66649102153
-
Flexibility in the inducer binding region is crucial for allostery in the Escherichia coli lactose repressor
-
Xu, J. & Matthews, K. S. Flexibility in the inducer binding region is crucial for allostery in the Escherichia coli lactose repressor. Biochemistry 48, 4988-4998 (2009).
-
(2009)
Biochemistry
, vol.48
, pp. 4988-4998
-
-
Xu, J.1
Matthews, K.S.2
-
27
-
-
63749116038
-
Allostery in the LacI/GalR family: Variations on a theme
-
Swint-Kruse, L. & Matthews, K. S. Allostery in the LacI/GalR family: variations on a theme. Curr. Opin. Microbiol. 12, 129-137 (2009).
-
(2009)
Curr. Opin. Microbiol.
, vol.12
, pp. 129-137
-
-
Swint-Kruse, L.1
Matthews, K.S.2
-
28
-
-
84878030130
-
Engineering alternate cooperative-communications in the lactose repressor protein scaffold
-
Meyer, S. et al. Engineering alternate cooperative-communications in the lactose repressor protein scaffold. Protein Eng. Des. Sel. 26, 433-443 (2013).
-
(2013)
Protein Eng. Des. Sel.
, vol.26
, pp. 433-443
-
-
Meyer, S.1
-
29
-
-
84916207914
-
Engineering allostery
-
Raman, S., Taylor, N., Genuth, N., Fields, S. & Church, G. M. Engineering allostery. Trends Genet. 30, 521-528 (2014).
-
(2014)
Trends Genet.
, vol.30
, pp. 521-528
-
-
Raman, S.1
Taylor, N.2
Genuth, N.3
Fields, S.4
Church, G.M.5
-
30
-
-
0032532164
-
A lactulose sensor based on coupled enzyme reactions with a ring electrode fabricated from tetrathiafulvalentetracyanoquinodimetane
-
Sekine, Y. & Hall, E. A. A lactulose sensor based on coupled enzyme reactions with a ring electrode fabricated from tetrathiafulvalentetracyanoquinodimetane. Biosens. Bioelectron. 13, 995-1005 (1998).
-
(1998)
Biosens. Bioelectron.
, vol.13
, pp. 995-1005
-
-
Sekine, Y.1
Hall, E.A.2
-
31
-
-
0343652762
-
Rapid determination of lactulose in milk by microdialysis and biosensors
-
Moscone, D., Bernardo, R. A., Marconi, E., Amine, A. & Palleschi, G. Rapid determination of lactulose in milk by microdialysis and biosensors. Analyst 124, 325-329 (1999).
-
(1999)
Analyst
, vol.124
, pp. 325-329
-
-
Moscone, D.1
Bernardo, R.A.2
Marconi, E.3
Amine, A.4
Palleschi, G.5
-
32
-
-
84655160877
-
Lactulose production from lactose as a single substrate by a thermostable cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus
-
Kim, Y. S. & Oh, D. K. Lactulose production from lactose as a single substrate by a thermostable cellobiose 2-epimerase from Caldicellulosiruptor saccharolyticus. Bioresour. Technol. 104, 668-672 (2012).
-
(2012)
Bioresour. Technol.
, vol.104
, pp. 668-672
-
-
Kim, Y.S.1
Oh, D.K.2
-
33
-
-
0016745534
-
Interaction of effecting ligands with lac repressor and repressor-operator complex
-
Barkley, M. D., Riggs, A. D., Jobe, A. & Burgeois, S. Interaction of effecting ligands with lac repressor and repressor-operator complex. Biochemistry 14, 1700-1712 (1975).
-
(1975)
Biochemistry
, vol.14
, pp. 1700-1712
-
-
Barkley, M.D.1
Riggs, A.D.2
Jobe, A.3
Burgeois, S.4
-
34
-
-
0022856787
-
An evolutionary perspective on synonymous codon usage in unicellular organisms
-
Sharp, P. M. & Li, W. H. An evolutionary perspective on synonymous codon usage in unicellular organisms. J. Mol. Evol. 24, 28-38 (1986).
-
(1986)
J. Mol. Evol.
, vol.24
, pp. 28-38
-
-
Sharp, P.M.1
Li, W.H.2
-
35
-
-
84890069561
-
Selection on codon bias in yeast: A transcriptional hypothesis
-
Trotta, E. Selection on codon bias in yeast: a transcriptional hypothesis. Nucleic Acids Res. 41, 9382-9395 (2013).
-
(2013)
Nucleic Acids Res.
, vol.41
, pp. 9382-9395
-
-
Trotta, E.1
-
36
-
-
25844513164
-
The Relationship among gene expression, folding free energy and codon usage bias in Escherichia coli
-
Jia, M. W. & Li, Y. D. The Relationship among gene expression, folding free energy and codon usage bias in Escherichia coli. FEBS Lett. 579, 5333-5337 (2005).
-
(2005)
FEBS Lett.
, vol.579
, pp. 5333-5337
-
-
Jia, M.W.1
Li, Y.D.2
-
37
-
-
0034765913
-
The relationship between third-codon position nucleotide content, codon bias, mRNA secondary structure and gene expression in the Drosophilid alcohol dehydrogenase genes Adh and Adhr
-
Carlini, D. B., Chen, Y. & Stephan, W. The relationship between third-codon position nucleotide content, codon bias, mRNA secondary structure and gene expression in the Drosophilid alcohol dehydrogenase genes Adh and Adhr. Genetics 159, 623-633 (2001).
-
(2001)
Genetics
, vol.159
, pp. 623-633
-
-
Carlini, D.B.1
Chen, Y.2
Stephan, W.3
-
38
-
-
0141519339
-
Widespread selection for local RNA secondary structure in coding regions of bacterial genes
-
Katz, L. & Burge, C. B. Widespread selection for local RNA secondary structure in coding regions of bacterial genes. Genome Res. 13, 2042-2051 (2003).
-
(2003)
Genome Res.
, vol.13
, pp. 2042-2051
-
-
Katz, L.1
Burge, C.B.2
-
39
-
-
76649107887
-
Galacto-oligosaccharide production using microbial beta-galactosidase: Current state and perspectives
-
Park, A. R. & Oh, D. K. Galacto-oligosaccharide production using microbial beta-galactosidase: current state and perspectives. Appl. Microbiol. Biot. 85, 1279-1286 (2010).
-
(2010)
Appl. Microbiol. Biot.
, vol.85
, pp. 1279-1286
-
-
Park, A.R.1
Oh, D.K.2
-
40
-
-
84879845094
-
Enzymatic production of lactulose and 1-lactulose: Current state and perspectives
-
Wang, H., Yang, R., Hua, X., Zhao, W. & Zhang, W. Enzymatic production of lactulose and 1-lactulose: current state and perspectives. Appl. Microbiol. Biot. 97, 6167-6180 (2013).
-
(2013)
Appl. Microbiol. Biot.
, vol.97
, pp. 6167-6180
-
-
Wang, H.1
Yang, R.2
Hua, X.3
Zhao, W.4
Zhang, W.5
-
41
-
-
31544450286
-
Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: The Keio collection
-
2006.0008
-
Baba, T. et al. Construction of Escherichia coli K-12 in-frame, single-gene knockout mutants: the Keio collection. Mol. Syst. Biol. 2, 2006.0008 (2006).
-
(2006)
Mol. Syst. Biol.
, vol.2
-
-
Baba, T.1
-
42
-
-
0034612342
-
One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products
-
Datsenko, K. A. & Wanner, B. L. One-step inactivation of chromosomal genes in Escherichia coli K-12 using PCR products. Proc. Natl. Acad. Sci. USA 97, 6640-6645 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 6640-6645
-
-
Datsenko, K.A.1
Wanner, B.L.2
-
43
-
-
84923862490
-
Design and application of a novel high-throughput screening technique for 1-deoxynojirimycin
-
Jiang, P. et al. Design and application of a novel high-throughput screening technique for 1-deoxynojirimycin. Sci. Rep.-UK 5, 8563 (2015).
-
(2015)
Sci. Rep.-UK
, vol.5
, pp. 8563
-
-
Jiang, P.1
-
44
-
-
1842842876
-
Creating random mutagenesis libraries using megaprimer PCR of whole plasmid
-
Miyazaki, K. & Takenouchi, M. Creating random mutagenesis libraries using megaprimer PCR of whole plasmid. Biotechniques 33, 1033-1034, 1036-1038 (2002).
-
(2002)
Biotechniques
, vol.33
, pp. 1033-1034
-
-
Miyazaki, K.1
Takenouchi, M.2
|