메뉴 건너뛰기




Volumn 24, Issue 4, 2017, Pages 588-596

'Hints' in the killer protein gasdermin D: Unveiling the secrets of gasdermins driving cell death

Author keywords

[No Author keywords available]

Indexed keywords

DFNA5; INFLAMMASOME; LIM DOMAIN ONLY 1; LIM PROTEIN; PROTEIN GASDERMIN A; PROTEIN GASDERMIN D; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR; UNCLASSIFIED DRUG; CASPASE; DFNA5 PROTEIN, HUMAN; ESTROGEN RECEPTOR; GSDMA PROTEIN, HUMAN; GSDMD PROTEIN, HUMAN; SACCHAROMYCES CEREVISIAE PROTEIN; TUMOR PROTEIN;

EID: 85016594753     PISSN: 13509047     EISSN: 14765403     Source Type: Journal    
DOI: 10.1038/cdd.2017.24     Document Type: Article
Times cited : (103)

References (58)
  • 1
    • 84927745897 scopus 로고    scopus 로고
    • Pyroptotic cell death defends against intracellular pathogens
    • Jorgensen I, Miao EA. Pyroptotic cell death defends against intracellular pathogens. Immunol Rev 2015; 265: 130-142.
    • (2015) Immunol Rev , vol.265 , pp. 130-142
    • Jorgensen, I.1    Miao, E.A.2
  • 4
    • 84883790050 scopus 로고    scopus 로고
    • Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock
    • Hagar JA, Powell DA, Aachoui Y, Ernst RK, Miao EA. Cytoplasmic LPS activates caspase-11: Implications in TLR4-independent endotoxic shock. Science 2013; 341: 1250-1253.
    • (2013) Science , vol.341 , pp. 1250-1253
    • Hagar, J.A.1    Powell, D.A.2    Aachoui, Y.3    Ernst, R.K.4    Miao, E.A.5
  • 5
    • 84906571225 scopus 로고    scopus 로고
    • Inflammatory caspases are innate immune receptors for intracellular LPS
    • Shi J, Zhao Y, Wang Y, Gao W, Ding J, Li P, et al. Inflammatory caspases are innate immune receptors for intracellular LPS. Nature 2014; 514: 187-192.
    • (2014) Nature , vol.514 , pp. 187-192
    • Shi, J.1    Zhao, Y.2    Wang, Y.3    Gao, W.4    D'Ing, J.5    Li, P.6
  • 6
    • 84976516826 scopus 로고    scopus 로고
    • Inflammasomes: Mechanism of assembly, regulation and signalling
    • Broz P, Dixit VM. Inflammasomes: Mechanism of assembly, regulation and signalling. Nat Rev Immunol 2016; 16: 407-420.
    • (2016) Nat Rev Immunol , vol.16 , pp. 407-420
    • Broz, P.1    D'Ixit, V.M.2
  • 7
    • 84942892037 scopus 로고    scopus 로고
    • Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death
    • Shi J, Zhao Y, Wang K, Shi X, Wang Y, Huang H, et al. Cleavage of GSDMD by inflammatory caspases determines pyroptotic cell death. Nature 2015; 526: 660-665.
    • (2015) Nature , vol.526 , pp. 660-665
    • Shi, J.1    Zhao, Y.2    Wang, K.3    Shi, X.4    Wang, Y.5    Huang, H.6
  • 8
    • 84942856523 scopus 로고    scopus 로고
    • Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling
    • Kayagaki N, Stowe IB, Lee BL, O'Rourke K, Anderson K, Warming S, et al. Caspase-11 cleaves gasdermin D for non-canonical inflammasome signalling. Nature 2015; 526: 666-671.
    • (2015) Nature , vol.526 , pp. 666-671
    • Kayagaki, N.1    Stowe, I.B.2    Lee, B.L.3    O'Rourke, K.4    Anderson, K.5    Warming, S.6
  • 9
    • 84978419608 scopus 로고    scopus 로고
    • Pore-forming activity and structural autoinhibition of the gasdermin family
    • Ding J, Wang K, Liu W, She Y, Sun Q, Shi J, et al. Pore-forming activity and structural autoinhibition of the gasdermin family. Nature 2016; 535: 111-116.
    • (2016) Nature , vol.535 , pp. 111-116
    • D'Ing, J.1    Wang, K.2    Liu, W.3    She, Y.4    Sun, Q.5    Shi, J.6
  • 10
    • 84934938651 scopus 로고    scopus 로고
    • Loss of conserved Gsdma3 self-regulation causes autophagy and cell death
    • Shi P, Tang A, Xian L, Hou S, Zou D, Lv Y, et al. Loss of conserved Gsdma3 self-regulation causes autophagy and cell death. Biochem J 2015; 468: 325-336.
    • (2015) Biochem J , vol.468 , pp. 325-336
    • Shi, P.1    Tang, A.2    Xian, L.3    Hou, S.4    Zou, D.5    Lv, Y.6
  • 11
    • 34247217928 scopus 로고    scopus 로고
    • Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner
    • Tamura M, Tanaka S, Fujii T, Aoki A, Komiyama H, Ezawa K, et al. Members of a novel gene family, Gsdm, are expressed exclusively in the epithelium of the skin and gastrointestinal tract in a highly tissue-specific manner. Genomics 2007; 89: 618-629.
    • (2007) Genomics , vol.89 , pp. 618-629
    • Tamura, M.1    Tanaka, S.2    Fujii, T.3    Aoki, A.4    Komiyama, H.5    Ezawa, K.6
  • 12
    • 84960931781 scopus 로고    scopus 로고
    • Association between gasdermin A and gasdermin B polymorphisms and susceptibility to adult and childhood asthma among Jordanians
    • Zihlif M, Obeidat NM, Zihlif N, Mahafza T, Froukh T, Ghanim MT, et al. Association between gasdermin A and gasdermin B polymorphisms and susceptibility to adult and childhood asthma among Jordanians. Genet Test Mol Biomarkers 2016; 20: 143-148.
    • (2016) Genet Test Mol Biomarkers , vol.20 , pp. 143-148
    • Zihlif, M.1    Obeidat, N.M.2    Zihlif, N.3    Mahafza, T.4    Froukh, T.5    Ghanim, M.T.6
  • 13
    • 84922444776 scopus 로고    scopus 로고
    • Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus
    • Acevedo N, Reinius LE, Greco D, Gref A, Orsmark-Pietras C, Persson H, et al. Risk of childhood asthma is associated with CpG-site polymorphisms, regional DNA methylation and mRNA levels at the GSDMB/ORMDL3 locus. Hum Mol Genet 2015; 24: 875-890.
    • (2015) Hum Mol Genet , vol.24 , pp. 875-890
    • Acevedo, N.1    Reinius, L.E.2    Greco, D.3    Gref, A.4    Orsmark-Pietras, C.5    Persson, H.6
  • 14
    • 79959815406 scopus 로고    scopus 로고
    • Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR
    • Yu J, Kang MJ, Kim BJ, Kwon JW, Song YH, Choi WA, et al. Polymorphisms in GSDMA and GSDMB are associated with asthma susceptibility, atopy and BHR. Pediatr Pulmonol 2011; 46: 701-708.
    • (2011) Pediatr Pulmonol , vol.46 , pp. 701-708
    • Yu, J.1    Kang, M.J.2    Kim, B.J.3    Kwon, J.W.4    Song, Y.H.5    Choi, W.A.6
  • 15
    • 79957835071 scopus 로고    scopus 로고
    • Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion
    • Lluis A, Schedel M, Liu J, Illi S, Depner M, von Mutius E, et al. Asthma-associated polymorphisms in 17q21 influence cord blood ORMDL3 and GSDMA gene expression and IL-17 secretion. J Allergy Clin Immunol 2011; 127: 1587-1594 e6.
    • (2011) J Allergy Clin Immunol , vol.127 , pp. 1587-1594e6
    • Lluis, A.1    Schedel, M.2    Liu, J.3    Illi, S.4    Depner, M.5    Von Mutius, E.6
  • 16
    • 77952787002 scopus 로고    scopus 로고
    • Alu-derived cis-element regulates tumorigenesis-dependent gastric expression of GASDERMIN B (GSDMB)
    • Komiyama H, Aoki A, Tanaka S, Maekawa H, Kato Y, Wada R, et al. Alu-derived cis-element regulates tumorigenesis-dependent gastric expression of GASDERMIN B (GSDMB). Genes Genet Syst 2010; 85: 75-83.
    • (2010) Genes Genet Syst , vol.85 , pp. 75-83
    • Komiyama, H.1    Aoki, A.2    Tanaka, S.3    Maekawa, H.4    Kato, Y.5    Wada, R.6
  • 17
    • 62449133719 scopus 로고    scopus 로고
    • Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium
    • Saeki N, Usui T, Aoyagi K, Kim DH, Sato M, Mabuchi T, et al. Distinctive expression and function of four GSDM family genes (GSDMA-D) in normal and malignant upper gastrointestinal epithelium. Genes Chromosomes Cancer 2009; 48: 261-271.
    • (2009) Genes Chromosomes Cancer , vol.48 , pp. 261-271
    • Saeki, N.1    Usui, T.2    Aoyagi, K.3    Kim, D.H.4    Sato, M.5    Mabuchi, T.6
  • 18
    • 34948833165 scopus 로고    scopus 로고
    • GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling
    • Saeki N, Kim DH, Usui T, Aoyagi K, Tatsuta T, Aoki K, et al. GASDERMIN, suppressed frequently in gastric cancer, is a target of LMO1 in TGF-beta-dependent apoptotic signalling. Oncogene 2007; 26: 6488-6498.
    • (2007) Oncogene , vol.26 , pp. 6488-6498
    • Saeki, N.1    Kim, D.H.2    Usui, T.3    Aoyagi, K.4    Tatsuta, T.5    Aoki, K.6
  • 19
    • 84949091051 scopus 로고    scopus 로고
    • Gasdermin D is an executor of pyroptosis and required for interleukin-1beta secretion
    • He WT, Wan H, Hu L, Chen P, Wang X, Huang Z, et al. Gasdermin D is an executor of pyroptosis and required for interleukin-1beta secretion. Cell Res 2015; 25: 1285-1298.
    • (2015) Cell Res , vol.25 , pp. 1285-1298
    • He, W.T.1    Wan, H.2    Hu, L.3    Chen, P.4    Wang, X.5    Huang, Z.6
  • 20
    • 84984822442 scopus 로고    scopus 로고
    • Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis
    • Chen X, He WT, Hu L, Li J, Fang Y, Wang X, et al. Pyroptosis is driven by non-selective gasdermin-D pore and its morphology is different from MLKL channel-mediated necroptosis. Cell Res 2016; 26: 1007-1020.
    • (2016) Cell Res , vol.26 , pp. 1007-1020
    • Chen, X.1    He, W.T.2    Hu, L.3    Li, J.4    Fang, Y.5    Wang, X.6
  • 22
    • 84982102736 scopus 로고    scopus 로고
    • GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death
    • Sborgi L, Ruhl S, Mulvihill E. GSDMD membrane pore formation constitutes the mechanism of pyroptotic cell death. EMBO J 2016; 35: 1766-1778.
    • (2016) EMBO J , vol.35 , pp. 1766-1778
    • Sborgi, L.1    Ruhl, S.2    Mulvihill, E.3
  • 23
    • 84983776563 scopus 로고    scopus 로고
    • Active caspase-1 induces plasma membrane pores that precede pyroptotic lysis and are blocked by lanthanides
    • Russo HM, Rathkey J, Boyd-Tressler A. Active caspase-1 induces plasma membrane pores that precede pyroptotic lysis and are blocked by lanthanides. J Immunol 2016; 197: 1353-1367.
    • (2016) J Immunol , vol.197 , pp. 1353-1367
    • Russo, H.M.1    Rathkey, J.2    Boyd-Tressler, A.3
  • 24
    • 84978374487 scopus 로고    scopus 로고
    • Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores
    • Liu X, Zhang Z, Ruan J, Pan Y, Magupalli VG, Wu H, et al. Inflammasome-activated gasdermin D causes pyroptosis by forming membrane pores. Nature 2016; 535: 153-158.
    • (2016) Nature , vol.535 , pp. 153-158
    • Liu, X.1    Zhang, Z.2    Ruan, J.3    Pan, Y.4    Magupalli, V.G.5    Wu, H.6
  • 25
    • 84922565465 scopus 로고    scopus 로고
    • Host defense peptides: Front-line immunomodulators
    • Mansour SC, Pena OM, Hancock RE. Host defense peptides: Front-line immunomodulators. Trends Immunol 2014; 35: 443-450.
    • (2014) Trends Immunol , vol.35 , pp. 443-450
    • Mansour, S.C.1    Pena, O.M.2    Hancock, R.E.3
  • 26
    • 26844567701 scopus 로고    scopus 로고
    • Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli
    • Chen X, Niyonsaba F, Ushio H, Okuda D, Nagaoka I, Ikeda S, et al. Synergistic effect of antibacterial agents human beta-defensins, cathelicidin LL-37 and lysozyme against Staphylococcus aureus and Escherichia coli. J Dermatol Sci 2005; 40: 123-132.
    • (2005) J Dermatol Sci , vol.40 , pp. 123-132
    • Chen, X.1    Niyonsaba, F.2    Ushio, H.3    Okuda, D.4    Nagaoka, I.5    Ikeda, S.6
  • 28
    • 84867330849 scopus 로고    scopus 로고
    • Gsdma3 is a new factor needed for TNF-alpha-mediated apoptosis signal pathway in mouse skin keratinocytes
    • Lei M, Bai X, Yang T, Lai X, Qiu W, Yang L, et al. Gsdma3 is a new factor needed for TNF-alpha-mediated apoptosis signal pathway in mouse skin keratinocytes. Histochem Cell Biol 2012; 138: 385-396.
    • (2012) Histochem Cell Biol , vol.138 , pp. 385-396
    • Lei, M.1    Bai, X.2    Yang, T.3    Lai, X.4    Qiu, W.5    Yang, L.6
  • 29
    • 80052462144 scopus 로고    scopus 로고
    • Gsdma3 gene is needed for the induction of apoptosis-driven catagen during mouse hair follicle cycle
    • Lei M, Gao X, Yang L, Yang T, Lian X. Gsdma3 gene is needed for the induction of apoptosis-driven catagen during mouse hair follicle cycle. Histochem Cell Biol 2011; 136: 335-343.
    • (2011) Histochem Cell Biol , vol.136 , pp. 335-343
    • Lei, M.1    Gao, X.2    Yang, L.3    Yang, T.4    Lian, X.5
  • 30
    • 84935031669 scopus 로고    scopus 로고
    • N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting
    • Lin PH, Lin HY, Kuo CC, Yang LT. N-terminal functional domain of Gasdermin A3 regulates mitochondrial homeostasis via mitochondrial targeting. J Biomed Sci 2015; 22: 44.
    • (2015) J Biomed Sci , vol.22 , pp. 44
    • Lin, P.H.1    Lin, H.Y.2    Kuo, C.C.3    Yang, L.T.4
  • 32
    • 84885813096 scopus 로고    scopus 로고
    • Functional conservation of Gsdma cluster genes specifically duplicated in the mouse genome
    • Tanaka S, Mizushina Y, Kato Y, Tamura M, Shiroishi T. Functional conservation of Gsdma cluster genes specifically duplicated in the mouse genome. G3 2013; 3: 1843-1850.
    • (2013) G3 , vol.3 , pp. 1843-1850
    • Tanaka, S.1    Mizushina, Y.2    Kato, Y.3    Tamura, M.4    Shiroishi, T.5
  • 33
    • 84922776083 scopus 로고    scopus 로고
    • PINK1/Parkin-mediated mitophagy in mammalian cells
    • Eiyama A, Okamoto K. PINK1/Parkin-mediated mitophagy in mammalian cells. Curr Opin Cell Biol 2015; 33: 95-101.
    • (2015) Curr Opin Cell Biol , vol.33 , pp. 95-101
    • Eiyama, A.1    Okamoto, K.2
  • 35
    • 84874640848 scopus 로고    scopus 로고
    • Tom70 is essential for PINK1 import into mitochondria
    • Kato H, Lu Q, Rapaport D, Kozjak-Pavlovic V. Tom70 is essential for PINK1 import into mitochondria. PLoS ONE 2013; 8: E58435.
    • (2013) PLoS ONE , vol.8 , pp. E58435
    • Kato, H.1    Lu, Q.2    Rapaport, D.3    Kozjak-Pavlovic, V.4
  • 37
    • 84904039455 scopus 로고    scopus 로고
    • A novel splice site mutation in DFNA5 causes late-onset progressive non-syndromic hearing loss in a Chinese family
    • Chai Y, Chen D, Wang X, Wu H, Yang T. A novel splice site mutation in DFNA5 causes late-onset progressive non-syndromic hearing loss in a Chinese family. Int J Pediatr Otorhinolaryngol 2014; 78: 1265-1268.
    • (2014) Int J Pediatr Otorhinolaryngol , vol.78 , pp. 1265-1268
    • Chai, Y.1    Chen, D.2    Wang, X.3    Wu, H.4    Yang, T.5
  • 40
    • 0141957280 scopus 로고    scopus 로고
    • A 3-nucleotide deletion in the polypyrimidine tract of intron 7 of the DFNA5 gene causes nonsyndromic hearing impairment in a Chinese family
    • Yu C, Meng X, Zhang S, Zhao G, Hu L, Kong X. A 3-nucleotide deletion in the polypyrimidine tract of intron 7 of the DFNA5 gene causes nonsyndromic hearing impairment in a Chinese family. Genomics 2003; 82: 575-579.
    • (2003) Genomics , vol.82 , pp. 575-579
    • Yu, C.1    Meng, X.2    Zhang, S.3    Zhao, G.4    Hu, L.5    Kong, X.6
  • 41
    • 35348897928 scopus 로고    scopus 로고
    • A novel DFNA5 mutation, IVS8 +4A4G, in the splice donor site of intron 8 causes late-onset non-syndromic hearing loss in a Chinese family
    • Cheng J, Han DY, Dai P, Sun HJ, Tao R, Sun Q, et al. A novel DFNA5 mutation, IVS8 +4A4G, in the splice donor site of intron 8 causes late-onset non-syndromic hearing loss in a Chinese family. Clin Genet 2007; 72: 471-477.
    • (2007) Clin Genet , vol.72 , pp. 471-477
    • Cheng, J.1    Han, D.Y.2    Dai, P.3    Sun, H.J.4    Tao, R.5    Sun, Q.6
  • 42
    • 33751351899 scopus 로고    scopus 로고
    • Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer
    • Akino K, Toyota M, Suzuki H, Imai T, Maruyama R, Kusano M, et al. Identification of DFNA5 as a target of epigenetic inactivation in gastric cancer. Cancer Sci 2007; 98: 88-95.
    • (2007) Cancer Sci , vol.98 , pp. 88-95
    • Akino, K.1    Toyota, M.2    Suzuki, H.3    Imai, T.4    Maruyama, R.5    Kusano, M.6
  • 43
    • 44849133161 scopus 로고    scopus 로고
    • Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma
    • Kim MS, Chang X, Yamashita K, Nagpal JK, Baek JH, Wu G, et al. Aberrant promoter methylation and tumor suppressive activity of the DFNA5 gene in colorectal carcinoma. Oncogene 2008; 27: 3624-3634.
    • (2008) Oncogene , vol.27 , pp. 3624-3634
    • Kim, M.S.1    Chang, X.2    Yamashita, K.3    Nagpal, J.K.4    Baek, J.H.5    Wu, G.6
  • 45
    • 84890425483 scopus 로고    scopus 로고
    • The expression and regulation of DFNA5 in human hepatocellular carcinoma DFNA5 in hepatocellular carcinoma
    • Wang CJ, Tang L, Shen DW, Wang C, Yuan QY, Gao W, et al. The expression and regulation of DFNA5 in human hepatocellular carcinoma DFNA5 in hepatocellular carcinoma. Mol Biol Rep 2013; 40: 6525-6531.
    • (2013) Mol Biol Rep , vol.40 , pp. 6525-6531
    • Wang, C.J.1    Tang, L.2    Shen, D.W.3    Wang, C.4    Yuan, Q.Y.5    Gao, W.6
  • 46
    • 0035815465 scopus 로고    scopus 로고
    • DFNA5 (ICERE-1) contributes to acquired etoposide resistance in melanoma cells
    • Lage H, Helmbach H, Grottke C, Dietel M, Schadendorf D. DFNA5 (ICERE-1) contributes to acquired etoposide resistance in melanoma cells. FEBS Lett 2001; 494: 54-59.
    • (2001) FEBS Lett , vol.494 , pp. 54-59
    • Lage, H.1    Helmbach, H.2    Grottke, C.3    D'Ietel, M.4    Schadendorf, D.5
  • 47
    • 77952881777 scopus 로고    scopus 로고
    • The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage
    • Masuda Y, Futamura M, Kamino H, Nakamura Y, Kitamura N, Ohnishi S, et al. The potential role of DFNA5, a hearing impairment gene, in p53-mediated cellular response to DNA damage. J Hum Genet 2006; 51: 652-664.
    • (2006) J Hum Genet , vol.51 , pp. 652-664
    • Masuda, Y.1    Futamura, M.2    Kamino, H.3    Nakamura, Y.4    Kitamura, N.5    Ohnishi, S.6
  • 48
    • 0037630746 scopus 로고    scopus 로고
    • A yeast model for the study of human DFNA5, a gene mutated in nonsyndromic hearing impairment
    • Gregan J, Van Laer L, Lieto LD, Van Camp G, Kearsey SE. A yeast model for the study of human DFNA5, a gene mutated in nonsyndromic hearing impairment. Biochim Biophys Acta 2003; 1638: 179-186.
    • (2003) Biochim Biophys Acta , vol.1638 , pp. 179-186
    • Gregan, J.1    Van Laer, L.2    Lieto, L.D.3    Van Camp, G.4    Kearsey, S.E.5
  • 50
    • 80052032972 scopus 로고    scopus 로고
    • The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein
    • Op de Beeck K, Van Camp G, Thys S, Cools N, Callebaut I, Vrijens K, et al. The DFNA5 gene, responsible for hearing loss and involved in cancer, encodes a novel apoptosis-inducing protein. Eur J Hum Genet 2011; 19: 965-973.
    • (2011) Eur J Hum Genet , vol.19 , pp. 965-973
    • Op De Beeck, K.1    Van Camp, G.2    Thys, S.3    Cools, N.4    Callebaut, I.5    Vrijens, K.6
  • 51
    • 84891095148 scopus 로고    scopus 로고
    • The splicing mutant of the human tumor suppressor protein DFNA5 induces programmed cell death when expressed in the yeast Saccharomyces cerevisiae
    • Van Rossom S, Op de Beeck K, Franssens V, Swinnen E, Schepers A, Ghillebert R, et al. The splicing mutant of the human tumor suppressor protein DFNA5 induces programmed cell death when expressed in the yeast Saccharomyces cerevisiae. Front Oncol 2012; 2: 77.
    • (2012) Front Oncol , vol.2 , pp. 77
    • Van Rossom, S.1    Op De Beeck, K.2    Franssens, V.3    Swinnen, E.4    Schepers, A.5    Ghillebert, R.6
  • 53
    • 85008419254 scopus 로고    scopus 로고
    • Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death
    • Rogers C, Fernandes-Alnemri T, Mayes L, Alnemri D, Cingolani G, Alnemri ES. Cleavage of DFNA5 by caspase-3 during apoptosis mediates progression to secondary necrotic/pyroptotic cell death. Nat Commun 2017; 8: 14128.
    • (2017) Nat Commun , vol.8 , pp. 14128
    • Rogers, C.1    Fernandes-Alnemri, T.2    Mayes, L.3    Alnemri, D.4    Cingolani, G.5    Alnemri, E.S.6
  • 54
    • 78249253033 scopus 로고    scopus 로고
    • Secondary necrosis: The natural outcome of the complete apoptotic program
    • Silva MT. Secondary necrosis: The natural outcome of the complete apoptotic program. FEBS Lett 2010; 584: 4491-4499.
    • (2010) FEBS Lett , vol.584 , pp. 4491-4499
    • Silva, M.T.1
  • 55
    • 41149115987 scopus 로고    scopus 로고
    • Secondary necrosis in multicellular animals: An outcome of apoptosis with pathogenic implications
    • Silva MT, do Vale A, dos Santos NM. Secondary necrosis in multicellular animals: An outcome of apoptosis with pathogenic implications. Apoptosis 2008; 13: 463-482.
    • (2008) Apoptosis , vol.13 , pp. 463-482
    • Silva, M.T.1    Do Vale, A.2    Dos Santos, N.M.3
  • 58
    • 33749576792 scopus 로고    scopus 로고
    • Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages
    • Fink SL, Cookson BT. Caspase-1-dependent pore formation during pyroptosis leads to osmotic lysis of infected host macrophages. Cell Microbiol 2006; 8: 1812-1825.
    • (2006) Cell Microbiol , vol.8 , pp. 1812-1825
    • Fink, S.L.1    Cookson, B.T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.