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Volumn 80, Issue , 2017, Pages 170-178

Hypothalamic-pituitary-adrenal axis genetic variation and early stress moderates amygdala function

Author keywords

Amygdala; Anxiety; Cortisol; Depression; Early life stress; Gene; HPA

Indexed keywords

ADULT; AMYGDALA; ANXIETY DISORDER; AROUSAL; ARTICLE; BIOLOGICALLY INFORMED MULTILOCUS PROFILE SCORE; BOLD SIGNAL; CHILDHOOD TRAUMA QUESTIONNAIRE; CONTROLLED STUDY; CRHR1 GENE; DEPRESSION; EARLY LIFE STRESS; EMOTION; EUROPEAN AMERICAN; FEMALE; FKBP5 GENE; FUNCTIONAL MAGNETIC RESONANCE IMAGING; GENE; GENETIC PROCEDURES; GENETIC VARIATION; HUMAN; HYPOTHALAMUS HYPOPHYSIS ADRENAL SYSTEM; INFORMED CONSENT; MALE; NR3C2 GENE; RISK FACTOR; SELF REPORT; SINGLE NUCLEOTIDE POLYMORPHISM; TASK PERFORMANCE; ADOLESCENT; ANXIETY; GENETICS; HYPOPHYSIS ADRENAL SYSTEM; HYPOTHALAMUS HYPOPHYSIS SYSTEM; LIFE EVENT; MENTAL STRESS; METABOLISM; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PHYSIOLOGY; PROCEDURES; QUESTIONNAIRE; YOUNG ADULT;

EID: 85016283658     PISSN: 03064530     EISSN: 18733360     Source Type: Journal    
DOI: 10.1016/j.psyneuen.2017.03.016     Document Type: Article
Times cited : (53)

References (75)
  • 1
    • 84928418020 scopus 로고    scopus 로고
    • Feature-based representations of emotional facial expressions in the human amygdala
    • Ahs, F., Davis, C.F., Gorka, A.X., Hariri, A.R., Feature-based representations of emotional facial expressions in the human amygdala. Soc. Cogn. Affect. Neurosci. 9 (2013), 1372–1378.
    • (2013) Soc. Cogn. Affect. Neurosci. , vol.9 , pp. 1372-1378
    • Ahs, F.1    Davis, C.F.2    Gorka, A.X.3    Hariri, A.R.4
  • 3
    • 84961990465 scopus 로고    scopus 로고
    • PER1 rs3027172 genotype interacts with early life stress to predict problematic alcohol use, but not reward-Related ventral striatum activity
    • Baranger, D.A., Ifrah, C., Prather, A.A., Carey, C.E., Corral-Frias, N.S., Drabant Conley, E., Hariri, A.R., Bogdan, R., PER1 rs3027172 genotype interacts with early life stress to predict problematic alcohol use, but not reward-Related ventral striatum activity. Front. Psychol., 7, 2016, 464.
    • (2016) Front. Psychol. , vol.7 , pp. 464
    • Baranger, D.A.1    Ifrah, C.2    Prather, A.A.3    Carey, C.E.4    Corral-Frias, N.S.5    Drabant Conley, E.6    Hariri, A.R.7    Bogdan, R.8
  • 5
    • 85016244082 scopus 로고
    • Controlling the false discovery rate: a practical and powerful approach to multiple testing
    • Benjamini, Y., Hochberg, Y., Controlling the false discovery rate: a practical and powerful approach to multiple testing. J. R. Statist. Soc. 57 (1995), 289–300.
    • (1995) J. R. Statist. Soc. , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2
  • 9
    • 70350731477 scopus 로고    scopus 로고
    • The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders
    • Binder, E.B., The role of FKBP5, a co-chaperone of the glucocorticoid receptor in the pathogenesis and therapy of affective and anxiety disorders. Psychoneuroendocrinology 34:Suppl. 1 (2009), S186–195.
    • (2009) Psychoneuroendocrinology , vol.34 , pp. S186-195
    • Binder, E.B.1
  • 10
    • 84884211352 scopus 로고    scopus 로고
    • A neurogenetics approach to understanding individual differences in brain, behavior, and risk for psychopathology
    • Bogdan, R., Hyde, L.W., Hariri, A.R., A neurogenetics approach to understanding individual differences in brain, behavior, and risk for psychopathology. Mol. Psychiatry 18 (2013), 288–299.
    • (2013) Mol. Psychiatry , vol.18 , pp. 288-299
    • Bogdan, R.1    Hyde, L.W.2    Hariri, A.R.3
  • 14
    • 0035137947 scopus 로고    scopus 로고
    • The amygdala: vigilance and emotion
    • Davis, M., Whalen, P.J., The amygdala: vigilance and emotion. Mol. Psychiatry 6 (2001), 13–34.
    • (2001) Mol. Psychiatry , vol.6 , pp. 13-34
    • Davis, M.1    Whalen, P.J.2
  • 15
    • 43049116818 scopus 로고    scopus 로고
    • Corticosteroid receptor-gene variants: modulators of the stress-response and implications for mental health
    • Derijk, R.H., van Leeuwen, N., Klok, M.D., Zitman, F.G., Corticosteroid receptor-gene variants: modulators of the stress-response and implications for mental health. Eur. J. Pharmacol. 585 (2008), 492–501.
    • (2008) Eur. J. Pharmacol. , vol.585 , pp. 492-501
    • Derijk, R.H.1    van Leeuwen, N.2    Klok, M.D.3    Zitman, F.G.4
  • 18
    • 80054953022 scopus 로고    scopus 로고
    • Influence of early life stress on later hypothalamic–pituitary–adrenal axis functioning and its covariation with mental health symptoms: a study of the allostatic process from childhood into adolescence
    • Essex, M.J., Shirtcliff, E.A., Burk, L.R., Ruttle, P.L., Klein, M.H., Slattery, M.J., Kalin, N.H., Armstrong, J.M., Influence of early life stress on later hypothalamic–pituitary–adrenal axis functioning and its covariation with mental health symptoms: a study of the allostatic process from childhood into adolescence. Dev. Psychopathol. 23 (2011), 1039–1058.
    • (2011) Dev. Psychopathol. , vol.23 , pp. 1039-1058
    • Essex, M.J.1    Shirtcliff, E.A.2    Burk, L.R.3    Ruttle, P.L.4    Klein, M.H.5    Slattery, M.J.6    Kalin, N.H.7    Armstrong, J.M.8
  • 19
    • 10344259090 scopus 로고    scopus 로고
    • The heritability of hypothalamus pituitary adrenal axis responses to psychosocial stress is context dependent
    • Federenko, I.S., Nagamine, M., Hellhamme, D.H., Wadhwa, P.D., Wust, S., The heritability of hypothalamus pituitary adrenal axis responses to psychosocial stress is context dependent. J. Clin. Endocrinol. Metab. 89 (2004), 6244–6250.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 6244-6250
    • Federenko, I.S.1    Nagamine, M.2    Hellhamme, D.H.3    Wadhwa, P.D.4    Wust, S.5
  • 20
    • 0003575875 scopus 로고    scopus 로고
    • Tructured Clinical Interview for DSM-IV Axis II Personality Disorders, (SCID-II)
    • First, M.B., Gibbon, M., Spitzer, R.L., Williams, J.B.W., Benjamin, L.S., Tructured Clinical Interview for DSM-IV Axis II Personality Disorders, (SCID-II). S, 1997.
    • (1997)
    • First, M.B.1    Gibbon, M.2    Spitzer, R.L.3    Williams, J.B.W.4    Benjamin, L.S.5
  • 23
    • 84898974748 scopus 로고    scopus 로고
    • Holm-Bonferroni Sequential Correction: An EXCEL Calculator
    • Gaetano, J., Holm-Bonferroni Sequential Correction: An EXCEL Calculator. 2013 https://www.researchgate.net/publication/236969037_Holm-Bonferroni_Sequential_Correction_An_EXCEL_Calculator.
    • (2013)
    • Gaetano, J.1
  • 24
    • 84855885330 scopus 로고    scopus 로고
    • Unconscious processing of emotions and the right hemisphere
    • Gainotti, G., Unconscious processing of emotions and the right hemisphere. Neuropsychologia 50 (2012), 205–218.
    • (2012) Neuropsychologia , vol.50 , pp. 205-218
    • Gainotti, G.1
  • 26
    • 84899985461 scopus 로고    scopus 로고
    • Multiple hypothesis testing in genomics
    • Goeman, J.J., Solari, A., Multiple hypothesis testing in genomics. Stat. Med. 33 (2014), 1946–1978.
    • (2014) Stat. Med. , vol.33 , pp. 1946-1978
    • Goeman, J.J.1    Solari, A.2
  • 27
    • 41449090413 scopus 로고    scopus 로고
    • HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression
    • Gotlib, I.H., Joormann, J., Minor, K.L., Hallmayer, J., HPA axis reactivity: a mechanism underlying the associations among 5-HTTLPR, stress, and depression. Biol. Psychiatry 63 (2008), 847–851.
    • (2008) Biol. Psychiatry , vol.63 , pp. 847-851
    • Gotlib, I.H.1    Joormann, J.2    Minor, K.L.3    Hallmayer, J.4
  • 30
    • 84942446711 scopus 로고    scopus 로고
    • Finding translation in stress research
    • Hariri, A.R., Holmes, A., Finding translation in stress research. Nat. Neurosci. 18 (2015), 1347–1352.
    • (2015) Nat. Neurosci. , vol.18 , pp. 1347-1352
    • Hariri, A.R.1    Holmes, A.2
  • 31
    • 84930899019 scopus 로고    scopus 로고
    • Looking Inside the Disordered Brain: an Introduction to the Functional Neuroanatomy of Psychopathology
    • Hariri, A.R., Looking Inside the Disordered Brain: an Introduction to the Functional Neuroanatomy of Psychopathology. 2015.
    • (2015)
    • Hariri, A.R.1
  • 32
    • 84870854437 scopus 로고    scopus 로고
    • Introduction to Mediation, Moderation and Conditional Process Analysis: A Regression-Based Approach
    • Hayes, A.F., Introduction to Mediation, Moderation and Conditional Process Analysis: A Regression-Based Approach. 2013.
    • (2013)
    • Hayes, A.F.1
  • 33
    • 84856181467 scopus 로고    scopus 로고
    • Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics
    • Heim, C., Binder, E.B., Current research trends in early life stress and depression: review of human studies on sensitive periods, gene-environment interactions, and epigenetics. Exp. Neurol. 233 (2012), 102–111.
    • (2012) Exp. Neurol. , vol.233 , pp. 102-111
    • Heim, C.1    Binder, E.B.2
  • 35
    • 77957194325 scopus 로고    scopus 로고
    • Time-dependent effects of corticosteroids on human amygdala processing
    • Henckens, M.J., van Wingen, G.A., Joels, M., Fernandez, G., Time-dependent effects of corticosteroids on human amygdala processing. J. Neurosci. 30 (2010), 12725–12732.
    • (2010) J. Neurosci. , vol.30 , pp. 12725-12732
    • Henckens, M.J.1    van Wingen, G.A.2    Joels, M.3    Fernandez, G.4
  • 39
    • 84889584152 scopus 로고    scopus 로고
    • Gene x environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution
    • Keller, M.C., Gene x environment interaction studies have not properly controlled for potential confounders: the problem and the (simple) solution. Biol. Psychiatry 75 (2014), 18–24.
    • (2014) Biol. Psychiatry , vol.75 , pp. 18-24
    • Keller, M.C.1
  • 43
    • 70149101782 scopus 로고    scopus 로고
    • Defining brain region-specific glucocorticoid action during stress by conditional gene disruption in mice
    • Kolber, B.J., Muglia, L.J., Defining brain region-specific glucocorticoid action during stress by conditional gene disruption in mice. Brain Res. 1293 (2009), 85–90.
    • (2009) Brain Res. , vol.1293 , pp. 85-90
    • Kolber, B.J.1    Muglia, L.J.2
  • 44
    • 34748856162 scopus 로고    scopus 로고
    • Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses to psychosocial stress
    • Kumsta, R., Entringer, S., Koper, J.W., van Rossum, E.F.C., Hellhammer, D.H., Wüst, S., Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses to psychosocial stress. Biol. Psychiatry 62 (2007), 863–869.
    • (2007) Biol. Psychiatry , vol.62 , pp. 863-869
    • Kumsta, R.1    Entringer, S.2    Koper, J.W.3    van Rossum, E.F.C.4    Hellhammer, D.H.5    Wüst, S.6
  • 45
    • 67349157695 scopus 로고    scopus 로고
    • Effects of stress throughout the lifespan on the brain, behaviour and cognition
    • Lupien, S.J., McEwen, B.S., Gunnar, M.R., Heim, C., Effects of stress throughout the lifespan on the brain, behaviour and cognition. Nat. Rev. Neurosci. 10 (2009), 434–445.
    • (2009) Nat. Rev. Neurosci. , vol.10 , pp. 434-445
    • Lupien, S.J.1    McEwen, B.S.2    Gunnar, M.R.3    Heim, C.4
  • 46
    • 84879327418 scopus 로고    scopus 로고
    • Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults
    • Mahon, P.B., Zandi, P.P., Potash, J.B., Nestadt, G., Wand, G.S., Genetic association of FKBP5 and CRHR1 with cortisol response to acute psychosocial stress in healthy adults. Psychopharmacology (Berl) 227 (2013), 231–241.
    • (2013) Psychopharmacology (Berl) , vol.227 , pp. 231-241
    • Mahon, P.B.1    Zandi, P.P.2    Potash, J.B.3    Nestadt, G.4    Wand, G.S.5
  • 47
    • 4744347232 scopus 로고    scopus 로고
    • Responsiveness of the hypothalamic-pituitary-adrenal axis to different novel environments is a consistent individual trait in adult male outbred rats
    • Marquez, C., Nadal, R., Armario, A., Responsiveness of the hypothalamic-pituitary-adrenal axis to different novel environments is a consistent individual trait in adult male outbred rats. Psychoneuroendocrinology 30 (2005), 179–187.
    • (2005) Psychoneuroendocrinology , vol.30 , pp. 179-187
    • Marquez, C.1    Nadal, R.2    Armario, A.3
  • 48
    • 84860298178 scopus 로고    scopus 로고
    • The impact of childhood maltreatment: a review of neurobiological and genetic factors
    • Mccrory, E., Brito, S.A.D., Viding, E., The impact of childhood maltreatment: a review of neurobiological and genetic factors. Front Psychiatry 2 (2011), 1–14.
    • (2011) Front Psychiatry , vol.2 , pp. 1-14
    • Mccrory, E.1    Brito, S.A.D.2    Viding, E.3
  • 50
    • 79960309639 scopus 로고    scopus 로고
    • Multilocus genetic profile for dopamine signaling predicts ventral striatum reactivity
    • Nikolova, Y.S., Ferrell, R.E., Manuck, S.B., Hariri, A.R., Multilocus genetic profile for dopamine signaling predicts ventral striatum reactivity. Neuropsychopharmacology 36 (2011), 1940–1947.
    • (2011) Neuropsychopharmacology , vol.36 , pp. 1940-1947
    • Nikolova, Y.S.1    Ferrell, R.E.2    Manuck, S.B.3    Hariri, A.R.4
  • 53
    • 33746512512 scopus 로고    scopus 로고
    • Principal components analysis corrects for stratification in genome-wide association studies
    • Price, A., Patterson, N., Plenge, R., Weinblatt, M., Shadick, N., Reich, D., Principal components analysis corrects for stratification in genome-wide association studies. Nat. Genet. 2:38 (2006), 904–909.
    • (2006) Nat. Genet. , vol.2 , Issue.38 , pp. 904-909
    • Price, A.1    Patterson, N.2    Plenge, R.3    Weinblatt, M.4    Shadick, N.5    Reich, D.6
  • 54
    • 35148878047 scopus 로고    scopus 로고
    • Dissociative symptoms in alcohol-dependent patients: associations with childhood trauma and substance abuse characteristics
    • Schäfer, I., Reininghaus, U., Langeland, W., Voss, A., Zieger, N., Haasen, C., Karow, A., Dissociative symptoms in alcohol-dependent patients: associations with childhood trauma and substance abuse characteristics. Compr. Psychiatry 48 (2007), 539–545.
    • (2007) Compr. Psychiatry , vol.48 , pp. 539-545
    • Schäfer, I.1    Reininghaus, U.2    Langeland, W.3    Voss, A.4    Zieger, N.5    Haasen, C.6    Karow, A.7
  • 55
    • 0035672480 scopus 로고    scopus 로고
    • The childhood trauma questionnaire in a community sample: psychometric properties and normative data
    • Scher, C.D., Stein, M.B., Asmundson, G.J., McCreary, D.R., Forde, D.R., The childhood trauma questionnaire in a community sample: psychometric properties and normative data. J. Trauma. Stress 14 (2001), 843–857.
    • (2001) J. Trauma. Stress , vol.14 , pp. 843-857
    • Scher, C.D.1    Stein, M.B.2    Asmundson, G.J.3    McCreary, D.R.4    Forde, D.R.5
  • 57
    • 0032421570 scopus 로고    scopus 로고
    • The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10
    • Sheehan, D.V., Lecrubier, Y., Sheehan, K.H., Amorim, P., Janavas, J., Weiller, E., Hergueta, T., Baker, R., Dunbar, G.C., The Mini-International Neuropsychiatric Interview (M.I.N.I.): the development and validation of a structured diagnostic psychiatric interview for DSM-IV and ICD-10. J. Clin. Psychiatry 59:Suppl (1998), 22–33.
    • (1998) J. Clin. Psychiatry , vol.59 , pp. 22-33
    • Sheehan, D.V.1    Lecrubier, Y.2    Sheehan, K.H.3    Amorim, P.4    Janavas, J.5    Weiller, E.6    Hergueta, T.7    Baker, R.8    Dunbar, G.C.9
  • 58
    • 0035071957 scopus 로고    scopus 로고
    • A new statistical method for haplotype reconstruction from population data
    • Stephens, M., Smith, N.J., Donnelly, P., A new statistical method for haplotype reconstruction from population data. Am. J. Hum. Genet. 68 (2001), 978–989.
    • (2001) Am. J. Hum. Genet. , vol.68 , pp. 978-989
    • Stephens, M.1    Smith, N.J.2    Donnelly, P.3
  • 59
    • 84863884682 scopus 로고    scopus 로고
    • Multilocus genetic composite reflecting dopamine signaling capacity predicts reward circ;1; uitry responsivity
    • Stice, E., Yokum, S., Burger, K.S., Epstein, H., Smolen, A., Multilocus genetic composite reflecting dopamine signaling capacity predicts reward circ;1; uitry responsivity. J. Neurosci. 32 (2012), 10093–10100.
    • (2012) J. Neurosci. , vol.32 , pp. 10093-10100
    • Stice, E.1    Yokum, S.2    Burger, K.S.3    Epstein, H.4    Smolen, A.5
  • 60
    • 84922021698 scopus 로고    scopus 로고
    • A neural biomarker of psychological vulnerability to future life stress
    • Swartz, J.R., Knodt, A.R., Spenser, R.R., Hariri, A.R., A neural biomarker of psychological vulnerability to future life stress. Neuron 85 (2015), 505–511.
    • (2015) Neuron , vol.85 , pp. 505-511
    • Swartz, J.R.1    Knodt, A.R.2    Spenser, R.R.3    Hariri, A.R.4
  • 61
  • 62
    • 77957898055 scopus 로고    scopus 로고
    • A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing
    • Tottenham, N., Sheridan, M.A., A review of adversity, the amygdala and the hippocampus: a consideration of developmental timing. Front. Hum. Neurosci., 3, 2009, 68.
    • (2009) Front. Hum. Neurosci. , vol.3 , pp. 68
    • Tottenham, N.1    Sheridan, M.A.2
  • 63
    • 69949091530 scopus 로고    scopus 로고
    • Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity
    • Tyrka, A.R., Price, L.H., Gelernter, J., Schepker, C., Anderson, G.M., Carpenter, L.L., Interaction of childhood maltreatment with the corticotropin-releasing hormone receptor gene: effects on hypothalamic-pituitary-adrenal axis reactivity. Biol. Psychiatry 66 (2009), 681–685.
    • (2009) Biol. Psychiatry , vol.66 , pp. 681-685
    • Tyrka, A.R.1    Price, L.H.2    Gelernter, J.3    Schepker, C.4    Anderson, G.M.5    Carpenter, L.L.6
  • 65
    • 0028898610 scopus 로고
    • Testing a tripartite model: i. Evaluating the convergent and discriminant validity of anxiety and depression symptom scales
    • Watson, D., Weber, K., Assenheimer, J.S., Clark, L.a., Strauss, M.E., McCormick, R.a., Testing a tripartite model: i. Evaluating the convergent and discriminant validity of anxiety and depression symptom scales. J. Abnorm. Psychol. 104 (1995), 3–14.
    • (1995) J. Abnorm. Psychol. , vol.104 , pp. 3-14
    • Watson, D.1    Weber, K.2    Assenheimer, J.S.3    Clark, L.A.4    Strauss, M.E.5    McCormick, R.A.6
  • 66
    • 36048949270 scopus 로고    scopus 로고
    • Family history, early adversity and the hypothalamic-pituitary-adrenal (HPA) axis: mediation of the vulnerability to mood disorders
    • Watson, S., Owen, B.M., Gallagher, P., Hearn, A.J., Young, A.H., Ferrier, I.N., Family history, early adversity and the hypothalamic-pituitary-adrenal (HPA) axis: mediation of the vulnerability to mood disorders. Neuropsychiatr. Dis. Treat. 3 (2007), 647–653.
    • (2007) Neuropsychiatr. Dis. Treat. , vol.3 , pp. 647-653
    • Watson, S.1    Owen, B.M.2    Gallagher, P.3    Hearn, A.J.4    Young, A.H.5    Ferrier, I.N.6
  • 68
    • 84867301540 scopus 로고    scopus 로고
    • FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity
    • White, M.G., Bogdan, R., Fisher, P.M., Munoz, K.E., Williamson, D.E., Hariri, A.R., FKBP5 and emotional neglect interact to predict individual differences in amygdala reactivity. Genes Brain Behav. 11 (2012), 869–878.
    • (2012) Genes Brain Behav. , vol.11 , pp. 869-878
    • White, M.G.1    Bogdan, R.2    Fisher, P.M.3    Munoz, K.E.4    Williamson, D.E.5    Hariri, A.R.6
  • 69
    • 84857287526 scopus 로고    scopus 로고
    • Artifact Detection and QA Manual
    • Whitfield-Gabrieli, S., Artifact Detection and QA Manual. 2009.
    • (2009)
    • Whitfield-Gabrieli, S.1
  • 71
    • 10744232835 scopus 로고    scopus 로고
    • Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress
    • Wust, S., Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress. J. Clin. Endocrinol. Metab. 89 (2004), 565–573.
    • (2004) J. Clin. Endocrinol. Metab. , vol.89 , pp. 565-573
    • Wust, S.1
  • 72
    • 20044395965 scopus 로고    scopus 로고
    • Stress and the brain: from adaptation to disease
    • de Kloet, E.R., Joels, M., Holsboer, F., Stress and the brain: from adaptation to disease. Nat. Rev. Neurosci. 6 (2005), 463–475.
    • (2005) Nat. Rev. Neurosci. , vol.6 , pp. 463-475
    • de Kloet, E.R.1    Joels, M.2    Holsboer, F.3
  • 73
    • 77649271021 scopus 로고    scopus 로고
    • Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone
    • van Leeuwen, N., Kumsta, R., Entringer, S., de Kloet, E.R., Zitman, F.G., DeRijk, R.H., Wüst, S., Functional mineralocorticoid receptor (MR) gene variation influences the cortisol awakening response after dexamethasone. Psychoneuroendocrinology 35 (2010), 339–349.
    • (2010) Psychoneuroendocrinology , vol.35 , pp. 339-349
    • van Leeuwen, N.1    Kumsta, R.2    Entringer, S.3    de Kloet, E.R.4    Zitman, F.G.5    DeRijk, R.H.6    Wüst, S.7
  • 74
    • 79955521340 scopus 로고    scopus 로고
    • Human mineralocorticoid receptor (MR) gene haplotypes modulate MR expression and transactivation: implication for the stress response
    • van Leeuwen, N., Bellingrath, S., de Kloet, E.R., Zitman, F.G., DeRijk, R.H., Kudielka, B.M., Wust, S., Human mineralocorticoid receptor (MR) gene haplotypes modulate MR expression and transactivation: implication for the stress response. Psychoneuroendocrinology 36 (2011), 699–709.
    • (2011) Psychoneuroendocrinology , vol.36 , pp. 699-709
    • van Leeuwen, N.1    Bellingrath, S.2    de Kloet, E.R.3    Zitman, F.G.4    DeRijk, R.H.5    Kudielka, B.M.6    Wust, S.7


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