-
1
-
-
84875164559
-
The true cost of antimicrobial resistance
-
Smith, R., Coast, J. The true cost of antimicrobial resistance. BMJ 346, f1493 (2013).
-
(2013)
BMJ
, vol.346
, pp. f1493
-
-
Smith, R.1
Coast, J.2
-
2
-
-
85022171668
-
-
Centers for Disease Control and Prevention CDC, US Department of Health and Human Services Antibiotic Resistance Threats in the United States
-
Centers for Disease Control and Prevention. Antibiotic resistance threats in the United States, 2013. http://www. cdc. gov/drugresistance/pdf/ar-threats-2013-508. pdf (CDC, US Department of Health and Human Services, 2013).
-
-
-
-
4
-
-
77957980707
-
Origins and evolution of antibiotic resistance
-
Davies, J., Davies, D. Origins and evolution of antibiotic resistance. Microbiol. Mol. Biol. Rev. 74, 417-433 (2010).
-
(2010)
Microbiol. Mol. Biol. Rev.
, vol.74
, pp. 417-433
-
-
Davies, J.1
Davies, D.2
-
5
-
-
80053130409
-
Antibiotic resistance is ancient
-
D'Costa, V. M., et al. Antibiotic resistance is ancient. Nature 477, 457-461 (2011).
-
(2011)
Nature
, vol.477
, pp. 457-461
-
-
D'Costa, V.M.1
-
6
-
-
70349446050
-
The changing epidemiology of resistance
-
Hawkey, P. M., Jones, A. M. The changing epidemiology of resistance. J. Antimicrob. Chemother. 64 (Suppl. 1), i3-i10 (2009).
-
(2009)
J. Antimicrob. Chemother.
, vol.64
, pp. 3-10
-
-
Hawkey, P.M.1
Jones, A.M.2
-
7
-
-
84969157710
-
Interconnected microbiomes and resistomes in low-income human habitats
-
Pehrsson, E. C., et al. Interconnected microbiomes and resistomes in low-income human habitats. Nature 533, 212-216 (2016).
-
(2016)
Nature
, vol.533
, pp. 212-216
-
-
Pehrsson, E.C.1
-
8
-
-
84957433508
-
Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: A microbiological and molecular biological study
-
Liu, Y. Y., et al. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: A microbiological and molecular biological study. Lancet Infect. Dis. 16, 161-168 (2016).
-
(2016)
Lancet Infect. Dis.
, vol.16
, pp. 161-168
-
-
Liu, Y.Y.1
-
9
-
-
84974785712
-
Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015
-
Hasman, H., et al. Detection of mcr-1 encoding plasmid-mediated colistin-resistant Escherichia coli isolates from human bloodstream infection and imported chicken meat, Denmark 2015. Euro Surveill. http://dx. doi. org/10. 2807/1560-7917. ES. 2015. 20. 49. 30085 (2015).
-
(2015)
Euro Surveill.
-
-
Hasman, H.1
-
10
-
-
39749192528
-
Vancomycin-resistant Staphylococcus aureus in the United States 2002-2006
-
Sievert, D. M., et al. Vancomycin-resistant Staphylococcus aureus in the United States, 2002-2006. Clin. Infect. Dis. 46, 668-674 (2008).
-
(2008)
Clin. Infect. Dis.
, vol.46
, pp. 668-674
-
-
Sievert, D.M.1
-
11
-
-
84988442731
-
Multidrug-resistant Staphylococcus aureus India 2013-2015
-
Kumar, M. Multidrug-resistant Staphylococcus aureus, India, 2013-2015. Emerg. Infect. Dis. 22, 1666-1667 (2016).
-
(2016)
Emerg. Infect. Dis.
, vol.22
, pp. 1666-1667
-
-
Kumar, M.1
-
12
-
-
84957637760
-
Alternatives to antibiotics-a pipeline portfolio review
-
Czaplewski, L., et al. Alternatives to antibiotics-a pipeline portfolio review. Lancet Infect. Dis. 16, 239-251 (2016).
-
(2016)
Lancet Infect. Dis.
, vol.16
, pp. 239-251
-
-
Czaplewski, L.1
-
13
-
-
34548108138
-
Targeting virulence: A new paradigm for antimicrobial therapy
-
Clatworthy, A. E., Pierson, E., Hung, D. T. Targeting virulence: A new paradigm for antimicrobial therapy. Nat. Chem. Biol. 3, 541-548 (2007).
-
(2007)
Nat. Chem. Biol.
, vol.3
, pp. 541-548
-
-
Clatworthy, A.E.1
Pierson, E.2
Hung, D.T.3
-
14
-
-
0032765322
-
Host-pathogen interactions: Redefining the basic concepts of virulence and pathogenicity
-
Casadevall, A., Pirofski, L. A. Host-pathogen interactions: Redefining the basic concepts of virulence and pathogenicity. Infect. Immun. 67, 3703-3713 (1999).
-
(1999)
Infect. Immun.
, vol.67
, pp. 3703-3713
-
-
Casadevall, A.1
Pirofski, L.A.2
-
15
-
-
84893786916
-
Targeting virulence: Can we make evolution-proof drugs Nat
-
Allen, R. C., Popat, R., Diggle, S. P., Brown, S. P. Targeting virulence: Can we make evolution-proof drugs Nat. Rev. Microbiol. 12, 300-308 (2014).
-
(2014)
Rev. Microbiol.
, vol.12
, pp. 300-308
-
-
Allen, R.C.1
Popat, R.2
Diggle, S.P.3
Brown, S.P.4
-
16
-
-
84979609905
-
Cospeciation of gut microbiota with hominids
-
Moeller, A. H., et al. Cospeciation of gut microbiota with hominids. Science 353, 380-382 (2016).
-
(2016)
Science
, vol.353
, pp. 380-382
-
-
Moeller, A.H.1
-
17
-
-
84858439578
-
The human microbiome: At the interface of health and disease
-
Cho, I., Blaser, M. J. The human microbiome: At the interface of health and disease. Nat. Rev. Genet. 13, 260-270 (2012).
-
(2012)
Nat. Rev. Genet.
, vol.13
, pp. 260-270
-
-
Cho, I.1
Blaser, M.J.2
-
18
-
-
84931275007
-
Pheromone killing of multidrug-resistant Enterococcus faecalis V583 by native commensal strains
-
Gilmore, M. S., et al. Pheromone killing of multidrug-resistant Enterococcus faecalis V583 by native commensal strains. Proc. Natl Acad. Sci. USA 112, 7273-7278 (2015).
-
(2015)
Proc. Natl Acad. Sci. USA
, vol.112
, pp. 7273-7278
-
-
Gilmore, M.S.1
-
19
-
-
84945295917
-
Interactions between the gastrointestinal microbiome and Clostridium difficile
-
Theriot, C. M., Young, V. B. Interactions between the gastrointestinal microbiome and Clostridium difficile. Annu. Rev. Microbiol. 69, 445-461 (2015).
-
(2015)
Annu. Rev. Microbiol.
, vol.69
, pp. 445-461
-
-
Theriot, C.M.1
Young, V.B.2
-
20
-
-
84907528345
-
Effects of antibiotics on human microbiota and subsequent disease
-
Keeney, K. M., Yurist-Doutsch, S., Arrieta, M. C., Finlay, B. B. Effects of antibiotics on human microbiota and subsequent disease. Annu. Rev. Microbiol. 68, 217-235 (2014).
-
(2014)
Annu. Rev. Microbiol.
, vol.68
, pp. 217-235
-
-
Keeney, K.M.1
Yurist-Doutsch, S.2
Arrieta, M.C.3
Finlay, B.B.4
-
21
-
-
33845903833
-
Drugs for bad bugs: Confronting the challenges of antibacterial discovery
-
Payne, D. J., Gwynn, M. N., Holmes, D. J., Pompliano, D. L. Drugs for bad bugs: Confronting the challenges of antibacterial discovery. Nat. Rev. Drug Discov. 6, 29-40 (2007).
-
(2007)
Nat. Rev. Drug Discov.
, vol.6
, pp. 29-40
-
-
Payne, D.J.1
Gwynn, M.N.2
Holmes, D.J.3
Pompliano, D.L.4
-
22
-
-
84922937832
-
A new antibiotic kills pathogens without detectable resistance
-
Ling, L. L., et al. A new antibiotic kills pathogens without detectable resistance. Nature 517, 455-459 (2015).
-
(2015)
Nature
, vol.517
, pp. 455-459
-
-
Ling, L.L.1
-
23
-
-
84939511930
-
Antibacterial monoclonal antibodies: The next generation Curr
-
DiGiandomenico, A., Sellman, B. R. Antibacterial monoclonal antibodies: The next generation Curr. Opin. Microbiol. 27, 78-85 (2015).
-
(2015)
Opin. Microbiol.
, vol.27
, pp. 78-85
-
-
Di Giandomenico, A.1
Sellman, B.R.2
-
24
-
-
58549116149
-
Virulence evolution and the trade-off hypo thesis: History, current state of affairs and the future
-
Alizon, S., Hurford, A., Mideo, N., Van Baalen, M. Virulence evolution and the trade-off hypothesis: History, current state of affairs and the future. J. Evol. Biol. 22, 245-259 (2009).
-
(2009)
J. Evol. Biol.
, vol.22
, pp. 245-259
-
-
Alizon, S.1
Hurford, A.2
Mideo, N.3
Van Baalen, M.4
-
25
-
-
0035425835
-
Host-pathogen interactions: The attributes of virulence
-
Casadevall, A., Pirofski, L. Host-pathogen interactions: The attributes of virulence. J. Infect. Dis. 184, 337-344 (2001).
-
(2001)
J. Infect. Dis.
, vol.184
, pp. 337-344
-
-
Casadevall, A.1
Pirofski, L.2
-
26
-
-
42549171131
-
Federal funding for the study of antimicrobial resistance in nosocomial pathogens: No ESKAPE
-
Rice, L. B. Federal funding for the study of antimicrobial resistance in nosocomial pathogens: No ESKAPE. J. Infect. Dis. 197, 1079-1081 (2008).
-
(2008)
J. Infect. Dis.
, vol.197
, pp. 1079-1081
-
-
Rice, L.B.1
-
27
-
-
84891554851
-
Molecular characterization of a novel botulinum neurotoxin type H gene
-
Dover, N., Barash, J. R., Hill, K. K., Xie, G., Arnon, S. S. Molecular characterization of a novel botulinum neurotoxin type H gene. J. Infect. Dis. 209, 192-202 (2014).
-
(2014)
J. Infect. Dis.
, vol.209
, pp. 192-202
-
-
Dover, N.1
Barash, J.R.2
Hill, K.K.3
Xie, G.4
Arnon, S.S.5
-
28
-
-
1342323663
-
Identification of the major steps in botulinum toxin action
-
Simpson, L. L. Identification of the major steps in botulinum toxin action. Annu. Rev. Pharmacol. Toxicol. 44, 167-193 (2004).
-
(2004)
Annu. Rev. Pharmacol. Toxicol.
, vol.44
, pp. 167-193
-
-
Simpson, L.L.1
-
29
-
-
0020073392
-
Bacterial toxins: A table of lethal amounts
-
Gill, D. M. Bacterial toxins: A table of lethal amounts. Microbiol. Rev. 46, 86-94 (1982).
-
(1982)
Microbiol. Rev.
, vol.46
, pp. 86-94
-
-
Gill, D.M.1
-
30
-
-
0035961566
-
Botulinum toxin as a biological weapon: Medical and public health management
-
Arnon, S. S., et al. Botulinum toxin as a biological weapon: Medical and public health management. JAMA 285, 1059-1070 (2001).
-
(2001)
JAMA
, vol.285
, pp. 1059-1070
-
-
Arnon, S.S.1
-
31
-
-
4444322182
-
Foodborne botulism in the United States 1990-2000
-
Sobel, J., Tucker, N., Sulka, A., McLaughlin, J., Maslanka, S. Foodborne botulism in the United States, 1990-2000. Emerg. Infect. Dis. 10, 1606-1611 (2004).
-
(2004)
Emerg. Infect. Dis.
, vol.10
, pp. 1606-1611
-
-
Sobel, J.1
Tucker, N.2
Sulka, A.3
McLaughlin, J.4
Maslanka, S.5
-
32
-
-
32044452414
-
Human botulism immune globulin for the treatment of infant botulism
-
Arnon, S. S., Schechter, R., Maslanka, S. E., Jewell, N. P., Hatheway, C. L. Human botulism immune globulin for the treatment of infant botulism. N. Engl. J. Med. 354, 462-471 (2006).
-
(2006)
N. Engl. J. Med.
, vol.354
, pp. 462-471
-
-
Arnon, S.S.1
Schechter, R.2
Maslanka, S.E.3
Jewell, N.P.4
Hatheway, C.L.5
-
33
-
-
84960350022
-
A novel botulinum neurotoxin, previously reported as serotype H, has a hybrid-like structure with regions of similarity to the structures of serotypes A and F and is neutralized with serotype A antitoxin
-
Maslanka, S. E., et al. A novel botulinum neurotoxin, previously reported as serotype H, has a hybrid-like structure with regions of similarity to the structures of serotypes A and F and is neutralized with serotype A antitoxin. J. Infect. Dis. 213, 379-385 (2016).
-
(2016)
J. Infect. Dis.
, vol.213
, pp. 379-385
-
-
Maslanka, S.E.1
-
34
-
-
33644897590
-
Systematic review: A century of inhalational anthrax cases from 1900 to 2005
-
Holty, J. E., et al. Systematic review: A century of inhalational anthrax cases from 1900 to 2005. Ann. Intern. Med. 144, 270-280 (2006).
-
(2006)
Ann. Intern. Med.
, vol.144
, pp. 270-280
-
-
Holty, J.E.1
-
35
-
-
80052155168
-
Monoclonal antibody therapies against anthrax
-
Chen, Z., Moayeri, M., Purcell, R. Monoclonal antibody therapies against anthrax. Toxins (Basel) 3, 1004-1019 (2011).
-
(2011)
Toxins (Basel)
, vol.3
, pp. 1004-1019
-
-
Chen, Z.1
Moayeri, M.2
Purcell, R.3
-
37
-
-
84888432401
-
Hijacking multivesicular bodies enables long-term and exosome-mediated long-distance action of anthrax toxin
-
Abrami, L., et al. Hijacking multivesicular bodies enables long-term and exosome-mediated long-distance action of anthrax toxin. Cell Rep. 5, 986-996 (2013).
-
(2013)
Cell Rep.
, vol.5
, pp. 986-996
-
-
Abrami, L.1
-
38
-
-
67650500264
-
Raxibacumab for the treatment of inhalational anthrax
-
Migone, T. S., et al. Raxibacumab for the treatment of inhalational anthrax. N. Engl. J. Med. 361, 135-144 (2009).
-
(2009)
N. Engl. J. Med.
, vol.361
, pp. 135-144
-
-
Migone, T.S.1
-
39
-
-
84963728734
-
Obiltoxaximab: First global approval
-
Greig, S. L. Obiltoxaximab: First global approval. Drugs 76, 823-830 (2016).
-
(2016)
Drugs
, vol.76
, pp. 823-830
-
-
Greig, S.L.1
-
40
-
-
84992379403
-
Obiltoxaximab prevents disseminated Bacillus anthracis infection and improves survival during pre-and post-exposure prophylaxis in animal models of inhalational anthrax
-
Yamamoto, B. J., et al. Obiltoxaximab prevents disseminated Bacillus anthracis infection and improves survival during pre-and post-exposure prophylaxis in animal models of inhalational anthrax. Antimicrob. Agents Chemother. 60, 5796-5805 (2016).
-
(2016)
Antimicrob. Agents Chemother.
, vol.60
, pp. 5796-5805
-
-
Yamamoto, B.J.1
-
41
-
-
0041806527
-
Poly(-D-glutamic acid) protein conjugates induce IgG antibodies in mice to the capsule of Bacillus anthracis: A potential addition to the anthrax vaccine
-
Schneerson, R., et al. Poly(-D-glutamic acid) protein conjugates induce IgG antibodies in mice to the capsule of Bacillus anthracis: A potential addition to the anthrax vaccine. Proc. Natl Acad. Sci. USA 100, 8945-8950 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, pp. 8945-8950
-
-
Schneerson, R.1
-
42
-
-
79551679357
-
Pre-and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule
-
Chen, Z., et al. Pre-and postexposure protection against virulent anthrax infection in mice by humanized monoclonal antibodies to Bacillus anthracis capsule. Proc. Natl Acad. Sci. USA 108, 739-744 (2011).
-
(2011)
Proc. Natl Acad. Sci. USA
, vol.108
, pp. 739-744
-
-
Chen, Z.1
-
43
-
-
33845978057
-
Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule
-
Kozel, T. R., et al. Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule. Infect. Immun. 75, 152-163 (2007).
-
(2007)
Infect. Immun.
, vol.75
, pp. 152-163
-
-
Kozel, T.R.1
-
44
-
-
84928023485
-
Clostridium difficile infection
-
Leffler, D. A., Lamont, J. T. Clostridium difficile infection. N. Engl. J. Med. 372, 1539-1548 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 1539-1548
-
-
Leffler, D.A.1
Lamont, J.T.2
-
45
-
-
84984637680
-
Clostridium difficile colitis: Pathogenesis and host defence
-
Abt, M. C., McKenney, P. T., Pamer, E. G. Clostridium difficile colitis: Pathogenesis and host defence. Nat. Rev. Microbiol. 10, 609-620 (2016).
-
(2016)
Nat. Rev. Microbiol.
, vol.10
, pp. 609-620
-
-
Abt, M.C.1
McKenney, P.T.2
Pamer, E.G.3
-
46
-
-
84923775846
-
Burden of Clostridium difficile infection in the United States
-
Lessa, F. C., et al. Burden of Clostridium difficile infection in the United States. N. Engl. J. Med. 372, 825-834 (2015).
-
(2015)
N. Engl. J. Med.
, vol.372
, pp. 825-834
-
-
Lessa, F.C.1
-
47
-
-
42449157632
-
Increased sporulation rate of epidemic Clostridium difficile Type 027/NAP1
-
Akerlund, T., et al. Increased sporulation rate of epidemic Clostridium difficile Type 027/NAP1. J. Clin. Microbiol. 46, 1530-1533 (2008).
-
(2008)
J. Clin. Microbiol.
, vol.46
, pp. 1530-1533
-
-
Akerlund, T.1
-
48
-
-
84855510455
-
The role of toxin A and toxin B in the virulence of Clostridium difficile
-
Carter, G. P., Rood, J. I., Lyras, D. The role of toxin A and toxin B in the virulence of Clostridium difficile. Trends Microbiol. 20, 21-29 (2012).
-
(2012)
Trends Microbiol.
, vol.20
, pp. 21-29
-
-
Carter, G.P.1
Rood, J.I.2
Lyras, D.3
-
49
-
-
84905057299
-
Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: Results from two multinational, randomized, controlled trials
-
Johnson, S., et al. Vancomycin, metronidazole, or tolevamer for Clostridium difficile infection: Results from two multinational, randomized, controlled trials. Clin. Infect. Dis. 59, 345-354 (2014).
-
(2014)
Clin. Infect. Dis.
, vol.59
, pp. 345-354
-
-
Johnson, S.1
-
50
-
-
74849098405
-
Treatment with monoclonal antibodies against Clostridium difficile toxins
-
Lowy, I., et al. Treatment with monoclonal antibodies against Clostridium difficile toxins. N. Engl. J. Med. 362, 197-205 (2010).
-
(2010)
N. Engl. J. Med.
, vol.362
, pp. 197-205
-
-
Lowy, I.1
-
51
-
-
84942543705
-
A small-molecule antivirulence agent for treating Clostridium difficile infection
-
Bender, K. O., et al. A small-molecule antivirulence agent for treating Clostridium difficile infection. Sci. Transl Med. 7, 306ra148 (2015).
-
(2015)
Sci. Transl Med.
, vol.7
, pp. 306ra148
-
-
Bender, K.O.1
-
52
-
-
67749132626
-
Development of ebselen, a glutathione peroxidase mimic, for the prevention and treatment of noise-induced hearing loss
-
Lynch, E., Kil, J. Development of ebselen, a glutathione peroxidase mimic, for the prevention and treatment of noise-induced hearing loss. Semin. Hear. 30, 47-55 (2009).
-
(2009)
Semin. Hear.
, vol.30
, pp. 47-55
-
-
Lynch, E.1
Kil, J.2
-
53
-
-
84961720977
-
Ebselen and analogs as inhibitors of Bacillus anthracis thioredoxin reductase and bactericidal antibacterials targeting Bacillus species. Staphylococcus aureus and Mycobacterium tuberculosis
-
Gustafsson, T. N., et al. Ebselen and analogs as inhibitors of Bacillus anthracis thioredoxin reductase and bactericidal antibacterials targeting Bacillus species. Staphylococcus aureus and Mycobacterium tuberculosis. Biochim. Biophys. Acta 1860, 1265-1271 (2016).
-
(2016)
Biochim. Biophys. Acta
, vol.1860
, pp. 1265-1271
-
-
Gustafsson, T.N.1
-
54
-
-
84933054771
-
Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections
-
Thangamani, S., Younis, W., Seleem, M. N. Repurposing ebselen for treatment of multidrug-resistant staphylococcal infections. Sci. Rep. 5, 11596 (2015).
-
(2015)
Sci. Rep.
, vol.5
, pp. 11596
-
-
Thangamani, S.1
Younis, W.2
Seleem, M.N.3
-
55
-
-
84986563686
-
Accessory gene regulator-1 locus is essential for virulence and pathogenesis of Clostridium difficile
-
Darkoh, C., Odo, C., DuPont, H. L. Accessory gene regulator-1 locus is essential for virulence and pathogenesis of Clostridium difficile. mBio 7, e01237-16 (2016).
-
(2016)
MBio
, vol.7
, pp. e01237-e01316
-
-
Darkoh, C.1
Odo, C.2
DuPont, H.L.3
-
56
-
-
84881238786
-
The agr locus regulates virulence and colonization genes in Clostridium difficile 027
-
Martin, M. J., et al. The agr locus regulates virulence and colonization genes in Clostridium difficile 027. J. Bacteriol. 195, 3672-3681 (2013).
-
(2013)
J. Bacteriol.
, vol.195
, pp. 3672-3681
-
-
Martin, M.J.1
-
57
-
-
84888990813
-
National burden of invasive methicillin-resistant Staphylococcus aureus infections United States 2011
-
Dantes, R., et al. National burden of invasive methicillin-resistant Staphylococcus aureus infections, United States, 2011. JAMA Intern. Med. 173, 1970-1978 (2013).
-
(2013)
JAMA Intern. Med.
, vol.173
, pp. 1970-1978
-
-
Dantes, R.1
-
58
-
-
77957971178
-
Basis of virulence in community-associated methicillin-resistant Staphylococcus aureus
-
Otto, M. Basis of virulence in community-associated methicillin-resistant Staphylococcus aureus. Annu. Rev. Microbiol. 64, 143-162 (2010).
-
(2010)
Annu. Rev. Microbiol.
, vol.64
, pp. 143-162
-
-
Otto, M.1
-
59
-
-
84860690538
-
MRSA epidemic linked to a quickly spreading colonization and virulence determinant
-
Li, M., et al. MRSA epidemic linked to a quickly spreading colonization and virulence determinant. Nat. Med. 18, 816-819 (2012).
-
(2012)
Nat. Med.
, vol.18
, pp. 816-819
-
-
Li, M.1
-
60
-
-
84882632324
-
Complete genome sequence of a Panton-Valentine leukocidin-negative community-associated methicillin-resistant Staphylococcus aureus strain of sequence type 72 from Korea
-
Chen, Y., Chatterjee, S. S., Porcella, S. F., Yu, Y. S., Otto, M. Complete genome sequence of a Panton-Valentine leukocidin-negative community-associated methicillin-resistant Staphylococcus aureus strain of sequence type 72 from Korea. PLoS ONE 8, e72803 (2013).
-
(2013)
PLoS ONE
, vol.8
, pp. e72803
-
-
Chen, Y.1
Chatterjee, S.S.2
Porcella, S.F.3
Yu, Y.S.4
Otto, M.5
-
61
-
-
84974795084
-
Virulence determinants associated with the Asian community-associated methicillin-resistant Staphylococcus aureus lineage ST59
-
Li, M., et al. Virulence determinants associated with the Asian community-associated methicillin-resistant Staphylococcus aureus lineage ST59. Sci. Rep. 6, 27899 (2016).
-
(2016)
Sci. Rep.
, vol.6
, pp. 27899
-
-
Li, M.1
-
62
-
-
33747343208
-
Methicillin-resistant S. Aureus infections among patients in the emergency department
-
Moran, G. J., et al. Methicillin-resistant S. aureus infections among patients in the emergency department. N. Engl. J. Med. 355, 666-674 (2006).
-
(2006)
N. Engl. J. Med.
, vol.355
, pp. 666-674
-
-
Moran, G.J.1
-
63
-
-
0025787798
-
Alpha-toxin of Staphylococcus aureus
-
Bhakdi, S., Tranum-Jensen, J. Alpha-toxin of Staphylococcus aureus. Microbiol. Rev. 55, 733-751 (1991).
-
(1991)
Microbiol. Rev.
, vol.55
, pp. 733-751
-
-
Bhakdi, S.1
Tranum-Jensen, J.2
-
64
-
-
84908178834
-
Mechanisms of neutralization of a human anti-alpha-toxin antibody
-
Oganesyan, V., et al. Mechanisms of neutralization of a human anti-alpha-toxin antibody. J. Biol. Chem. 289, 29874-29880 (2014).
-
(2014)
J. Biol. Chem.
, vol.289
, pp. 29874-29880
-
-
Oganesyan, V.1
-
65
-
-
84919473548
-
Characterization of alpha-toxin HLA gene variants, alpha-toxin expression levels, levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with Staphylococcus aureus bacteremia
-
Sharma-Kuinkel, B. K., et al. Characterization of alpha-toxin hla gene variants, alpha-toxin expression levels, levels of antibody to alpha-toxin in hemodialysis and postsurgical patients with Staphylococcus aureus bacteremia. J. Clin. Microbiol. 53, 227-236 (2015).
-
(2015)
J. Clin. Microbiol.
, vol.53
, pp. 227-236
-
-
Sharma-Kuinkel, B.K.1
-
66
-
-
84921376947
-
Five birds one stone: Neutralization of alpha-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody
-
Rouha, H., et al. Five birds, one stone: Neutralization of alpha-hemolysin and 4 bi-component leukocidins of Staphylococcus aureus with a single human monoclonal antibody. mAbs 7, 243-254 (2015).
-
(2015)
MAbs
, vol.7
, pp. 243-254
-
-
Rouha, H.1
-
67
-
-
84984871095
-
Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies
-
Badarau, A., et al. Context matters: The importance of dimerization-induced conformation of the LukGH leukocidin of Staphylococcus aureus for the generation of neutralizing antibodies. mAbs 8, 1347-1360 (2016).
-
(2016)
MAbs
, vol.8
, pp. 1347-1360
-
-
Badarau, A.1
-
68
-
-
84877757139
-
Staphylococcus aureus hemolysins, bi-component leukocidins, cytolytic peptides: A redundant arsenal of membrane-damaging virulence factors Front
-
Vandenesch, F., Lina, G., Henry, T. Staphylococcus aureus hemolysins, bi-component leukocidins, cytolytic peptides: A redundant arsenal of membrane-damaging virulence factors Front. Cell. Infect. Microbiol. 2, 12 (2012).
-
(2012)
Cell. Infect. Microbiol.
, vol.2
, pp. 12
-
-
Vandenesch, F.1
Lina, G.2
Henry, T.3
-
69
-
-
0026638608
-
Sorting of protein A to the staphylococcal cell wall
-
Schneewind, O., Model, P., Fischetti, V. A. Sorting of protein A to the staphylococcal cell wall. Cell 70, 267-281 (1992).
-
(1992)
Cell
, vol.70
, pp. 267-281
-
-
Schneewind, O.1
Model, P.2
Fischetti, V.A.3
-
70
-
-
0034625174
-
Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections
-
Mazmanian, S. K., Liu, G., Jensen, E. R., Lenoy, E., Schneewind, O. Staphylococcus aureus sortase mutants defective in the display of surface proteins and in the pathogenesis of animal infections. Proc. Natl Acad. Sci. USA 97, 5510-5515 (2000).
-
(2000)
Proc. Natl Acad. Sci. USA
, vol.97
, pp. 5510-5515
-
-
Mazmanian, S.K.1
Liu, G.2
Jensen, E.R.3
Lenoy, E.4
Schneewind, O.5
-
71
-
-
84907222984
-
Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase
-
Zhang, J., et al. Antiinfective therapy with a small molecule inhibitor of Staphylococcus aureus sortase. Proc. Natl Acad. Sci. USA 111, 13517-13522 (2014).
-
(2014)
Proc. Natl Acad. Sci. USA
, vol.111
, pp. 13517-13522
-
-
Zhang, J.1
-
72
-
-
0030838740
-
Bacterial interference caused by autoinducing peptide variants
-
Ji, G., Beavis, R., Novick, R. P. Bacterial interference caused by autoinducing peptide variants. Science 276, 2027-2030 (1997).
-
(1997)
Science
, vol.276
, pp. 2027-2030
-
-
Ji, G.1
Beavis, R.2
Novick, R.P.3
-
73
-
-
0033754248
-
Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus
-
Jarraud, S., et al. Exfoliatin-producing strains define a fourth agr specificity group in Staphylococcus aureus. J. Bacteriol. 182, 6517-6522 (2000).
-
(2000)
J. Bacteriol.
, vol.182
, pp. 6517-6522
-
-
Jarraud, S.1
-
74
-
-
84903487653
-
Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance
-
Sully, E. K., et al. Selective chemical inhibition of agr quorum sensing in Staphylococcus aureus promotes host defense with minimal impact on resistance. PLoS Pathog. 10, e1004174 (2014).
-
(2014)
PLoS Pathog.
, vol.10
, pp. e1004174
-
-
Sully, E.K.1
-
75
-
-
0037325045
-
Aeruginosa quorum-sensing systems and virulence
-
Smith, R. S., Iglewski, B. H. P. aeruginosa quorum-sensing systems and virulence. Curr. Opin. Microbiol. 6, 56-60 (2003).
-
(2003)
Curr. Opin. Microbiol.
, vol.6
, pp. 56-60
-
-
Smith, R.S.1
Iglewski, B.H.P.2
-
76
-
-
14544284036
-
The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: Multiple quorum sensing-regulated genes are modulated without affecting lasRI, rhlRI or the production of N-acyl-L-homoserine lactones
-
Deziel, E., et al. The contribution of MvfR to Pseudomonas aeruginosa pathogenesis and quorum sensing circuitry regulation: Multiple quorum sensing-regulated genes are modulated without affecting lasRI, rhlRI or the production of N-acyl-L-homoserine lactones. Mol. Microbiol. 55, 998-1014 (2005).
-
(2005)
Mol. Microbiol.
, vol.55
, pp. 998-1014
-
-
Deziel, E.1
-
77
-
-
84879120487
-
A cell-cell communication signal integrates quorum sensing and stress response
-
Lee, J., et al. A cell-cell communication signal integrates quorum sensing and stress response. Nat. Chem. Biol. 9, 339-343 (2013).
-
(2013)
Nat. Chem. Biol.
, vol.9
, pp. 339-343
-
-
Lee, J.1
-
78
-
-
84969659996
-
Novel strategies for the treatment of Pseudomonas aeruginosa infections
-
Wagner, S., et al. Novel strategies for the treatment of Pseudomonas aeruginosa infections. J. Med. Chem. 59, 5929-5969 (2016).
-
(2016)
J. Med. Chem.
, vol.59
, pp. 5929-5969
-
-
Wagner, S.1
-
80
-
-
0035007794
-
Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa
-
Tateda, K., et al. Azithromycin inhibits quorum sensing in Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 45, 1930-1933 (2001).
-
(2001)
Antimicrob. Agents Chemother.
, vol.45
, pp. 1930-1933
-
-
Tateda, K.1
-
81
-
-
71249096926
-
A low concentration of azithromycin inhibits the mRNA expression of N-acyl homoserine lactone synthesis enzymes, upstream of lasI or rhlI, in Pseudomonas aeruginosa
-
Kai, T., et al. A low concentration of azithromycin inhibits the mRNA expression of N-acyl homoserine lactone synthesis enzymes, upstream of lasI or rhlI, in Pseudomonas aeruginosa. Pulm. Pharmacol. Ther. 22, 483-486 (2009).
-
(2009)
Pulm. Pharmacol. Ther.
, vol.22
, pp. 483-486
-
-
Kai, T.1
-
82
-
-
77954053982
-
Quorum sensing inhibition selects for virulence and cooperation in Pseudomonas aeruginosa
-
Kohler, T., Perron, G. G., Buckling, A., van Delden, C. Quorum sensing inhibition selects for virulence and cooperation in Pseudomonas aeruginosa. PLoS Pathog. 6, e1000883 (2010).
-
(2010)
PLoS Pathog.
, vol.6
, pp. e1000883
-
-
Kohler, T.1
Perron, G.G.2
Buckling, A.3
Van Delden, C.4
-
83
-
-
84886686961
-
Resistance to the quorum-quenching compounds brominated furanone C-30 and 5-fluorouracil in Pseudomonas aeruginosa clinical isolates
-
Garcia-Contreras, R., et al. Resistance to the quorum-quenching compounds brominated furanone C-30 and 5-fluorouracil in Pseudomonas aeruginosa clinical isolates. Pathog. Dis. 68, 8-11 (2013).
-
(2013)
Pathog. Dis.
, vol.68
, pp. 8-11
-
-
Garcia-Contreras, R.1
-
84
-
-
33744814106
-
Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients
-
Smith, E. E., et al. Genetic adaptation by Pseudomonas aeruginosa to the airways of cystic fibrosis patients. Proc. Natl Acad. Sci. USA 103, 8487-8492 (2006).
-
(2006)
Proc. Natl Acad. Sci. USA
, vol.103
, pp. 8487-8492
-
-
Smith, E.E.1
-
85
-
-
85028139131
-
Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis
-
Marvig, R. L., Sommer, L. M., Molin, S., Johansen, H. K. Convergent evolution and adaptation of Pseudomonas aeruginosa within patients with cystic fibrosis. Nat. Genet. 47, 57-64 (2015).
-
(2015)
Nat. Genet.
, vol.47
, pp. 57-64
-
-
Marvig, R.L.1
Sommer, L.M.2
Molin, S.3
Johansen, H.K.4
-
86
-
-
84937901772
-
Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity
-
Starkey, M., et al. Identification of anti-virulence compounds that disrupt quorum-sensing regulated acute and persistent pathogenicity. PLoS Pathog. 10, e1004321 (2014).
-
(2014)
PLoS Pathog.
, vol.10
, pp. e1004321
-
-
Starkey, M.1
-
87
-
-
84864291211
-
Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening
-
DiGiandomenico, A., et al. Identification of broadly protective human antibodies to Pseudomonas aeruginosa exopolysaccharide Psl by phenotypic screening. J. Exp. Med. 209, 1273-1287 (2012).
-
(2012)
J. Exp. Med.
, vol.209
, pp. 1273-1287
-
-
Di Giandomenico, A.1
-
88
-
-
84905388478
-
A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models
-
Warrener, P., et al. A novel anti-PcrV antibody providing enhanced protection against Pseudomonas aeruginosa in multiple animal infection models. Antimicrob. Agents Chemother. 58, 4384-4391 (2014).
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 4384-4391
-
-
Warrener, P.1
-
89
-
-
84910673427
-
A multifunctional bispecific antibody protects against Pseudomonas aeruginosa
-
DiGiandomenico, A., et al. A multifunctional bispecific antibody protects against Pseudomonas aeruginosa. Sci. Transl Med. 6, 262ra155 (2014).
-
(2014)
Sci. Transl Med.
, vol.6
, pp. 262ra155
-
-
Di Giandomenico, A.1
-
90
-
-
1842508193
-
Pathogenic Escherichia coli
-
Kaper, J. B., Nataro, J. P., Mobley, H. L. Pathogenic Escherichia coli. Nat. Rev. Microbiol. 2, 123-140 (2004).
-
(2004)
Nat. Rev. Microbiol.
, vol.2
, pp. 123-140
-
-
Kaper, J.B.1
Nataro, J.P.2
Mobley, H.L.3
-
91
-
-
84975241561
-
Escherichia coli harboring mcr-1 and blaCTX-M on a novel IncF plasmid: First report of mcr-1 in the United States
-
McGann, P., et al. Escherichia coli harboring mcr-1 and blaCTX-M on a novel IncF plasmid: First report of mcr-1 in the United States. Antimicrob. Agents Chemother. 60, 4420-4421 (2016).
-
(2016)
Antimicrob. Agents Chemother.
, vol.60
, pp. 4420-4421
-
-
McGann, P.1
-
92
-
-
84983353729
-
Detection of mcr-1 among Escherichia coli clinical isolates collected worldwide as part of the SENTRY antimicrobial surveillance program in 2014 and 2015
-
Castanheira, M., et al. Detection of mcr-1 among Escherichia coli clinical isolates collected worldwide as part of the SENTRY antimicrobial surveillance program in 2014 and 2015. Antimicrob. Agents Chemother. 60, 5623-5624 (2016).
-
(2016)
Antimicrob. Agents Chemother.
, vol.60
, pp. 5623-5624
-
-
Castanheira, M.1
-
93
-
-
84986540397
-
Colistin-and carbapenem-resistant Escherichia coli harboring mcr-1 and blaNDM-5 causing a complicated urinary tract infection in a patient from the United States
-
Mediavilla, J. R., et al. Colistin-and carbapenem-resistant Escherichia coli harboring mcr-1 and blaNDM-5, causing a complicated urinary tract infection in a patient from the United States. mBio 7, e01191-16 (2016).
-
(2016)
MBio
, vol.7
, pp. e01191-e01216
-
-
Mediavilla, J.R.1
-
94
-
-
77952711660
-
Transfer of carbapenem-resistant plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in patient
-
Goren, M. G., et al. Transfer of carbapenem-resistant plasmid from Klebsiella pneumoniae ST258 to Escherichia coli in patient. Emerg. Infect. Dis. 16, 1014-1017 (2010).
-
(2010)
Emerg. Infect. Dis.
, vol.16
, pp. 1014-1017
-
-
Goren, M.G.1
-
95
-
-
84858636056
-
Nosocomial outbreak of carbapenem-resistant Enterobacter cloacae highlighting the interspecies transferability of the blaOXA-48 gene in the gut flora
-
Cremet, L., et al. Nosocomial outbreak of carbapenem-resistant Enterobacter cloacae highlighting the interspecies transferability of the blaOXA-48 gene in the gut flora. J. Antimicrob. Chemother. 67, 1041-1043 (2012).
-
(2012)
J. Antimicrob. Chemother.
, vol.67
, pp. 1041-1043
-
-
Cremet, L.1
-
96
-
-
0027185787
-
Endothelial heterogeneity in Shiga toxin receptors and responses
-
Obrig, T. G., et al. Endothelial heterogeneity in Shiga toxin receptors and responses. J. Biol. Chem. 268, 15484-15488 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 15484-15488
-
-
Obrig, T.G.1
-
97
-
-
84862159579
-
Risk factors for the hemolytic uremic syndrome in children infected with Escherichia coli O157: H7: A multivariable analysis
-
Wong, C. S., et al. Risk factors for the hemolytic uremic syndrome in children infected with Escherichia coli O157:H7: A multivariable analysis. Clin. Infect. Dis. 55, 33-41 (2012).
-
(2012)
Clin. Infect. Dis.
, vol.55
, pp. 33-41
-
-
Wong, C.S.1
-
98
-
-
0034056335
-
Quinolone antibiotics induce Shiga toxin-encoding bacteriophages, toxin production, death in mice
-
Zhang, X., et al. Quinolone antibiotics induce Shiga toxin-encoding bacteriophages, toxin production, death in mice. J. Infect. Dis. 181, 664-670 (2000).
-
(2000)
J. Infect. Dis.
, vol.181
, pp. 664-670
-
-
Zhang, X.1
-
99
-
-
0026598420
-
Effect of subinhibitory concentrations of antibiotics on extracellular Shiga-like toxin I
-
Walterspiel, J. N., Ashkenazi, S., Morrow, A. L., Cleary, T. G. Effect of subinhibitory concentrations of antibiotics on extracellular Shiga-like toxin I. Infection 20, 25-29 (1992).
-
(1992)
Infection
, vol.20
, pp. 25-29
-
-
Walterspiel, J.N.1
Ashkenazi, S.2
Morrow, A.L.3
Cleary, T.G.4
-
100
-
-
0032910242
-
In vitro assessment of a chemically synthesized Shiga toxin receptor analog attached to chromosorb P (Synsorb Pk) as a specific absorbing agent of Shiga toxin 1 and 2
-
Takeda, T., Yoshino, K., Adachi, E., Sato, Y., Yamagata, K. In vitro assessment of a chemically synthesized Shiga toxin receptor analog attached to chromosorb P (Synsorb Pk) as a specific absorbing agent of Shiga toxin 1 and 2. Microbiol. Immunol. 43, 331-337 (1999).
-
(1999)
Microbiol. Immunol.
, vol.43
, pp. 331-337
-
-
Takeda, T.1
Yoshino, K.2
Adachi, E.3
Sato, Y.4
Yamagata, K.5
-
101
-
-
0028947038
-
A phase I study of chemically synthesized verotoxin (Shiga-like toxin) Pk-trisaccharide receptors attached to chromosorb for preventing hemolytic-uremic syndrome
-
Armstrong, G. D., et al. A phase I study of chemically synthesized verotoxin (Shiga-like toxin) Pk-trisaccharide receptors attached to chromosorb for preventing hemolytic-uremic syndrome. J. Infect. Dis. 171, 1042-1045 (1995).
-
(1995)
J. Infect. Dis.
, vol.171
, pp. 1042-1045
-
-
Armstrong, G.D.1
-
102
-
-
0041411080
-
Effect of an oral Shiga toxin-binding agent on diarrhea-associated hemolytic uremic syndrome in children: A randomized controlled trial
-
Trachtman, H., et al. Effect of an oral Shiga toxin-binding agent on diarrhea-associated hemolytic uremic syndrome in children: A randomized controlled trial. JAMA 290, 1337-1344 (2003).
-
(2003)
JAMA
, vol.290
, pp. 1337-1344
-
-
Trachtman, H.1
-
103
-
-
0035884459
-
Efficacy of postinfection treatment with anti-Shiga toxin (Stx) 2 humanized monoclonal antibody TMA-15 in mice lethally challenged with Stx-producing Escherichia coli
-
Yamagami, S., et al. Efficacy of postinfection treatment with anti-Shiga toxin (Stx) 2 humanized monoclonal antibody TMA-15 in mice lethally challenged with Stx-producing Escherichia coli. J. Infect. Dis. 184, 738-742 (2001).
-
(2001)
J. Infect. Dis.
, vol.184
, pp. 738-742
-
-
Yamagami, S.1
-
104
-
-
53649099970
-
Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody
-
Sauter, K. A., et al. Mouse model of hemolytic-uremic syndrome caused by endotoxin-free Shiga toxin 2 (Stx2) and protection from lethal outcome by anti-Stx2 antibody. Infect. Immun. 76, 4469-4478 (2008).
-
(2008)
Infect. Immun.
, vol.76
, pp. 4469-4478
-
-
Sauter, K.A.1
-
105
-
-
73849093228
-
Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli
-
Lopez, E. L., et al. Safety and pharmacokinetics of urtoxazumab, a humanized monoclonal antibody, against Shiga-like toxin 2 in healthy adults and in pediatric patients infected with Shiga-like toxin-producing Escherichia coli. Antimicrob. Agents Chemother. 54, 239-243 (2010).
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 239-243
-
-
Lopez, E.L.1
-
106
-
-
67649960166
-
Safety and pharmacokinetics of chimeric anti-Shiga toxin 1 and anti-Shiga toxin 2 monoclonal antibodies in healthy volunteers
-
Bitzan, M., et al. Safety and pharmacokinetics of chimeric anti-Shiga toxin 1 and anti-Shiga toxin 2 monoclonal antibodies in healthy volunteers. Antimicrob. Agents Chemother. 53, 3081-3087 (2009).
-
(2009)
Antimicrob. Agents Chemother.
, vol.53
, pp. 3081-3087
-
-
Bitzan, M.1
-
107
-
-
84928414071
-
Urinary tract infections: Epidemiology, mechanisms of infection and treatment options
-
Flores-Mireles, A. L., Walker, J. N., Caparon, M., Hultgren, S. J. Urinary tract infections: Epidemiology, mechanisms of infection and treatment options. Nat. Rev. Microbiol. 13, 269-284 (2015).
-
(2015)
Nat. Rev. Microbiol.
, vol.13
, pp. 269-284
-
-
Flores-Mireles, A.L.1
Walker, J.N.2
Caparon, M.3
Hultgren, S.J.4
-
108
-
-
77952569812
-
Bacteremia complicating gram-negative urinary tract infections: A population-based study
-
Al-Hasan, M. N., Eckel-Passow, J. E., Baddour, L. M. Bacteremia complicating gram-negative urinary tract infections: A population-based study. J. Infect. 60, 278-285 (2010).
-
(2010)
J. Infect.
, vol.60
, pp. 278-285
-
-
Al-Hasan, M.N.1
Eckel-Passow, J.E.2
Baddour, L.M.3
-
109
-
-
77953765576
-
Structure-based drug design and optimization of mannoside bacterial FimH antagonists
-
Han, Z., et al. Structure-based drug design and optimization of mannoside bacterial FimH antagonists. J. Med. Chem. 53, 4779-4792 (2010).
-
(2010)
J. Med. Chem.
, vol.53
, pp. 4779-4792
-
-
Han, Z.1
-
110
-
-
84958961158
-
Antivirulence isoquinolone mannosides: Optimization of the biaryl aglycone for FimH lectin binding affinity and efficacy in the treatment of chronic UTI
-
Jarvis, C., et al. Antivirulence isoquinolone mannosides: Optimization of the biaryl aglycone for FimH lectin binding affinity and efficacy in the treatment of chronic UTI. ChemMedChem 11, 367-373 (2016).
-
(2016)
ChemMedChem
, vol.11
, pp. 367-373
-
-
Jarvis, C.1
-
111
-
-
84920895336
-
Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli
-
Greene, S. E., et al. Pilicide ec240 disrupts virulence circuits in uropathogenic Escherichia coli. mBio 5, e02038 (2014).
-
(2014)
MBio
, vol.5
, pp. e02038
-
-
Greene, S.E.1
-
112
-
-
77955370638
-
Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: Pilicides with increased antivirulence activity
-
Chorell, E., et al. Design and synthesis of C-2 substituted thiazolo and dihydrothiazolo ring-fused 2-pyridones: Pilicides with increased antivirulence activity. J. Med. Chem. 53, 5690-5695 (2010).
-
(2010)
J. Med. Chem.
, vol.53
, pp. 5690-5695
-
-
Chorell, E.1
-
113
-
-
81455128775
-
Treatment and prevention of urinary tract infection with orally active FimH inhibitors
-
Cusumano, C. K., et al. Treatment and prevention of urinary tract infection with orally active FimH inhibitors. Sci. Transl Med. 3, 109ra115 (2011).
-
(2011)
Sci. Transl Med.
, vol.3
, pp. 109ra115
-
-
Cusumano, C.K.1
-
114
-
-
84883237676
-
A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131
-
Totsika, M., et al. A FimH inhibitor prevents acute bladder infection and treats chronic cystitis caused by multidrug-resistant uropathogenic Escherichia coli ST131. J. Infect. Dis. 208, 921-928 (2013).
-
(2013)
J. Infect. Dis.
, vol.208
, pp. 921-928
-
-
Totsika, M.1
-
115
-
-
84930354056
-
Inhibition and reversal of microbial attachment by an antibody with parasteric activity against the FimH adhesin of uropathogenic E. Coli
-
Kisiela, D. I., et al. Inhibition and reversal of microbial attachment by an antibody with parasteric activity against the FimH adhesin of uropathogenic E. coli. PLoS Pathog. 11, e1004857 (2015).
-
(2015)
PLoS Pathog.
, vol.11
, pp. e1004857
-
-
Kisiela, D.I.1
-
116
-
-
84978768130
-
Target-agnostic identification of functional monoclonal antibodies against Klebsiella pneumoniae multimeric MrkA fimbrial subunit
-
Wang, Q., et al. Target-agnostic identification of functional monoclonal antibodies against Klebsiella pneumoniae multimeric MrkA fimbrial subunit. J. Infect. Dis. 213, 1800-1808 (2016).
-
(2016)
J. Infect. Dis.
, vol.213
, pp. 1800-1808
-
-
Wang, Q.1
-
117
-
-
34447270735
-
Virulence characteristics of Klebsiella and clinical manifestations of K. Pneumoniae bloodstream infections
-
Yu, V. L., et al. Virulence characteristics of Klebsiella and clinical manifestations of K. pneumoniae bloodstream infections. Emerg. Infect. Dis. 13, 986-993 (2007).
-
(2007)
Emerg. Infect. Dis.
, vol.13
, pp. 986-993
-
-
Yu, V.L.1
-
118
-
-
5644285349
-
High prevalence of phagocytic-resistant capsular serotypes of Klebsiella pneumoniae in liver abscess
-
Lin, J. C., et al. High prevalence of phagocytic-resistant capsular serotypes of Klebsiella pneumoniae in liver abscess. Microbes Infect. 6, 1191-1198 (2004).
-
(2004)
Microbes Infect.
, vol.6
, pp. 1191-1198
-
-
Lin, J.C.1
-
119
-
-
84870946642
-
Antimicrobial-resistant pathogens associated with healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention 2009-2010
-
Sievert, D. M., et al. Antimicrobial-resistant pathogens associated with healthcare-associated infections: Summary of data reported to the National Healthcare Safety Network at the Centers for Disease Control and Prevention, 2009-2010. Infect. Control Hosp. Epidemiol. 34, 1-14 (2013).
-
(2013)
Infect. Control Hosp. Epidemiol.
, vol.34
, pp. 1-14
-
-
Sievert, D.M.1
-
120
-
-
84952871316
-
Rapid dissemination of colistin and carbapenem resistant Acinetobacter baumannii in Central Greece: Mechanisms of resistance, molecular identification and epidemiological data
-
Oikonomou, O., et al. Rapid dissemination of colistin and carbapenem resistant Acinetobacter baumannii in Central Greece: Mechanisms of resistance, molecular identification and epidemiological data. BMC Infect. Dis. 15, 559 (2015).
-
(2015)
BMC Infect. Dis.
, vol.15
, pp. 559
-
-
Oikonomou, O.1
-
121
-
-
84928902817
-
Colistin-resistant Acinetobacter baumannii: Beyond carbapenem resistance
-
Qureshi, Z. A., et al. Colistin-resistant Acinetobacter baumannii: Beyond carbapenem resistance. Clin. Infect. Dis. 60, 1295-1303 (2015).
-
(2015)
Clin. Infect. Dis.
, vol.60
, pp. 1295-1303
-
-
Qureshi, Z.A.1
-
122
-
-
84941561450
-
Molecular identification of tigecycline-and colistin-resistant carbapenemase-producing Acinetobacter baumannii from a Greek hospital from 2011 to 2013
-
Mavroidi, A., et al. Molecular identification of tigecycline-and colistin-resistant carbapenemase-producing Acinetobacter baumannii from a Greek hospital from 2011 to 2013. J. Med. Microbiol. 64, 993-997 (2015).
-
(2015)
J. Med. Microbiol.
, vol.64
, pp. 993-997
-
-
Mavroidi, A.1
-
123
-
-
85022137968
-
-
European Antimicrobial Resistance Surveillance Network. Antimicrobial resistance surveillance in Europe. EARS-Net
-
European Antimicrobial Resistance Surveillance Network. Antimicrobial resistance surveillance in Europe. http://ecdc. europa. eu/en/publications/publications/antimicrobial-resistance-europe-2014. pdf (EARS-Net, 2014).
-
(2014)
-
-
-
124
-
-
84868352677
-
Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis
-
Lin, L., et al. Inhibition of LpxC protects mice from resistant Acinetobacter baumannii by modulating inflammation and enhancing phagocytosis. mBio 3, e00312-12 (2012).
-
(2012)
MBio
, vol.3
, pp. e00312-e00412
-
-
Lin, L.1
-
125
-
-
78649650250
-
Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production
-
Moffatt, J. H., et al. Colistin resistance in Acinetobacter baumannii is mediated by complete loss of lipopolysaccharide production. Antimicrob. Agents Chemother. 54, 4971-4977 (2010).
-
(2010)
Antimicrob. Agents Chemother.
, vol.54
, pp. 4971-4977
-
-
Moffatt, J.H.1
-
126
-
-
84979284304
-
Inhibition of LpxC increases antibiotic susceptibility in Acinetobacter baumannii
-
Garcia-Quintanilla, M., et al. Inhibition of LpxC increases antibiotic susceptibility in Acinetobacter baumannii. Antimicrob. Agents Chemother. 60, 5076-5079 (2016).
-
(2016)
Antimicrob. Agents Chemother.
, vol.60
, pp. 5076-5079
-
-
Garcia-Quintanilla, M.1
-
127
-
-
42549124678
-
Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii
-
Niu, C., Clemmer, K. M., Bonomo, R. A., Rather, P. N. Isolation and characterization of an autoinducer synthase from Acinetobacter baumannii. J. Bacteriol. 190, 3386-3392 (2008).
-
(2008)
J. Bacteriol.
, vol.190
, pp. 3386-3392
-
-
Niu, C.1
Clemmer, K.M.2
Bonomo, R.A.3
Rather, P.N.4
-
128
-
-
77958050359
-
Quorum sensing in Acinetobacter: An emerging pathogen
-
Bhargava, N., Sharma, P., Capalash, N. Quorum sensing in Acinetobacter: An emerging pathogen. Crit. Rev. Microbiol. 36, 349-360 (2010).
-
(2010)
Crit. Rev. Microbiol.
, vol.36
, pp. 349-360
-
-
Bhargava, N.1
Sharma, P.2
Capalash, N.3
-
129
-
-
84867770740
-
Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-Acyl homoserine lactones
-
Stacy, D. M., Welsh, M. A., Rather, P. N., Blackwell, H. E. Attenuation of quorum sensing in the pathogen Acinetobacter baumannii using non-native N-Acyl homoserine lactones. ACS Chem. Biol. 7, 1719-1728 (2012).
-
(2012)
ACS Chem. Biol.
, vol.7
, pp. 1719-1728
-
-
Stacy, D.M.1
Welsh, M.A.2
Rather, P.N.3
Blackwell, H.E.4
-
130
-
-
27344443267
-
Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization
-
Hung, D. T., Shakhnovich, E. A., Pierson, E., Mekalanos, J. J. Small-molecule inhibitor of Vibrio cholerae virulence and intestinal colonization. Science 310, 670-674 (2005).
-
(2005)
Science
, vol.310
, pp. 670-674
-
-
Hung, D.T.1
Shakhnovich, E.A.2
Pierson, E.3
Mekalanos, J.J.4
-
131
-
-
84899129806
-
Virstatin inhibits biofilm formation and motility of Acinetobacter baumannii
-
Nait Chabane, Y., et al. Virstatin inhibits biofilm formation and motility of Acinetobacter baumannii. BMC Microbiol. 14, 62 (2014).
-
(2014)
BMC Microbiol.
, vol.14
, pp. 62
-
-
Nait Chabane, Y.1
-
132
-
-
84940202835
-
Role of LuxIR homologue AnoIR in Acinetobacter nosocomialis and the effect of virstatin on the expression of anoR gene
-
Oh, M. H., Choi, C. H. Role of LuxIR homologue AnoIR in Acinetobacter nosocomialis and the effect of virstatin on the expression of anoR gene. J. Microbiol. Biotechnol. 25, 1390-1400 (2015).
-
(2015)
J. Microbiol. Biotechnol.
, vol.25
, pp. 1390-1400
-
-
Oh, M.H.1
Choi, C.H.2
-
133
-
-
84866334623
-
Antibacterial activities of iron chelators against common nosocomial pathogens
-
Thompson, M. G., Corey, B. W., Si, Y., Craft, D. W., Zurawski, D. V. Antibacterial activities of iron chelators against common nosocomial pathogens. Antimicrob. Agents Chemother. 56, 5419-5421 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 5419-5421
-
-
Thompson, M.G.1
Corey, B.W.2
Si, Y.3
Craft, D.W.4
Zurawski, D.V.5
-
134
-
-
84866326661
-
In vitro and in vivo biological activities of iron chelators and gallium nitrate against Acinetobacter baumannii
-
de Leseleuc, L., Harris, G., KuoLee, R., Chen, W. In vitro and in vivo biological activities of iron chelators and gallium nitrate against Acinetobacter baumannii. Antimicrob. Agents Chemother. 56, 5397-5400 (2012).
-
(2012)
Antimicrob. Agents Chemother.
, vol.56
, pp. 5397-5400
-
-
De Leseleuc, L.1
Harris, G.2
KuoLee, R.3
Chen, W.4
-
135
-
-
84903956916
-
Genome-wide identification of Acinetobacter baumannii genes necessary for persistence in the lung
-
Wang, N., Ozer, E. A., Mandel, M. J., Hauser, A. R. Genome-wide identification of Acinetobacter baumannii genes necessary for persistence in the lung. mBio 5, e01163-14 (2014).
-
(2014)
MBio
, vol.5
, pp. e01163-e01214
-
-
Wang, N.1
Ozer, E.A.2
Mandel, M.J.3
Hauser, A.R.4
-
136
-
-
84969381698
-
Acinetobacter baumannii genes required for bacterial survival during bloodstream infection
-
Subashchandrabose, S., et al. Acinetobacter baumannii genes required for bacterial survival during bloodstream infection. mSphere 1, e00013-15 (2016).
-
(2016)
MSphere
, vol.1
, pp. e00013
-
-
Subashchandrabose, S.1
-
137
-
-
84960409046
-
Pathogenic Acinetobacter: From the cell surface to infinity and beyond
-
Weber, B. S., Harding, C. M., Feldman, M. F. Pathogenic Acinetobacter: From the cell surface to infinity and beyond. J. Bacteriol. 198, 880-887 (2016).
-
(2016)
J. Bacteriol.
, vol.198
, pp. 880-887
-
-
Weber, B.S.1
Harding, C.M.2
Feldman, M.F.3
-
138
-
-
84995576444
-
Antibody-based therapy for Enterococcal catheter-associated urinary tract infections
-
Flores-Mireles, A. L., et al. Antibody-based therapy for Enterococcal catheter-associated urinary tract infections. mBio 7, e01653-16 (2016).
-
(2016)
MBio
, vol.7
, pp. e01653-e01716
-
-
Flores-Mireles, A.L.1
-
139
-
-
84877024304
-
Structure function, biology of the Enterococcus faecalis cytolysin
-
Van Tyne, D., Martin, M. J., Gilmore, M. S. Structure, function, biology of the Enterococcus faecalis cytolysin. Toxins (Basel) 5, 895-911 (2013).
-
(2013)
Toxins (Basel)
, vol.5
, pp. 895-911
-
-
Van Tyne, D.1
Martin, M.J.2
Gilmore, M.S.3
-
140
-
-
0025985759
-
Bacteremia caused by hemolytic, high-level gentamicin-resistant Enterococcus faecalis
-
Huycke, M. M., Spiegel, C. A., Gilmore, M. S. Bacteremia caused by hemolytic, high-level gentamicin-resistant Enterococcus faecalis. Antimicrob. Agents Chemother. 35, 1626-1634 (1991).
-
(1991)
Antimicrob. Agents Chemother.
, vol.35
, pp. 1626-1634
-
-
Huycke, M.M.1
Spiegel, C.A.2
Gilmore, M.S.3
-
141
-
-
84948787940
-
Cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in Gram-positive bacteria
-
Desouky, S. E., et al. Cyclodepsipeptides produced by actinomycetes inhibit cyclic-peptide-mediated quorum sensing in Gram-positive bacteria. FEMS Microbiol. Lett. 362, fnv109 (2015).
-
(2015)
FEMS Microbiol. Lett.
, vol.362
, pp. 109
-
-
Desouky, S.E.1
-
142
-
-
84876555441
-
Development of a peptide antagonist against fsr quorum sensing of Enterococcus faecalis
-
Nakayama, J., et al. Development of a peptide antagonist against fsr quorum sensing of Enterococcus faecalis. ACS Chem. Biol. 8, 804-811 (2013).
-
(2013)
ACS Chem. Biol.
, vol.8
, pp. 804-811
-
-
Nakayama, J.1
-
143
-
-
33846940902
-
Siamycin attenuates fsr quorum sensing mediated by a gelatinase biosynthesis-activating pheromone in Enterococcus faecalis
-
Nakayama, J., et al. Siamycin attenuates fsr quorum sensing mediated by a gelatinase biosynthesis-activating pheromone in Enterococcus faecalis. J. Bacteriol. 189, 1358-1365 (2007).
-
(2007)
J. Bacteriol.
, vol.189
, pp. 1358-1365
-
-
Nakayama, J.1
-
144
-
-
0017198484
-
Partial purification and properties of Enterobacter cloacae heat-stable enterotoxin
-
Klipstein, F. A., Engert, R. F. Partial purification and properties of Enterobacter cloacae heat-stable enterotoxin. Infect. Immun. 13, 1307-1314 (1976).
-
(1976)
Infect. Immun.
, vol.13
, pp. 1307-1314
-
-
Klipstein, F.A.1
Engert, R.F.2
-
145
-
-
0035657681
-
Molecular properties and metabolic effect on blood cells produced by a new toxin of Enterobacter cloacae
-
Barnes, A. I., Paraje, M. G., Battan, P. del C., Albesa, I. Molecular properties and metabolic effect on blood cells produced by a new toxin of Enterobacter cloacae. Cell Biol. Toxicol. 17, 409-418 (2001)
-
(2001)
Cell Biol. Toxicol.
, vol.17
, pp. 409-418
-
-
Barnes, A.I.1
Paraje, M.G.2
Battan Del P, C.3
Albesa, I.4
-
146
-
-
0030842805
-
Purification and characterization of a cytotoxin from Enterobacter cloacae
-
Barnes, A. I., Ortiz, C., Paraje, M. G., Balanzino, L. E., Albesa, I. Purification and characterization of a cytotoxin from Enterobacter cloacae. Can. J. Microbiol. 43, 729-733 (1997).
-
(1997)
Can. J. Microbiol.
, vol.43
, pp. 729-733
-
-
Barnes, A.I.1
Ortiz, C.2
Paraje, M.G.3
Balanzino, L.E.4
Albesa, I.5
-
147
-
-
0030027297
-
Enterobacter cloacae producing a Shiga-like toxin II-related cytotoxin associated with a case of hemolytic-uremic syndrome
-
Paton, A. W., Paton, J. C. Enterobacter cloacae producing a Shiga-like toxin II-related cytotoxin associated with a case of hemolytic-uremic syndrome. J. Clin. Microbiol. 34, 463-465 (1996).
-
(1996)
J. Clin. Microbiol.
, vol.34
, pp. 463-465
-
-
Paton, A.W.1
Paton, J.C.2
-
148
-
-
84903756809
-
Isolation and identification of an Enterobacter cloacae strain producing a novel subtype of Shiga toxin type 1
-
Probert, W. S., McQuaid, C., Schrader, K. Isolation and identification of an Enterobacter cloacae strain producing a novel subtype of Shiga toxin type 1. J. Clin. Microbiol. 52, 2346-2351 (2014).
-
(2014)
J. Clin. Microbiol.
, vol.52
, pp. 2346-2351
-
-
Probert, W.S.1
McQuaid, C.2
Schrader, K.3
-
149
-
-
4644358200
-
Shiga toxin-encoding bacteriophages-genomes in motion
-
Herold, S., Karch, H., Schmidt, H. Shiga toxin-encoding bacteriophages-genomes in motion. Int. J. Med. Microbiol. 294, 115-121 (2004).
-
(2004)
Int. J. Med. Microbiol.
, vol.294
, pp. 115-121
-
-
Herold, S.1
Karch, H.2
Schmidt, H.3
-
150
-
-
84979562950
-
Phage-mediated Shiga toxin (Stx) horizontal gene transfer and expression in non-Shiga toxigenic Enterobacter and Escherichia coli strains
-
Khalil, R. K., Skinner, C., Patfield, S., He, X. Phage-mediated Shiga toxin (Stx) horizontal gene transfer and expression in non-Shiga toxigenic Enterobacter and Escherichia coli strains. Pathog. Dis. 74, ftw037 (2016).
-
(2016)
Pathog. Dis.
, vol.74
, pp. 37
-
-
Khalil, R.K.1
Skinner, C.2
Patfield, S.3
He, X.4
-
151
-
-
0020265072
-
Siderophore production by Enterobacter cloacae and a common receptor protein for the uptake of aerobactin and cloacin DF13
-
Van Tiel-Menkveld, G. J., Mentjox-Vervuurt, J. M., Oudega, B., de Graaf, F. K. Siderophore production by Enterobacter cloacae and a common receptor protein for the uptake of aerobactin and cloacin DF13. J. Bacteriol. 150, 490-497 (1982).
-
(1982)
J. Bacteriol.
, vol.150
, pp. 490-497
-
-
Van Tiel-Menkveld, G.J.1
Mentjox-Vervuurt, J.M.2
Oudega, B.3
De Graaf, F.K.4
-
152
-
-
84863282007
-
Involvement of curli fimbriae in the biofilm formation of Enterobacter cloacae
-
Kim, S. M., et al. Involvement of curli fimbriae in the biofilm formation of Enterobacter cloacae. J. Microbiol. 50, 175-178 (2012).
-
(2012)
J. Microbiol.
, vol.50
, pp. 175-178
-
-
Kim, S.M.1
-
153
-
-
0038309658
-
Production of cellulose and curli fimbriae by members of the family Enterobacteriaceae isolated from the human gastrointestinal tract
-
Zogaj, X., Bokranz, W., Nimtz, M., Romling, U. Production of cellulose and curli fimbriae by members of the family Enterobacteriaceae isolated from the human gastrointestinal tract. Infect. Immun. 71, 4151-4158 (2003).
-
(2003)
Infect. Immun.
, vol.71
, pp. 4151-4158
-
-
Zogaj, X.1
Bokranz, W.2
Nimtz, M.3
Romling, U.4
-
154
-
-
67650723300
-
Cytotoxic activity of Enterobacter cloacae human isolates
-
Krzyminska, S., Mokracka, J., Koczura, R., Kaznowski, A. Cytotoxic activity of Enterobacter cloacae human isolates. FEMS Immunol. Med. Microbiol. 56, 248-252 (2009).
-
(2009)
FEMS Immunol. Med. Microbiol.
, vol.56
, pp. 248-252
-
-
Krzyminska, S.1
Mokracka, J.2
Koczura, R.3
Kaznowski, A.4
-
155
-
-
84861566881
-
Detection of AI-2 receptors in genomes of Enterobacteriaceae suggests a role of type-2 quorum sensing in closed ecosystems
-
Rezzonico, F., Smits, T. H., Duffy, B. Detection of AI-2 receptors in genomes of Enterobacteriaceae suggests a role of type-2 quorum sensing in closed ecosystems. Sensors (Basel) 12, 6645-6665 (2012).
-
(2012)
Sensors (Basel)
, vol.12
, pp. 6645-6665
-
-
Rezzonico, F.1
Smits, T.H.2
Duffy, B.3
-
156
-
-
85019080246
-
New monoclonal antibodies against a novel subtype of Shiga toxin 1 produced by Enterobacter cloacae and their use in analysis of human serum
-
Skinner, C., Patfield, S., Khalil, R., Kong, Q., He, X. New monoclonal antibodies against a novel subtype of Shiga toxin 1 produced by Enterobacter cloacae and their use in analysis of human serum. mSphere 1, e00099-15 (2016).
-
(2016)
MSphere
, vol.1
, pp. e00099-e00115
-
-
Skinner, C.1
Patfield, S.2
Khalil, R.3
Kong, Q.4
He, X.5
-
157
-
-
84935892144
-
-
World Health Organization WHO
-
World Health Organization. Global Tuberculosis Report 2015. http://apps. who. int/iris/bitstream/10665/191102/1/9789241565059-eng. pdfua=1 (WHO, 2015).
-
(2015)
Global Tuberculosis Report 2015
-
-
-
158
-
-
84897959389
-
Progress in tuberculosis vaccine development and host-directed therapies-a state of the art review
-
Kaufmann, S. H., et al. Progress in tuberculosis vaccine development and host-directed therapies-a state of the art review. Lancet Respir. Med. 2, 301-320 (2014).
-
(2014)
Lancet Respir. Med.
, vol.2
, pp. 301-320
-
-
Kaufmann, S.H.1
-
159
-
-
0028153628
-
Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature
-
Colditz, G. A., et al. Efficacy of BCG vaccine in the prevention of tuberculosis. Meta-analysis of the published literature. JAMA 271, 698-702 (1994).
-
(1994)
JAMA
, vol.271
, pp. 698-702
-
-
Colditz, G.A.1
-
160
-
-
0037312505
-
Lipoarabinomannan-reactive human secretory immunoglobulin A responses induced by mucosal bacille Calmette-Guerin vaccination
-
Brown, R. M., et al. Lipoarabinomannan-reactive human secretory immunoglobulin A responses induced by mucosal bacille Calmette-Guerin vaccination. J. Infect. Dis. 187, 513-517 (2003).
-
(2003)
J. Infect. Dis.
, vol.187
, pp. 513-517
-
-
Brown, R.M.1
-
161
-
-
0029057936
-
Humoral immune response in infants after BCG vaccination
-
Beyazova, U., Rota, S., Cevheroglu, C., Karsligil, T. Humoral immune response in infants after BCG vaccination. Tuber. Lung Dis. 76, 248-253 (1995).
-
(1995)
Tuber. Lung Dis.
, vol.76
, pp. 248-253
-
-
Beyazova, U.1
Rota, S.2
Cevheroglu, C.3
Karsligil, T.4
-
162
-
-
59649121314
-
Performance of purified antigens for serodiagnosis of pulmonary tuberculosis: A meta-analysis
-
Steingart, K. R., et al. Performance of purified antigens for serodiagnosis of pulmonary tuberculosis: A meta-analysis. Clin. Vaccine Immunol. 16, 260-276 (2009).
-
(2009)
Clin. Vaccine Immunol.
, vol.16
, pp. 260-276
-
-
Steingart, K.R.1
-
163
-
-
0037417012
-
Mycobacterium tuberculosis in the extracellular compartment: An underestimated adversary
-
Grosset, J. Mycobacterium tuberculosis in the extracellular compartment: An underestimated adversary. Antimicrob. Agents Chemother. 47, 833-836 (2003).
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 833-836
-
-
Grosset, J.1
-
164
-
-
0031812585
-
Characterization of mannose receptor-dependent phagocytosis mediated by Mycobacterium tuberculosis lipoarabinomannan
-
Kang, B. K., Schlesinger, L. S. Characterization of mannose receptor-dependent phagocytosis mediated by Mycobacterium tuberculosis lipoarabinomannan. Infect. Immun. 66, 2769-2777 (1998).
-
(1998)
Infect. Immun.
, vol.66
, pp. 2769-2777
-
-
Kang, B.K.1
Schlesinger, L.S.2
-
165
-
-
0029838994
-
Identification of a heparin-binding hemagglutinin present in mycobacteria
-
Menozzi, F. D., et al. Identification of a heparin-binding hemagglutinin present in mycobacteria. J. Exp. Med. 184, 993-1001 (1996).
-
(1996)
J. Exp. Med.
, vol.184
, pp. 993-1001
-
-
Menozzi, F.D.1
-
166
-
-
0029785912
-
Stationary phase-associated protein expression in Mycobacterium tuberculosis: Function of the mycobacterial alpha-crystallin homolog
-
Yuan, Y., Crane, D. D., Barry, C. E. III. Stationary phase-associated protein expression in Mycobacterium tuberculosis: Function of the mycobacterial alpha-crystallin homolog. J. Bacteriol. 178, 4484-4492 (1996).
-
(1996)
J. Bacteriol.
, vol.178
, pp. 4484-4492
-
-
Yuan, Y.1
Crane, D.D.2
Barry, C.E.3
-
167
-
-
4644312486
-
A mycobacterial lipoarabinomannan specific monoclonal antibody and its F(ab') fragment prolong survival of mice infected with Mycobacterium tuberculosis
-
Hamasur, B., et al. A mycobacterial lipoarabinomannan specific monoclonal antibody and its F(ab') fragment prolong survival of mice infected with Mycobacterium tuberculosis. Clin. Exp. Immunol. 138, 30-38 (2004).
-
(2004)
Clin. Exp. Immunol.
, vol.138
, pp. 30-38
-
-
Hamasur, B.1
-
168
-
-
79952759532
-
A novel human IgA monoclonal antibody protects against tuberculosis
-
Balu, S., et al. A novel human IgA monoclonal antibody protects against tuberculosis. J. Immunol. 186, 3113-3119 (2011).
-
(2011)
J. Immunol.
, vol.186
, pp. 3113-3119
-
-
Balu, S.1
-
169
-
-
0035849873
-
The heparin-binding haemagglutinin of M. Tuberculosis is required for extrapulmonary dissemination
-
Pethe, K., et al. The heparin-binding haemagglutinin of M. tuberculosis is required for extrapulmonary dissemination. Nature 412, 190-194 (2001).
-
(2001)
Nature
, vol.412
, pp. 190-194
-
-
Pethe, K.1
-
170
-
-
84941022425
-
The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD
-
Sun, J., et al. The tuberculosis necrotizing toxin kills macrophages by hydrolyzing NAD. Nat. Struct. Mol. Biol. 22, 672-678 (2015).
-
(2015)
Nat. Struct. Mol. Biol.
, vol.22
, pp. 672-678
-
-
Sun, J.1
-
171
-
-
84988689965
-
ESX secretion systems: Mycobacterial evolution to counter host immunity
-
Groschel, M. I., Sayes, F., Simeone, R., Majlessi, L., Brosch, R. ESX secretion systems: Mycobacterial evolution to counter host immunity. Nat. Rev. Microbiol. 14, 677-691 (2016).
-
(2016)
Nat. Rev. Microbiol.
, vol.14
, pp. 677-691
-
-
Groschel, M.I.1
Sayes, F.2
Simeone, R.3
Majlessi, L.4
Brosch, R.5
-
172
-
-
57749107808
-
Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America
-
Boucher, H. W., et al. Bad bugs, no drugs: No ESKAPE! An update from the Infectious Diseases Society of America. Clin. Infect. Dis. 48, 1-12 (2009).
-
(2009)
Clin. Infect. Dis.
, vol.48
, pp. 1-12
-
-
Boucher, H.W.1
-
173
-
-
27944442272
-
Quorum sensing: Cell-to-cell communication in bacteria
-
Waters, C. M., Bassler, B. L. Quorum sensing: Cell-to-cell communication in bacteria. Annu. Rev. Cell Dev. Biol. 21, 319-346 (2005).
-
(2005)
Annu. Rev. Cell Dev. Biol.
, vol.21
, pp. 319-346
-
-
Waters, C.M.1
Bassler, B.L.2
-
174
-
-
84982121502
-
Quorum sensing signal-response systems in Gram-negative bacteria
-
Papenfort, K., Bassler, B. L. Quorum sensing signal-response systems in Gram-negative bacteria. Nat. Rev. Microbiol. 14, 576-588 (2016).
-
(2016)
Nat. Rev. Microbiol.
, vol.14
, pp. 576-588
-
-
Papenfort, K.1
Bassler, B.L.2
-
175
-
-
84875597802
-
Bacterial quorum sensing: Its role in virulence and possibilities for its control
-
Rutherford, S. T., Bassler, B. L. Bacterial quorum sensing: Its role in virulence and possibilities for its control. Cold Spring Harb. Perspect. Med. 2, a012427 (2012).
-
(2012)
Cold Spring Harb. Perspect. Med.
, vol.2
, pp. a012427
-
-
Rutherford, S.T.1
Bassler, B.L.2
-
176
-
-
33644871220
-
Staphylococcus quorum sensing in biofilm formation and infection
-
Kong, K. F., Vuong, C., Otto, M. Staphylococcus quorum sensing in biofilm formation and infection. Int. J. Med. Microbiol. 296, 133-139 (2006).
-
(2006)
Int. J. Med. Microbiol.
, vol.296
, pp. 133-139
-
-
Kong, K.F.1
Vuong, C.2
Otto, M.3
-
177
-
-
4444346026
-
Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein
-
Fowler, V. G. Jr, et al. Persistent bacteremia due to methicillin-resistant Staphylococcus aureus infection is associated with agr dysfunction and low-level in vitro resistance to thrombin-induced platelet microbicidal protein. J. Infect. Dis. 190, 1140-1149 (2004).
-
(2004)
J. Infect. Dis.
, vol.190
, pp. 1140-1149
-
-
Fowler, V.G.1
-
178
-
-
84930260701
-
Can resistance against quorum-sensing interference be selected
-
Garcia-Contreras, R., Maeda, T., Wood, T. K. Can resistance against quorum-sensing interference be selected ISME J. 10, 4-10 (2016).
-
(2016)
ISME J
, vol.10
, pp. 4-10
-
-
Garcia-Contreras, R.1
Maeda, T.2
Wood, T.K.3
-
179
-
-
84908180998
-
Competition studies confirm two major barriers that can preclude the spread of resistance to quorum-sensing inhibitors in bacteria
-
Gerdt, J. P., Blackwell, H. E. Competition studies confirm two major barriers that can preclude the spread of resistance to quorum-sensing inhibitors in bacteria. ACS Chem. Biol. 9, 2291-2299 (2014).
-
(2014)
ACS Chem. Biol.
, vol.9
, pp. 2291-2299
-
-
Gerdt, J.P.1
Blackwell, H.E.2
-
180
-
-
80455130021
-
The sociomicrobiology of antivirulence drug resistance: A proof of concept
-
Mellbye, B., Schuster, M. The sociomicrobiology of antivirulence drug resistance: A proof of concept. mBio 2, e00131-11 (2011).
-
(2011)
MBio
, vol.2
, pp. e00131-e00211
-
-
Mellbye, B.1
Schuster, M.2
-
181
-
-
74049105641
-
Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria
-
Carnes, E. C., et al. Confinement-induced quorum sensing of individual Staphylococcus aureus bacteria. Nat. Chem. Biol. 6, 41-45 (2010).
-
(2010)
Nat. Chem. Biol.
, vol.6
, pp. 41-45
-
-
Carnes, E.C.1
-
182
-
-
84857124144
-
Quorum quenching quandary: Resistance to antivirulence compounds
-
Maeda, T., et al. Quorum quenching quandary: Resistance to antivirulence compounds. ISME J. 6, 493-501 (2012).
-
(2012)
ISME J.
, vol.6
, pp. 493-501
-
-
Maeda, T.1
-
183
-
-
0036229278
-
Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover
-
Manefield, M., et al. Halogenated furanones inhibit quorum sensing through accelerated LuxR turnover. Microbiology 148, 1119-1127 (2002).
-
(2002)
Microbiology
, vol.148
, pp. 1119-1127
-
-
Manefield, M.1
-
184
-
-
33750493617
-
Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters
-
Babcock, G. J., et al. Human monoclonal antibodies directed against toxins A and B prevent Clostridium difficile-induced mortality in hamsters. Infect. Immun. 74, 6339-6347 (2006).
-
(2006)
Infect. Immun.
, vol.74
, pp. 6339-6347
-
-
Babcock, G.J.1
-
185
-
-
33644959711
-
Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing
-
Kaufmann, G. F., et al. Antibody interference with N-acyl homoserine lactone-mediated bacterial quorum sensing. J. Am. Chem. Soc. 128, 2802-2803 (2006).
-
(2006)
J. Am. Chem. Soc.
, vol.128
, pp. 2802-2803
-
-
Kaufmann, G.F.1
-
186
-
-
62449123361
-
An engineered human antibody fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent antibacterial activity
-
Baer, M., et al. An engineered human antibody fab fragment specific for Pseudomonas aeruginosa PcrV antigen has potent antibacterial activity. Infect. Immun. 77, 1083-1090 (2009).
-
(2009)
Infect. Immun.
, vol.77
, pp. 1083-1090
-
-
Baer, M.1
-
187
-
-
84994149342
-
Inhibition of the injectisome and flagellar type III secretion systems by INP1855 impairs Pseudomonas aeruginosa pathogenicity and inflammasome activation
-
Anantharajah, A., et al. Inhibition of the injectisome and flagellar type III secretion systems by INP1855 impairs Pseudomonas aeruginosa pathogenicity and inflammasome activation. J. Infect. Dis. 214, 1105-1116 (2016).
-
(2016)
J. Infect. Dis.
, vol.214
, pp. 1105-1116
-
-
Anantharajah, A.1
-
188
-
-
84923090939
-
Synthesis and structure-activity relationships of novel phenoxyacetamide inhibitors of the Pseudomonas aeruginosa type III secretion system (T3SS)
-
Williams, J. D., et al. Synthesis and structure-activity relationships of novel phenoxyacetamide inhibitors of the Pseudomonas aeruginosa type III secretion system (T3SS). Bioorg. Med. Chem. 23, 1027-1043 (2015).
-
(2015)
Bioorg. Med. Chem.
, vol.23
, pp. 1027-1043
-
-
Williams, J.D.1
-
189
-
-
84896983589
-
Mutations in the Pseudomonas aeruginosa needle protein gene pscF confer resistance to phenoxyacetamide inhibitors of the type III secretion system
-
Bowlin, N. O., et al. Mutations in the Pseudomonas aeruginosa needle protein gene pscF confer resistance to phenoxyacetamide inhibitors of the type III secretion system. Antimicrob. Agents Chemother. 58, 2211-2220 (2014).
-
(2014)
Antimicrob. Agents Chemother.
, vol.58
, pp. 2211-2220
-
-
Bowlin, N.O.1
-
190
-
-
84945189887
-
Potent and selective modulation of the RhlR quorum sensing receptor by using non-native ligands: An emerging target for virulence control in Pseudomonas aeruginosa
-
Eibergen, N. R., Moore, J. D., Mattmann, M. E., Blackwell, H. E. Potent and selective modulation of the RhlR quorum sensing receptor by using non-native ligands: An emerging target for virulence control in Pseudomonas aeruginosa. Chembiochem 16, 2348-2356 (2015).
-
(2015)
Chembiochem
, vol.16
, pp. 2348-2356
-
-
Eibergen, N.R.1
Moore, J.D.2
Mattmann, M.E.3
Blackwell, H.E.4
-
191
-
-
84887034499
-
A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation
-
O'Loughlin, C. T., et al. A quorum-sensing inhibitor blocks Pseudomonas aeruginosa virulence and biofilm formation. Proc. Natl Acad. Sci. USA 110, 17981-17986 (2013).
-
(2013)
Proc. Natl Acad. Sci. USA
, vol.110
, pp. 17981-17986
-
-
O'Loughlin, C.T.1
-
192
-
-
68049115757
-
Covalent inhibition of bacterial quorum sensing
-
Amara, N., et al. Covalent inhibition of bacterial quorum sensing. J. Am. Chem. Soc. 131, 10610-10619 (2009).
-
(2009)
J. Am. Chem. Soc.
, vol.131
, pp. 10610-10619
-
-
Amara, N.1
-
193
-
-
0041989633
-
Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors
-
Hentzer, M., et al. Attenuation of Pseudomonas aeruginosa virulence by quorum sensing inhibitors. EMBO J. 22, 3803-3815 (2003).
-
(2003)
EMBO J.
, vol.22
, pp. 3803-3815
-
-
Hentzer, M.1
-
194
-
-
3042597309
-
Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice
-
Wu, H., et al. Synthetic furanones inhibit quorum-sensing and enhance bacterial clearance in Pseudomonas aeruginosa lung infection in mice. J. Antimicrob. Chemother. 53, 1054-1061 (2004).
-
(2004)
J. Antimicrob. Chemother.
, vol.53
, pp. 1054-1061
-
-
Wu, H.1
-
195
-
-
0037256665
-
Induction and inhibition of Pseudomonas aeruginosa quorum sensing by synthetic autoinducer analogs
-
Smith, K. M., Bu, Y., Suga, H. Induction and inhibition of Pseudomonas aeruginosa quorum sensing by synthetic autoinducer analogs. Chem. Biol. 10, 81-89 (2003).
-
(2003)
Chem. Biol.
, vol.10
, pp. 81-89
-
-
Smith, K.M.1
Bu, Y.2
Suga, H.3
|