Expression of SREBP-1c requires SREBP-2-mediated generation of a sterol ligand for LXR in livers of mice

eLife

Volumn 6, Issue , 2017, Pages

  Rong, Shunxing ^a   Cortés, Víctor A ^a,b   Rashid, Shirya ^a,c   Anderson, Norma N ^a   McDonald, Jeffrey G ^a   Liang, Guosheng ^a   Moon, Young Ah ^a,d   Hammer, Robert E ^a   Horton, Jay D ^a  

^a UNIVERSITY OF TEXAS SOUTHWESTERN MEDICAL CENTER   (United States)

^b PONTIFICIA UNIVERSIDAD CATÓLICA DE CHILE   (Chile)

^c NORTH SOUTH UNIVERSITY   (Bangladesh)

^d Inha University School of Medicine   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

STEROL REGULATORY ELEMENT BINDING PROTEIN 1C; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; CHOLESTEROL; FATTY ACID; LIVER X RECEPTOR; SREBF1 PROTEIN, MOUSE; SREBF2 PROTEIN, MOUSE; STEROL REGULATORY ELEMENT BINDING PROTEIN 1;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL DISRUPTION; CHOLESTEROL SYNTHESIS; CONTROLLED STUDY; FATTY ACID SYNTHESIS; GENE DELETION; GENE EXPRESSION; GENE TARGETING; GENOTYPE; IMMUNOBLOTTING; MALE; MOUSE; NONHUMAN; PLASMA CLEARANCE; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION REGULATION; ANIMAL; BIOSYNTHESIS; GENE EXPRESSION REGULATION; GENE INACTIVATION; GENETIC TRANSCRIPTION; GENETICS; KNOCKOUT MOUSE; LIVER; METABOLISM; PHYSIOLOGY;

ANIMALS; CHOLESTEROL; FATTY ACIDS; GENE EXPRESSION REGULATION; GENE KNOCKOUT TECHNIQUES; LIVER; LIVER X RECEPTORS; MICE; MICE, KNOCKOUT; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; STEROL REGULATORY ELEMENT BINDING PROTEIN 2; TRANSCRIPTION, GENETIC;

EID: 85015326922     PISSN: None     EISSN: 2050084X     Source Type: Journal    
DOI: 10.7554/eLife.25015     Document Type: Article

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