CRISPR-Cas9-mediated gene knockout in primary human airway epithelial cells reveals a proinflammatory role for MUC18

Gene Therapy

Volumn 22, Issue 10, 2015, Pages 822-829

  Chu, H W ^a   Rios, C ^a   Huang, C ^a   Wesolowska Andersen, A ^a   Burchard, E G ^b,c   O'Connor, B P ^a   Fingerlin, T E ^a   Nichols, D ^a   Reynolds, S D ^a   Seibold, M A ^a,d  

^a DEPARTMENT OF MEDICINE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d UNIVERSITY OF COLORADO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD146 ANTIGEN; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROME REPEATS ASSOCIATED CAS9 NUCLEASE; INTERLEUKIN 8; LENTIVIRUS VECTOR; NUCLEASE; PUROMYCIN; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; MCAM PROTEIN, HUMAN;

AMPLICON; ANIMAL CELL; ARTICLE; CELL POPULATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DNA BASE COMPOSITION; EPITHELIUM CELL; EXON; GENE EXPRESSION; GENE INACTIVATION; HIGH RESOLUTION MELTING ANALYSIS; HUMAN; HUMAN CELL; INDEL MUTATION; LUNG ALVEOLUS MACROPHAGE; MOUSE; NASAL AIRWAY EPITHELIAL CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; VIRAL GENE DELIVERY SYSTEM; WESTERN BLOTTING; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEAT; GENE VECTOR; GENETICS; IMMUNOLOGY; INFLAMMATION; LENTIVIRINAE; METABOLISM; PRIMARY CELL CULTURE; RESPIRATORY MUCOSA;

ANTIGENS, CD146; CLUSTERED REGULARLY INTERSPACED SHORT PALINDROMIC REPEATS; GENE EXPRESSION; GENE KNOCKOUT TECHNIQUES; GENETIC VECTORS; HUMANS; INFLAMMATION; LENTIVIRUS; PRIMARY CELL CULTURE; RESPIRATORY MUCOSA;

EID: 84943449480     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2015.53     Document Type: Article

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