Enhancing survival motor neuron expression extends lifespan and attenuates neurodegeneration in mutant TDP-43 mice

Human Molecular Genetics

Volumn 25, Issue 18, 2016, Pages 4080-4093

  Perera, Nirma D ^a   Sheean, Rebecca K ^a   Crouch, Peter J ^a   White, Anthony R ^a   Horne, Malcolm K ^a   Turner, Bradley J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE KINASE; ANDROGEN RECEPTOR; RNA BINDING PROTEIN; SURVIVAL MOTOR NEURON PROTEIN; TAR DNA BINDING PROTEIN; DNA BINDING PROTEIN; SURVIVAL MOTOR NEURON PROTEIN 1; TDP-43 PROTEIN, MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CELL SURVIVAL; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; FEMALE; GAIT DISORDER; GEMINI OF COILED BODIES; HUMAN; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOREACTIVITY; MALE; MICROGLIA; MOTONEURON; MOUSE; NERVE DEGENERATION; NONHUMAN; PRIORITY JOURNAL; SPINAL MUSCULAR ATROPHY; TDP 43 PROTEINOPATHY; UPREGULATION; WESTERN BLOTTING; ANIMAL; BIOSYNTHESIS; CYTOPLASM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; PATHOLOGY; PROTEINOSIS; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ASTROCYTES; CYTOPLASM; DNA-BINDING PROTEINS; GENE EXPRESSION REGULATION; HUMANS; MICE; MICE, TRANSGENIC; MICROGLIA; MOTOR NEURONS; MUSCULAR ATROPHY, SPINAL; PROTEIN AGGREGATION, PATHOLOGICAL; SURVIVAL OF MOTOR NEURON 1 PROTEIN;

EID: 85014313797     PISSN: 09646906     EISSN: 14602083     Source Type: Journal    
DOI: 10.1093/hmg/ddw247     Document Type: Article

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