Effect of thymic stimulation of CD4+ T cell expansion on disease onset and progression in mutant SOD1 mice

Journal of Neuroinflammation

Volumn 12, Issue 1, 2015, Pages

  Sheean, Rebecca K ^a   Weston, Richard H ^a   Perera, Nirma D ^a   D'Amico, Angela ^a   Nutt, Stephen L ^a   Turner, Bradley J ^a  

^a UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

ALS; Androgen receptor; SBMA; SOD1; T cells; Tregs

Indexed keywords

ANDROGEN RECEPTOR; FORKHEAD TRANSCRIPTION FACTOR; FOXP3 PROTEIN, MOUSE; LEUKOCYTE ANTIGEN; SOD1 G93A PROTEIN; SUPEROXIDE DISMUTASE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; ASTROCYTE; CASTRATION; CD4+ FOXP3+ T LYMPHOCYTE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL EXPANSION; CELL LOSS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; DISEASE COURSE; DISEASE ONSET; FLUORESCENCE ACTIVATED CELL SORTING; GENERAL ASPECTS OF DISEASE; GLIA CELL; LYMPHOCYTE COUNT; MALE; MICROGLIA; MOTOR DYSFUNCTION; MOUSE; MSOD1 MOUSE; NERVOUS SYSTEM INFLAMMATION; NONHUMAN; PHENOTYPE; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; RECEPTOR DOWN REGULATION; REGULATORY T LYMPHOCYTE; SPINAL CORD; SPINAL CORD MOTONEURON; SPINAL MUSCULAR ATROPHY; SURVIVAL; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; THYMUS ATROPHY; THYMUS FUNCTION; WEIGHT REDUCTION; ANIMAL; BLOOD; C57BL MOUSE; DISEASE MODEL; FLOW CYTOMETRY; GENETICS; HUMAN; METABOLISM; MOTONEURON; PATHOLOGY; THYMUS; TRANSGENIC MOUSE;

AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; ANTIGENS, CD; CASTRATION; CD4-POSITIVE T-LYMPHOCYTES; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; FLOW CYTOMETRY; FORKHEAD TRANSCRIPTION FACTORS; HUMANS; MALE; MICE, INBRED C57BL; MICE, TRANSGENIC; MOTOR NEURONS; SPINAL CORD; SUPEROXIDE DISMUTASE; THYMUS GLAND;

EID: 84928738012     PISSN: None     EISSN: 17422094     Source Type: Journal    
DOI: 10.1186/s12974-015-0254-3     Document Type: Article

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