-
2
-
-
0035132167
-
Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis
-
Almer G., Guegan C., Teismann P. et al. (2001) Increased expression of the pro-inflammatory enzyme cyclooxygenase-2 in amyotrophic lateral sclerosis. Ann. Neurol. 49, 176-185.
-
(2001)
Ann. Neurol.
, vol.49
, pp. 176-185
-
-
Almer, G.1
Guegan, C.2
Teismann, P.3
-
3
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai T., Hasegawa M., Akiyama H. et al. (2006) TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochem. Biophys. Res. Commun. 351, 602-611.
-
(2006)
Biochem. Biophys. Res. Commun.
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
-
4
-
-
0030833055
-
Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins
-
Borchelt D.R., Ratovitski T., van Lare J. et al. (1997) Accelerated amyloid deposition in the brains of transgenic mice coexpressing mutant presenilin 1 and amyloid precursor proteins. Neuron 19, 939-945.
-
(1997)
Neuron
, vol.19
, pp. 939-945
-
-
Borchelt, D.R.1
Ratovitski, T.2
van Lare, J.3
-
5
-
-
0032544674
-
Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1
-
Bruijn L.I., Houseweart M.K., Kato S. et al. (1998) Aggregation and motor neuron toxicity of an ALS-linked SOD1 mutant independent from wild-type SOD1. Science, 281, 1851-1854.
-
(1998)
Science
, vol.281
, pp. 1851-1854
-
-
Bruijn, L.I.1
Houseweart, M.K.2
Kato, S.3
-
6
-
-
0001011390
-
Clinical and Pathological Studies of an Hereditary Neuropathy in Mice (Dystonia Musculorum)
-
Duchen L.W., Strich S.J., Falconer D.S. (1964) Clinical and Pathological Studies of an Hereditary Neuropathy in Mice (Dystonia Musculorum). Brain 87, 367-378.
-
(1964)
Brain
, vol.87
, pp. 367-378
-
-
Duchen, L.W.1
Strich, S.J.2
Falconer, D.S.3
-
7
-
-
80855138138
-
Rodent models of TDP-43 proteinopathy: investigating the mechanisms of TDP-43-mediated neurodegeneration
-
Gendron T.F., Petrucelli L. (2011) Rodent models of TDP-43 proteinopathy: investigating the mechanisms of TDP-43-mediated neurodegeneration. J. Mol. Neurosci. 45, 486-499.
-
(2011)
J. Mol. Neurosci.
, vol.45
, pp. 486-499
-
-
Gendron, T.F.1
Petrucelli, L.2
-
8
-
-
41949119043
-
TDP-43 A315T mutation in familial motor neuron disease
-
Gitcho M.A., Baloh R.H., Chakraverty S. et al. (2008) TDP-43 A315T mutation in familial motor neuron disease. Ann. Neurol. 63, 535-538.
-
(2008)
Ann. Neurol.
, vol.63
, pp. 535-538
-
-
Gitcho, M.A.1
Baloh, R.H.2
Chakraverty, S.3
-
9
-
-
84861636497
-
HO-1 induction in motor cortex and intestinal dysfunction in TDP-43 A315T transgenic mice
-
Guo Y., Wang Q., Zhang K. et al. (2012) HO-1 induction in motor cortex and intestinal dysfunction in TDP-43 A315T transgenic mice. Brain Res. 1460, 88-95.
-
(2012)
Brain Res.
, vol.1460
, pp. 88-95
-
-
Guo, Y.1
Wang, Q.2
Zhang, K.3
-
10
-
-
0041833409
-
Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis
-
Hensley K., Fedynyshyn J., Ferrell S. et al. (2003) Message and protein-level elevation of tumor necrosis factor alpha (TNF alpha) and TNF alpha-modulating cytokines in spinal cords of the G93A-SOD1 mouse model for amyotrophic lateral sclerosis. Neurobiol. Dis. 14, 74-80.
-
(2003)
Neurobiol. Dis.
, vol.14
, pp. 74-80
-
-
Hensley, K.1
Fedynyshyn, J.2
Ferrell, S.3
-
11
-
-
3042515545
-
Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis
-
Kabashi E., Agar J.N., Taylor D.M., Minotti S., Durham H.D. (2004) Focal dysfunction of the proteasome: a pathogenic factor in a mouse model of amyotrophic lateral sclerosis. J. Neurochem. 89, 1325-1335.
-
(2004)
J. Neurochem.
, vol.89
, pp. 1325-1335
-
-
Kabashi, E.1
Agar, J.N.2
Taylor, D.M.3
Minotti, S.4
Durham, H.D.5
-
12
-
-
42649120983
-
TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis
-
Kabashi E., Valdmanis P.N., Dion P. et al. (2008) TARDBP mutations in individuals with sporadic and familial amyotrophic lateral sclerosis. Nat. Genet. 40, 572-574.
-
(2008)
Nat. Genet.
, vol.40
, pp. 572-574
-
-
Kabashi, E.1
Valdmanis, P.N.2
Dion, P.3
-
13
-
-
17444367702
-
Integrative role of cPLA with COX-2 and the effect of non-steroidal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis
-
Kiaei M., Kipiani K., Petri S. et al. (2005) Integrative role of cPLA with COX-2 and the effect of non-steroidal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis. J. Neurochem. 93, 403-411.
-
(2005)
J. Neurochem.
, vol.93
, pp. 403-411
-
-
Kiaei, M.1
Kipiani, K.2
Petri, S.3
-
14
-
-
33645642112
-
Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis
-
Kiaei M., Petri S., Kipiani K. et al. (2006) Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis. J. Neurosci. 26, 2467-2473.
-
(2006)
J. Neurosci.
, vol.26
, pp. 2467-2473
-
-
Kiaei, M.1
Petri, S.2
Kipiani, K.3
-
15
-
-
61349156118
-
Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis
-
Kwiatkowski T.J. Jr, Bosco D.A., Leclerc A.L. et al. (2009) Mutations in the FUS/TLS gene on chromosome 16 cause familial amyotrophic lateral sclerosis. Science 323, 1205-1208.
-
(2009)
Science
, vol.323
, pp. 1205-1208
-
-
Kwiatkowski Jr., T.J.1
Bosco, D.A.2
Leclerc, A.L.3
-
16
-
-
0348011603
-
Functions of intermediate filaments in neuronal development and disease
-
Lariviere R.C., Julien J.P. (2004) Functions of intermediate filaments in neuronal development and disease. J. Neurobiol. 58, 131-148.
-
(2004)
J. Neurobiol.
, vol.58
, pp. 131-148
-
-
Lariviere, R.C.1
Julien, J.P.2
-
17
-
-
0035105962
-
Glutamate transporters in neurologic disease
-
Maragakis N.J., Rothstein J.D. (2001) Glutamate transporters in neurologic disease. Arch. Neurol. 58, 365-370.
-
(2001)
Arch. Neurol.
, vol.58
, pp. 365-370
-
-
Maragakis, N.J.1
Rothstein, J.D.2
-
18
-
-
33749632259
-
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann M., Sampathu D.M., Kwong L.K. et al. (2006) Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Science 314, 130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
-
19
-
-
33747605320
-
Molecular biology of amyotrophic lateral sclerosis: insights from genetics
-
Pasinelli P., Brown R.H. (2006) Molecular biology of amyotrophic lateral sclerosis: insights from genetics. Nat. Rev. Neurosci. 7, 710-723.
-
(2006)
Nat. Rev. Neurosci.
, vol.7
, pp. 710-723
-
-
Pasinelli, P.1
Brown, R.H.2
-
20
-
-
0942287085
-
Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance
-
Przedborski S. (2004) Programmed cell death in amyotrophic lateral sclerosis: a mechanism of pathogenic and therapeutic importance. Neurologist 10, 1-7.
-
(2004)
Neurologist
, vol.10
, pp. 1-7
-
-
Przedborski, S.1
-
21
-
-
0037068836
-
Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations
-
Raoul C., Estevez A.G., Nishimune H. et al. (2002) Motoneuron death triggered by a specific pathway downstream of Fas. potentiation by ALS-linked SOD1 mutations. Neuron, 35, 1067-1083.
-
(2002)
Neuron
, vol.35
, pp. 1067-1083
-
-
Raoul, C.1
Estevez, A.G.2
Nishimune, H.3
-
22
-
-
0029435316
-
Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis
-
Rothstein J.D. (1995) Excitotoxicity and neurodegeneration in amyotrophic lateral sclerosis. Clin. Neurosci. 3, 348-359.
-
(1995)
Clin. Neurosci.
, vol.3
, pp. 348-359
-
-
Rothstein, J.D.1
-
23
-
-
77958022745
-
Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice
-
Shan X., Chiang P.M., Price D.L., Wong P.C. (2010) Altered distributions of Gemini of coiled bodies and mitochondria in motor neurons of TDP-43 transgenic mice. Proc. Natl Acad. Sci. U.S.A. 107, 16325-16330.
-
(2010)
Proc. Natl Acad. Sci. U.S.A.
, vol.107
, pp. 16325-16330
-
-
Shan, X.1
Chiang, P.M.2
Price, D.L.3
Wong, P.C.4
-
24
-
-
42049120518
-
Progranulin genetic variability contributes to amyotrophic lateral sclerosis
-
Sleegers K., Brouwers N., Maurer-Stroh S. et al. (2008) Progranulin genetic variability contributes to amyotrophic lateral sclerosis. Neurology 71, 253-259.
-
(2008)
Neurology
, vol.71
, pp. 253-259
-
-
Sleegers, K.1
Brouwers, N.2
Maurer-Stroh, S.3
-
25
-
-
79251518539
-
Progressive motor weakness in transgenic mice expressing human TDP-43
-
Stallings N.R., Puttaparthi K., Luther C.M., Burns D.K., Elliott J.L. (2010) Progressive motor weakness in transgenic mice expressing human TDP-43. Neurobiol. Dis. 40, 404-414.
-
(2010)
Neurobiol. Dis.
, vol.40
, pp. 404-414
-
-
Stallings, N.R.1
Puttaparthi, K.2
Luther, C.M.3
Burns, D.K.4
Elliott, J.L.5
-
26
-
-
84855515796
-
Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor kappaB-mediated pathogenic pathways
-
Swarup V., Phaneuf D., Dupre N. et al. (2011) Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor kappaB-mediated pathogenic pathways. J. Exp. Med. 208, 2429-2447.
-
(2011)
J. Exp. Med.
, vol.208
, pp. 2429-2447
-
-
Swarup, V.1
Phaneuf, D.2
Dupre, N.3
-
27
-
-
63949083624
-
Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression
-
Tatom J.B., Wang D.B., Dayton R.D. et al. (2009) Mimicking aspects of frontotemporal lobar degeneration and Lou Gehrig's disease in rats via TDP-43 overexpression. Mol. Ther. 17, 607-613.
-
(2009)
Mol. Ther.
, vol.17
, pp. 607-613
-
-
Tatom, J.B.1
Wang, D.B.2
Dayton, R.D.3
-
28
-
-
3042817421
-
CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70
-
Urushitani M., Kurisu J., Tateno M. et al. (2004) CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70. J. Neurochem. 90, 231-244.
-
(2004)
J. Neurochem.
, vol.90
, pp. 231-244
-
-
Urushitani, M.1
Kurisu, J.2
Tateno, M.3
-
29
-
-
61349162349
-
Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6
-
Vance C., Rogelj B., Hortobagyi T. et al. (2009) Mutations in FUS, an RNA processing protein, cause familial amyotrophic lateral sclerosis type 6. Science, 323, 1208-1211.
-
(2009)
Science
, vol.323
, pp. 1208-1211
-
-
Vance, C.1
Rogelj, B.2
Hortobagyi, T.3
-
30
-
-
26244451092
-
Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA
-
Wang J., Xu G., Slunt H.H. et al. (2005) Coincident thresholds of mutant protein for paralytic disease and protein aggregation caused by restrictively expressed superoxide dismutase cDNA. Neurobiol. Dis. 20, 943-952.
-
(2005)
Neurobiol. Dis.
, vol.20
, pp. 943-952
-
-
Wang, J.1
Xu, G.2
Slunt, H.H.3
-
31
-
-
73249152831
-
TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration
-
Wegorzewska I., Bell S., Cairns N.J., Miller T.M., Baloh R.H. (2009) TDP-43 mutant transgenic mice develop features of ALS and frontotemporal lobar degeneration. Proc. Natl Acad. Sci. U.S.A. 106, 18809-18814.
-
(2009)
Proc. Natl Acad. Sci. U.S.A.
, vol.106
, pp. 18809-18814
-
-
Wegorzewska, I.1
Bell, S.2
Cairns, N.J.3
Miller, T.M.4
Baloh, R.H.5
-
32
-
-
77649269011
-
TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration
-
Wils H., Kleinberger G., Janssens J. et al. (2010) TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration. Proc. Natl Acad. Sci. U.S.A. 107, 3858-3863.
-
(2010)
Proc. Natl Acad. Sci. U.S.A.
, vol.107
, pp. 3858-3863
-
-
Wils, H.1
Kleinberger, G.2
Janssens, J.3
-
34
-
-
10244236554
-
Mitochondrial degeneration in amyotrophic lateral sclerosis
-
Xu Z., Jung C., Higgins C., Levine J., Kong J. (2004) Mitochondrial degeneration in amyotrophic lateral sclerosis. J. Bioenerg. Biomembr. 36, 395-399.
-
(2004)
J. Bioenerg. Biomembr.
, vol.36
, pp. 395-399
-
-
Xu, Z.1
Jung, C.2
Higgins, C.3
Levine, J.4
Kong, J.5
-
35
-
-
42949094584
-
TDP-43 mutation in familial amyotrophic lateral sclerosis
-
Yokoseki A., Shiga A., Tan C.F. et al. (2008) TDP-43 mutation in familial amyotrophic lateral sclerosis. Ann. Neurol. 63, 538-542.
-
(2008)
Ann. Neurol.
, vol.63
, pp. 538-542
-
-
Yokoseki, A.1
Shiga, A.2
Tan, C.F.3
|