Mass Spectrometry Profiling of HLA-Associated Peptidomes in Mono-allelic Cells Enables More Accurate Epitope Prediction

Immunity

Volumn 46, Issue 2, 2017, Pages 315-326

  Abelin, Jennifer G ^a   Keskin, Derin B ^a,b,c,d,h   Sarkizova, Siranush ^a,b   Hartigan, Christina R ^a   Zhang, Wandi ^c   Sidney, John ^e   Stevens, Jonathan ^d   Lane, William ^d   Zhang, Guang Lan ^b,c,h   Eisenhaure, Thomas M ^a   Clauser, Karl R ^a   Hacohen, Nir ^a,c,i   Rooney, Michael S ^a,f,g   Carr, Steven A ^a   Wu, Catherine J ^a,b,c,d  

^a BROAD INSTITUTE OF MIT AND HARVARD   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c DANA FARBER CANCER INSTITUTE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

^e LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^f HARVARD MIT DIVISION OF HEALTH SCIENCES AND TECHNOLOGY   (United States)

^g Neon Therapeutics Inc   (United States)

^h BOSTON UNIVERSITY   (United States)

ⁱ MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EPITOPE; PROTEASOME; HLA ANTIGEN CLASS 1; PEPTIDE;

ALLELE; AMINO ACID SEQUENCE; ANTIGEN PRESENTATION; ARTICLE; B LYMPHOCYTE; BINDING AFFINITY; COMPARATIVE STUDY; ENZYME SPECIFICITY; GENE EXPRESSION; GENE FREQUENCY; GENE SEQUENCE; HLA SYSTEM; HUMAN; HUMAN CELL; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; PREDICTION; PRIORITY JOURNAL; PROTEIN CLEAVAGE; PROTEIN LOCALIZATION; TANDEM MASS SPECTROMETRY; ALGORITHM; ARTIFICIAL NEURAL NETWORK; CELL LINE; GENE EXPRESSION PROFILING; GENETICS; IMMUNOLOGY; LIQUID CHROMATOGRAPHY; PROCEDURES; PROTEIN DOMAIN;

ALGORITHMS; ALLELES; ANTIGEN PRESENTATION; CELL LINE; CHROMATOGRAPHY, LIQUID; EPITOPES; GENE EXPRESSION PROFILING; HISTOCOMPATIBILITY ANTIGENS CLASS I; HUMANS; NEURAL NETWORKS (COMPUTER); PEPTIDES; PROTEIN INTERACTION DOMAINS AND MOTIFS; TANDEM MASS SPECTROMETRY;

EID: 85013878753     PISSN: 10747613     EISSN: 10974180     Source Type: Journal    
DOI: 10.1016/j.immuni.2017.02.007     Document Type: Article

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