Positional Bias of MHC Class I Restricted T-Cell Epitopes in Viral Antigens Is Likely due to a Bias in Conservation

PLoS Computational Biology

Volumn 9, Issue 1, 2013, Pages

  Kim, Yohan ^a   Yewdell, Jonathan W ^b   Sette, Alessandro ^a   Peters, Bjoern ^a  

^a LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY   (United States)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOSYNTHESIS; PEPTIDES; T-CELLS;

CLASS I; DOWN-STREAM; HALF LIVES; INFECTED CELLS; MATURE PROTEINS; N TERMINUS; POTENTIAL SOURCES; PROTEIN TURNOVERS; T-CELL EPITOPES; VIRAL PEPTIDES;

EPITOPES;

BINDING PROTEIN; EPITOPE; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; VIRUS ANTIGEN;

ARTICLE; CARBOXY TERMINAL SEQUENCE; DENGUE VIRUS; EPSTEIN BARR VIRUS; EQUINE INFECTIOUS ANEMIA VIRUS; GENETIC CONSERVATION; HANTAVIRUS; HEPATITIS B VIRUS; HEPATITIS C VIRUS; HERPES SIMPLEX VIRUS; HERPES SIMPLEX VIRUS 1; HUMAN HERPESVIRUS 8; HUMAN PAPILLOMAVIRUS TYPE 16; INFLUENZA VIRUS A; LYMPHOCYTIC CHORIOMENINGITIS VIRUS; MURINE ENCEPHALOMYELITIS VIRUS; MURINE HEPATITIS CORONAVIRUS; NONHUMAN; PROTEIN DEGRADATION; PROTEIN METABOLISM; PROTEIN SYNTHESIS; RESPIRATORY SYNCYTIAL PNEUMOVIRUS; T LYMPHOCYTE; VACCINIA VIRUS; WEST NILE FLAVIVIRUS; YELLOW FEVER FLAVIVIRUS;

EID: 84873489169     PISSN: 1553734X     EISSN: 15537358     Source Type: Journal    
DOI: 10.1371/journal.pcbi.1002884     Document Type: Article

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