Mathematical modeling links Wnt signaling to emergent patterns of metabolism in colon cancer

Molecular Systems Biology

Volumn 13, Issue 2, 2017, Pages

  Lee, Mary ^a   Chen, George T ^b   Puttock, Eric ^a   Wang, Kehui ^b,c   Edwards, Robert A ^b,c   Waterman, Marian L ^a,b,c   Lowengrub, John ^a,c,d  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d University of California at Irvine   (United States)

Author keywords

glycolysis; spatial pattern; tumor metabolism; Warburg effect; Wnt signaling

Indexed keywords

7,8 DIHYDRO 2 [4 (TRIFLUOROMETHYL)PHENYL] 5H THIOPYRANO[4,3 D]PYRIMIDIN 4 OL; BETA CATENIN; DICHLOROACETIC ACID; LYMPHOID ENHANCER FACTOR 1; PYRUVATE DEHYDROGENASE KINASE; WNT PROTEIN; PROTEIN SERINE THREONINE KINASE; PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING) KINASE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; CELL KILLING; CELL METABOLISM; CELL POPULATION; CHEMORADIOTHERAPY; COLON CANCER; COLORECTAL CANCER; CONTROLLED STUDY; DIFFUSION; DRUG TARGETING; ENZYME ACTIVITY; FEMALE; GLYCOLYSIS; HUMAN; HUMAN TISSUE; MALE; MATHEMATICAL MODEL; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; SIMULATION; TUMOR SPHEROID; TUMOR XENOGRAFT; WNT SIGNALING PATHWAY; ANIMAL; CANCER TRANSPLANTATION; COLON TUMOR; GENE EXPRESSION REGULATION; METABOLISM; THEORETICAL MODEL; TUMOR CELL LINE; UPREGULATION;

ANIMALS; CELL LINE, TUMOR; COLONIC NEOPLASMS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOLYSIS; HUMANS; MICE; MODELS, THEORETICAL; NEOPLASM TRANSPLANTATION; PROTEIN-SERINE-THREONINE KINASES; UP-REGULATION; WNT SIGNALING PATHWAY;

EID: 85013872279     PISSN: None     EISSN: 17444292     Source Type: Journal    
DOI: 10.15252/msb.20167386     Document Type: Article

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