A microscale mathematical model for metabolic symbiosis: Investigating the effects of metabolic inhibition on ATP turnover in tumors

Journal of Theoretical Biology

Volumn 366, Issue , 2015, Pages 103-114

  Phipps, Colin ^a   Molavian, Hamid ^a   Kohandel, Mohammad ^a,b  

^a UNIVERSITY OF WATERLOO   (Canada)

^b FIELDS INSTITUTE   (Canada)

Author keywords

Cancer cell metabolism; Glycolytic inhibition; Lactate dehydrogenase inhibitor; Tumor hypoxia; Warburg effect

Indexed keywords

ADENOSINE TRIPHOSPHATE; GLUCOSE; LACTATE DEHYDROGENASE; LACTIC ACID; OXYGEN;

CANCER; DIFFUSION; ENZYME; INHIBITION; METABOLISM; POPULATION GENETICS; SYMBIOSIS; TUMOR;

APOPTOSIS; ARTICLE; BLOOD VESSEL; CANCER CELL; CELL POPULATION; CHEMICAL REACTION; DIFFUSION; ENZYME INHIBITION; GLYCOLYSIS; HUMAN; MATHEMATICAL MODEL; METABOLIC INHIBITION; MICROVASCULATURE; NEOPLASM; SYMBIOSIS; TURNOVER TIME; ANIMAL; BIOLOGICAL MODEL; CELL PROLIFERATION; COMPUTER SIMULATION; METABOLISM; OXYGEN CONSUMPTION;

ADENOSINE TRIPHOSPHATE; ANIMALS; CELL PROLIFERATION; COMPUTER SIMULATION; GLUCOSE; GLYCOLYSIS; HUMANS; LACTIC ACID; MODELS, BIOLOGICAL; NEOPLASMS; OXYGEN CONSUMPTION; SYMBIOSIS;

EID: 84916919837     PISSN: 00225193     EISSN: 10958541     Source Type: Journal    
DOI: 10.1016/j.jtbi.2014.11.016     Document Type: Article

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