Visualization of a short-range Wnt gradient in the intestinal stem-cell niche

Nature

Volumn 530, Issue 7590, 2016, Pages 340-343

  Farin, Henner F ^a,b,c   Jordens, Ingrid ^a   Mosa, Mohammed H ^b,c   Basak, Onur ^a   Korving, Jeroen ^a   Tauriello, Daniele V F ^a   De Punder, Karin ^d   Angers, Stephane ^e   Peters, Peter J ^d   Maurice, Madelon M ^a   Clevers, Hans ^a  

^a UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^b GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^c INSTITUTE FOR TUMOR BIOLOGY AND EXPERIMENTAL THERAPY   (Germany)

^d MAASTRICHT UNIVERSITY   (Netherlands)

^e UNIVERSITY OF TORONTO   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

E3 LIGASE RNF43; E3 LIGASE ZNRF3; FRIZZLED PROTEIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; WNT PROTEIN; WNT3 PROTEIN; G PROTEIN COUPLED RECEPTOR; LGR4 PROTEIN, MOUSE; RNF43 PROTEIN, MOUSE; SIGNAL PEPTIDE; UBIQUITIN PROTEIN LIGASE; WNT3 PROTEIN, MOUSE; ZNRF3 PROTEIN, MOUSE;

ALLELE; CELLS AND CELL COMPONENTS; DIFFERENTIATION; ENZYME ACTIVITY; GENE EXPRESSION; MEMBRANE; PLASMA; PROTEIN; SECRETION;

ALLELE; ANIMAL CELL; ARTICLE; BASOLATERAL MEMBRANE; CELL PROLIFERATION; CONTROLLED STUDY; CYTOPLASM; IN VITRO STUDY; INTESTINAL STEM CELL; MOUSE; NONHUMAN; PANETH CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SECRETION; STEM CELL NICHE; ANIMAL; CELL ADHESION; CELL DIVISION; CELL MEMBRANE; CYTOLOGY; DIFFUSION; FEMALE; GENE TARGETING; GENETICS; INTESTINE MUCOSA; MALE; METABOLISM; SECRETION (PROCESS); STEM CELL; WNT SIGNALING PATHWAY;

MAMMALIA;

ALLELES; ANIMALS; CELL ADHESION; CELL DIVISION; CELL MEMBRANE; DIFFUSION; FEMALE; FRIZZLED RECEPTORS; GENE KNOCK-IN TECHNIQUES; INTERCELLULAR SIGNALING PEPTIDES AND PROTEINS; INTESTINAL MUCOSA; MALE; MICE; ORGANOIDS; PANETH CELLS; RECEPTORS, G-PROTEIN-COUPLED; STEM CELL NICHE; STEM CELLS; UBIQUITIN-PROTEIN LIGASES; WNT SIGNALING PATHWAY; WNT3 PROTEIN;

EID: 84959017482     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature16937     Document Type: Article

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