sFRP-2 is a target of the Wnt-4 signaling pathway in the developing metanephric kidney

Developmental Dynamics

Volumn 213, Issue 4, 1998, Pages 440-451

  Lescher, Birgit ^a   Haenig, Bénédicte ^a   Kispert, Andreas ^a  

^a MAX PLANCK INSTITUTE OF IMMUNOBIOLOGY AND EPIGENETICS   (Germany)

Author keywords

Development; Expression analysis; Kidney; Metanephros; Mouse; SDF5; Secreted frizzled related protein; sFRP 2; Wnt 4

Indexed keywords

CYSTEINE; GLYCOPROTEIN; SFRP PROTEIN; UNCLASSIFIED DRUG; WNT4 PROTEIN;

ANIMAL CELL; ARTICLE; EMBRYO; EMBRYO DEVELOPMENT; GENE EXPRESSION REGULATION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; KIDNEY DEVELOPMENT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN SECRETION; SEQUENCE ANALYSIS;

ANIMALS; CELL LINE, TRANSFORMED; FRIZZLED RECEPTORS; GENE EXPRESSION; HUMANS; IN SITU HYBRIDIZATION; KIDNEY; MICE; PROTO-ONCOGENE PROTEINS; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, NEUROTRANSMITTER; SIGNAL TRANSDUCTION; WNT PROTEINS;

EID: 0031730117     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/(SICI)1097-0177(199812)213:4<440::AID-AJA9>3.0.CO;2-6     Document Type: Article

References (38)

1. Bhanot P, Brink M, Samos CH, Hsieh J-C, Wang Y, Macke JP, Andrew D, Nathans J. 1996. A new member of the frizzled family from Drosophila functions as a Wingless receptor. Nature 382:225-230.
2. Bradley RS, Brown AMC. 1990. The proto-oncogene int-1 encodes a secreted protein associated with the extracellular matrix. EMBO J 9:1569-1575.
3. Burrus LW. 1994. Wnt-1 as a short-range signaling molecule. Bioessays 16:155-157.
4. Burrus LW, McMahon AP. 1995. Biochemical analysis of murine Wnt proteins reveals both shared and distinct properties. Exp Cell Res 220:363-373.
5. Chan SDH, Karpf DB, Fowlkes ME, Hooks M, Bradley MS, Vuong V, Bambino T, Liu MYC, Arnaud CD, Strewler GJ, Nissenson RA. 1992. Two homologs of the Drosophila polarity gene frizzled (fz) are widely expressed in mammalian tissues. J Biol Chem 267:25202-25207.
6. Finch PW, He X, Kelley MJ, Uren A, Schaudies RP, Popescu NC, Rudikoff S, Aaronson SA, Varmus HE, Rubin, JS. 1997. Purification and molecular cloning of a secreted, Frizzled-related antagonist of Wnt action. Proc Natl Acad Sci USA 94:6770-6775.
7. Gavin BJ, McMahon JA, McMahon AP. 1990. Expression of multiple novel Wnt-1 / int-1-related genes during fetal and adult mouse development. Genes Dev 4:2319-2332.
8. Glinka A, Wu W, Onichtchouk D, Blumenstock C, Niehrs C. 1997. Head induction by simultaneous repression of Bmp and Wnt signalling in Xenopus. Nature 389:517-519.
9. Glinka A, Wu W, Delius H, Monaghan AP, Blumenstock C, Niehrs C. 1998. Dickkopf-1 is a member of a new family of secreted proteins and functions in head induction. Nature 391:357-362.
10. Hoang BH, Thomas JT, Abdul-Karim FW, Correia KM, Conlon RA, Luyten FP, Ballock RT. 1998. Expression pattern of two frizzled-related genes, Frzb-1 and Sfrp-1, during moue embryogenesis suggests a role for modulating action of Wnt family members. Dev Dyn 212:364-372.
11. Kispert A, Vainio S, Shen L, Rowitch DR, McMahon AP. 1996. Proteoglycans are required for maintenance of Wnt-11 expression in the ureter tips. Development 122:3627-3637.
12. Kispert A, Vainio S, McMahon AP. 1998. Wnt-4 is a mesenchymal signal for epithelial transformation of metanephric mesenchyme in the developing kidney. Development 125:4225-4234.
13. Knecht AK, Good PJ, Dawid IB, Harland RM. 1995. Dorsal-ventral patterning and differentiation of noggin-induced neural tissue in the absence of mesoderm. Development 121:1927-1936.
14. Lechner MA, Dressier GR. 1997. The molecular basis of embryonic kidney development. Mech Dev 62:105-120.
15. Lee SMK, Dickinson ME, Parr, BA, Vainio S, McMahon AP. 1995. Molecular genetic analysis of Wnt signals in mouse development. Semin Dev Biol 6:267-274.
16. Lemaire P, Gurdon JB. 1994. A role for cytoplasmic determinants in mesoderm patterning: Cell-autonomous activation of the goosecoid and Xwnt-8 genes along the dorsoventral axis of early Xenopus embryos. Development 120:1191-1199.
17. Leyns L, Bouwmeester T, Kim SH, Piccolo S, De Robertis EM. 1997. Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer. Cell 88:747-756.
18. Lin K, Wang S, Julius MA, Kitajewski J, Moos M, Luyten FP. 1997. The cysteine-rich frizzled domain of Frzb-1 is required and sufficient for modulation of Wnt signaling. Proc Natl Acad Sci USA 94:11196-11200.
19. Mayr T, Deutsch U, Kuhl M, Drexler HC, Lottspeich F, Deutzmann R, Wedlich D, Risau W. 1997. Fritz: A secreted frizzled-related protein that inhibits Wnt activity. Mech Dev 63:109-120.
20. McMahon AP, Bradley A. 1990. The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain. Cell 62:1073-1085.
21. Melkonyan HS, Chang WC, Shapiro JP, Mahadevappa M, Fitzpatrick PA, Kiefer MC, Tomei LD, Umansky SR. 1997. SARPs: A family of secreted apoptosis-related proteins. Proc Natl Acad Sci USA 94: 13636-13641.
22. Moon RT, Brown JD, Yang-Synder JA, Miller JR. 1997. Structurally related receptors and antagonists compete for secreted Wnt ligands. Cell 88:725-728.
23. Papkoff J, Schryver B. 1990. Secreted int-1 protein is associated with the cell surface. Mol Cell Biol 10:2723-2730.
24. Parr B, McMahon AP. 1995. Dorsalizing signal Wnt-7a required for normal polarity of D-V and A-P axes of mouse limb. Nature 374:350-353.
25. Parr BA, Shea MJ, Vassileva G, McMahon AP. 1993. Mouse Wnt genes exhibit discrete domains of expression in the early embryonic CNS and limb buds. Development 119:247-261.
26. Pear WS, Nolan GP, Scott ML, Baltimore D. 1993. Production of high-titer helper-free retroviruses by transient transfection. Proc Natl Acad Sci USA 90:8392-8396.
27. Pfeffer PL, DeRobertis EM, Izpisua-Belmonte JC. 1997. Crescent, a novel chick gene encoding a Frizzled-like cysteine-rich domain, is expressed in anterior regions during early embryogenesis. Int J Dev Biol 41:449-458.
28. Rattner A, Hsieh JC, Smallwood PM, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J. 1997. A family of secreted proteins contains homology to the cysteine-rich ligand-binding domain of frizzled receptors. Proc Natl Acad Sci USA 94:2859-2863.
29. Saxen L. 1987. Organogenesis of the kidney. Cambridge: Cambridge University Press.
30. Salic AN, Kroll KL, Evans LM, Kirschner MW. 1997. Sizzled: A secreted Xwnt8 antagonist expressed in the ventral marginal zone of Xenopus embryos. Development 124:4739-4748.
31. Shirozu M, Tada H, Tashiro K, Nakamura T, Lopez ND, Nazarea M, Hamada T, Sato T, Nakano T, Honjo T. 1996. Characterization of novel secreted and membrane proteins isolated by the signal sequence trap method. Genomics 37:273-280.
32. Stark K, Vainio S, Vassileva G, McMahon AP. 1994. Epithelial transformation of metanephric mesenchyme in the developing kidney regulated by Wnt-4. Nature 372:679-683.
33. Takada S, Stark KL, Shea MJ, Vassileva G, McMahon JA, McMahon AP. 1993. Wnt-3a regulates somite and tailbud formation in the mouse embryo. Genes Dev 8:174-189.
34. Thomas KR, Capecchi MR. 1990. Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development. Nature 346:847-850.
35. Vainio S, Muller U. 1997. Inductive tissue interactions, cell signaling, and the control of kidney Organogenesis. Cell 90:975-978.
36. Wang S. Krinks M, Lin K, Luyten FP, Moos M Jr. 1997. Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8. Cell 88:757-66.
37. Wang Y, Macke JP, Abella BS, Andreasson K, Worley P, Gilbert DJ, Copeland NG, Jenkins NA, Nathans J. 1996. A large family of putative transmembrane receptor homologous to the product of the Drosophila tissue polarity gene frizzled. J Biol Chem 271:4468-4476.
38. Zorn AM. 1997. Cell-cell signalling: Frog frizbees. Curr Biol 7:501-504.