P2Y12 receptors in primary microglia activate nuclear factor of activated T-cell signaling to induce C–C chemokine 3 expression

Journal of Neurochemistry

Volumn 141, Issue 1, 2017, Pages 100-110

  Tozaki Saitoh, Hidetoshi ^a   Miyata, Hiroyuki ^a   Yamashita, Tomohiro ^a   Matsushita, Katsuyuki ^b   Tsuda, Makoto ^a   Inoue, Kazuhide ^a  

^a KYUSHU UNIVERSITY   (Japan)

^b KYUSHU UNIVERSITY   (Japan)

Author keywords

chemokine; microglia; purinergic signaling

Indexed keywords

ADENOSINE TRIPHOSPHATE; CALCINEURIN; CALCIUM; CALCIUM CHELATING AGENT; CYCLIC AMP; CYCLIC AMP DEPENDENT PROTEIN KINASE; KT 5720; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; PERTUSSIS TOXIN; PHOSPHOLIPASE C; PURINERGIC P2Y12 RECEPTOR; TRANSCRIPTION FACTOR NFAT; ADENOSINE DIPHOSPHATE;

ANIMAL CELL; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CELL NUCLEUS; CELL STIMULATION; CELLULAR DISTRIBUTION; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CYTOKINE RELEASE; DEPHOSPHORYLATION; GENE ACTIVATION; GENE EXPRESSION; GENE SEQUENCE; INTRACELLULAR SIGNALING; MICROGLIA; NEWBORN; NONHUMAN; PROTEIN FUNCTION; PROTEIN SECRETION; QUANTITATIVE ANALYSIS; RAT; T LYMPHOCYTE ACTIVATION; AGONISTS; ANIMAL; BIOSYNTHESIS; CELL CULTURE; DOSE RESPONSE; DRUG EFFECTS; GENETICS; METABOLISM; PHYSIOLOGY; SIGNAL TRANSDUCTION; WISTAR RAT;

ADENOSINE DIPHOSPHATE; ANIMALS; ANIMALS, NEWBORN; CELLS, CULTURED; CHEMOKINE CCL3; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION; MICROGLIA; NFATC TRANSCRIPTION FACTORS; RATS; RATS, WISTAR; RECEPTORS, PURINERGIC P2Y12; SIGNAL TRANSDUCTION;

EID: 85013663335     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/jnc.13968     Document Type: Article

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