메뉴 건너뛰기




Volumn 12, Issue 1, 2012, Pages 74-79

Purinergic system, microglia and neuropathic pain

Author keywords

[No Author keywords available]

Indexed keywords

4 AMINOBUTYRIC ACID A RECEPTOR; A 438079; A 740003; ANTISENSE OLIGONUCLEOTIDE; ARC 69931MX; BRAIN DERIVED NEUROTROPHIC FACTOR; CASPASE RECRUITMENT DOMAIN PROTEIN 15; INTERLEUKIN 1BETA; MRS 2395; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; PURINERGIC P2X RECEPTOR; PURINERGIC P2X4 RECEPTOR; PURINERGIC P2X7 RECEPTOR; PURINERGIC P2Y RECEPTOR; PURINERGIC P2Y12 RECEPTOR; PURINERGIC RECEPTOR; PURINERGIC RECEPTOR BLOCKING AGENT; SECONDARY LYMPHOID TISSUE CHEMOKINE; UNCLASSIFIED DRUG;

EID: 84857235527     PISSN: 14714892     EISSN: 14714973     Source Type: Journal    
DOI: 10.1016/j.coph.2011.10.014     Document Type: Review
Times cited : (49)

References (51)
  • 1
    • 35548937457 scopus 로고    scopus 로고
    • The neuropathic pain triad: Neurons, immune cells and glia
    • J. Scholz, and C.J. Woolf The neuropathic pain triad: neurons, immune cells and glia Nat Neurosci 10 2007 1361 1368
    • (2007) Nat Neurosci , vol.10 , pp. 1361-1368
    • Scholz, J.1    Woolf, C.J.2
  • 2
    • 34848843543 scopus 로고    scopus 로고
    • Neurotransmitter receptors on microglia
    • J.M. Pocock, and H. Kettenmann Neurotransmitter receptors on microglia Trends Neurosci 30 2007 527 535
    • (2007) Trends Neurosci , vol.30 , pp. 527-535
    • Pocock, J.M.1    Kettenmann, H.2
  • 5
    • 67650222417 scopus 로고    scopus 로고
    • Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays
    • M. Tsuda, K. Kuboyama, T. Inoue, K. Nagata, H. Tozaki-Saitoh, and K. Inoue Behavioral phenotypes of mice lacking purinergic P2X4 receptors in acute and chronic pain assays Mol Pain 5 2009 28
    • (2009) Mol Pain , vol.5 , pp. 28
    • Tsuda, M.1    Kuboyama, K.2    Inoue, T.3    Nagata, K.4    Tozaki-Saitoh, H.5    Inoue, K.6
  • 6
    • 13144276331 scopus 로고    scopus 로고
    • Neuropathic pain and spinal microglia: A big problem from molecules in "small" glia
    • M. Tsuda, K. Inoue, and M.W. Salter Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia Trends Neurosci 28 2005 101 107
    • (2005) Trends Neurosci , vol.28 , pp. 101-107
    • Tsuda, M.1    Inoue, K.2    Salter, M.W.3
  • 7
    • 33748588153 scopus 로고    scopus 로고
    • Combinations of TLR and NOD2 ligands stimulate rat microglial P2X4R expression
    • L.H. Guo, K.T. Guo, H.P. Wendel, and H.J. Schluesener Combinations of TLR and NOD2 ligands stimulate rat microglial P2X4R expression Biochem Biophys Res Commun 349 2006 1156 1162
    • (2006) Biochem Biophys Res Commun , vol.349 , pp. 1156-1162
    • Guo, L.H.1    Guo, K.T.2    Wendel, H.P.3    Schluesener, H.J.4
  • 9
    • 33646259685 scopus 로고    scopus 로고
    • Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X(4), a key molecule for mechanical allodynia
    • K. Nasu-Tada, S. Koizumi, M. Tsuda, E. Kunifusa, and K. Inoue Possible involvement of increase in spinal fibronectin following peripheral nerve injury in upregulation of microglial P2X(4), a key molecule for mechanical allodynia Glia 53 2006 769 775
    • (2006) Glia , vol.53 , pp. 769-775
    • Nasu-Tada, K.1    Koizumi, S.2    Tsuda, M.3    Kunifusa, E.4    Inoue, K.5
  • 10
    • 77449099299 scopus 로고    scopus 로고
    • Mechanisms underlying fibronectin-induced upregulation of P2XR expression in microglia: Distinct roles of PI3K-Akt and MEK-ERK signaling pathways
    • M. Tsuda, E. Toyomitsu, M. Kometani, H. Tozaki-Saitoh, and K. Inoue Mechanisms underlying fibronectin-induced upregulation of P2XR expression in microglia: distinct roles of PI3K-Akt and MEK-ERK signaling pathways J Cell Mol Med 13 2009 3251 3259
    • (2009) J Cell Mol Med , vol.13 , pp. 3251-3259
    • Tsuda, M.1    Toyomitsu, E.2    Kometani, M.3    Tozaki-Saitoh, H.4    Inoue, K.5
  • 11
    • 44949248511 scopus 로고    scopus 로고
    • Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury
    • M. Tsuda, E. Toyomitsu, T. Komatsu, T. Masuda, E. Kunifusa, K. Nasu-Tada, S. Koizumi, K. Yamamoto, J. Ando, and K. Inoue Fibronectin/integrin system is involved in P2X(4) receptor upregulation in the spinal cord and neuropathic pain after nerve injury Glia 56 2008 579 585
    • (2008) Glia , vol.56 , pp. 579-585
    • Tsuda, M.1    Toyomitsu, E.2    Komatsu, T.3    Masuda, T.4    Kunifusa, E.5    Nasu-Tada, K.6    Koizumi, S.7    Yamamoto, K.8    Ando, J.9    Inoue, K.10
  • 12
    • 79960941570 scopus 로고    scopus 로고
    • Peripheral nerve injury alters blood-spinal cord barrier functional and molecular integrity through a selective inflammatory pathway
    • S. Echeverry, X.Q. Shi, S. Rivest, and J. Zhang Peripheral nerve injury alters blood-spinal cord barrier functional and molecular integrity through a selective inflammatory pathway J Neurosci 31 2011 10819 10828
    • (2011) J Neurosci , vol.31 , pp. 10819-10828
    • Echeverry, S.1    Shi, X.Q.2    Rivest, S.3    Zhang, J.4
  • 13
    • 36448966388 scopus 로고    scopus 로고
    • Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury
    • M. Tsuda, H. Tozaki-Saitoh, T. Masuda, E. Toyomitsu, T. Tezuka, T. Yamamoto, and K. Inoue Lyn tyrosine kinase is required for P2X(4) receptor upregulation and neuropathic pain after peripheral nerve injury Glia 56 2008 50 58
    • (2008) Glia , vol.56 , pp. 50-58
    • Tsuda, M.1    Tozaki-Saitoh, H.2    Masuda, T.3    Toyomitsu, E.4    Tezuka, T.5    Yamamoto, T.6    Inoue, K.7
  • 15
    • 36549041874 scopus 로고    scopus 로고
    • Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis
    • O.S. Qureshi, A. Paramasivam, J.C. Yu, and R.D. Murrell-Lagnado Regulation of P2X4 receptors by lysosomal targeting, glycan protection and exocytosis J Cell Sci 120 2007 3838 3849
    • (2007) J Cell Sci , vol.120 , pp. 3838-3849
    • Qureshi, O.S.1    Paramasivam, A.2    Yu, J.C.3    Murrell-Lagnado, R.D.4
  • 17
    • 63849192564 scopus 로고    scopus 로고
    • P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation
    • T. Trang, S. Beggs, X. Wan, and M.W. Salter P2X4-receptor-mediated synthesis and release of brain-derived neurotrophic factor in microglia is dependent on calcium and p38-mitogen-activated protein kinase activation J Neurosci 29 2009 3518 3528
    • (2009) J Neurosci , vol.29 , pp. 3518-3528
    • Trang, T.1    Beggs, S.2    Wan, X.3    Salter, M.W.4
  • 18
    • 0037705314 scopus 로고    scopus 로고
    • P38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain
    • S.X. Jin, Z.Y. Zhuang, C.J. Woolf, and R.R. Ji p38 mitogen-activated protein kinase is activated after a spinal nerve ligation in spinal cord microglia and dorsal root ganglion neurons and contributes to the generation of neuropathic pain J Neurosci 23 2003 4017 4022
    • (2003) J Neurosci , vol.23 , pp. 4017-4022
    • Jin, S.X.1    Zhuang, Z.Y.2    Woolf, C.J.3    Ji, R.R.4
  • 19
    • 0346655315 scopus 로고    scopus 로고
    • Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury
    • M. Tsuda, A. Mizokoshi, Y. Shigemoto-Mogami, S. Koizumi, and K. Inoue Activation of p38 mitogen-activated protein kinase in spinal hyperactive microglia contributes to pain hypersensitivity following peripheral nerve injury Glia 45 2004 89 95
    • (2004) Glia , vol.45 , pp. 89-95
    • Tsuda, M.1    Mizokoshi, A.2    Shigemoto-Mogami, Y.3    Koizumi, S.4    Inoue, K.5
  • 20
    • 1842731881 scopus 로고    scopus 로고
    • Src kinases: A hub for NMDA receptor regulation
    • M.W. Salter, and L.V. Kalia Src kinases: a hub for NMDA receptor regulation Nat Rev Neurosci 5 2004 317 328
    • (2004) Nat Rev Neurosci , vol.5 , pp. 317-328
    • Salter, M.W.1    Kalia, L.V.2
  • 21
  • 24
    • 34147159585 scopus 로고    scopus 로고
    • Long-term potentiation of neuronal excitation by neuron-glia interactions in the rat spinal dorsal horn
    • H. Ikeda, M. Tsuda, K. Inoue, and K. Murase Long-term potentiation of neuronal excitation by neuron-glia interactions in the rat spinal dorsal horn Eur J Neurosci 25 2007 1297 1306
    • (2007) Eur J Neurosci , vol.25 , pp. 1297-1306
    • Ikeda, H.1    Tsuda, M.2    Inoue, K.3    Murase, K.4
  • 25
    • 45549090676 scopus 로고    scopus 로고
    • Cytokine mechanisms of central sensitization: Distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cord
    • Y. Kawasaki, L. Zhang, J.K. Cheng, and R.R. Ji Cytokine mechanisms of central sensitization: distinct and overlapping role of interleukin-1beta, interleukin-6, and tumor necrosis factor-alpha in regulating synaptic and neuronal activity in the superficial spinal cord J Neurosci 28 2008 5189 5194
    • (2008) J Neurosci , vol.28 , pp. 5189-5194
    • Kawasaki, Y.1    Zhang, L.2    Cheng, J.K.3    Ji, R.R.4
  • 26
    • 28444486336 scopus 로고    scopus 로고
    • The function of microglia through purinergic receptors: Neuropathic pain and cytokine release
    • K. Inoue The function of microglia through purinergic receptors: Neuropathic pain and cytokine release Pharmacol Ther 109 2006 210 226
    • (2006) Pharmacol Ther , vol.109 , pp. 210-226
    • Inoue, K.1
  • 28
    • 33751165071 scopus 로고    scopus 로고
    • A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2- dimethylpropyl)-2-(3,4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat
    • P. Honore, D. Donnelly-Roberts, M.T. Namovic, G. Hsieh, C.Z. Zhu, J.P. Mikusa, G. Hernandez, C. Zhong, D.M. Gauvin, and P. Chandran A-740003 [N-(1-{[(cyanoimino)(5-quinolinylamino) methyl]amino}-2,2-dimethylpropyl)-2-(3, 4-dimethoxyphenyl)acetamide], a novel and selective P2X7 receptor antagonist, dose-dependently reduces neuropathic pain in the rat J Pharmacol Exp Ther 319 2006 1376 1385
    • (2006) J Pharmacol Exp Ther , vol.319 , pp. 1376-1385
    • Honore, P.1    Donnelly-Roberts, D.2    Namovic, M.T.3    Hsieh, G.4    Zhu, C.Z.5    Mikusa, J.P.6    Hernandez, G.7    Zhong, C.8    Gauvin, D.M.9    Chandran, P.10
  • 30
    • 0031054641 scopus 로고    scopus 로고
    • Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin
    • D. Ferrari, P. Chiozzi, S. Falzoni, S. Hanau, and F. Di Virgilio Purinergic modulation of interleukin-1 beta release from microglial cells stimulated with bacterial endotoxin J Exp Med 185 1997 579 582
    • (1997) J Exp Med , vol.185 , pp. 579-582
    • Ferrari, D.1    Chiozzi, P.2    Falzoni, S.3    Hanau, S.4    Di Virgilio, F.5
  • 31
    • 74949123761 scopus 로고    scopus 로고
    • P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide
    • A.K. Clark, A.A. Staniland, F. Marchand, T.K. Kaan, S.B. McMahon, and M. Malcangio P2X7-dependent release of interleukin-1beta and nociception in the spinal cord following lipopolysaccharide J Neurosci 30 2010 573 582
    • (2010) J Neurosci , vol.30 , pp. 573-582
    • Clark, A.K.1    Staniland, A.A.2    Marchand, F.3    Kaan, T.K.4    McMahon, S.B.5    Malcangio, M.6
  • 32
    • 78349245841 scopus 로고    scopus 로고
    • Cathepsin S release from primary cultured microglia is regulated by the P2X7 receptor
    • A.K. Clark, R. Wodarski, F. Guida, O. Sasso, and M. Malcangio Cathepsin S release from primary cultured microglia is regulated by the P2X7 receptor Glia 58 2010 1710 1726
    • (2010) Glia , vol.58 , pp. 1710-1726
    • Clark, A.K.1    Wodarski, R.2    Guida, F.3    Sasso, O.4    Malcangio, M.5
  • 34
    • 67649395964 scopus 로고    scopus 로고
    • Analysis of Assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells
    • M. Boumechache, M. Masin, J.M. Edwardson, D.C. Gorecki, and R. Murrell-Lagnado Analysis of Assembly and trafficking of native P2X4 and P2X7 receptor complexes in rodent immune cells J Biol Chem 284 2009 13446 13454
    • (2009) J Biol Chem , vol.284 , pp. 13446-13454
    • Boumechache, M.1    Masin, M.2    Edwardson, J.M.3    Gorecki, D.C.4    Murrell-Lagnado, R.5
  • 35
    • 44949147139 scopus 로고    scopus 로고
    • P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury
    • H. Tozaki-Saitoh, M. Tsuda, H. Miyata, K. Ueda, S. Kohsaka, and K. Inoue P2Y12 receptors in spinal microglia are required for neuropathic pain after peripheral nerve injury J Neurosci 28 2008 4949 4956
    • (2008) J Neurosci , vol.28 , pp. 4949-4956
    • Tozaki-Saitoh, H.1    Tsuda, M.2    Miyata, H.3    Ueda, K.4    Kohsaka, S.5    Inoue, K.6
  • 36
    • 40849089273 scopus 로고    scopus 로고
    • P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain
    • K. Kobayashi, H. Yamanaka, T. Fukuoka, Y. Dai, K. Obata, and K. Noguchi P2Y12 receptor upregulation in activated microglia is a gateway of p38 signaling and neuropathic pain J Neurosci 28 2008 2892 2902
    • (2008) J Neurosci , vol.28 , pp. 2892-2902
    • Kobayashi, K.1    Yamanaka, H.2    Fukuoka, T.3    Dai, Y.4    Obata, K.5    Noguchi, K.6
  • 37
    • 0344013132 scopus 로고    scopus 로고
    • Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain
    • Y. Sasaki, M. Hoshi, C. Akazawa, Y. Nakamura, H. Tsuzuki, K. Inoue, and S. Kohsaka Selective expression of Gi/o-coupled ATP receptor P2Y12 in microglia in rat brain Glia 44 2003 242 250
    • (2003) Glia , vol.44 , pp. 242-250
    • Sasaki, Y.1    Hoshi, M.2    Akazawa, C.3    Nakamura, Y.4    Tsuzuki, H.5    Inoue, K.6    Kohsaka, S.7
  • 38
  • 40
    • 33747189475 scopus 로고    scopus 로고
    • Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord
    • K. Kobayashi, T. Fukuoka, H. Yamanaka, Y. Dai, K. Obata, A. Tokunaga, and K. Noguchi Neurons and glial cells differentially express P2Y receptor mRNAs in the rat dorsal root ganglion and spinal cord J Comp Neurol 498 2006 443 454
    • (2006) J Comp Neurol , vol.498 , pp. 443-454
    • Kobayashi, K.1    Fukuoka, T.2    Yamanaka, H.3    Dai, Y.4    Obata, K.5    Tokunaga, A.6    Noguchi, K.7
  • 41
    • 0035869474 scopus 로고    scopus 로고
    • Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors
    • S. Honda, Y. Sasaki, K. Ohsawa, Y. Imai, Y. Nakamura, K. Inoue, and S. Kohsaka Extracellular ATP or ADP induce chemotaxis of cultured microglia through Gi/o-coupled P2Y receptors J Neurosci 21 2001 1975 1982
    • (2001) J Neurosci , vol.21 , pp. 1975-1982
    • Honda, S.1    Sasaki, Y.2    Ohsawa, K.3    Imai, Y.4    Nakamura, Y.5    Inoue, K.6    Kohsaka, S.7
  • 42
    • 33947540584 scopus 로고    scopus 로고
    • Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis
    • K. Ohsawa, Y. Irino, Y. Nakamura, C. Akazawa, K. Inoue, and S. Kohsaka Involvement of P2X4 and P2Y12 receptors in ATP-induced microglial chemotaxis Glia 55 2007 604 616
    • (2007) Glia , vol.55 , pp. 604-616
    • Ohsawa, K.1    Irino, Y.2    Nakamura, Y.3    Akazawa, C.4    Inoue, K.5    Kohsaka, S.6
  • 44
    • 78649362101 scopus 로고    scopus 로고
    • Nerve injury-activated microglia engulf myelinated axons in a P2Y12 signaling-dependent manner in the dorsal horn
    • M. Maeda, M. Tsuda, H. Tozaki-Saitoh, K. Inoue, and H. Kiyama Nerve injury-activated microglia engulf myelinated axons in a P2Y12 signaling-dependent manner in the dorsal horn Glia 58 2010 1838 1846
    • (2010) Glia , vol.58 , pp. 1838-1846
    • Maeda, M.1    Tsuda, M.2    Tozaki-Saitoh, H.3    Inoue, K.4    Kiyama, H.5
  • 46
    • 34447502253 scopus 로고    scopus 로고
    • Possible role of spinal astrocytes in maintaining chronic pain sensitization: Review of current evidence with focus on bFGF/JNK pathway
    • R.R. Ji, Y. Kawasaki, Z.Y. Zhuang, Y.R. Wen, and I. Decosterd Possible role of spinal astrocytes in maintaining chronic pain sensitization: review of current evidence with focus on bFGF/JNK pathway Neuron Glia Biol 2 2006 259 269
    • (2006) Neuron Glia Biol , vol.2 , pp. 259-269
    • Ji, R.R.1    Kawasaki, Y.2    Zhuang, Z.Y.3    Wen, Y.R.4    Decosterd, I.5
  • 47
    • 33645460235 scopus 로고    scopus 로고
    • A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: Respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance
    • Z.Y. Zhuang, Y.R. Wen, D.R. Zhang, T. Borsello, C. Bonny, G.R. Strichartz, I. Decosterd, and R.R. Ji A peptide c-Jun N-terminal kinase (JNK) inhibitor blocks mechanical allodynia after spinal nerve ligation: respective roles of JNK activation in primary sensory neurons and spinal astrocytes for neuropathic pain development and maintenance J Neurosci 26 2006 3551 3560
    • (2006) J Neurosci , vol.26 , pp. 3551-3560
    • Zhuang, Z.Y.1    Wen, Y.R.2    Zhang, D.R.3    Borsello, T.4    Bonny, C.5    Strichartz, G.R.6    Decosterd, I.7    Ji, R.R.8
  • 48
    • 48249124939 scopus 로고    scopus 로고
    • Transforming growth factor-activated kinase 1 induced in spinal astrocytes contributes to mechanical hypersensitivity after nerve injury
    • H. Katsura, K. Obata, K. Miyoshi, T. Kondo, H. Yamanaka, K. Kobayashi, Y. Dai, T. Fukuoka, M. Sakagami, and K. Noguchi Transforming growth factor-activated kinase 1 induced in spinal astrocytes contributes to mechanical hypersensitivity after nerve injury Glia 56 2008 723 733
    • (2008) Glia , vol.56 , pp. 723-733
    • Katsura, H.1    Obata, K.2    Miyoshi, K.3    Kondo, T.4    Yamanaka, H.5    Kobayashi, K.6    Dai, Y.7    Fukuoka, T.8    Sakagami, M.9    Noguchi, K.10
  • 50
    • 0028343494 scopus 로고
    • ATP-evoked increases in intracellular calcium in neurons and glia from the dorsal spinal cord
    • M.W. Salter, and J.L. Hicks ATP-evoked increases in intracellular calcium in neurons and glia from the dorsal spinal cord J Neurosci 14 1994 1563 1575
    • (1994) J Neurosci , vol.14 , pp. 1563-1575
    • Salter, M.W.1    Hicks, J.L.2
  • 51
    • 0034655788 scopus 로고    scopus 로고
    • P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes
    • S.R. Fam, C.J. Gallagher, and M.W. Salter P2Y(1) purinoceptor-mediated Ca(2+) signaling and Ca(2+) wave propagation in dorsal spinal cord astrocytes J Neurosci 20 2000 2800 2808
    • (2000) J Neurosci , vol.20 , pp. 2800-2808
    • Fam, S.R.1    Gallagher, C.J.2    Salter, M.W.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.