Suppressive effects of phosphodiesterase type IV inhibitors on rat cultured microglial cells: Comparison with other types of cAMP-elevating agents

Neuropharmacology

Volumn 42, Issue 2, 2002, Pages 262-269

  Zhang, Bo ^a   Yang, Lihua ^a   Konishi, Yoshihiro ^a   Maeda, Nobuji ^a   Sakanaka, Masahiro ^a   Tanaka, Junya ^a  

^a EHIME UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

cAMP; NO; Phosphodiesterase; Proliferation; Superoxide anion; TNF

Indexed keywords

4 (3 BUTOXY 4 METHOXYBENZYL) 2 IMIDAZOLIDINONE; 8 BROMO CYCLIC AMP; CYCLIC AMP; CYCLINE; FORSKOLIN; HEME DERIVATIVE; HEMEOXIGENASE 1; ISOPRENALINE; LIPOPOLYSACCHARIDE; MESSENGER RNA; METALLOTHIONEIN; NITRIC OXIDE; PHOSPHODIESTERASE IV; PHOSPHODIESTERASE IV INHIBITOR; ROLIPRAM; SUPEROXIDE; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; ASTROCYTE; CELL FUNCTION; CELL LEVEL; CELL PROLIFERATION; COCULTURE; CONTROLLED STUDY; DRUG EFFECT; EMBRYO; ENZYME ACTIVITY; ENZYME LINKED IMMUNOSORBENT ASSAY; IMMUNOCYTOCHEMISTRY; MICROGLIA; NERVE CELL CULTURE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT;

3',5'-CYCLIC-NUCLEOTIDE PHOSPHODIESTERASE; ANIMALS; ASTROCYTES; CELL DIVISION; CELLS, CULTURED; CEREBRAL CORTEX; CYCLIC AMP; ENZYME-LINKED IMMUNOSORBENT ASSAY; IMMUNOHISTOCHEMISTRY; MICROGLIA; NITRIC OXIDE; PHOSPHODIESTERASE INHIBITORS; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SUPEROXIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0036172694     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0028-3908(01)00174-5     Document Type: Article

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