CC-chemokine MIP-1α in the spinal cord contributes to nerve injury-induced neuropathic pain

Neuroscience Letters

Volumn 484, Issue 1, 2010, Pages 17-21

  Kiguchi, Norikazu ^a   Kobayashi, Yuka ^a   Maeda, Takehiko ^a   Saika, Fumihiro ^a   Kishioka, Shiroh ^a  

^a WAKAYAMA MEDICAL UNIVERSITY   (Japan)

Author keywords

Allodynia; CCL3; CCR1; CCR5; Chemokine; Hyperalgesia

Indexed keywords

CHEMOKINE RECEPTOR CCR1; CHEMOKINE RECEPTOR CCR5; GLYCERALDEHYDE 3 PHOSPHATE DEHYDROGENASE; MACROPHAGE INFLAMMATORY PROTEIN 1ALPHA; MESSENGER RNA; NEUTRALIZING ANTIBODY;

ALLODYNIA; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; HYPERALGESIA; MALE; MOUSE; NERVE INJURY; NERVE LIGATION; NEUROPATHIC PAIN; NONHUMAN; PERIPHERAL NERVE INJURY; PRIORITY JOURNAL; SCIATIC NERVE; SPINAL CORD; SPINAL CORD DORSAL HORN; UPREGULATION;

ANALYSIS OF VARIANCE; ANIMALS; CHEMOKINE CCL3; HYPERALGESIA; MALE; MICE; MICE, INBRED ICR; NEURALGIA; PAIN MEASUREMENT; RECEPTORS, CCR1; SCIATIC NERVE; SPINAL CORD;

EID: 84755161802     PISSN: 03043940     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neulet.2010.07.085     Document Type: Article

References (27)

1. Abbadie C. Chemokines, chemokine receptors and pain. Trends Immunol. 2005, 26:529-534.
2. Boddeke E.W., Meigel I., Frentzel S., Gourmala N.G., Harrison J.K., Buttini M., Spleiss O., Gebicke-Harter P. Cultured rat microglia express functional beta-chemokine receptors. J. Neuroimmunol. 1999, 98:176-184.
3. Charo I.F., Ransohoff R.M. The many roles of chemokines and chemokine receptors in inflammation. N. Engl. J. Med. 2006, 354:610-621.
4. Dominguez E., Rivat C., Pommier B., Mauborgne A., Pohl M. JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat. J. Neurochem. 2008, 107:50-60.
5. Dorf M.E., Berman M.A., Tanabe S., Heesen M., Luo Y. Astrocytes express functional chemokine receptors. J. Neuroimmunol. 2000, 111:109-121.
6. Gilron I., Bailey J.M., Tu D., Holden R.R., Weaver D.F., Houlden R.L. Morphine, gabapentin, or their combination for neuropathic pain. N. Engl. J. Med. 2005, 352:1324-1334.
7. Hylden J.L., Wilcox G.L. Intrathecal morphine in mice: a new technique. Eur. J. Pharmacol. 1980, 67:313-316.
8. Kiguchi N., Maeda T., Kobayashi Y., Fukazawa Y., Kishioka S. Activation of extracellular signal-regulated kinase in sciatic nerve contributes to neuropathic pain after partial sciatic nerve ligation in mice. Anesth. Analg. 2009, 109:1305-1311.
9. Kiguchi N., Maeda T., Kobayashi Y., Fukazawa Y., Kishioka S. Macrophage inflammatory protein-1alpha mediates the development of neuropathic pain following peripheral nerve injury through interleukin-1beta up-regulation. Pain 2010, 149:305-315.
10. Kiguchi N., Maeda T., Kobayashi Y., Kishioka S. Up-regulation of tumor necrosis factor-alpha in spinal cord contributes to vincristine-induced mechanical allodynia in mice. Neurosci. Lett. 2008.
11. Lentzsch S., Gries M., Janz M., Bargou R., Dorken B., Mapara M.Y. Macrophage inflammatory protein 1-alpha (MIP-1 alpha) triggers migration and signaling cascades mediating survival and proliferation in multiple myeloma (MM) cells. Blood 2003, 101:3568-3573.
12. Marchand F., Perretti M., McMahon S.B. Role of the immune system in chronic pain. Nat. Rev. Neurosci. 2005, 6:521-532.
13. Menten P., Wuyts A., Van Damme J. Macrophage inflammatory protein-1. Cytokine Growth Factor Rev. 2002, 13:455-481.
14. Moalem G., Tracey D.J. Immune and inflammatory mechanisms in neuropathic pain. Brain Res. Rev. 2006, 51:240-264.
15. Murphy G.M., Jia X.C., Song Y., Ong E., Shrivastava R., Bocchini V., Lee Y.L., Eng L.F. Macrophage inflammatory protein 1-alpha mRNA expression in an immortalized microglial cell line and cortical astrocyte cultures. J. Neurosci. Res. 1995, 40:755-763.
16. Obata K., Yamanaka H., Kobayashi K., Dai Y., Mizushima T., Katsura H., Fukuoka T., Tokunaga A., Noguchi K. Role of mitogen-activated protein kinase activation in injured and intact primary afferent neurons for mechanical and heat hypersensitivity after spinal nerve ligation. J. Neurosci. 2004, 24:10211-10222.
17. Scholz J., Woolf C.J. The neuropathic pain triad: neurons, immune cells and glia. Nat. Neurosci. 2007, 10:1361-1368.
18. Seltzer Z., Dubner R., Shir Y. A novel behavioral model of neuropathic pain disorders produced in rats by partial sciatic nerve injury. Pain 1990, 43:205-218.
19. Szabo I., Chen X.H., Xin L., Adler M.W., Howard O.M., Oppenheim J.J., Rogers T.J. Heterologous desensitization of opioid receptors by chemokines inhibits chemotaxis and enhances the perception of pain. Proc. Natl. Acad. Sci. U.S.A. 2002, 99:10276-10281.
20. Tsuda M., Inoue K., Salter M.W. Neuropathic pain and spinal microglia: a big problem from molecules in "small" glia. Trends Neurosci. 2005, 28:101-107.
21. Wells T.N., Power C.A., Shaw J.P., Proudfoot A.E. Chemokine blockers - therapeutics in the making?. Trends Pharmacol. Sci. 2006, 27:41-47.
22. White F.A., Jung H., Miller R.J. Chemokines and the pathophysiology of neuropathic pain. Proc. Natl. Acad. Sci. U.S.A. 2007, 104:20151-20158.
23. Wong M., Fish E.N. RANTES and MIP-1alpha activate stats in T cells. J. Biol. Chem. 1998, 273:309-314.
24. Woolf C.J., Mannion R.J. Neuropathic pain: aetiology, symptoms, mechanisms, and management. Lancet 1999, 353:1959-1964.
25. Zhang J., Shi X.Q., Echeverry S., Mogil J.S., De Koninck Y., Rivest S. Expression of CCR2 in both resident and bone marrow-derived microglia plays a critical role in neuropathic pain. J. Neurosci. 2007, 27:12396-12406.
26. Zhang N., Inan S., Cowan A., Sun R., Wang J.M., Rogers T.J., Caterina M., Oppenheim J.J. A proinflammatory chemokine, CCL3, sensitizes the heat- and capsaicin-gated ion channel TRPV1. Proc. Natl. Acad. Sci. U. S.A. 2005, 102:4536-4541.
27. Zhang N., Oppenheim J.J. Crosstalk between chemokines and neuronal receptors bridges immune and nervous systems. J. Leukocyte Biol. 2005, 78:1210-1214.